UA26428A - 3r,5s-(+)-7-[4-(4-фторфеhіл)-2,6-діізопропіл-5-метоксиметилпірид-3-іл]-3,5-дигідроксигептеhова кислота як іhгібітор біосиhтезу холестериhу - Google Patents

3r,5s-(+)-7-[4-(4-фторфеhіл)-2,6-діізопропіл-5-метоксиметилпірид-3-іл]-3,5-дигідроксигептеhова кислота як іhгібітор біосиhтезу холестериhу

Info

Publication number
UA26428A
UA26428A UA5010264A UA5010264A UA26428A UA 26428 A UA26428 A UA 26428A UA 5010264 A UA5010264 A UA 5010264A UA 5010264 A UA5010264 A UA 5010264A UA 26428 A UA26428 A UA 26428A
Authority
UA
Ukraine
Prior art keywords
diisopropyl
acid
hytherogy
fluorophehyl
dyhydroxyhephetic
Prior art date
Application number
UA5010264A
Other languages
English (en)
Russian (ru)
Inventor
Рольф АНГЕРБАУЕР
Рольф АНГЕРБАУЭР
Петер Фай
Вальтер Хюбш
Томас ФІЛІПС
Томас ФИЛИПС
Хільмар БІШОФФ
Хильмар БИШОФФ
Дітер Петцінна
Дитер Петцинна
Дельф ШМІДТ
Дельф ШМИДТ
Гюнтер ТОМАС
Original Assignee
Байєр Аг
Байер Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Байєр Аг, Байер Аг filed Critical Байєр Аг
Publication of UA26428A publication Critical patent/UA26428A/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)

Abstract

Винахід відноситься до заміщених піридином діоксигептенових кислот, зокрема, до нової 3R,5S-(+)-7-[4-(4-фторфеніл)-2,6-діізопропіл-5-метоксиметилпірид-3-іл]-3,5-діоксигептенової кислоти в еритро-(E) -конфігурації у вигляді фізіологічно переносимої солі металу, що служить як інгібітор біосинтезу холестерину.
UA5010264A 1990-12-14 1991-12-13 3r,5s-(+)-7-[4-(4-фторфеhіл)-2,6-діізопропіл-5-метоксиметилпірид-3-іл]-3,5-дигідроксигептеhова кислота як іhгібітор біосиhтезу холестериhу UA26428A (uk)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4040026A DE4040026A1 (de) 1990-12-14 1990-12-14 Substituierte pyridyl-dihydroxy-heptensaeure und deren salze

Publications (1)

Publication Number Publication Date
UA26428A true UA26428A (uk) 1999-08-30

Family

ID=6420376

Family Applications (1)

Application Number Title Priority Date Filing Date
UA5010264A UA26428A (uk) 1990-12-14 1991-12-13 3r,5s-(+)-7-[4-(4-фторфеhіл)-2,6-діізопропіл-5-метоксиметилпірид-3-іл]-3,5-дигідроксигептеhова кислота як іhгібітор біосиhтезу холестериhу

Country Status (4)

Country Link
DE (1) DE4040026A1 (uk)
RU (1) RU2026290C1 (uk)
UA (1) UA26428A (uk)
ZA (1) ZA919833B (uk)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR9610422A (pt) * 1995-08-30 1999-07-13 Searle & Co Derivados de meta-guanidina uréia tiouréia ou ácido aminobenzóico azacíclico como antagonistas de integrina
DK0869121T3 (da) * 1997-04-04 2004-09-20 Aventis Pharma Gmbh Hypolipidæmiske propanolaminderivater

Also Published As

Publication number Publication date
RU2026290C1 (ru) 1995-01-09
ZA919833B (en) 1992-09-30
DE4040026A1 (de) 1992-06-17

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