UA87822C2 - Производные нафтилена как ингибиторы цитохрома p450 - Google Patents
Производные нафтилена как ингибиторы цитохрома p450Info
- Publication number
- UA87822C2 UA87822C2 UAA200601312A UAA200601312A UA87822C2 UA 87822 C2 UA87822 C2 UA 87822C2 UA A200601312 A UAA200601312 A UA A200601312A UA A200601312 A UAA200601312 A UA A200601312A UA 87822 C2 UA87822 C2 UA 87822C2
- Authority
- UA
- Ukraine
- Prior art keywords
- cytochrome
- inhibitors
- treatment
- naphthylene
- derivatives
- Prior art date
Links
- 208000003311 Cytochrome P-450 Enzyme Inhibitors Diseases 0.000 title 1
- 125000004957 naphthylene group Chemical group 0.000 title 1
- 102100039282 Cytochrome P450 26A1 Human genes 0.000 abstract 1
- 101710130818 Cytochrome P450 26A1 Proteins 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- SHGAZHPCJJPHSC-YCNIQYBTSA-N all-trans-retinoic acid Chemical compound OC(=O)\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C SHGAZHPCJJPHSC-YCNIQYBTSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 229930002330 retinoic acid Natural products 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229960001727 tretinoin Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4164—1,3-Diazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/4192—1,2,3-Triazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/04—1,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US48638203P | 2003-07-10 | 2003-07-10 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UA87822C2 true UA87822C2 (ru) | 2009-08-25 |
Family
ID=34079229
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UAA200601312A UA87822C2 (ru) | 2003-07-10 | 2004-12-07 | Производные нафтилена как ингибиторы цитохрома p450 |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1654236A1 (ru) |
| JP (1) | JP4832295B2 (ru) |
| KR (1) | KR20060052799A (ru) |
| CN (1) | CN1819996B (ru) |
| AU (1) | AU2004257257B2 (ru) |
| BR (1) | BRPI0412424A (ru) |
| CA (1) | CA2532078A1 (ru) |
| IL (1) | IL172812A0 (ru) |
| IS (1) | IS8223A (ru) |
| MX (1) | MXPA06000401A (ru) |
| NO (1) | NO20060114L (ru) |
| RU (1) | RU2363696C2 (ru) |
| SG (1) | SG144941A1 (ru) |
| UA (1) | UA87822C2 (ru) |
| WO (1) | WO2005007631A1 (ru) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2550010A1 (en) | 2003-12-17 | 2005-06-30 | Allergan, Inc. | Methods for treating retinoid responsive disorders using selective inhibitors of cyp26a and cyp26b |
| US7662844B2 (en) | 2004-07-12 | 2010-02-16 | Osi Pharmaceuticals, Inc. | Naphthylene derivatives as cytochrome P450 inhibitors |
| EP2576544A4 (en) * | 2010-06-01 | 2013-09-11 | Angion Biomedica Corp | INHIBITORS OF CYTOCHROMES P450 AND USES THEREOF |
| US10414760B2 (en) | 2016-11-29 | 2019-09-17 | Angion Biomedica Corp. | Cytochrome P450 inhibitors and uses thereof |
| KR20180039185A (ko) * | 2010-11-13 | 2018-04-17 | 이노크린 파마슈티컬즈, 인크. | 금속효소 억제제 화합물 |
| EA201390876A1 (ru) * | 2010-12-13 | 2013-12-30 | Вайамет Фармасьютикалс, Инк. | Соединения, ингибирующие металлоферменты |
| CN102586187A (zh) * | 2012-02-23 | 2012-07-18 | 深圳市中美康士生物科技有限公司 | 一种中性粒细胞体外保存方法及培养基 |
| WO2014015137A2 (en) * | 2012-07-18 | 2014-01-23 | Angion Biomedica Corp. | Compositions and methods for treating dysproliferative diseases |
| EP3180335B1 (en) | 2014-08-11 | 2021-05-05 | Angion Biomedica Corporation | Cytochrome p450 inhibitors and uses thereof |
| CN104523967B (zh) * | 2014-12-12 | 2017-08-01 | 扬子江药业集团北京海燕药业有限公司 | 一种柏艾胶囊作为cyp酶抑制剂的应用 |
| CN107531631B (zh) | 2014-12-31 | 2021-09-03 | 安吉昂生物医药公司 | 用于治疗疾病的方法和药剂 |
| GB201602572D0 (en) * | 2016-02-12 | 2016-03-30 | Eriksson Leif And Strid Ake And Sirsjö Allan | New compound and uses |
| WO2018065288A1 (de) | 2016-10-07 | 2018-04-12 | Bayer Cropscience Aktiengesellschaft | 2-[2-phenyl-1-(sulfonylmethyl)vinyl]-imidazo[4,5-b]pyridin-derivate und verwandte verbindungen als schädlingsbekämpfungsmittel im pflanzenschutz |
