UA80160C2 - Derivatives of [6,7-dihydro-5h-imidazo[1,2-?]imidazole-3-sulfonylamino]-propionamide - Google Patents

Derivatives of [6,7-dihydro-5h-imidazo[1,2-?]imidazole-3-sulfonylamino]-propionamide Download PDF

Info

Publication number: UA80160C2
Authority: UA; Ukraine
Prior art keywords: compound; formula; methyl; dihydro; imidazo
Prior art date: 2002-10-30

Application number

UAA200505014A

Other languages

English (en)

Ukrainian (uk)

Inventor

Terence Alfred Kelly

Jin Mi Kim

Rene Marc Lemieux

Original Assignee

Boehringer Ingelheim Pharma

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2002-10-30

Filing date

2003-10-27

Publication date

2007-08-27

2003-10-27 Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma

2007-08-27 Publication of UA80160C2 publication Critical patent/UA80160C2/uk

Links

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A61K31/4166—1,3-Diazoles having oxo groups directly attached to the heterocyclic ring, e.g. phenytoin
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/16—Central respiratory analeptics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Epidemiology (AREA)
Diabetes (AREA)
Immunology (AREA)
Cardiology (AREA)
Hematology (AREA)
Endocrinology (AREA)
Dermatology (AREA)
Pulmonology (AREA)
Heart & Thoracic Surgery (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Urology & Nephrology (AREA)
Obesity (AREA)
Neurology (AREA)
Biomedical Technology (AREA)
Pain & Pain Management (AREA)
Neurosurgery (AREA)
Oncology (AREA)
Transplantation (AREA)
Orthopedic Medicine & Surgery (AREA)
Physical Education & Sports Medicine (AREA)
Communicable Diseases (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)

UAA200505014A 2002-10-30 2003-10-27 Derivatives of [6,7-dihydro-5h-imidazo[1,2-?]imidazole-3-sulfonylamino]-propionamide UA80160C2 (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US42244602P	2002-10-30	2002-10-30
PCT/US2003/033865 WO2004041827A2 (en)	2002-10-30	2003-10-27	DERIVATIVES OF [6,7-DIHYDRO-5H-IMIDAZO[1,2-α] IMIDAZOLE-3-SULFONYLAMINO]-PROPIONAMIDE AND THEIR USE AS INHIBITORS UPON THE INTERACTION OF CAMS AND LEUKO INTEGRINS

Publications (1)

Publication Number	Publication Date
UA80160C2 true UA80160C2 (en)	2007-08-27

Family

ID=32312506

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
UAA200505014A UA80160C2 (en)	2002-10-30	2003-10-27	Derivatives of [6,7-dihydro-5h-imidazo[1,2-?]imidazole-3-sulfonylamino]-propionamide

Country Status (32)

Country	Link
US (4)	US6844360B2 (de)
EP (1)	EP1560830B1 (de)
JP (1)	JP4366477B2 (de)
KR (1)	KR20050067426A (de)
CN (1)	CN1708500A (de)
AR (1)	AR041854A1 (de)
AT (1)	ATE343582T1 (de)
AU (1)	AU2003284938A1 (de)
BR (1)	BR0315836A (de)
CA (1)	CA2504219A1 (de)
CO (1)	CO5690604A2 (de)
CY (1)	CY1106258T1 (de)
DE (1)	DE60309344T2 (de)
DK (1)	DK1560830T3 (de)
EA (1)	EA008443B1 (de)
EC (1)	ECSP055823A (de)
ES (1)	ES2276134T3 (de)
HR (1)	HRP20050387A2 (de)
MX (1)	MXPA05004480A (de)
MY (1)	MY136822A (de)
NO (1)	NO20052579L (de)
NZ (1)	NZ540269A (de)
PE (1)	PE20040782A1 (de)
PL (1)	PL375709A1 (de)
PT (1)	PT1560830E (de)
RS (1)	RS20050327A (de)
SI (1)	SI1560830T1 (de)
TW (1)	TW200424204A (de)
UA (1)	UA80160C2 (de)
UY (1)	UY28049A1 (de)
WO (1)	WO2004041827A2 (de)
ZA (1)	ZA200502701B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6492408B1 (en) *	1999-07-21	2002-12-10	Boehringer Ingelheim Pharmaceuticals, Inc.	Small molecules useful in the treatment of inflammatory disease
EP1712553A3 (de) *	2002-10-30	2006-11-02	Boehringer Ingelheim Pharmaceuticals, Inc.	Derivate von [6,7-dihydro-5h-imidazo[1,2-alpha]imidazol-3-sulfonylamino]-Propionamid und deren Verwendung als Inhibitoren der Interaktion von CAMS und Leukointegrinen
US6852748B1 (en) *	2002-10-30	2005-02-08	Boehringer Ingelheim Pharmaceuticals, Inc.	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide
US6844360B2 (en) *	2002-10-30	2005-01-18	Boehringer Ingelheim Pharmaceuticals, Inc.	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide
US8699508B2 (en) *	2003-12-18	2014-04-15	Intel Corporation	Response scheduling for multiple receivers
RU2007106927A (ru) *	2004-07-27	2008-09-10	БЕРИНГЕР ИНГЕЛЬХАЙМ ИНТЕРНАЦИОНАЛЬ ГмбХ (DE)	Синтез амидов 6,7,-дигидро-5н-имидазо [1.2-а] имидазол-3-сульфоновой кислоты
JP2008536834A (ja) *	2005-04-06	2008-09-11	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	［６，７−ジヒドロ−５Ｈイミダゾ［１，２−α］イミダゾール−３−スルホニル］−アゼテジン−カルボン酸、エステル及びアミドの誘導体及び抗炎症薬としてのそれらの使用
JP2008540648A (ja) *	2005-05-19	2008-11-20	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	６，７−ジヒドロ−５Ｈ−イミダゾ［１，２−ａ］イミダゾール−３−スルホン酸
JP2009525964A (ja) *	2006-01-20	2009-07-16	ベーリンガーインゲルハイムインターナショナルゲゼルシャフトミットベシュレンクテルハフツング	６，７−ジヒドロ−５Ｈ−イミダゾ［１，２−ａ］イミダゾール−３−スルホン酸アミドの合成
ES2525237T3 (es) *	2007-11-29	2014-12-19	Boehringer Ingelheim International Gmbh	Derivados de amidas del ácido 6,7-dihidro-5H-imidazo[1,2-a]imidazol-3-carboxílico
EP2445914B1 (de)	2009-06-02	2015-07-22	Boehringer Ingelheim International GmbH	DERIVATE VON 6,7-DIHYDRO-5H-IMIDAZO[1,2-a]IMIDAZOL-3-CARBONSÄUREAMIDEN
ES2446352T3 (es)	2009-06-02	2014-03-07	Boehringer Ingelheim International Gmbh	Derivados de amidas del ácido 6,7-dihidro-5H-imidazo[1,2-a]imidazol-3-carboxílico
WO2021217041A1 (en) *	2020-04-24	2021-10-28	Immvention Therapeutix	N-substituted alpha-amino and alpha-hydroxy carboxamide derivatives

