UA78805C2 - Acyloxypyrrolidine derivatives, method for their preparation and therapeutic use - Google Patents

Acyloxypyrrolidine derivatives, method for their preparation and therapeutic use Download PDF

Info

Publication number
UA78805C2
UA78805C2 UAA200500286A UA2005000286A UA78805C2 UA 78805 C2 UA78805 C2 UA 78805C2 UA A200500286 A UAA200500286 A UA A200500286A UA 2005000286 A UA2005000286 A UA 2005000286A UA 78805 C2 UA78805 C2 UA 78805C2
Authority
UA
Ukraine
Prior art keywords
compound
formula
dimethoxyphenyl
sulfonyl
dihydro
Prior art date
Application number
UAA200500286A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UA78805C2 publication Critical patent/UA78805C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/06—Antiabortive agents; Labour repressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Diabetes (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Urology & Nephrology (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Vascular Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Emergency Medicine (AREA)
  • Child & Adolescent Psychology (AREA)
  • Psychiatry (AREA)
  • Reproductive Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
UAA200500286A 2002-07-19 2003-07-17 Acyloxypyrrolidine derivatives, method for their preparation and therapeutic use UA78805C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0209242A FR2842527B1 (fr) 2002-07-19 2002-07-19 Derives d'acyloxypyrolidine, leur preparation et leur application en therapeutique
PCT/FR2003/002262 WO2004009585A2 (fr) 2002-07-19 2003-07-17 Derives d'acyloxypyrrolidine et leur utilisation en tant que ligands des recepteurs v1b et v1a de avp

Publications (1)

Publication Number Publication Date
UA78805C2 true UA78805C2 (en) 2007-04-25

Family

ID=29797610

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200500286A UA78805C2 (en) 2002-07-19 2003-07-17 Acyloxypyrrolidine derivatives, method for their preparation and therapeutic use

Country Status (27)

Country Link
US (1) US7202267B2 (pl)
EP (1) EP1525198B1 (pl)
JP (1) JP4264414B2 (pl)
CN (1) CN100425608C (pl)
AR (1) AR040571A1 (pl)
AT (1) ATE312092T1 (pl)
AU (1) AU2003271815B8 (pl)
BR (1) BR0312800A (pl)
CA (1) CA2492224A1 (pl)
DE (1) DE60302670T2 (pl)
DK (1) DK1525198T3 (pl)
EA (1) EA008444B1 (pl)
ES (1) ES2254962T3 (pl)
FR (1) FR2842527B1 (pl)
HR (1) HRP20041231A2 (pl)
IL (1) IL165942A (pl)
IS (1) IS2487B (pl)
ME (1) MEP12408A (pl)
MX (1) MXPA05000822A (pl)
NO (1) NO20050292L (pl)
NZ (1) NZ537615A (pl)
PL (1) PL375309A1 (pl)
RS (1) RS20050018A (pl)
TW (1) TWI274751B (pl)
UA (1) UA78805C2 (pl)
WO (1) WO2004009585A2 (pl)
ZA (1) ZA200500478B (pl)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1659121A4 (en) 2003-08-28 2008-11-26 Taisho Pharmaceutical Co Ltd 1,3-dihydro-2H-indol-2-one derivative
TW200643015A (en) 2005-03-11 2006-12-16 Akzo Nobel Nv 2-(4-oxo-4H-quinazolin-3-yl)acetamide derivatives
DE102005015957A1 (de) * 2005-03-31 2006-10-05 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
CA2610400A1 (en) 2005-06-07 2006-12-14 Pharmacopeia, Inc. Azinone and diazinone v3 inhibitors for depression and stress disorders
NZ575426A (en) 2006-09-11 2010-09-30 Organon Nv Quinazolinone and isoquinolinone acetamide derivatives useful for the treatment of disorders which are influenced by modulation of the activity of the hpa axis
CN103864658B (zh) * 2014-03-06 2016-06-15 南京工业大学 氮杂环丁酮衍生物及其制备方法与应用
CN104447489B (zh) * 2014-12-29 2017-01-11 南京工业大学 3,4-二芳基马来酰亚胺衍生物及其制备方法与应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2804114B1 (fr) * 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant

Also Published As

Publication number Publication date
IS7641A (is) 2005-01-12
AU2003271815A1 (en) 2004-02-09
IS2487B (is) 2008-12-15
RS20050018A (sr) 2007-06-04
NZ537615A (en) 2006-11-30
ES2254962T3 (es) 2006-06-16
ZA200500478B (en) 2006-07-26
CN100425608C (zh) 2008-10-15
IL165942A (en) 2010-04-15
AR040571A1 (es) 2005-04-13
EA008444B1 (ru) 2007-06-29
IL165942A0 (en) 2006-01-15
ATE312092T1 (de) 2005-12-15
FR2842527B1 (fr) 2005-01-28
MEP12408A (en) 2010-06-10
NO20050292L (no) 2005-04-19
EP1525198B1 (fr) 2005-12-07
DE60302670D1 (de) 2006-01-12
AU2003271815B8 (en) 2009-04-30
HK1074444A1 (en) 2005-11-11
MXPA05000822A (es) 2005-08-29
US20050192335A1 (en) 2005-09-01
BR0312800A (pt) 2005-04-19
US7202267B2 (en) 2007-04-10
EA200500032A1 (ru) 2005-08-25
TWI274751B (en) 2007-03-01
TW200410957A (en) 2004-07-01
FR2842527A1 (fr) 2004-01-23
PL375309A1 (pl) 2005-11-28
CN1681806A (zh) 2005-10-12
DE60302670T2 (de) 2006-09-07
JP4264414B2 (ja) 2009-05-20
CA2492224A1 (en) 2004-01-29
WO2004009585A3 (fr) 2004-05-06
WO2004009585A2 (fr) 2004-01-29
AU2003271815B2 (en) 2009-03-12
EP1525198A2 (fr) 2005-04-27
JP2005537271A (ja) 2005-12-08
HRP20041231A2 (en) 2005-02-28
DK1525198T3 (da) 2006-04-18

Similar Documents

Publication Publication Date Title
JP3992498B2 (ja) 新規1,3−ジヒドロ−2h−インドール−2−オン誘導体、それらの製造法およびそれらを含む医薬組成物
JP4861591B2 (ja) 新規な1,3−ジヒドロ−2h−インドール−2−オン誘導体、それらの製法およびそれらを含有する医薬組成物
US6596732B2 (en) 1,3-dihydro-2h-indol-2-one, preparation method and pharmaceutical compositions containing same
CN101184395A (zh) 包含二芳基胺的化合物和组合物及其作为类固醇激素核受体调节剂的用途
JP2016519674A (ja) 過剰増殖障害を治療または予防するための3−アセチルアミノ−1−(フェニル−ヘテロアリール−アミノカルボニルまたはフェニル−ヘテロアリール−カルボニルアミノ)ベンゼン誘導体
CN1964944A (zh) 作为抗病毒药的吲哚衍生物
JPH09509169A (ja) エストロゲンに関連する新生物及び病気の処置に有用な新規なインドール誘導体類
CN102666526A (zh) 作为ccr1受体拮抗剂的吲唑和吡唑并吡啶化合物
JPH0578350A (ja) ヒドラゾン誘導体、その製造方法及びその使用方法
KR20100126401A (ko) 신규한 3-아미노알킬-1,3-디히드로-2h-인돌-2-온 유도체, 그의 제법 및 그의 치료학적 용도
KR20100051812A (ko) 3-위치에서 이치환된 인돌-2-온 유도체, 그의 제조 및 그의 치료적 용도
JP2011518213A (ja) 1,3−ジヒドロ−2H−ピロロ[3,2−b]ピリジン−2−オン誘導体、この調製、およびこの治療用途
JP4264414B2 (ja) アシルオキシピロリジン、その製造法および治療における適用
WO2021129629A1 (zh) Zeste增强子同源物2抑制剂及其用途
MX2011008546A (es) Derivados de 3-benzofuranil-indol-2-ona-3-acetamidopiperazinas sustituidos, su preparacion y su uso en terapeutica.
KR20050019896A (ko) 아실옥시피롤리딘 유도체, 및 v1b 수용체 또는 v1b 및v1a 수용체 모두의 리간드로서의 그의 용도
JP2024525791A (ja) 治療に使用するためのイミダゾ[1,2-b][1,2,4]トリアゾール誘導体
HK1074444B (en) Acyloxypyrrolidine derivatives, preparation and therapeutic use thereof
TW201221127A (en) Sulfamide derivatives having NPY Y5 receptor antagonistic activity
HK1173729A (en) Indazole and pyrazolopyridine compounds as ccr1 receptor antagonists