| UY37556A (es) | 2017-01-10 | 2018-07-31 | Bayer Ag | Derivados heterocíclicos como pesticidas |
| AU2018208422B2 (en) | 2017-01-10 | 2021-11-11 | Bayer Aktiengesellschaft | Heterocyclene derivatives as pest control agents |
| WO2024223797A1 (en) | 2023-04-28 | 2024-10-31 | Institut National de la Santé et de la Recherche Médicale | Use of cyp3a4 inhibitors for the treatment of hepatitis d virus (hdv) infections |
| CN116903531B (zh) * | 2023-07-21 | 2025-12-12 | 上海中医药大学 | 细胞色素p450酶3a4的抑制剂及其制备方法与应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL291944A (ru) * | 1960-05-04 | |||
| NL131915C (ru) * | 1966-07-27 | |||
| DE3508903A1 (de) * | 1985-03-13 | 1986-09-18 | Hoechst Ag, 6230 Frankfurt | Neue 3-pyridylmethylnaphtylderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| DE3628545A1 (de) * | 1985-09-23 | 1987-04-23 | Hoechst Ag | Arylmethylazole und deren salze, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung |
| AU5285593A (en) * | 1992-10-21 | 1994-05-09 | Sankyo Company Limited | Azole compound |
| US6268363B1 (en) * | 1997-11-28 | 2001-07-31 | Lg Chemical Ltd. | Imidazole derivatives having an inhibitory activity for farnesyl transferase and process for preparation thereof |
| ATE293102T1 (de) * | 1998-04-23 | 2005-04-15 | Takeda Pharmaceutical | Naphthalene derivate ,ihre herstellung und verwendung |
| JP4546589B2 (ja) * | 1998-04-23 | 2010-09-15 | 武田薬品工業株式会社 | ナフタレン誘導体 |
| FR2796070B1 (fr) * | 1999-07-06 | 2003-02-21 | Lipha | Derives de benzodiazepines utilisables dans le traitement de dyslipidemies, de l'atherosclerose et du diabete, compositions pharmaceutiques les contenant et procedes de preparation |
| PE20010781A1 (es) * | 1999-10-22 | 2001-08-08 | Takeda Chemical Industries Ltd | Compuestos 1-(1h-imidazol-4-il)-1-(naftil-2-sustituido)etanol, su produccion y utilizacion |
| JP4520012B2 (ja) * | 1999-10-22 | 2010-08-04 | 武田薬品工業株式会社 | １−置換−１−（１ｈ−イミダゾール−４−イル）メタノール類 |
-
2004
- 2004-07-12 BR BRPI0412424-3A patent/BRPI0412424A/pt not_active IP Right Cessation
- 2004-07-12 CA CA002532078A patent/CA2532078A1/en not_active Abandoned
- 2004-07-12 CN CN200480019732XA patent/CN1819996B/zh not_active Expired - Fee Related
- 2004-07-12 AU AU2004257257A patent/AU2004257257B2/en not_active Expired - Fee Related
- 2004-07-12 WO PCT/US2004/022282 patent/WO2005007631A1/en not_active Ceased
- 2004-07-12 EP EP04756894A patent/EP1654236A1/en not_active Withdrawn
- 2004-07-12 KR KR1020067000669A patent/KR20060052799A/ko not_active Ceased
- 2004-07-12 SG SG200805435-5A patent/SG144941A1/en unknown
- 2004-07-12 JP JP2006518965A patent/JP4832295B2/ja not_active Expired - Fee Related
- 2004-07-12 RU RU2006103996/04A patent/RU2363696C2/ru not_active IP Right Cessation
- 2004-07-12 MX MXPA06000401A patent/MXPA06000401A/es active IP Right Grant
- 2004-12-07 UA UAA200601312A patent/UA87822C2/ru unknown
-
2005
- 2005-12-26 IL IL172812A patent/IL172812A0/en unknown
-
2006
- 2006-01-06 NO NO20060114A patent/NO20060114L/no not_active Application Discontinuation
- 2006-01-10 IS IS8223A patent/IS8223A/is unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU2004257257B2 (en) | 2011-05-12 |
| JP2007523866A (ja) | 2007-08-23 |
| JP4832295B2 (ja) | 2011-12-07 |
| EP1654236A1 (en) | 2006-05-10 |
| AU2004257257A1 (en) | 2005-01-27 |
| RU2363696C2 (ru) | 2009-08-10 |
| MXPA06000401A (es) | 2006-03-17 |
| NO20060114L (no) | 2006-02-09 |
| WO2005007631A1 (en) | 2005-01-27 |
| SG144941A1 (en) | 2008-08-28 |
| CN1819996A (zh) | 2006-08-16 |
| IS8223A (is) | 2006-01-10 |
| CA2532078A1 (en) | 2005-01-27 |
| RU2006103996A (ru) | 2006-07-10 |
| KR20060052799A (ko) | 2006-05-19 |
| BRPI0412424A (pt) | 2006-09-05 |
| IL172812A0 (en) | 2006-06-11 |
| CN1819996B (zh) | 2010-10-27 |
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