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
EP0966447B1 (de)	1997-03-03	2003-03-05	Boehringer Ingelheim Pharmaceuticals Inc.	Kleine moleküle anwendbar in der behandlung von entzündgskrankheiten
US6355664B1 (en)	1997-03-03	2002-03-12	Boehringer Ingelheim Pharmaceuticals, Inc.	Phenylpyrrolidines, phenylimidazolidines, 3-phenyl-1,3-oxizolidines and 3-phenyl-1,3-thiazolidines and their use in the treatment of inflammatory disease
US6492408B1 (en) *	1999-07-21	2002-12-10	Boehringer Ingelheim Pharmaceuticals, Inc.	Small molecules useful in the treatment of inflammatory disease
US6414161B1 (en) *	2000-08-09	2002-07-02	Boehringer Ingelheim Pharmaceuticals, Inc.	Synthesis of (R)-3-(4-Bromobenzyl)-1-(3,5-dichlorophenyl)-5-iodo-3-methyl-1-H-imidazo[1,2-a]imidazol-2-one
US6844360B2 (en)	2002-10-30	2005-01-18	Boehringer Ingelheim Pharmaceuticals, Inc.	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonylamino]-propionamide
US6852748B1 (en) *	2002-10-30	2005-02-08	Boehringer Ingelheim Pharmaceuticals, Inc.	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide

