UA65525C2 - Capsules containing encapsulated cells, method for their preparation - Google Patents

Capsules containing encapsulated cells, method for their preparation Download PDF

Info

Publication number: UA65525C2
Authority: UA; Ukraine
Prior art keywords: cells; capsule; sulfate; capsule according; retroviral
Prior art date: 1995-06-27

Application number

UA97126354A

Other languages

English (en)

Ukrainian (uk)

Original Assignee

Bavarian Nordic As

Gsf Forschungszentrum Umwelt

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-06-27

Filing date

1996-06-24

Publication date

2004-04-15

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=8097001&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA65525(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1996-06-24 Application filed by Bavarian Nordic As, Gsf Forschungszentrum Umwelt filed Critical Bavarian Nordic As

2004-04-15 Publication of UA65525C2 publication Critical patent/UA65525C2/uk

Links

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JJICLMJFIKGAAU-UHFFFAOYSA-M sodium;2-amino-9-(1,3-dihydroxypropan-2-yloxymethyl)purin-6-olate Chemical compound [Na+].NC1=NC([O-])=C2N=CN(COC(CO)CO)C2=N1 JJICLMJFIKGAAU-UHFFFAOYSA-M 0.000 description 1
241000894007 species Species 0.000 description 1
238000003756 stirring Methods 0.000 description 1
239000000126 substance Substances 0.000 description 1
150000008054 sulfonate salts Chemical class 0.000 description 1
238000010998 test method Methods 0.000 description 1
QIWDGSYHBCMXSI-UHFFFAOYSA-J tetrasodium;(2-methyl-4-phosphonatooxynaphthalen-1-yl) phosphate;hexahydrate Chemical compound O.O.O.O.O.O.[Na+].[Na+].[Na+].[Na+].C1=CC=CC2=C(OP([O-])([O-])=O)C(C)=CC(OP([O-])([O-])=O)=C21 QIWDGSYHBCMXSI-UHFFFAOYSA-J 0.000 description 1
230000008467 tissue growth Effects 0.000 description 1
239000003053 toxin Substances 0.000 description 1
238000001890 transfection Methods 0.000 description 1
238000002054 transplantation Methods 0.000 description 1
GPRLSGONYQIRFK-MNYXATJNSA-N triton Chemical compound [3H+] GPRLSGONYQIRFK-MNYXATJNSA-N 0.000 description 1
238000005199 ultracentrifugation Methods 0.000 description 1
241000701161 unidentified adenovirus Species 0.000 description 1
241001529453 unidentified herpesvirus Species 0.000 description 1
235000020047 vermouth Nutrition 0.000 description 1
230000009385 viral infection Effects 0.000 description 1
238000005406 washing Methods 0.000 description 1
235000021119 whey protein Nutrition 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
- C12N15/86—Viral vectors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
- C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
- C12N11/04—Enzymes or microbial cells immobilised on or in an organic carrier entrapped within the carrier, e.g. gel or hollow fibres
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13021—Viruses as such, e.g. new isolates, mutants or their genomic sequences
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2740/00—Reverse transcribing RNA viruses
- C12N2740/00011—Details
- C12N2740/10011—Retroviridae
- C12N2740/13011—Gammaretrovirus, e.g. murine leukeamia virus
- C12N2740/13041—Use of virus, viral particle or viral elements as a vector
- C12N2740/13043—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector

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Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Genetics & Genomics (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Medicinal Chemistry (AREA)
Biotechnology (AREA)
Veterinary Medicine (AREA)
Animal Behavior & Ethology (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
General Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Epidemiology (AREA)
Microbiology (AREA)
Biochemistry (AREA)
Virology (AREA)
Molecular Biology (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Plant Pathology (AREA)
Immunology (AREA)
Physics & Mathematics (AREA)
Biophysics (AREA)
Dispersion Chemistry (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Medicinal Preparation (AREA)
Manufacturing Of Micro-Capsules (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Immobilizing And Processing Of Enzymes And Microorganisms (AREA)

