UA66930C2 - Производные 4'-демикарозил-8а-аза-8а-гомотилозина - Google Patents

Производные 4'-демикарозил-8а-аза-8а-гомотилозина

Info

Publication number
UA66930C2
UA66930C2 UA2001129085A UA2001129085A UA66930C2 UA 66930 C2 UA66930 C2 UA 66930C2 UA 2001129085 A UA2001129085 A UA 2001129085A UA 2001129085 A UA2001129085 A UA 2001129085A UA 66930 C2 UA66930 C2 UA 66930C2
Authority
UA
Ukraine
Prior art keywords
derivatives
homotylosin
demycarosyl
aza
acyl
Prior art date
Application number
UA2001129085A
Other languages
English (en)
Ukrainian (uk)
Inventor
Невенка ЛОПОТАР
Амалія Нарандя
Стєпан Мутак
Original Assignee
Пліва Д.Д.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Пліва Д.Д. filed Critical Пліва Д.Д.
Publication of UA66930C2 publication Critical patent/UA66930C2/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cephalosporin Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Saccharide Compounds (AREA)

Abstract

Настоящее изобретение касается производных 4'-демикарозил-8a-аза-8a-гомотилозина формулы I , где R означает CHO, CH(OCH3)2 или CH2N[CH2(C6H5)]2, R1 означает H или С1-C3 ацил, R2 означает OR6, и R6 означает H или С1-C3 ацил, R3 означает H, или R2 и R3 вместе означают =О, R4 означает OH, R5 означает H, или R4 и R5 вместе означают =O, и способа их получения. Новые производные проявляют противомикробное действие и могут также использоваться как промежуточные соединения при получении новых 17-членных азалидных антибиотиков.
UA2001129085A 1999-06-11 2000-06-06 Производные 4'-демикарозил-8а-аза-8а-гомотилозина UA66930C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HR990192A HRP990192A2 (en) 1999-06-11 1999-06-11 4'-DEMICAROZYL-8a-AZA-8a-HOMOTHILOSINE DERIVATIVES
PCT/HR2000/000018 WO2000077016A1 (en) 1999-06-11 2000-06-06 DERIVATIVES OF 4'-DEMYCAROSYL-8a-AZA-8a-HOMOTYLOSIN

Publications (1)

Publication Number Publication Date
UA66930C2 true UA66930C2 (ru) 2004-06-15

Family

ID=10946940

Family Applications (1)

Application Number Title Priority Date Filing Date
UA2001129085A UA66930C2 (ru) 1999-06-11 2000-06-06 Производные 4'-демикарозил-8а-аза-8а-гомотилозина

Country Status (13)

Country Link
EP (1) EP1189914A1 (ru)
JP (1) JP2003502338A (ru)
AU (1) AU767543B2 (ru)
CA (1) CA2375812A1 (ru)
CZ (1) CZ20014362A3 (ru)
EA (1) EA200200026A1 (ru)
HR (1) HRP990192A2 (ru)
HU (1) HUP0201610A3 (ru)
NO (1) NO322424B1 (ru)
SK (1) SK17572001A3 (ru)
UA (1) UA66930C2 (ru)
WO (1) WO2000077016A1 (ru)
YU (1) YU87401A (ru)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR043050A1 (es) 2002-09-26 2005-07-13 Rib X Pharmaceuticals Inc Compuestos heterociclicos bifuncionales y metodos para preparar y usar los mismos
BRPI0408117A (pt) * 2003-03-05 2006-03-01 Rib X Pharmaceuticals Inc compostos heterocìclicos bifuncionais e métodos de produção e uso dos mesmos
WO2005019238A1 (ja) 2003-08-22 2005-03-03 Meiji Seika Kaisha, Ltd. 新規アザライド及びアザラクタム誘導体とその製造法
EP2716647A3 (en) 2004-02-27 2014-08-20 Rib-X Pharmaceuticals, Inc. Macrocyclic compounds and methods of making and using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SI8710674B (sl) * 1987-04-14 1998-06-30 Pliva Postopek za pripravo 10,11,12,13-tetrahidro derivatov tilozina
SI8911498B (sl) * 1989-07-26 1998-10-31 Pliva Postopek za pripravo derivatov tilozina
CZ211798A3 (cs) * 1997-07-16 1999-02-17 Pliva, Farmaceutska, Kemijska, Prehrambena I Kozmetička Industrije, Dioničko Društvo Lineární 8a-sekoazalidy a způsob jejich výroby

Also Published As

Publication number Publication date
EP1189914A1 (en) 2002-03-27
HUP0201610A2 (en) 2002-10-28
SK17572001A3 (sk) 2002-04-04
YU87401A (sh) 2004-07-15
NO322424B1 (no) 2006-10-02
CA2375812A1 (en) 2000-12-21
WO2000077016A1 (en) 2000-12-21
CZ20014362A3 (cs) 2002-04-17
NO20016030L (no) 2002-01-30
NO20016030D0 (no) 2001-12-10
AU5558300A (en) 2001-01-02
AU767543B2 (en) 2003-11-13
HRP990192A2 (en) 2001-04-30
EA200200026A1 (ru) 2002-06-27
HUP0201610A3 (en) 2003-03-28
JP2003502338A (ja) 2003-01-21

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