UA68324C2 - Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) - Google Patents

Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) Download PDF

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Publication number
UA68324C2
UA68324C2 UA97020840A UA97020840A UA68324C2 UA 68324 C2 UA68324 C2 UA 68324C2 UA 97020840 A UA97020840 A UA 97020840A UA 97020840 A UA97020840 A UA 97020840A UA 68324 C2 UA68324 C2 UA 68324C2
Authority
UA
Ukraine
Prior art keywords
peptide
clover
fact
monomers
ite
Prior art date
Application number
UA97020840A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of UA68324C2 publication Critical patent/UA68324C2/uk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
UA97020840A 1994-08-26 1995-08-25 Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) UA68324C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK98394 1994-08-26
PCT/DK1995/000343 WO1996006861A1 (en) 1994-08-26 1995-08-25 Trefoil peptide dimer

Publications (1)

Publication Number Publication Date
UA68324C2 true UA68324C2 (en) 2004-08-16

Family

ID=8099704

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97020840A UA68324C2 (en) 1994-08-26 1995-08-25 Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants)

Country Status (21)

Country Link
EP (2) EP1739091A1 (de)
JP (3) JPH10504720A (de)
KR (1) KR100255911B1 (de)
CN (1) CN1070867C (de)
AT (1) ATE329929T1 (de)
AU (1) AU694796B2 (de)
BR (1) BR9508773A (de)
CA (1) CA2196876C (de)
CZ (2) CZ289705B6 (de)
DE (1) DE69535060T2 (de)
DK (1) DK0777687T3 (de)
ES (1) ES2267104T3 (de)
FI (1) FI119989B (de)
HU (1) HU226921B1 (de)
MX (1) MX9701239A (de)
NO (1) NO323642B1 (de)
PL (1) PL184516B1 (de)
PT (1) PT777687E (de)
RU (1) RU2162857C2 (de)
UA (1) UA68324C2 (de)
WO (1) WO1996006861A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6221840B1 (en) * 1991-02-14 2001-04-24 The General Hospital Corporation Intestinal trefoil proteins
US6063755A (en) 1991-02-14 2000-05-16 The General Hospital Corporation Intestinal trefoil proteins
US6337195B1 (en) 1995-06-06 2002-01-08 Human Genome Sciences, Inc. Colon specific genes and proteins
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
WO1999010377A1 (en) 1997-08-25 1999-03-04 The General Hospital Corporation Receptor for intestinal trefoil factor
AU6523901A (en) * 2000-05-26 2001-12-11 Diadexus Inc Method of diagnosing, monitoring, staging, imaging and treating colon cancer
WO2002046226A2 (en) * 2000-12-08 2002-06-13 Novo Nordisk A/S Trefoil factor 2 (tff2) peptides with moiety attached to asn15
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
EP1842858A3 (de) * 2001-04-24 2008-04-02 The General Hospital Corporation Verfahren und Zusammensetzungen zur Behandlung von Verletzungen des Mundes und der Speiseröhre
CN1520309A (zh) * 2001-04-24 2004-08-11 综合医院公司 治疗口腔及食道损伤的方法和组合物
WO2002102403A1 (en) * 2001-06-14 2002-12-27 Novo Nordisk A/S Mucosal repair by tff dimer peptides
RU2224797C2 (ru) * 2002-04-04 2004-02-27 Эльдаров Михаил Анатольевич Рекомбинантная плазмидная днк pacyclans для переноса и экспрессии в клетках escherichia coli гена l-аспарагиназы erwinia carotovora (ecar-lans) и способ получения рекомбинантной ecar-lans из биомассы штамма e.coli-продуцента
WO2003068817A1 (en) * 2002-02-11 2003-08-21 Novo Nordisk A/S Management of mucosal viscosity by tff monomer peptides
JP2005527547A (ja) * 2002-03-26 2005-09-15 ザ ジェネラル ホスピタル コーポレーション トレフォイル・ペプチドを使用した組み合わせ療法
CA2552043A1 (en) 2004-01-21 2005-08-04 Novo Nordisk A/S Transglutaminase mediated conjugation of peptides
EP2575864A1 (de) 2010-06-04 2013-04-10 Trifoilium ApS Kleeblattfaktoren zur behandlung von chronischen lungenleiden
CN102526702A (zh) * 2010-12-23 2012-07-04 中国医学科学院基础医学研究所 小肽tff3治疗代谢综合征的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO884054D0 (no) * 1988-09-13 1988-09-13 Bio Tech As Nytt pentapeptid og fremgangsmaate for fremstilling derav.
WO1992014837A1 (en) * 1991-02-14 1992-09-03 The General Hospital Corporation Intestinal trefoil proteins

Also Published As

Publication number Publication date
HUT77917A (hu) 1998-10-28
JPH10504720A (ja) 1998-05-12
EP1739091A1 (de) 2007-01-03
EP0777687B1 (de) 2006-06-14
CA2196876C (en) 2007-04-17
FI970783L (fi) 1997-02-25
HU226921B1 (en) 2010-03-01
DE69535060D1 (de) 2006-07-27
FI970783A0 (fi) 1997-02-25
JP2007161720A (ja) 2007-06-28
WO1996006861A1 (en) 1996-03-07
NO970844L (no) 1997-04-28
ATE329929T1 (de) 2006-07-15
DE69535060T2 (de) 2006-12-28
FI119989B (fi) 2009-05-29
CZ289864B6 (cs) 2002-04-17
CA2196876A1 (en) 1996-03-07
JP2002191385A (ja) 2002-07-09
PL318785A1 (en) 1997-07-07
NO970844D0 (no) 1997-02-25
RU2162857C2 (ru) 2001-02-10
DK0777687T3 (da) 2006-10-16
BR9508773A (pt) 1997-12-30
PT777687E (pt) 2006-10-31
CZ289705B6 (cs) 2002-03-13
EP0777687A1 (de) 1997-06-11
AU694796B2 (en) 1998-07-30
CN1156459A (zh) 1997-08-06
PL184516B1 (pl) 2002-11-29
KR100255911B1 (ko) 2000-05-01
ES2267104T3 (es) 2007-03-01
AU3341595A (en) 1996-03-22
NO323642B1 (no) 2007-06-18
JP4156829B2 (ja) 2008-09-24
CZ54897A3 (en) 1997-08-13
MX9701239A (es) 1997-05-31
CN1070867C (zh) 2001-09-12

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