UA97126354A 1995-06-27 1996-06-24 Capsules containing encapsulated cells, method for their preparation UA65525C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
DK74095		1995-06-27
PCT/EP1996/002748 WO1997001357A1 (en)	1995-06-27	1996-06-24	Encapsulated cells producing viral particles

Publications (1)

Publication Number	Publication Date
UA65525C2 true UA65525C2 (en)	2004-04-15

Family

ID=8097001

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UA97126354A UA65525C2 (en)	1995-06-27	1996-06-24	Capsules containing encapsulated cells, method for their preparation

Country Status (21)

Country	Link
US (1)	US6776985B1 (de)
EP (1)	EP0835137B1 (de)
JP (2)	JP4119952B2 (de)
KR (1)	KR100484883B1 (de)
CN (1)	CN1187095C (de)
AT (1)	ATE309000T1 (de)
AU (1)	AU708273B2 (de)
CA (1)	CA2222559A1 (de)
CZ (1)	CZ286979B6 (de)
DE (1)	DE69633180D1 (de)
DK (1)	DK0835137T3 (de)
ES (1)	ES2253754T3 (de)
IL (1)	IL122119A (de)
NO (1)	NO321427B1 (de)
NZ (1)	NZ312671A (de)
PL (1)	PL185338B1 (de)
PT (1)	PT835137E (de)
RU (1)	RU2187301C2 (de)
SI (1)	SI0835137T1 (de)
UA (1)	UA65525C2 (de)
WO (1)	WO1997001357A1 (de)

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JP3908274B2 (ja)	1995-03-09	2007-04-25	ゲーエスエフ−フォルシュンクスツェントラム・フュア・ウムベルト・ウント・ゲズントハイト・ゲーエムベーハー	遺伝子治療用の抗菌ペプチドをコードする治療用遺伝子を有するベクター
ATE309000T1 (de)	1995-06-27	2005-11-15	Bavarian Nordic As	Verkapselte zellen die virenpartikeln produzieren
US6540995B1 (en)	1996-03-27	2003-04-01	Bavarian Nordic Research Institute Gmbh	Encapsulated cells producing cytochrome P450
RU2185821C2 (ru)	1996-03-27	2002-07-27	Бавариан Нордик Рисерч Инститьют А/С	Трансдуцирующие цитохром р450 ретровирусные векторы
WO1999056660A1 (en)	1998-05-05	1999-11-11	Koninklijke Philips Electronics N.V.	Toothbrush comprising a brush member having a bristle field and an interdental bristle field
AU2005229434B2 (en)	2004-03-30	2010-09-30	Nsgene A/S	Therapeutic use of a growth factor, NsG33
JP2008540347A (ja)	2005-05-03	2008-11-20	フェテリネールメディツィニシュウニベルジテートウィーン	浸透性カプセル
CN101903049B (zh)	2007-12-20	2014-08-13	伊西康公司	包囊的肾组织
KR101250925B1 (ko) *	2011-10-28	2013-04-04	한화케미칼 주식회사	캡슐 세포용 구조체
GB201408233D0 (en)	2014-05-09	2014-06-25	Austrianova Singapore Pte Ltd	Use of polyanionic composition
FR3044016A1 (fr) *	2015-11-24	2017-05-26	Glaxosmithkline Ip Dev Ltd	Lignees cellulaires stables pour la production retrovirale
KR102067352B1 (ko) *	2015-11-24	2020-01-16	글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드	레트로바이러스 생산을 위한 일시적인 형질감염 방법
US11427809B2 (en)	2016-05-25	2022-08-30	Lonza Houston, Inc.	Methods for isolating adeno-associated virus using a polydialkylammonium salt
RU2688383C2 (ru) *	2017-07-10	2019-05-21	Федеральное государственное бюджетное образовательное учреждение высшего образования "Саратовский национальный исследовательский государственный университет имени Н.Г. Чернышевского"	Способ синтеза белка в культуре бактериальных клеток
CA3220737A1 (en) *	2021-05-21	2022-11-24	Bionaut Labs Ltd.	System and method for localized therapeutic treatment
CN115820683B (zh) *	2022-09-28	2024-04-05	西南大学	家蚕Cyp9a20基因及其应用

