WO1996013213A3 - Ultraschallverfahren und schaltungen zur durchführung dieser verfahren - Google Patents

Ultraschallverfahren und schaltungen zur durchführung dieser verfahren Download PDF

Info

Publication number
WO1996013213A3
WO1996013213A3 PCT/EP1995/004050 EP9504050W WO9613213A3 WO 1996013213 A3 WO1996013213 A3 WO 1996013213A3 EP 9504050 W EP9504050 W EP 9504050W WO 9613213 A3 WO9613213 A3 WO 9613213A3
Authority
WO
WIPO (PCT)
Prior art keywords
carrying
ultrasonic
area under
under investigation
circuits
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP1995/004050
Other languages
English (en)
French (fr)
Other versions
WO1996013213A2 (de
Inventor
Volkmar Uhlendorf
Christian Hoffmann
Thomas Fritzsch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Pharma AG
Original Assignee
Schering AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering AG filed Critical Schering AG
Priority to CA002204161A priority Critical patent/CA2204161C/en
Priority to AU38424/95A priority patent/AU698398B2/en
Priority to EP95936497A priority patent/EP0789536A2/de
Priority to NZ295149A priority patent/NZ295149A/xx
Priority to JP8514280A priority patent/JPH10507672A/ja
Priority to MXPA/A/1997/002842A priority patent/MXPA97002842A/xx
Publication of WO1996013213A2 publication Critical patent/WO1996013213A2/de
Publication of WO1996013213A3 publication Critical patent/WO1996013213A3/de
Priority to NO19972029A priority patent/NO325566B1/no
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
    • A61B8/48—Diagnostic techniques
    • A61B8/481—Diagnostic techniques involving the use of contrast agents, e.g. microbubbles introduced into the bloodstream
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01S—RADIO DIRECTION-FINDING; RADIO NAVIGATION; DETERMINING DISTANCE OR VELOCITY BY USE OF RADIO WAVES; LOCATING OR PRESENCE-DETECTING BY USE OF THE REFLECTION OR RERADIATION OF RADIO WAVES; ANALOGOUS ARRANGEMENTS USING OTHER WAVES
    • G01S7/00—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00
    • G01S7/52—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00
    • G01S7/52017—Details of systems according to groups G01S13/00, G01S15/00, G01S17/00 of systems according to group G01S15/00 particularly adapted to short-range imaging
    • G01S7/52023—Details of receivers
    • G01S7/52036—Details of receivers using analysis of echo signal for target characterisation
    • G01S7/52038—Details of receivers using analysis of echo signal for target characterisation involving non-linear properties of the propagation medium or of the reflective target

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Surgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Nonlinear Science (AREA)
  • Computer Networks & Wireless Communication (AREA)
  • Hematology (AREA)
  • General Physics & Mathematics (AREA)
  • Remote Sensing (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Investigating Or Analyzing Materials By The Use Of Ultrasonic Waves (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Measurement Of Velocity Or Position Using Acoustic Or Ultrasonic Waves (AREA)

Abstract

Es wird ein Verfahren für die selektive grafische Wiedergabe und/oder für die Auswertung des Dopplerspektrums von Objekten, die Schallintensitäten einen begrenzten Widerstand entgegensetzen, z.B. von biologischen Organen und Gewebe, mit Hilfe eines Ultraschallverfahrens durchgeführt, bei dem ein Material in den Untersuchungsbereich, der akustisch zu bestrahlen ist, eingeführt wird, worauf in diesem Untersuchungsbereich nichtlineare Schwingungen durch eingestrahlte Ultraschallwellen erzeugt werden, und das Signal durch einen Ultraschallwandler ausgewertet wird. Es wird auch eine Schaltung zur Durchführung dieses Verfahrens beschrieben.
PCT/EP1995/004050 1994-11-01 1995-10-13 Ultraschallverfahren und schaltungen zur durchführung dieser verfahren Ceased WO1996013213A2 (de)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA002204161A CA2204161C (en) 1994-11-01 1995-10-13 Ultrasonic processes and circuits for carrying out those processes
AU38424/95A AU698398B2 (en) 1994-11-01 1995-10-13 Ultrasonic processes and circuits for carrying out those processes
EP95936497A EP0789536A2 (de) 1994-11-01 1995-10-13 Ultraschallverfahren und schaltungen zur durchführung dieser verfahren
NZ295149A NZ295149A (en) 1994-11-01 1995-10-13 Ultrasonic scanning, eg of organs or tissue, by generation of non-linear vibrations in introduced microbubbles irradiated with hf ultrasonic energy
JP8514280A JPH10507672A (ja) 1994-11-01 1995-10-13 超音波の方法、および、該方法を実行するための回路
MXPA/A/1997/002842A MXPA97002842A (en) 1994-11-01 1995-10-13 Ultrasonic procedures and circuits to carry out such procedures
NO19972029A NO325566B1 (no) 1994-11-01 1997-04-30 Objektavbildning ved hjelp av ultralyd

