UA64784C2 - Improvements in enzymatic synthesis of chiral amines - Google Patents

Improvements in enzymatic synthesis of chiral amines Download PDF

Info

Publication number: UA64784C2
Authority: UA; Ukraine
Prior art keywords: aminopropane; amino; amino group; transaminase; acid
Prior art date: 1998-03-11

Application number

UA2000105759A

Other languages

English (en)

Ukrainian (uk)

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1998-03-11

Filing date

1999-10-03

Publication date

2004-03-15

1999-10-03 Application filed filed Critical

2004-03-15 Publication of UA64784C2 publication Critical patent/UA64784C2/uk

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/001—Amines; Imines
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/005—Amino acids other than alpha- or beta amino acids, e.g. gamma amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/06—Alanine; Leucine; Isoleucine; Serine; Homoserine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
- C12P13/12—Methionine; Cysteine; Cystine
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
- C12P41/006—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by reactions involving C-N bonds, e.g. nitriles, amides, hydantoins, carbamates, lactames, transamination reactions, or keto group formation from racemic mixtures

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Health & Medical Sciences (AREA)
General Engineering & Computer Science (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Biotechnology (AREA)
Biochemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Microbiology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Analytical Chemistry (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

UA2000105759A 1998-03-11 1999-10-03 Improvements in enzymatic synthesis of chiral amines UA64784C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US7752098P	1998-03-11	1998-03-11
PCT/US1999/005150 WO1999046398A1 (en)	1998-03-11	1999-03-10	Improvements in the enzymatic synthesis of chiral amines

Publications (1)

Publication Number	Publication Date
UA64784C2 true UA64784C2 (en)	2004-03-15

Family

ID=22138554

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA2000105759A UA64784C2 (en)	1998-03-11	1999-10-03	Improvements in enzymatic synthesis of chiral amines

Country Status (23)

Country	Link
EP (1)	EP1075534B8 (de)
JP (1)	JP2002505884A (de)
KR (1)	KR20010034561A (de)
CN (1)	CN1154746C (de)
AT (1)	ATE295424T1 (de)
AU (1)	AU753904B2 (de)
BR (1)	BR9908797A (de)
CA (1)	CA2322605A1 (de)
CZ (1)	CZ295882B6 (de)
DE (1)	DE69925267T2 (de)
ES (1)	ES2243051T3 (de)
FI (1)	FI20001805A7 (de)
HU (1)	HUP0101056A3 (de)
MX (1)	MXPA00008573A (de)
NO (1)	NO319671B1 (de)
NZ (1)	NZ506405A (de)
PL (1)	PL342882A1 (de)
PT (1)	PT1075534E (de)
RU (1)	RU2213142C2 (de)
SK (1)	SK284352B6 (de)
TR (1)	TR200002604T2 (de)
UA (1)	UA64784C2 (de)
WO (1)	WO1999046398A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP1038953B1 (de) *	1999-03-19	2004-09-22	Sumitomo Chemical Company, Limited	Stereoselektive Transaminase, deren kodierende Gen und deren Verwendungen
JP2001190298A (ja) *	2000-01-13	2001-07-17	Kanegafuchi Chem Ind Co Ltd	光学活性ｎ−メチルアミノ酸の製造方法
EP1818411A1 (de) *	2006-02-13	2007-08-15	Lonza AG	Verfahren zur Herstellung von optisch aktiven chiralen Aminen
DE102007042600A1 (de)	2007-09-07	2009-03-12	Evonik Degussa Gmbh	Verfahren zur Herstellung von enantiomerenangereichten Aminen
HUE036104T2 (hu)	2009-01-08	2018-06-28	Codexis Inc	Transzamináz polipeptidek
JP5707344B2 (ja)	2009-02-26	2015-04-30	コデクシス，インコーポレイテッド	トランスアミナーゼ生体触媒
CN102597226B (zh)	2009-06-22	2015-08-19	科德克希思公司	转氨酶反应
EP2862938A3 (de) *	2009-09-02	2015-07-15	Lonza AG	Verfahren zur Identifikation und Herstellung von (R)-spezifischer Omega-Transaminase
DK2582799T3 (en)	2010-06-17	2018-02-12	Codexis Inc	BIOCATALATORS AND PROCEDURES FOR THE SYNTHESIS OF (S) -3- (1-AMINOETHYL) -PHENOL
US8932836B2 (en)	2010-08-16	2015-01-13	Codexis, Inc.	Biocatalysts and methods for the synthesis of (1R,2R)-2-(3,4-dimethoxyphenethoxy)cyclohexanamine
EP2744908A4 (de) *	2011-08-16	2015-05-27	Embio Ltd	Enzymatische synthese optisch aktiver chiraler amine
CN104630170A (zh) *	2013-11-08	2015-05-20	中国科学院天津工业生物技术研究所	一种来源于里氏木霉的新(r)-转氨酶及其应用
CN114134126B (zh) *	2021-10-28	2023-12-05	浙江大学杭州国际科创中心	转氨酶及其突变体在制备(s)-1-甲氧基-2-丙胺中的应用

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5300437A (en) *	1989-06-22	1994-04-05	Celgene Corporation	Enantiomeric enrichment and stereoselective synthesis of chiral amines
US4950606A (en) *	1989-06-22	1990-08-21	Celgene Corporation	Enantiomeric enrichment and stereoselective synthesis of chiral amines
WO1997015682A1 (en) *	1995-10-23	1997-05-01	Kaneka Corporation	Process for producing optically active amino compounds

