UA39926C2 - Полімерний кон'югат, фармацевтична композиція з протипухлинною активністю - Google Patents

Полімерний кон'югат, фармацевтична композиція з протипухлинною активністю

Info

Publication number
UA39926C2
UA39926C2 UA94005444A UA94005444A UA39926C2 UA 39926 C2 UA39926 C2 UA 39926C2 UA 94005444 A UA94005444 A UA 94005444A UA 94005444 A UA94005444 A UA 94005444A UA 39926 C2 UA39926 C2 UA 39926C2
Authority
UA
Ukraine
Prior art keywords
input
output
unit
control
content
Prior art date
Application number
UA94005444A
Other languages
English (en)
Inventor
Нікола Монгеллі
Никола Монгелли
Франческо АНГЕЛУЧЧІ
Франческо АНГЕЛУЧЧИ
Енріко Пезенті
Антоніо СУАРАТО
Антонио Суарато
Джованні Біазолі
Джованни Биазоли
Original Assignee
Фармація Енд Апджон С.П.А.
Фармация Энд Апджон С.П.А.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Фармація Енд Апджон С.П.А., Фармация Энд Апджон С.П.А. filed Critical Фармація Енд Апджон С.П.А.
Publication of UA39926C2 publication Critical patent/UA39926C2/uk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/58—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. poly[meth]acrylate, polyacrylamide, polystyrene, polyvinylpyrrolidone, polyvinylalcohol or polystyrene sulfonic acid resin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Epoxy Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Addition Polymer Or Copolymer, Post-Treatments, Or Chemical Modifications (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)

Abstract

Винахід відноситься до вимірювальної техніки і може бути використаний в гірничодобувній і гірничопереробній галузі народного господарства для оперативного контролю вмісту корисного компонента в гірничих виробленнях, масивах, дробленій і подрібненій гірничій масі, а також для каротажу свердловин і в службі технічного контролю (СТК), а також при відвантаженні товарної руди. Задачею винаходу є удосконалення пристрою автоматичного контролю вмісту корисного компонента в мінеральній сировині, що дозволяє підвищити точність контролю якості товарної руди, шляхом урахування і багаторазового, безперервного сканування нерівностей поверхні гірничої маси, що контролюється. Пристрій оперативного контролю вмісту корисного компонента в мінеральній сировині містить джерело, приймач гамма-випромінювання і каротажний зонд, приєднане через підсилювач-нормалізатор до першого входу лічильника імпульсів, другий вхід якого приєднаний до першого входу таймера, блок введення, виведення, оперативний запам'ятовуючий пристрій, постійний запам'ятовуючий пристрій і центральний процесор, сполучений через шини даних, адрес і управління з оперативним запам'ятовуючим пристроєм, блоком введення-виведення і таймером, при цьому вихід лічильника імпульсів приєднаний до одного входу блоку введення, другий вихід таймера і вихід блоку виведення приєднані до першого і другого входу блоку індикації відповідно, інтерфейс верхнього рівня, вхід якого приєднаний до виходу блоку висновку. Новим в приладі є те, що контролюється за рахунок того, що в відомий пристрій автоматичного випробовування вмісту корисного компонента в мінеральній сировині введений подвійний інверсійний зонд і електромеханічний блок, утримуючий електродвигун з редуктором, при цьому проба вміщується на диск блоку, що обертається, над яким жорстко фіксується подвійний інверсійний зондовий пристрій, що усуває вплив нерівностей поверхні гірничої маси.
UA94005444A 1992-06-19 1993-07-06 Полімерний кон'югат, фармацевтична композиція з протипухлинною активністю UA39926C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929213077A GB9213077D0 (en) 1992-06-19 1992-06-19 Polymerbound taxol derivatives
PCT/EP1993/001433 WO1994000156A1 (en) 1992-06-19 1993-06-07 Polymer-bound paclitaxel derivatives

Publications (1)

Publication Number Publication Date
UA39926C2 true UA39926C2 (uk) 2001-07-16

Family

ID=10717411

Family Applications (1)

Application Number Title Priority Date Filing Date
UA94005444A UA39926C2 (uk) 1992-06-19 1993-07-06 Полімерний кон'югат, фармацевтична композиція з протипухлинною активністю

Country Status (25)

Country Link
US (4) US5362831A (uk)
EP (1) EP0600062B1 (uk)
JP (1) JP3693340B2 (uk)
KR (1) KR100281606B1 (uk)
CN (1) CN1041281C (uk)
AT (1) ATE205725T1 (uk)
AU (2) AU659750B2 (uk)
CA (1) CA2112482A1 (uk)
CZ (1) CZ62094A3 (uk)
DE (1) DE69330776T2 (uk)
ES (1) ES2164663T3 (uk)
FI (1) FI940733A7 (uk)
GB (1) GB9213077D0 (uk)
HU (2) HUT67914A (uk)
IL (1) IL106023A (uk)
MX (1) MX9303598A (uk)
MY (1) MY109213A (uk)
NZ (1) NZ253116A (uk)
PL (1) PL173898B1 (uk)
RU (1) RU2130462C1 (uk)
SG (1) SG49248A1 (uk)
TW (1) TW266201B (uk)
UA (1) UA39926C2 (uk)
WO (1) WO1994000156A1 (uk)
ZA (1) ZA934388B (uk)

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ATE205725T1 (de) 2001-10-15
NZ253116A (en) 1996-05-28
EP0600062A1 (en) 1994-06-08
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US5719265A (en) 1998-02-17
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US5362831A (en) 1994-11-08
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US5569720A (en) 1996-10-29
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