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/332,746 1994-11-01
US08/332,746 US5678553A (en) 1994-11-01 1994-11-01 Ultrasonic processes and circuits for carrying out those processes

Publications (2)

Publication Number Publication Date
WO1996013213A2 WO1996013213A2 (de) 1996-05-09
WO1996013213A3 true WO1996013213A3 (de) 1996-08-01

Family

ID=23299688

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1995/004050 Ceased WO1996013213A2 (de) 1994-11-01 1995-10-13 Ultraschallverfahren und schaltungen zur durchführung dieser verfahren

Country Status (13)

Country Link
US (1) US5678553A (de)
EP (1) EP0789536A2 (de)
JP (3) JPH10507672A (de)
KR (1) KR100380126B1 (de)
CN (1) CN1154436C (de)
AU (1) AU698398B2 (de)
CA (2) CA2666047C (de)
IL (1) IL115832A (de)
NO (2) NO325566B1 (de)
NZ (1) NZ295149A (de)
TW (1) TW318140B (de)
WO (1) WO1996013213A2 (de)
ZA (1) ZA959217B (de)

Families Citing this family (47)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3829999A1 (de) 1988-09-01 1990-03-15 Schering Ag Ultraschallverfahren und schaltungen zu deren durchfuehrung
US5540909A (en) * 1994-09-28 1996-07-30 Alliance Pharmaceutical Corp. Harmonic ultrasound imaging with microbubbles
USRE38971E1 (en) * 1995-01-31 2006-02-07 Kabushiki Kaisha Toshiba Ultrasound diagnostic apparatus and method
US5608690A (en) * 1995-03-02 1997-03-04 Acuson Corporation Transmit beamformer with frequency dependent focus
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US7104956B1 (en) 1996-11-08 2006-09-12 Research Corporation Technologies, Inc. Finite amplitude distortion-based inhomogeneous pulse echo ultrasonic imaging
GB9701274D0 (en) * 1997-01-22 1997-03-12 Andaris Ltd Ultrasound contrast imaging
GB9708246D0 (en) * 1997-04-24 1997-06-18 Nycomed Imaging As Improvements in or relating to ultrasound imaging
US6050944A (en) * 1997-06-17 2000-04-18 Acuson Corporation Method and apparatus for frequency control of an ultrasound system
FR2772590B1 (fr) * 1997-12-18 2000-04-14 Michel Puech Utilisation d'un transducteur ultrasonore pour l'exploration echographique du segment posterieur du globe oculaire
GB9800813D0 (en) 1998-01-16 1998-03-11 Andaris Ltd Improved ultrasound contrast imaging method and apparatus
US6117082A (en) * 1999-03-31 2000-09-12 Acuson Corporation Medical diagnostic ultrasound imaging system and method with fractional harmonic seed signal
US6231512B1 (en) * 1999-05-28 2001-05-15 General Electric Company Method and apparatus for parametric harmonic imaging
US6514209B1 (en) * 1999-06-07 2003-02-04 Drexel University Method of enhancing ultrasonic techniques via measurement of ultraharmonic signals
JP4768914B2 (ja) * 2000-12-26 2011-09-07 株式会社東芝 超音波診断装置
US6547738B2 (en) 2001-05-03 2003-04-15 Ge Medical Systems Global Technology Company, Llc Methods and apparatus for using ultrasound with contrast agent
US6951542B2 (en) 2002-06-26 2005-10-04 Esaote S.P.A. Method and apparatus for ultrasound imaging of a biopsy needle or the like during an ultrasound imaging examination
JP3844667B2 (ja) * 2001-07-23 2006-11-15 ジーイー・メディカル・システムズ・グローバル・テクノロジー・カンパニー・エルエルシー 超音波診断装置
US6638230B2 (en) 2001-07-31 2003-10-28 Koninklijke Philips Electronics N.V. Apparatus and method of frequency compounding to perform contrast imaging
