UY33659A - Compuestos de furo[3,2-d]pirimidina - Google Patents

Compuestos de furo[3,2-d]pirimidina

Info

Publication number
UY33659A
UY33659A UY0001033659A UY33659A UY33659A UY 33659 A UY33659 A UY 33659A UY 0001033659 A UY0001033659 A UY 0001033659A UY 33659 A UY33659 A UY 33659A UY 33659 A UY33659 A UY 33659A
Authority
UY
Uruguay
Prior art keywords
compounds
furo
pyrimidine
diseases
useful
Prior art date
Application number
UY0001033659A
Other languages
English (en)
Inventor
Vasudevan Anil
Li Bin
Kelly D Mullen
David J Calderwood
Noel S Wilson
Cox Philip
Michael Z Hoemann
Bruce Clapham
Clara I Villamil
Somal Gagandeep
Original Assignee
Abbott Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Lab filed Critical Abbott Lab
Publication of UY33659A publication Critical patent/UY33659A/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C07D491/044—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C07D491/048—Ortho-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring the oxygen-containing ring being five-membered
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
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    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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Abstract

Compuestos novedosos de fórmula (I), sales, metabolitos con actividad biológica, prodrogas, racematos, enantiómeros, diastereómeros, solvatos e hidratos farmacéuticamente aceptables de éstos, donde las variables son como se las define en la presente . Los compuestos de fórmula (I) son útiles como inhibidores de quinasas, por lo que han de resultar de utilidad para tratar determinadas afecciones y enfermedades, especialmente afecciones y enfermedades inflamatorias y afecciones y trastornos proli ferativos, por ejemplo, cánceres.
UY0001033659A 2010-10-08 2011-10-07 Compuestos de furo[3,2-d]pirimidina UY33659A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US39115710P 2010-10-08 2010-10-08
US201161503368P 2011-06-30 2011-06-30

Publications (1)

Publication Number Publication Date
UY33659A true UY33659A (es) 2012-04-30

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ID=45928140

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Application Number Title Priority Date Filing Date
UY0001033659A UY33659A (es) 2010-10-08 2011-10-07 Compuestos de furo[3,2-d]pirimidina

Country Status (23)

Country Link
US (1) US8551981B2 (es)
EP (1) EP2624698A4 (es)
JP (1) JP2013539762A (es)
KR (1) KR20140005882A (es)
CN (1) CN103442568A (es)
AR (1) AR083358A1 (es)
AU (1) AU2011311867A1 (es)
BR (1) BR112013008240A2 (es)
CA (1) CA2813437A1 (es)
CL (1) CL2013000933A1 (es)
CO (1) CO6731080A2 (es)
CR (1) CR20130206A (es)
EC (1) ECSP13012554A (es)
GT (1) GT201300091A (es)
IL (1) IL225622A0 (es)
MX (1) MX2013003913A (es)
PE (1) PE20140245A1 (es)
PH (1) PH12013500661A1 (es)
RU (1) RU2013120966A (es)
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