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US4391909A (en) *	1979-03-28	1983-07-05	Damon Corporation	Microcapsules containing viable tissue cells
DD160393A3 (de) *	1980-11-14	1983-07-27	Horst Dautzenberg	Mikrokapseln und verfahren zu ihrer herstellung
US4686098A (en) *	1984-05-14	1987-08-11	Merck & Co., Inc.	Encapsulated mouse cells transformed with avian retrovirus-bovine growth hormone DNA, and a method of administering BGH in vivo
US4680174A (en) *	1984-05-24	1987-07-14	Damon Biotech, Inc.	Induction of immune response by immunization with encapsulated antigen-producing cells
EP0199362A3 (de) *	1985-04-26	1987-10-07	Massachusetts Institute Of Technology	System und Vorrichtung zur verzögerten und stossweisen Freisetzung biologisch aktiver Substanzen
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WO1989011539A1 (en)	1988-05-17	1989-11-30	Sloan-Kettering Institute For Cancer Research	Retroviral vector
US5328470A (en) *	1989-03-31	1994-07-12	The Regents Of The University Of Michigan	Treatment of diseases by site-specific instillation of cells or site-specific transformation of cells and kits therefor
DE4021050A1 (de) *	1990-06-29	1992-01-02	Akad Wissenschaften Ddr	Verfahren zur herstellung von mikrokapseln
CA2051288C (en) *	1990-09-14	2002-02-05	Robert L. Martuza	Viral targeted destruction of neoplastic cells
WO1992010564A1 (en) *	1990-12-13	1992-06-25	The United States Of America, As Represented By The Secretary, U.S. Department Of Commerce	Sustained and continuous production of high titers of recombinant viral vectors and transduced target cells for use in gene therapy
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CA2198210C (en)	1994-09-02	2006-07-11	Gsf - Forschungszentrum Fur Umwelt Und Gesundheit Gmbh	Non self-inactivating, expression targeted retroviral vectors
ATE309000T1 (de)	1995-06-27	2005-11-15	Bavarian Nordic As	Verkapselte zellen die virenpartikeln produzieren
DK0848757T3 (da)	1995-09-06	2002-07-01	Austrian Nordic Biotherapeutic	Anvendelse af WAP eller MMTV regulatoriske sekvenser for målrettet ekspression af sammenkædede heterologe gener i humane mammae celler, inklusiv humane mammae carcinoma celler
RU2185821C2 (ru)	1996-03-27	2002-07-27	Бавариан Нордик Рисерч Инститьют А/С	Трансдуцирующие цитохром р450 ретровирусные векторы

