UA68324C2 - Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) - Google Patents

Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) Download PDF

Info

Publication number
UA68324C2
UA68324C2 UA97020840A UA97020840A UA68324C2 UA 68324 C2 UA68324 C2 UA 68324C2 UA 97020840 A UA97020840 A UA 97020840A UA 97020840 A UA97020840 A UA 97020840A UA 68324 C2 UA68324 C2 UA 68324C2
Authority
UA
Ukraine
Prior art keywords
peptide
clover
fact
monomers
ite
Prior art date
Application number
UA97020840A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of UA68324C2 publication Critical patent/UA68324C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
UA97020840A 1994-08-26 1995-08-25 Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants) UA68324C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK98394 1994-08-26
PCT/DK1995/000343 WO1996006861A1 (en) 1994-08-26 1995-08-25 Trefoil peptide dimer

Publications (1)

Publication Number Publication Date
UA68324C2 true UA68324C2 (en) 2004-08-16

Family

ID=8099704

Family Applications (1)

Application Number Title Priority Date Filing Date
UA97020840A UA68324C2 (en) 1994-08-26 1995-08-25 Dimers of "cloverleaf" peptide (variants), method for their production (variants) and pharmaceutical composition (variants)

Country Status (21)

Country Link
EP (2) EP0777687B1 (de)
JP (3) JPH10504720A (de)
KR (1) KR100255911B1 (de)
CN (1) CN1070867C (de)
AT (1) ATE329929T1 (de)
AU (1) AU694796B2 (de)
BR (1) BR9508773A (de)
CA (1) CA2196876C (de)
CZ (2) CZ289705B6 (de)
DE (1) DE69535060T2 (de)
DK (1) DK0777687T3 (de)
ES (1) ES2267104T3 (de)
FI (1) FI119989B (de)
HU (1) HU226921B1 (de)
MX (1) MX9701239A (de)
NO (1) NO323642B1 (de)
PL (1) PL184516B1 (de)
PT (1) PT777687E (de)
RU (1) RU2162857C2 (de)
UA (1) UA68324C2 (de)
WO (1) WO1996006861A1 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063755A (en) 1991-02-14 2000-05-16 The General Hospital Corporation Intestinal trefoil proteins
US6221840B1 (en) * 1991-02-14 2001-04-24 The General Hospital Corporation Intestinal trefoil proteins
US6337195B1 (en) 1995-06-06 2002-01-08 Human Genome Sciences, Inc. Colon specific genes and proteins
US6525018B1 (en) 1999-05-17 2003-02-25 The General Hospital Corp. Treating eye disorders using intestinal trefoil proteins
WO1999010377A1 (en) 1997-08-25 1999-03-04 The General Hospital Corporation Receptor for intestinal trefoil factor
EP1292675A2 (de) * 2000-05-26 2003-03-19 Diadexus, Inc. Verfahren zur diagnose, überwachung, klassifizierung, bildgebung und behandlung von kolonkrebs
EP1341817A2 (de) * 2000-12-08 2003-09-10 Novo Nordisk A/S Tff-peptide
EP1842858A3 (de) * 2001-04-24 2008-04-02 The General Hospital Corporation Verfahren und Zusammensetzungen zur Behandlung von Verletzungen des Mundes und der Speiseröhre
EP1383527A4 (de) * 2001-04-24 2004-07-14 Gen Hospital Corp Verfahren und zusammensetzungen zur behandlung von mund- und speiseröhrenläsionen
US20030186880A1 (en) * 2002-03-26 2003-10-02 Podolsky Daniel K. Combination therapy using trefoil peptides
US7538082B2 (en) 2001-04-24 2009-05-26 The General Hospital Corporation Methods and compositions for treating oral and esophageal lesions
EP1401481A1 (de) * 2001-06-14 2004-03-31 Novo Nordisk A/S Schleimhautreparatur mit tff-dimer-peptiden
RU2224797C2 (ru) * 2002-04-04 2004-02-27 Эльдаров Михаил Анатольевич Рекомбинантная плазмидная днк pacyclans для переноса и экспрессии в клетках escherichia coli гена l-аспарагиназы erwinia carotovora (ecar-lans) и способ получения рекомбинантной ecar-lans из биомассы штамма e.coli-продуцента
WO2003068817A1 (en) * 2002-02-11 2003-08-21 Novo Nordisk A/S Management of mucosal viscosity by tff monomer peptides
EP2033662B1 (de) 2004-01-21 2012-10-17 Novo Nordisk Health Care AG Transglutaminase vermittelte konjugation von peptiden.
EP2575864A1 (de) 2010-06-04 2013-04-10 Trifoilium ApS Kleeblattfaktoren zur behandlung von chronischen lungenleiden
CN102526702A (zh) * 2010-12-23 2012-07-04 中国医学科学院基础医学研究所 小肽tff3治疗代谢综合征的用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO884054D0 (no) * 1988-09-13 1988-09-13 Bio Tech As Nytt pentapeptid og fremgangsmaate for fremstilling derav.
WO1992014837A1 (en) * 1991-02-14 1992-09-03 The General Hospital Corporation Intestinal trefoil proteins

