UA91029C2 - Спосіб отримання сумішей поліпептидів з використанням очищеної бромоводневої кислоти - Google Patents

Спосіб отримання сумішей поліпептидів з використанням очищеної бромоводневої кислоти

Info

Publication number
UA91029C2
UA91029C2 UAA200703838A UAA200703838A UA91029C2 UA 91029 C2 UA91029 C2 UA 91029C2 UA A200703838 A UAA200703838 A UA A200703838A UA A200703838 A UAA200703838 A UA A200703838A UA 91029 C2 UA91029 C2 UA 91029C2
Authority
UA
Ukraine
Prior art keywords
polypeptides
mixtures
preparation
hydrobromic acid
purified
Prior art date
Application number
UAA200703838A
Other languages
English (en)
Russian (ru)
Inventor
Бен-Зіон Долітзкі
Original Assignee
Тева Фармасьютікл Індастріз Лтд.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=36037047&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=UA91029(C2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Тева Фармасьютікл Індастріз Лтд. filed Critical Тева Фармасьютікл Індастріз Лтд.
Publication of UA91029C2 publication Critical patent/UA91029C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Rehabilitation Therapy (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Даний винахід належить до удосконаленого способу отримання суміші поліпептидів, що мають неоднорідні амінокислотні послідовності, де кожний поліпептид містить переважно аланін, глутамінову кислоту, тирозин та лізин, причому утворена суміш поліпептидів містить менш ніж 0,3 % бромованого тирозину та менш ніж 1000 ррm домішок іонів металів.
UAA200703838A 2004-09-09 2005-09-09 Спосіб отримання сумішей поліпептидів з використанням очищеної бромоводневої кислоти UA91029C2 (uk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US60884304P 2004-09-09 2004-09-09
PCT/US2005/032395 WO2006029393A2 (en) 2004-09-09 2005-09-09 Process for preparation of mixtures of polypeptides using purified hydrobromic acid

Publications (1)

Publication Number Publication Date
UA91029C2 true UA91029C2 (uk) 2010-06-25

Family

ID=36037047

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA200703838A UA91029C2 (uk) 2004-09-09 2005-09-09 Спосіб отримання сумішей поліпептидів з використанням очищеної бромоводневої кислоти

Country Status (27)

Country Link
US (2) US7495072B2 (uk)
EP (3) EP2361924B1 (uk)
JP (1) JP5149008B2 (uk)
KR (1) KR101317131B1 (uk)
CN (1) CN101166754B (uk)
AT (2) ATE536363T1 (uk)
AU (1) AU2005282249B2 (uk)
BR (1) BRPI0515033B1 (uk)
CA (1) CA2579656C (uk)
CY (1) CY1110280T1 (uk)
DE (1) DE602005018800D1 (uk)
DK (3) DK1799703T3 (uk)
ES (3) ES2451006T3 (uk)
HR (3) HRP20100164T1 (uk)
IL (2) IL181596A (uk)
IS (1) IS8622A (uk)
MX (1) MX2007002760A (uk)
NO (1) NO20071632L (uk)
NZ (1) NZ554018A (uk)
PL (3) PL1799703T3 (uk)
PT (3) PT2361924E (uk)
RS (3) RS53248B (uk)
RU (1) RU2388764C2 (uk)
SI (3) SI2177528T1 (uk)
UA (1) UA91029C2 (uk)
WO (1) WO2006029393A2 (uk)
ZA (1) ZA200702591B (uk)

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Publication number Publication date
WO2006029393A8 (en) 2007-04-19
DK1799703T3 (da) 2010-04-19
CA2579656A1 (en) 2006-03-16
IL241702A0 (en) 2015-11-30
CY1110280T1 (el) 2015-01-14
WO2006029393A2 (en) 2006-03-16
EP2361924A1 (en) 2011-08-31
SI2177528T1 (sl) 2012-04-30
EP2177528A1 (en) 2010-04-21
NO20071632L (no) 2007-06-05
HK1100780A1 (en) 2007-09-28
ZA200702591B (en) 2009-03-25
NZ554018A (en) 2009-06-26
ATE454396T1 (de) 2010-01-15
BRPI0515033B1 (pt) 2021-05-25
BRPI0515033A (pt) 2008-07-01
JP2008512494A (ja) 2008-04-24
HRP20140216T1 (hr) 2014-06-06
US20060052586A1 (en) 2006-03-09
HRP20100164T1 (hr) 2010-07-31
EP2361924B1 (en) 2013-12-11
CA2579656C (en) 2014-11-04
ES2382298T3 (es) 2012-06-07
DK2361924T3 (en) 2014-03-10
RU2007112956A (ru) 2008-10-20
AU2005282249A1 (en) 2006-03-16
HK1156637A1 (en) 2012-06-15
RS52265B (sr) 2012-10-31
CN101166754B (zh) 2014-04-23
US20070021324A1 (en) 2007-01-25
EP1799703A4 (en) 2008-09-03
SI2361924T1 (sl) 2014-04-30
HK1140775A1 (en) 2010-10-22
RU2388764C2 (ru) 2010-05-10
DK2177528T3 (da) 2012-03-26
PL1799703T3 (pl) 2010-06-30
PL2177528T3 (pl) 2012-09-28
BRPI0515033A8 (pt) 2019-01-22
KR101317131B1 (ko) 2013-10-10
EP1799703B1 (en) 2010-01-06
ES2451006T3 (es) 2014-03-26
PT2361924E (pt) 2014-03-13
PL2361924T3 (pl) 2014-08-29
ATE536363T1 (de) 2011-12-15
RS53248B (sr) 2014-08-29
AU2005282249B2 (en) 2012-08-02
ES2338138T3 (es) 2010-05-04
RS51257B (sr) 2010-12-31
KR20070059137A (ko) 2007-06-11
PT1799703E (pt) 2010-03-04
HRP20120209T1 (hr) 2012-06-30
US7495072B2 (en) 2009-02-24
IL181596A0 (en) 2007-07-04
MX2007002760A (es) 2007-05-18
JP5149008B2 (ja) 2013-02-20
SI1799703T1 (sl) 2010-04-30
DE602005018800D1 (de) 2010-02-25
EP1799703A2 (en) 2007-06-27
IL181596A (en) 2015-10-29
WO2006029393A3 (en) 2007-12-13
PT2177528E (pt) 2012-03-19
EP2177528B1 (en) 2011-12-07
IS8622A (is) 2007-03-16
CN101166754A (zh) 2008-04-23

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