1996
- 1996-06-24 AT AT96923905T patent/ATE309000T1/de not_active IP Right Cessation
- 1996-06-24 EP EP96923905A patent/EP0835137B1/de not_active Expired - Lifetime
- 1996-06-24 DE DE69633180T patent/DE69633180D1/de not_active Expired - Lifetime
- 1996-06-24 IL IL12211996A patent/IL122119A/en not_active IP Right Cessation
- 1996-06-24 JP JP50416597A patent/JP4119952B2/ja not_active Expired - Lifetime
- 1996-06-24 CA CA002222559A patent/CA2222559A1/en not_active Abandoned
- 1996-06-24 PT PT96923905T patent/PT835137E/pt unknown
- 1996-06-24 DK DK96923905T patent/DK0835137T3/da active
- 1996-06-24 ES ES96923905T patent/ES2253754T3/es not_active Expired - Lifetime
- 1996-06-24 KR KR1019970709807A patent/KR100484883B1/ko not_active Expired - Lifetime
- 1996-06-24 SI SI9630729T patent/SI0835137T1/sl unknown
- 1996-06-24 NZ NZ312671A patent/NZ312671A/xx not_active IP Right Cessation
- 1996-06-24 CN CNB961950501A patent/CN1187095C/zh not_active Expired - Fee Related
- 1996-06-24 PL PL96324289A patent/PL185338B1/pl not_active IP Right Cessation
- 1996-06-24 AU AU64154/96A patent/AU708273B2/en not_active Expired
- 1996-06-24 RU RU98101362/13A patent/RU2187301C2/ru not_active IP Right Cessation
- 1996-06-24 WO PCT/EP1996/002748 patent/WO1997001357A1/en not_active Ceased
- 1996-06-24 UA UA97126354A patent/UA65525C2/uk unknown
- 1996-06-24 CZ CZ19974195A patent/CZ286979B6/cs not_active IP Right Cessation
1997
- 1997-12-10 NO NO19975813A patent/NO321427B1/no not_active IP Right Cessation
- 1997-12-23 US US08/996,460 patent/US6776985B1/en not_active Expired - Lifetime
2007
- 2007-11-21 JP JP2007301109A patent/JP4848348B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
PL185338B1 (pl)	2003-04-30
EP0835137B1 (de)	2005-11-09
AU6415496A (en)	1997-01-30
IL122119A (en)	2004-06-01
ES2253754T3 (es)	2006-06-01
KR19990028491A (ko)	1999-04-15
NZ312671A (en)	1999-10-28
DK0835137T3 (da)	2006-03-06
KR100484883B1 (ko)	2005-09-02
CZ419597A3 (cs)	1998-03-18
CZ286979B6 (en)	2000-08-16
RU2187301C2 (ru)	2002-08-20
HK1010139A1 (en)	1999-06-17
JPH11508768A (ja)	1999-08-03
AU708273B2 (en)	1999-07-29
CN1187095C (zh)	2005-02-02
DE69633180D1 (de)	2004-09-23
PT835137E (pt)	2004-12-31
NO321427B1 (no)	2006-05-08
JP2008101011A (ja)	2008-05-01
EP0835137A1 (de)	1998-04-15
NO975813L (no)	1998-02-23
JP4848348B2 (ja)	2011-12-28
JP4119952B2 (ja)	2008-07-16
US6776985B1 (en)	2004-08-17
IL122119A0 (en)	1998-04-05
SI0835137T1 (sl)	2006-04-30
CA2222559A1 (en)	1997-01-16
PL324289A1 (en)	1998-05-11
NO975813D0 (no)	1997-12-10
WO1997001357A1 (en)	1997-01-16
ATE309000T1 (de)	2005-11-15
CN1189104A (zh)	1998-07-29

Publication	Publication Date	Title
JP4848348B2 (ja)	2011-12-28	ウイルス粒子産生カプセル化細胞
CA2450650C (en)	2007-08-28	Encapsulated cell therapy
JPH05505944A (ja)	1993-09-02	修飾肝細胞およびその用途
Basic et al.	1996	Microencapsulation and transplantation of genetically engineered cells: a new approach to somatic gene therapy
Lahooti et al.	2000	Agarose enhances the viability of intraperitoneally implanted microencapsulated L929 fibroblasts
Catena et al.	2010	Improvement of the monitoring and biosafety of encapsulated cells using the SFGNESTGL triple reporter system
US20070172465A1 (en)	2007-07-26	Use of umbilical cord blood stem cells to treat ischemic event
AU724537C (en)	2001-07-19	Method for gene transfer to the central nervous system
JPH09503662A (ja)	1997-04-15	インシュリン分泌細胞系、その製造方法と使用
US20090196854A1 (en)	2009-08-06	Methods and compositions for use of crl 5803 cells for expression of biotherapeutics and encapsulated cell-based delivery
CN100418582C (zh)	2008-09-17	一种促进骨再生的微胶囊及其应用
JP3609395B2 (ja)	2005-01-12	哺乳類の不死化肝臓細胞
US20050256067A1 (en)	2005-11-17	Method of preparing a treatment product, treatment product and a plasmid construct
AU7248100A (en)	2001-03-22	Method for gene transfer to the central nervous system
Armeanu et al.	2001	In vivo perivascular implantation of encapsulated packaging cells for prolonged retroviral gene transfer
KR20120123225A (ko)	2012-11-08	피막된 이식세포 분리방법
HK1021801B (en)	2007-05-11	Composition for gene transfer to the central nervous system
Saller et al.	2000	Macrocapsules as a novel alternative for systemic in vivo delivery of virus vector
HK1010139B (en)	2005-05-20	Encapsulated cells producing viral particles