US6537217B1 (en) * 2001-08-24 2003-03-25 Ge Medical Systems Global Technology Company, Llc Method and apparatus for improved spatial and temporal resolution in ultrasound imaging
US6699191B2 (en) * 2002-06-18 2004-03-02 Koninklijke Philips Electronics N.V. Ultrasound device to detect Caisson's disease
US6953434B2 (en) * 2002-09-24 2005-10-11 Ge Medical Systems Global Technology Company, Llc Method and apparatus to enhance ultrasound contrast imaging using stepped-chirp waveforms
US6783496B2 (en) 2002-11-01 2004-08-31 Ge Medical Systems Global Technology Company, Llc Method and apparatus for improving contrast-to-tissue ratio in ultrasound contrast imaging with subharmonic imaging
ITFI20030077A1 (it) * 2003-03-26 2004-09-27 Actis Active Sensors S R L Metodo per l'indagine ecografica tramite mezzi di contrasto
US6960169B2 (en) 2003-05-19 2005-11-01 Siemens Medical Solutions Usa, Inc. Spread spectrum coding for ultrasound contrast agent imaging
EP1515158B1 (de) * 2003-09-09 2013-07-17 Esaote S.p.A. Ultraschall-Bilderzeugungsverfahren mit Kontrastmittel-Anwesenheit in dem Aufnahmeobjekt
ITFI20030254A1 (it) * 2003-10-08 2005-04-09 Actis Active Sensors S R L Metodo e dispositivo perfezionati per l'analisi spettrale
EP1713400B1 (de) * 2004-01-16 2012-12-26 Boston Scientific Scimed, Inc. Gerät für die medizinische bilddarstellung
ATE466596T1 (de) * 2004-01-20 2010-05-15 Sunnybrook & Womens College Hochfrequenz-ultraschall-darstellung mit kontrastmitteln
JP4583068B2 (ja) * 2004-05-11 2010-11-17 株式会社東芝 超音波診断装置
EP1791471A1 (de) * 2004-09-13 2007-06-06 Koninklijke Philips Electronics N.V. Verfahren und vorrichtung zur messung und/oder bestimmung des fliessverhaltens einer körperflüssigkeit mittels ultraschall
CN100581483C (zh) * 2004-09-28 2010-01-20 皇家飞利浦电子股份有限公司 用于呈现关于由超声外部测量的体液的流动特性的信息的方法和装置
JP5038289B2 (ja) * 2005-03-11 2012-10-03 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 位相収差訂正のためのマイクロバブル生成技術
EP1933944A2 (de) * 2005-08-30 2008-06-25 Koninklijke Philips Electronics N.V. Verfahren zur verwendung eines kombinierten bildgebenden und heilenden wandlers zur auflösung von blutgerinnseln
US7967753B2 (en) 2006-08-01 2011-06-28 Stichting Voor de Technische Wetenschappen of Van Vollenhovenlaan Pulse inversion sequences for nonlinear imaging
CN100495020C (zh) * 2006-08-03 2009-06-03 长安大学 多通道混凝土超声信号处理装置
WO2008062342A2 (en) * 2006-11-20 2008-05-29 Koninklijke Philips Electronics, N.V. Control and display of ultrasonic microbubble cavitation
KR100818669B1 (ko) * 2007-03-09 2008-04-02 한국과학기술원 하지 관류정도 측정장치
WO2008144452A1 (en) * 2007-05-16 2008-11-27 Verathon Inc. System and method for ultrasonic harmonic imaging
GB0818775D0 (en) 2008-10-13 2008-11-19 Isis Innovation Investigation of physical properties of an object
US9642596B2 (en) 2011-04-20 2017-05-09 Hitachi, Ltd. Ultrasound imaging apparatus
KR20130051226A (ko) * 2011-11-09 2013-05-20 주식회사 퍼시픽시스템 안구 약물 전달 시스템 및 이에 사용되는 미소 기포의 제조 방법
KR101389243B1 (ko) * 2012-03-06 2014-04-24 제주대학교 산학협력단 비침습적 초음파 방광내압 측정시스템 및 그 방법
WO2014007100A1 (ja) 2012-07-05 2014-01-09 日立アロカメディカル株式会社 超音波診断装置および超音波画像取得方法
KR102295378B1 (ko) 2017-06-16 2021-08-31 지멘스 메디컬 솔루션즈 유에스에이, 인크. 초음파 프로브의 초음파 신호 형성 방법 및 초음파 시스템
CN111415408B (zh) * 2020-04-14 2022-06-07 西安交通大学 一种超声空化的微秒级多尺度时空成像及特征图谱计算方法与系统
AU2022309310A1 (en) 2021-07-13 2024-01-25 The University Of Western Ontario Lymph node locating device