1999
- 1999-03-10 AT AT99911250T patent/ATE295424T1/de not_active IP Right Cessation
- 1999-03-10 JP JP2000535765A patent/JP2002505884A/ja not_active Withdrawn
- 1999-03-10 PT PT99911250T patent/PT1075534E/pt unknown
- 1999-03-10 DE DE69925267T patent/DE69925267T2/de not_active Expired - Fee Related
- 1999-03-10 MX MXPA00008573A patent/MXPA00008573A/es active IP Right Grant
- 1999-03-10 EP EP99911250A patent/EP1075534B8/de not_active Expired - Lifetime
- 1999-03-10 CA CA002322605A patent/CA2322605A1/en not_active Abandoned
- 1999-03-10 RU RU2000125535/13A patent/RU2213142C2/ru active IP Right Revival
- 1999-03-10 ES ES99911250T patent/ES2243051T3/es not_active Expired - Lifetime
- 1999-03-10 NZ NZ506405A patent/NZ506405A/en not_active IP Right Cessation
- 1999-03-10 TR TR2000/02604T patent/TR200002604T2/xx unknown
- 1999-03-10 SK SK1338-2000A patent/SK284352B6/sk unknown
- 1999-03-10 AU AU29938/99A patent/AU753904B2/en not_active Ceased
- 1999-03-10 CZ CZ20003177A patent/CZ295882B6/cs not_active IP Right Cessation
- 1999-03-10 BR BR9908797-9A patent/BR9908797A/pt not_active IP Right Cessation
- 1999-03-10 CN CNB99803651XA patent/CN1154746C/zh not_active Expired - Fee Related
- 1999-03-10 WO PCT/US1999/005150 patent/WO1999046398A1/en not_active Ceased
- 1999-03-10 PL PL99342882A patent/PL342882A1/xx not_active IP Right Cessation
- 1999-03-10 HU HU0101056A patent/HUP0101056A3/hu unknown
- 1999-03-10 KR KR1020007009945A patent/KR20010034561A/ko not_active Abandoned
- 1999-10-03 UA UA2000105759A patent/UA64784C2/uk unknown
2000
- 2000-08-11 NO NO20004036A patent/NO319671B1/no unknown
- 2000-08-15 FI FI20001805A patent/FI20001805A7/fi not_active IP Right Cessation

Also Published As

Publication number	Publication date
MXPA00008573A (es)	2003-07-14
NO20004036L (no)	2000-10-27
FI20001805L (fi)	2000-08-15
NZ506405A (en)	2003-08-29
TR200002604T2 (tr)	2000-11-21
NO319671B1 (no)	2005-09-05
SK13382000A3 (sk)	2001-05-10
ES2243051T3 (es)	2005-11-16
NO20004036D0 (no)	2000-08-11
EP1075534A1 (de)	2001-02-14
EP1075534B8 (de)	2005-07-06
DE69925267T2 (de)	2006-01-26
PL342882A1 (en)	2001-07-16
RU2213142C2 (ru)	2003-09-27
JP2002505884A (ja)	2002-02-26
CZ20003177A3 (cs)	2000-12-13
PT1075534E (pt)	2005-09-30
CN1154746C (zh)	2004-06-23
HUP0101056A2 (hu)	2001-07-30
ATE295424T1 (de)	2005-05-15
HK1035000A1 (en)	2001-11-09
AU2993899A (en)	1999-09-27
DE69925267D1 (de)	2005-06-16
EP1075534B1 (de)	2005-05-11
CN1292828A (zh)	2001-04-25
WO1999046398A1 (en)	1999-09-16
HUP0101056A3 (en)	2006-03-28
EP1075534A4 (de)	2003-07-09
SK284352B6 (sk)	2005-02-04
CA2322605A1 (en)	1999-09-16
KR20010034561A (ko)	2001-04-25
BR9908797A (pt)	2000-12-12
AU753904B2 (en)	2002-10-31
FI20001805A7 (fi)	2000-09-11
CZ295882B6 (cs)	2005-11-16

Publication	Publication Date	Title
RU2087536C1 (ru)	1997-08-20	Способ энантиомерного обогащения смеси двух энантиомерных хиральных аминов
EP2064331B1 (de)	2014-04-02	Verfahren zur Herstellung von optisch aktiven N-geschütztem 3-Aminopyrrolidin oder N-geschütztem 3-Aminopiperidin durch Racematspaltung der Amine unter Verwendung einer omega-Transaminase
US4826766A (en)	1989-05-02	Production of amino acids using coupled aminotransferases
RU2213142C2 (ru)	2003-09-27	Способ получения хирального амина
SK286456B6 (sk)	2008-10-07	Spôsob výroby L-fosfinotricínu enzymatickou transamináciou s aspartátom
US5047585A (en)	1991-09-10	Process for racemizing an optically active N-benzylidene amino-acid amide
US6133018A (en)	2000-10-17	Enzymatic synthesis of chiral amines using -2-amino propane as amine donor
Winkler et al.	1995	Principles and results of stable isotope labelling of L-α-Aminoacids by combined chemical and enzymatic methods
HK1035000B (en)	2005-12-23	Improvements in the enzymatic synthesis of chiral amines
JPS62205781A (ja)	1987-09-10	シユ−ドモナス属菌株の培養方法
JPS59159789A (ja)	1984-09-10	Ｌ−α−アミノ酸の製造方法
JPH02124087A (ja)	1990-05-11	シユードモナス属細菌の培養方法
JPS62257392A (ja)	1987-11-09	トランスアミノ化によるｌ−アミノ酸の製法
CZ355697A3 (cs)	1998-06-17	Způsob stereoselektivní syntézy jedné chirální formy aminu