UA111480C2 - ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ЛІКУВАННЯ СИНДРОМУ ПОДРАЗНЕНОГО КИШЕЧНИКУ, ЯКА ВВОДИТЬСЯ ПЕРОРАЛЬНО, ЩО МІСТИТЬ ТРИМЕБУТИН, СИМЕТИКОН, α-D-ГАЛАКТОЗИДАЗУ, І СПОСІБ ЇЇ ОТРИМАННЯ - Google Patents
ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ЛІКУВАННЯ СИНДРОМУ ПОДРАЗНЕНОГО КИШЕЧНИКУ, ЯКА ВВОДИТЬСЯ ПЕРОРАЛЬНО, ЩО МІСТИТЬ ТРИМЕБУТИН, СИМЕТИКОН, α-D-ГАЛАКТОЗИДАЗУ, І СПОСІБ ЇЇ ОТРИМАННЯInfo
- Publication number
- UA111480C2 UA111480C2 UAA201307590A UAA201307590A UA111480C2 UA 111480 C2 UA111480 C2 UA 111480C2 UA A201307590 A UAA201307590 A UA A201307590A UA A201307590 A UAA201307590 A UA A201307590A UA 111480 C2 UA111480 C2 UA 111480C2
- Authority
- UA
- Ukraine
- Prior art keywords
- pharmaceutical formulation
- bowel syndrome
- irritable bowel
- agent
- simeticon
- Prior art date
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- A—HUMAN NECESSITIES
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
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- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/451—Non condensed piperidines, e.g. piperocaine having a carbocyclic group directly attached to the heterocyclic ring, e.g. glutethimide, meperidine, loperamide, phencyclidine, piminodine
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Abstract
Винахід стосується фармацевтичної композиції або складу, адаптованого для перорального введення в формі таблетки, покритої оболонкою таблетки або капсули для запобігання або лікування синдрому подразненого кишечнику, що включає повторюваний шлунково-кишковий дискомфорт або біль щонайменше протягом трьох діб на місяць протягом останніх трьох місяців, асоційований з двома або більше наступними станами: а) поліпшення при дефекації, b) поява, пов'язана зі зміною частоти випорожнень, і с) поява, пов'язана зі зміною зовнішнього вигляду випорожнень, де дискомфорт стосується неприємного відчуття, що не описане як біль, де склад складається з тримебутину або його фармацевтично прийнятної солі, симетикону, α-D-галактозидази, зв'язувального засобу, розріджувача, абсорбуючого засобу, дезінтегруючого засобу, змащувального засобу і засобу, що сприяє ковзанню.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| MX2010012479A MX2010012479A (es) | 2010-11-16 | 2010-11-16 | Composicion farmaceutica de administracion oral para el tratamiento del sindrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retencion de gases y enzimas digestivas y proceso para su preparacion. |
| PCT/MX2011/000138 WO2012067481A2 (es) | 2010-11-16 | 2011-11-15 | Composición farmacéutica de administración oral para el tratamiento del síndrome de intestino irritable, a base de un modificador de la motilidad intestinal, un agente que previene la retención de gases y enzimas digestivas y proceso para su preparación |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA111480C2 true UA111480C2 (uk) | 2016-05-10 |
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ID=46084557
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA201307590A UA111480C2 (uk) | 2010-11-16 | 2011-11-15 | ФАРМАЦЕВТИЧНА КОМПОЗИЦІЯ ДЛЯ ЛІКУВАННЯ СИНДРОМУ ПОДРАЗНЕНОГО КИШЕЧНИКУ, ЯКА ВВОДИТЬСЯ ПЕРОРАЛЬНО, ЩО МІСТИТЬ ТРИМЕБУТИН, СИМЕТИКОН, α-D-ГАЛАКТОЗИДАЗУ, І СПОСІБ ЇЇ ОТРИМАННЯ |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US20130344145A1 (uk) |
| EP (1) | EP2641598B1 (uk) |
| JP (2) | JP6166179B2 (uk) |
| KR (1) | KR101958031B1 (uk) |
| CN (1) | CN103429237A (uk) |
| AR (1) | AR083888A1 (uk) |
| AU (1) | AU2011329916B2 (uk) |
| BR (1) | BR112013012100B8 (uk) |
| CA (1) | CA2818129C (uk) |