Also Published As

Publication number Publication date
AU694796B2 (en) 1998-07-30
DE69535060T2 (de) 2006-12-28
RU2162857C2 (ru) 2001-02-10
CN1156459A (zh) 1997-08-06
JP4156829B2 (ja) 2008-09-24
CZ54897A3 (en) 1997-08-13
CZ289705B6 (cs) 2002-03-13
MX9701239A (es) 1997-05-31
CN1070867C (zh) 2001-09-12
EP0777687B1 (de) 2006-06-14
NO323642B1 (no) 2007-06-18
PL184516B1 (pl) 2002-11-29
DK0777687T3 (da) 2006-10-16
HUT77917A (hu) 1998-10-28
EP1739091A1 (de) 2007-01-03
JP2002191385A (ja) 2002-07-09
CA2196876C (en) 2007-04-17
PL318785A1 (en) 1997-07-07
KR100255911B1 (ko) 2000-05-01
NO970844L (no) 1997-04-28
CA2196876A1 (en) 1996-03-07
FI970783L (fi) 1997-02-25
ES2267104T3 (es) 2007-03-01
JPH10504720A (ja) 1998-05-12
AU3341595A (en) 1996-03-22
EP0777687A1 (de) 1997-06-11
WO1996006861A1 (en) 1996-03-07
HU226921B1 (en) 2010-03-01
FI970783A0 (fi) 1997-02-25
JP2007161720A (ja) 2007-06-28
ATE329929T1 (de) 2006-07-15
BR9508773A (pt) 1997-12-30
CZ289864B6 (cs) 2002-04-17
DE69535060D1 (de) 2006-07-27
PT777687E (pt) 2006-10-31
FI119989B (fi) 2009-05-29
NO970844D0 (no) 1997-02-25

Similar Documents

Publication Publication Date Title
EP0293357B1 (de) Expression von menschlichem Proapolipoprotein A-1
UA70283C2 (en) Peptide (variants), a pharmaceutical composition cpeptide (variants), a pharmaceutical composition composed of peptide and a method for the preparatioomposed of peptide and a method for the preparation thereof (variants) n thereof (variants)
US20100317600A1 (en) Process for Preparing Cardiodilatin Fragments; Highly Purified Cardiodilatin Fragments and Intermediate Products for the Preparation of Same
RU2162857C2 (ru) Димер "клеверного" пептида
FI87800C (fi) Foerfarande foer framstaellning av glukagon i jaest
KR20150008870A (ko) 락토페린 융합 단백질 및 그의 제조방법
CA3087835A1 (en) Modified protein
CN113150172A (zh) Glp-1r/gipr双靶点激动剂融合蛋白及其制备方法与应用
WO2023227133A1 (zh) 人胰淀素类似物、其衍生物及用途
EP4678741A1 (de) Mrna-impfstoff gegen das respiratorische synzytialvirus und herstellungsverfahren dafür und verwendung davon
EP0362259B1 (de) Verfahren zur herstellung von cystatin-c oder abwandlungen davon und dns-sequenz zur ausführung dieser methode
JPH03503596A (ja) 蛋白質若しくはポリペプチドの調製方法、該ポリペプチドをコードするdna配列、該dna配列およびポリペプチドを有する微生物および該ポリペプチドの薬学的製剤としての利用
Li et al. Optimized functional and structural design of dual-target LMRAP, a bifunctional fusion protein with a 25-amino-acid antitumor peptide and GnRH Fc fragment
US11980671B2 (en) Use of bacterial voltage gated ion channels for human therapies
CN104693300B (zh) 改良型聚乙二醇化重组人干扰素α2b
KR102444019B1 (ko) 아프리카 돼지열병의 예방을 위한 항원 생산용 재조합 벡터 및 이의 용도
CN111363048B (zh) 一种具有穿膜活性的可溶性重组苦荞金属硫蛋白FtMT及其制备方法
US10179802B2 (en) Conotoxin peptide κ-CPTX-BTL04, preparation method therefor, and uses thereof
CN106146667B (zh) 一种Exendin-4融合蛋白及其制备方法与用途
KR20180114684A (ko) 신규한 Stx2e 에피토프 단백질 및 이를 포함하는 백신 조성물
JP5019442B2 (ja) 心筋の収縮を抑制するグラモストラ・スパチュラタ由来のポリペプチドおよびその遺伝子。
EP4606898A1 (de) Zellenoberflächen-hochanzeigetechnologie mit einem extrazellulären membran-lipoprotein-prsa-anzeigesystem
JP2002534960A (ja) ワクチン
EP3738978A1 (de) Rekombinanter gerinnungsfaktor viii mit verzögerter in-vivo-freisetzung und herstellungsverfahren dafür
KR970009354B1 (ko) 모티린형 폴리펩티드 및 그 용도