2003
- 2003-10-15 US US10/686,073 patent/US6844360B2/en not_active Expired - Lifetime
- 2003-10-27 KR KR1020057007452A patent/KR20050067426A/ko not_active Withdrawn
- 2003-10-27 PT PT03779257T patent/PT1560830E/pt unknown
- 2003-10-27 DK DK03779257T patent/DK1560830T3/da active
- 2003-10-27 AU AU2003284938A patent/AU2003284938A1/en not_active Abandoned
- 2003-10-27 WO PCT/US2003/033865 patent/WO2004041827A2/en not_active Ceased
- 2003-10-27 ES ES03779257T patent/ES2276134T3/es not_active Expired - Lifetime
- 2003-10-27 SI SI200330574T patent/SI1560830T1/sl unknown
- 2003-10-27 NZ NZ540269A patent/NZ540269A/en unknown
- 2003-10-27 CA CA002504219A patent/CA2504219A1/en not_active Abandoned
- 2003-10-27 EA EA200500603A patent/EA008443B1/ru not_active IP Right Cessation
- 2003-10-27 DE DE60309344T patent/DE60309344T2/de not_active Expired - Fee Related
- 2003-10-27 HR HR20050387A patent/HRP20050387A2/xx not_active Application Discontinuation
- 2003-10-27 AT AT03779257T patent/ATE343582T1/de not_active IP Right Cessation
- 2003-10-27 PL PL03375709A patent/PL375709A1/xx not_active Application Discontinuation
- 2003-10-27 CN CNA2003801024910A patent/CN1708500A/zh active Pending
- 2003-10-27 EP EP03779257A patent/EP1560830B1/de not_active Expired - Lifetime
- 2003-10-27 BR BR0315836-5A patent/BR0315836A/pt not_active IP Right Cessation
- 2003-10-27 JP JP2004550109A patent/JP4366477B2/ja not_active Expired - Fee Related
- 2003-10-27 RS YUP-2005/0327A patent/RS20050327A/sr unknown
- 2003-10-27 UA UAA200505014A patent/UA80160C2/uk unknown
- 2003-10-27 MX MXPA05004480A patent/MXPA05004480A/es active IP Right Grant
- 2003-10-28 UY UY28049A patent/UY28049A1/es not_active Application Discontinuation
- 2003-10-28 TW TW092129932A patent/TW200424204A/zh unknown
- 2003-10-28 PE PE2003001088A patent/PE20040782A1/es not_active Application Discontinuation
- 2003-10-28 MY MYPI20034095A patent/MY136822A/en unknown
- 2003-10-29 AR ARP030103945A patent/AR041854A1/es unknown
2004
- 2004-10-20 US US10/969,105 patent/US7345074B2/en not_active Expired - Lifetime
2005
- 2005-01-13 US US11/034,701 patent/US7304067B2/en not_active Expired - Lifetime
- 2005-04-04 ZA ZA200502701A patent/ZA200502701B/en unknown
- 2005-05-26 CO CO05051551A patent/CO5690604A2/es not_active Application Discontinuation
- 2005-05-27 NO NO20052579A patent/NO20052579L/no not_active Application Discontinuation
- 2005-05-30 EC EC2005005823A patent/ECSP055823A/es unknown
2006
- 2006-11-09 CY CY20061101615T patent/CY1106258T1/el unknown
2007
- 2007-10-15 US US11/872,276 patent/US7589115B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
US7304067B2 (en)	2007-12-04
JP2006508947A (ja)	2006-03-16
PE20040782A1 (es)	2004-12-16
ZA200502701B (en)	2005-10-13
US7589115B2 (en)	2009-09-15
CY1106258T1 (el)	2011-06-08
WO2004041827A3 (en)	2004-07-15
AR041854A1 (es)	2005-06-01
HRP20050387A2 (en)	2006-10-31
US20050165027A1 (en)	2005-07-28
EP1560830B1 (de)	2006-10-25
DK1560830T3 (da)	2007-02-26
US6844360B2 (en)	2005-01-18
MXPA05004480A (es)	2005-07-26
ECSP055823A (es)	2005-08-11
NO20052579L (no)	2005-05-27
EA200500603A1 (ru)	2005-10-27
DE60309344D1 (de)	2006-12-07
EP1560830A2 (de)	2005-08-10
EA008443B1 (ru)	2007-06-29
DE60309344T2 (de)	2007-02-08
US7345074B2 (en)	2008-03-18
CN1708500A (zh)	2005-12-14
WO2004041827A2 (en)	2004-05-21
MY136822A (en)	2008-11-28
JP4366477B2 (ja)	2009-11-18
CA2504219A1 (en)	2004-05-21
RS20050327A (sr)	2007-06-04
ATE343582T1 (de)	2006-11-15
TW200424204A (en)	2004-11-16
US20040127534A1 (en)	2004-07-01
ES2276134T3 (es)	2007-06-16
SI1560830T1 (sl)	2007-02-28
PT1560830E (pt)	2007-01-31
BR0315836A (pt)	2005-09-13
PL375709A1 (en)	2005-12-12
KR20050067426A (ko)	2005-07-01
CO5690604A2 (es)	2006-10-31
US20080090819A1 (en)	2008-04-17
US20050054703A1 (en)	2005-03-10
UY28049A1 (es)	2004-05-31
NZ540269A (en)	2007-05-31
AU2003284938A1 (en)	2004-06-07

Publication	Publication Date	Title
US7589115B2 (en)	2009-09-15	Derivatives of [6,7-dihydro-5H-imidazo[1,2-α]imidazole-3-sulfonylamino]-propionamide
US7550494B2 (en)	2009-06-23	Small molecules useful in the treatment of inflammatory disease
US6852748B1 (en)	2005-02-08	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-pyrrolidine-2-carboxylic acid amide
US6353013B1 (en)	2002-03-05	Small molecules useful in the treatment of inflammatory disease
US20030008848A1 (en)	2003-01-09	Small molecules useful in the treatment of inflammatory disease
US7589114B2 (en)	2009-09-15	Derivatives of [6,7-dihydro-5H-imidazo[1,2-a]imidazole-3-sulfonyl]-azetidine-carboxylic acids, esters and amides
MX2007014392A (es)	2008-02-06	Derivados del acido 6, 7-dihidro-5h-imidazo [1,2-a] imidazol-3-sulfonico.
US20030232817A1 (en)	2003-12-18	Small molecules useful for the treatment of inflammatory disease
EP1712553A2 (de)	2006-10-18	Derivate von [6,7-dihydro-5h-imidazo[1,2-alpha]imidazol-3-sulfonylamino]-Propionamid und deren Verwendung als Inhibitoren der Interaktion von CAMS und Leukointegrinen