WO2003018038A2 - Composition pour le traitement de varices - Google Patents

Composition pour le traitement de varices

Info

Publication number
WO2003018038A2
WO2003018038A2 PCT/ZA2002/000074 ZA0200074W WO03018038A2 WO 2003018038 A2 WO2003018038 A2 WO 2003018038A2 ZA 0200074 W ZA0200074 W ZA 0200074W WO 03018038 A2 WO03018038 A2 WO 03018038A2
Authority
WO
WIPO (PCT)
Prior art keywords
percentage
weight
oil
topical medical
medical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/ZA2002/000074
Other languages
English (en)
Other versions
WO2003018038A3 (fr
Inventor
Stephen James Rademeyer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to AU2002351419A priority Critical patent/AU2002351419A1/en
Publication of WO2003018038A2 publication Critical patent/WO2003018038A2/fr
Anticipated expiration legal-status Critical
Publication of WO2003018038A3 publication Critical patent/WO2003018038A3/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers

Definitions

  • This invention relates to the field of topical medical compositions.
  • the invention specifically relates to topical preparations for the treatment of fine varicose, telangiectatic and spider talangiectatic veins.
  • the invention also relates to preparations having in their composition ethylene diamine tetra acetic acid disodium salt.
  • Varicose and telangietatic veins are superficial distended blood vessels that are usually found on the lower limbs, but can be located anywhere on the body.
  • the venous drainage of the lower limb can be compartmentalized into a deep and superficial system.
  • the superficial system communicates with the deep system by means of perforators along the entire length of the lower limb.
  • An underlying incompetent non-return valve system of the deep venous system of the leg leads to an accumulation of blood, and the subsequent shunting of the blood into the superficial venous system.
  • the functioning of the valves in the deep venous system is affected by conditions such as pregnancy, obesity, a genetic predisposition, deep venous thrombosis and a variety of other conditions. These dysfunctional valves then lead to a diminished return of the de-oxygenated blood from the lower limbs, back to the heart and lungs.
  • a topical medical composition which includes oil of Tea-tree, oil of Sage, oil of Rosemary; ethylene diamine tetra acetic acid disodium salt and a base mixture.
  • the base mixture may include emulsifying wax, white soft paraffin, liquid paraffin, purified water and chlorocresol.
  • the percentage by weight of the oil of Rosemary may be from about 0.1 - 1%
  • the percentage by weight of the oil of Sage may be from about 0.1 - 1%
  • the percentage by weight of the oil of Tea-tree may be from about 0.1 - 1%
  • the percentage by weight of ethylene diamine tetra acetic acid disodium salt may be from about 0.1 - 3%
  • the percentage by weight of emulsifying wax can be about 9%, the percentage by weight of white soft paraffin can be about 15%, the percentage by weight of liquid paraffin can be about 6%, the percentage by weight of purified water can be about 70% and wherein the percentage by weight of chlorocresol can be about 0.1%
  • the topical medical composition may be in the form of a cream.
  • the percentage by weight of the oil of Rosemary is 0.125%
  • the percentage by weight of the oil of Sage is 0.125%
  • the percentage by weight of the oil of Tea-tree is 0.125%
  • the percentage by weight of ethylene diamine tetra acetic acid disodium salt is 1%.
  • the percentage by weight of emulsifying wax is 9%
  • the percentage by weight of white soft paraffin is 15%
  • the percentage by weight of liquid paraffin is 6%
  • the percentage by weight of purified water is 70%
  • the percentage by weight of chlorocresol is 0.1%.
  • topical medical composition may be in the form of a
  • the topical medical composition may be in the form of an oil.
  • a topical medical preparation in the form of a cream, in accordance with the invention is prepared by, and has the following composition:
  • Oil of tea-tree 1.25ml is mixed together.
  • mixture B 300 Grams of mixture B is gently heated and 1 gram of chlorocresol dissolved in water added and then the remaining 699 grams of purified water is added. The mixture is stirred until room temperature is reached.
  • the final product is then made by adding mixture A to mixture C, and stirring until homogenously mixed.

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Biotechnology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

L'invention concerne une composition médicale topique qui renferme de l'huile d'arbre à thé, de l'huile de sauge, de l'huile de romarin, du sel disodique de l'acide éthylènediaminetétracétique, et un mélange de base comprenant de la cire émulsifiante, de la paraffine molle blanche, de la paraffine liquide, de l'eau purifiée et du chlorocrésol.
PCT/ZA2002/000074 2001-05-14 2002-05-10 Composition pour le traitement de varices Ceased WO2003018038A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2002351419A AU2002351419A1 (en) 2001-05-14 2002-05-10 Composition for the treatment of varicose veins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ZA2000/6587 2001-05-14
ZA200106587 2001-05-14

Publications (2)

Publication Number Publication Date
WO2003018038A2 true WO2003018038A2 (fr) 2003-03-06
WO2003018038A3 WO2003018038A3 (fr) 2003-11-27

Family

ID=25589266

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/ZA2002/000074 Ceased WO2003018038A2 (fr) 2001-05-14 2002-05-10 Composition pour le traitement de varices

Country Status (2)

Country Link
AU (1) AU2002351419A1 (fr)
WO (1) WO2003018038A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2359690C1 (ru) * 2008-01-23 2009-06-27 Открытое Акционерное Общество Завод Экологической Техники И Экопитания "Диод" Средство для ухода за ногами при хронической венозной недостаточности нижних конечностей

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2556969B1 (fr) * 1983-12-27 1986-04-25 Oreal Composition cosmetique ou pharmaceutique a base d'extraits vegetaux ayant une action sur la fragilite capillaire
US5989558A (en) * 1997-12-05 1999-11-23 Lopes; Carlos Alberto Correia Method of using rosmarinus officinalis for treating various diseases

Also Published As

Publication number Publication date
AU2002351419A1 (en) 2003-03-10
WO2003018038A3 (fr) 2003-11-27

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