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3803972A1 (de) * 1988-02-05 1989-08-10 Schering Ag Ultraschallkontrastmittel
EP0357164A1 (de) * 1988-09-01 1990-03-07 Schering Aktiengesellschaft Ultraschallverfahren und Schaltungen zu deren Durchführung
WO1991015999A1 (en) * 1990-04-26 1991-10-31 The Victoria University Of Manchester Ultrasound imaging technique using non linear scattering from bubbles

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3640271A (en) * 1969-06-30 1972-02-08 Ibm Blood flow pressure measurement technique employing injected bubbled and ultrasonic frequency scanning
JPS57179745A (en) * 1981-04-30 1982-11-05 Fujitsu Ltd Method and device for measuring material property by ultrasonic wave
JPS5826238A (ja) * 1981-08-08 1983-02-16 Fujitsu Ltd 超音波による圧力測定方式
US4532812A (en) * 1983-06-30 1985-08-06 Nl Industries, Inc. Parametric acoustic flow meter
US4610255A (en) * 1983-12-02 1986-09-09 Fujitsu Limited Ultrasonic non-linear parameter measuring system
DE3637926C1 (de) * 1986-11-05 1987-11-26 Schering Ag Ultraschall-Manometrieverfahren in einer Fluessigkeit mittels Mikroblaeschen
US5425366A (en) * 1988-02-05 1995-06-20 Schering Aktiengesellschaft Ultrasonic contrast agents for color Doppler imaging
US5410516A (en) * 1988-09-01 1995-04-25 Schering Aktiengesellschaft Ultrasonic processes and circuits for performing them
US5255683A (en) * 1991-12-30 1993-10-26 Sound Science Limited Partnership Methods of and systems for examining tissue perfusion using ultrasonic contrast agents
US5567415A (en) * 1993-05-12 1996-10-22 The Board Of Regents Of The University Of Nebraska Ultrasound contrast agents and methods for their manufacture and use
US5526816A (en) * 1994-09-22 1996-06-18 Bracco Research S.A. Ultrasonic spectral contrast imaging
US5456257A (en) * 1994-11-23 1995-10-10 Advanced Technology Laboratories, Inc. Ultrasonic detection of contrast agents
US5560364A (en) * 1995-05-12 1996-10-01 The Board Of Regents Of The University Of Nebraska Suspended ultra-sound induced microbubble cavitation imaging
US5577505A (en) * 1996-02-06 1996-11-26 Hewlett-Packard Company Means for increasing sensitivity in non-linear ultrasound imaging systems

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3803972A1 (de) * 1988-02-05 1989-08-10 Schering Ag Ultraschallkontrastmittel
EP0357164A1 (de) * 1988-09-01 1990-03-07 Schering Aktiengesellschaft Ultraschallverfahren und Schaltungen zu deren Durchführung
WO1991015999A1 (en) * 1990-04-26 1991-10-31 The Victoria University Of Manchester Ultrasound imaging technique using non linear scattering from bubbles

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
SIEGERT ET AL.: "Application of a resonance method for measuring the size of bubbles in an echocontrast agent", PROCEEDINGS OF THE NINTH ANNUAL CONFERENCE OF THE IEEE ENGINEERING IN MEDICINE AND BIOLOGY SOCIETY, vol. 2, US, pages 691 - 692, XP000568223 *