| CL (1) | CL2013001331A1 (uk) |
| CO (1) | CO6731095A2 (uk) |
| CR (1) | CR20130219A (uk) |
| DO (1) | DOP2013000107A (uk) |
| EC (1) | ECSP13012642A (uk) |
| ES (1) | ES2685784T3 (uk) |
| GT (1) | GT201300119A (uk) |
| MA (1) | MA34729B1 (uk) |
| MX (1) | MX2010012479A (uk) |
| PE (2) | PE20140380A1 (uk) |
| PL (1) | PL2641598T3 (uk) |
| PT (1) | PT2641598T (uk) |
| PY (1) | PY1148070A (uk) |
| RS (1) | RS57857B1 (uk) |
| RU (1) | RU2581920C2 (uk) |
| TR (1) | TR201812643T4 (uk) |
| UA (1) | UA111480C2 (uk) |
| UY (1) | UY33733A (uk) |
| WO (1) | WO2012067481A2 (uk) |
| ZA (1) | ZA201303518B (uk) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP6385642B2 (ja) * | 2013-02-28 | 2018-09-05 | 小林製薬株式会社 | 内服用組成物 |
| US9402885B2 (en) * | 2013-07-15 | 2016-08-02 | Alfa Wassermann S.P.A. | Method of treating GERD with alpha and beta galactosidases |
| CA2920844A1 (en) * | 2013-08-09 | 2015-02-12 | Allergan Pharmaceuticals International Limited | Digestive enzyme composition suitable for enteral administration |
| WO2016114734A1 (en) * | 2015-01-16 | 2016-07-21 | Biofarma Ilaç Sanayi Ve Ticaret A. Ş. | Pharmaceutical formulation of trimebutine maleate and simethicone comprising acidifying agent |
| IT201700006355A1 (it) * | 2017-01-20 | 2018-07-20 | Neilos S R L | Composizione per il trattamento dei disturbi gastrointestinali |
| EP3758686B1 (en) | 2018-02-26 | 2024-11-06 | R.P. Scherer Technologies, LLC | Pharmaceutical dosage form for an emulsion of simethicone and loperamide |
| CN109200278A (zh) * | 2018-10-08 | 2019-01-15 | 毛玉坤 | 腔镜去粘液消泡剂及其制备方法 |
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| NZ233582A (en) * | 1989-05-16 | 1992-05-26 | Akpharma Inc Formerly Aek Dev | Oral composition comprising alpha-galactosidase |
| JPH03275622A (ja) * | 1990-03-26 | 1991-12-06 | Teisan Seiyaku Kk | マレイン酸トリメブチンを含有する経口固形製剤 |
| KR920002149A (ko) * | 1990-07-03 | 1992-02-28 | 안드레아 엘. 콜비 | 비스테로이드계 소염제에 의해 유발된 위장 장애 증상을 완화시키기 위한 약제 조성물 및 이를 완화시키는 방법 |
| EP0707492A1 (en) * | 1993-07-06 | 1996-04-24 | Merck & Co. Inc. | H 2? antagonist-gastrointestinal motility agent combinations |
| US6103260A (en) * | 1997-07-17 | 2000-08-15 | Mcneil-Ppc, Inc. | Simethicone/anhydrous calcium phosphate compositions |
| US20040092511A1 (en) * | 1999-12-10 | 2004-05-13 | Billstein Stephan Anthony | Pharmaceutical combinations and their use in treating gastrointestinal and abdominal viscera disorders |
| US6676933B2 (en) * | 2001-05-23 | 2004-01-13 | Osmotica Corp. | Pharmaceutical composition containing mosapride and pancreatin |
| KR100467147B1 (ko) * | 2002-06-25 | 2005-01-24 | 주식회사 서울제약 | 이중코팅층을 갖는 제피정의 제조방법 |
| MXPA05010819A (es) * | 2003-04-08 | 2006-03-30 | Progenics Pharm Inc | Uso de antagonistas de opioide perifericos, especialmente metilnaltrexona para tratar sindrome de intestino irritable. |
| US20070020249A1 (en) * | 2005-04-29 | 2007-01-25 | Downs Bernard W | Compositions for prevention and treatement of symptoms of gastrointestinal distress |
| US20070105878A1 (en) * | 2005-10-03 | 2007-05-10 | Andrew Reaume | Purine formulations and methods for managing disorders |
| DE102005049649A1 (de) * | 2005-10-18 | 2007-04-19 | Pro Natura Gesellschaft für gesunde Ernährung mbH | Zusammensetzung zur Linderung von Beschwerden des Magen-Darm-Trakts |
| CO5790164A1 (es) * | 2006-08-10 | 2007-08-31 | Procaps S A | Composicion farmaceutica solida que incluye en combinacion un agente regulador de la motilidad intestinal y un agente antiflatulento |
| JP2008056567A (ja) * | 2006-08-29 | 2008-03-13 | Kowa Co | 胃腸疾患の治療又は予防のための医薬 |
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