Also Published As

Publication number Publication date
CN1162250A (zh) 1997-10-15
CN1154436C (zh) 2004-06-23
NO972029D0 (no) 1997-04-30
CA2666047C (en) 2011-02-22
AU3842495A (en) 1996-05-23
IL115832A0 (en) 1996-01-19
NO328331B1 (no) 2010-02-01
AU698398B2 (en) 1998-10-29
JP2009119299A (ja) 2009-06-04
NZ295149A (en) 1998-10-28
MX9702842A (es) 1997-07-31
NO325566B1 (no) 2008-06-23
CA2204161A1 (en) 1996-05-09
KR100380126B1 (ko) 2003-08-02
WO1996013213A2 (de) 1996-05-09
JP2007283119A (ja) 2007-11-01
EP0789536A2 (de) 1997-08-20
NO20072892L (no) 1997-04-30
JPH10507672A (ja) 1998-07-28
CA2666047A1 (en) 1996-05-09
US5678553A (en) 1997-10-21
TW318140B (de) 1997-10-21
KR970706759A (ko) 1997-12-01
CA2204161C (en) 2009-09-29
IL115832A (en) 1998-12-06
NO972029L (no) 1997-04-30
ZA959217B (en) 1996-05-27

Similar Documents

Publication Publication Date Title
WO1996013213A3 (de) Ultraschallverfahren und schaltungen zur durchführung dieser verfahren
CA1338175C (en) Ultrasound process and circuits for carrying out same
JP3604696B2 (ja) 超音波スペクトルのコントラスト映像化
IL93232A (en) Process and device for localization of acoustic waves
EP0629993A3 (de) Anpassungsschicht zum Anpassen du akustischen Impedanz von klinischen Ultraschallwandler.
EP0548048A1 (de) Gerät zur Stosswellen-Behandlung
GB2287789B (en) An acoustic transducer and methods of beam steering and focusing
ATE223137T1 (de) Akustische vorrichtung mit biegewellenmoden
DE69738998D1 (de) Photoakustische mamma-abtastvorrichtung
EP0313828A3 (de) Schalldämpfer
JPS56137263A (en) Ultrasonic echo sounding probe having acoustic lens and echo sounder using it
AU2002212409A1 (en) Method and non-invasive device for focusing acoustic waves
AU9133598A (en) Ultrasonic transmit pulses for nonlienar ultrasonic imaging
Ricci et al. A programmable real-time system for development and test of new ultrasound investigation methods
SE9001340D0 (sv) Ultrasound method and apparatus foer examining dense tissues in particular
ATE356403T1 (de) Ultraschalldiagnose-abbildungssystem mit dynamischer mikrostrahlformung
WO1999040847A3 (en) Multi-frequency ultrasonic imaging and therapy
Van der Steen et al. Harmonic imaging at high frequencies for IVUS
JP2828259B2 (ja) 魚群探知機
JPS6340974Y2 (de)
CA2515666A1 (en) Ultrasonic processes and circuits for carrying out those processes
JPS5471666A (en) Electronic watch
JP2006528522A (ja) 音波撮像の方法および装置
WO2005071437A1 (en) Contrast dual frequency imaging
JP2742207B2 (ja) 超音波振動子

Legal Events

Date Code Title Description
WWE Wipo information: entry into national phase

Ref document number: PA/a/1997/002842

Country of ref document: MX

Ref document number: 95195991.3

Country of ref document: CN

AK Designated states

Kind code of ref document: A2

Designated state(s): AU CA CN JP KR MX NO NZ

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
AK Designated states

Kind code of ref document: A3

Designated state(s): AU CA CN JP KR MX NO NZ

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH DE DK ES FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1995936497

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 295149

Country of ref document: NZ

ENP Entry into the national phase

Ref document number: 2204161

Country of ref document: CA

Ref document number: 2204161

Country of ref document: CA

Kind code of ref document: A

WWE Wipo information: entry into national phase

Ref document number: 1019970702870

Country of ref document: KR

WWP Wipo information: published in national office

Ref document number: 1995936497

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1019970702870

Country of ref document: KR

WWR Wipo information: refused in national office

Ref document number: 1995936497

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1995936497

Country of ref document: EP

WWG Wipo information: grant in national office

Ref document number: 1019970702870

Country of ref document: KR