WO2006100413A3 - Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique - Google Patents

Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique Download PDF

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Publication number
WO2006100413A3
WO2006100413A3 PCT/FR2006/050259 FR2006050259W WO2006100413A3 WO 2006100413 A3 WO2006100413 A3 WO 2006100413A3 FR 2006050259 W FR2006050259 W FR 2006050259W WO 2006100413 A3 WO2006100413 A3 WO 2006100413A3
Authority
WO
WIPO (PCT)
Prior art keywords
thioxylose
novel compounds
compounds derived
therapeutic use
thioxylopyranose
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/FR2006/050259
Other languages
English (en)
Other versions
WO2006100413A2 (fr
WO2006100413A9 (fr
Inventor
Veronique Barberousse
Michel Bondoux
Didier Thomas
Vincent Peyrou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratories Fournier SAS
Original Assignee
Laboratories Fournier SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to CA002602698A priority Critical patent/CA2602698A1/fr
Priority to US11/909,489 priority patent/US8148407B2/en
Priority to EP06726275A priority patent/EP1861411A2/fr
Priority to KR1020077021135A priority patent/KR101336547B1/ko
Priority to CN200680009678XA priority patent/CN101146817B/zh
Priority to MX2007011849A priority patent/MX2007011849A/es
Priority to JP2008502445A priority patent/JP5036698B2/ja
Priority to AU2006226251A priority patent/AU2006226251B2/en
Priority to BRPI0609211-0A priority patent/BRPI0609211A2/pt
Application filed by Laboratories Fournier SAS filed Critical Laboratories Fournier SAS
Publication of WO2006100413A2 publication Critical patent/WO2006100413A2/fr
Publication of WO2006100413A3 publication Critical patent/WO2006100413A3/fr
Priority to IL185691A priority patent/IL185691A/en
Priority to NO20074609A priority patent/NO20074609L/no
Priority to TNP2007000362A priority patent/TNSN07362A1/fr
Anticipated expiration legal-status Critical
Publication of WO2006100413A9 publication Critical patent/WO2006100413A9/fr
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/20—Carbocyclic rings
    • C07H15/203—Monocyclic carbocyclic rings other than cyclohexane rings; Bicyclic carbocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02—Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne de nouveaux composés du 5-thioxylose, préférentiellement des dérivés de type 5-thioxylopyranose, ainsi que leur procédé de préparation et leur utilisation en tant que principe actif de médicaments, notamment destinés au traitement ou à la prévention des thromboses ou de l'insuffisance cardiaque.
PCT/FR2006/050259 2005-03-25 2006-03-24 Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique Ceased WO2006100413A2 (fr)

Priority Applications (12)

Application Number Priority Date Filing Date Title
BRPI0609211-0A BRPI0609211A2 (pt) 2005-03-25 2006-03-24 novos compostos derivados de 5-tioxilose e seus usos terapÊuticos
EP06726275A EP1861411A2 (fr) 2005-03-25 2006-03-24 Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique
KR1020077021135A KR101336547B1 (ko) 2005-03-25 2006-03-24 5-티옥실로스로부터 유도된 신규한 화합물 및 그의 치료적용도
CN200680009678XA CN101146817B (zh) 2005-03-25 2006-03-24 5-硫代木糖衍生的新型化合物及其在治疗中的应用
MX2007011849A MX2007011849A (es) 2005-03-25 2006-03-24 Compuestos novedosos derivados de 5-tioxilosa, y su uso en terapeutica.
JP2008502445A JP5036698B2 (ja) 2005-03-25 2006-03-24 ５−チオキシロースから誘導される新規化合物及び治療におけるその使用
AU2006226251A AU2006226251B2 (en) 2005-03-25 2006-03-24 Novel compounds derived from 5-thioxylose and therapeutic use thereof
CA002602698A CA2602698A1 (fr) 2005-03-25 2006-03-24 Composes derives du 5-thioxylose et leur utilisation dans le traitement ou la prevention des thromboses ou de l'insuffisance cardiaque
US11/909,489 US8148407B2 (en) 2005-03-25 2006-03-24 Compounds derived from 5-thioxylose and their use in therapeutics
IL185691A IL185691A (en) 2005-03-25 2007-09-03 5-thioxylose derivatives, process for their preparation and use thereof in the preparation of medicaments for the prevention or treatment of thrombosis
NO20074609A NO20074609L (no) 2005-03-25 2007-09-12 Nye forbindelser avledet fra 5-tioksylose og terapeutisk anvendelse derav
TNP2007000362A TNSN07362A1 (fr) 2005-03-25 2007-09-24 Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0502978 2005-03-25
FR0502978A FR2883561B1 (fr) 2005-03-25 2005-03-25 Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique

Publications (3)

Publication Number Publication Date
WO2006100413A2 WO2006100413A2 (fr) 2006-09-28
WO2006100413A3 true WO2006100413A3 (fr) 2006-11-09
WO2006100413A9 WO2006100413A9 (fr) 2007-10-18

Family

ID=34955178

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/FR2006/050259 Ceased WO2006100413A2 (fr) 2005-03-25 2006-03-24 Nouveaux composes derives du 5-thioxylose et leur utilisation therapeutique

Country Status (18)

Country Link
US (1) US8148407B2 (fr)
EP (1) EP1861411A2 (fr)
JP (1) JP5036698B2 (fr)
KR (1) KR101336547B1 (fr)
CN (1) CN101146817B (fr)
AU (1) AU2006226251B2 (fr)
BR (1) BRPI0609211A2 (fr)
CA (1) CA2602698A1 (fr)
FR (1) FR2883561B1 (fr)
IL (1) IL185691A (fr)
MA (1) MA29372B1 (fr)
MX (1) MX2007011849A (fr)
NO (1) NO20074609L (fr)
RU (1) RU2412195C2 (fr)
TN (1) TNSN07362A1 (fr)
UA (1) UA92908C2 (fr)
WO (1) WO2006100413A2 (fr)
ZA (1) ZA200707947B (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2906248B1 (fr) * 2006-09-27 2008-12-26 Fournier S A Sa Lab Nouveaux derives de 5-thioxylopyranose
CN113527536B (zh) * 2020-04-21 2024-03-22 杭州德柯医疗科技有限公司 一种含氟多糖高分子化合物及其制备方法

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0290321A1 (fr) * 1987-05-04 1988-11-09 Fournier Industrie Et Sante Nouveaux beta-D-phényl-thioxylosides, leur procédé de préparation et leur application en thérapeutique
EP0365397A2 (fr) * 1988-10-18 1990-04-25 Fournier Industrie Et Sante Nouveaux beta-D-phényl-thioxylosides, leur procédé de préparation et leur utilisation en thérapeutique
EP0367671A2 (fr) * 1988-11-03 1990-05-09 Fournier Industrie Et Sante Bêta-D-phénylthioxylosides, procédé pour leur préparation et leur utilisation comme médicaments
EP0451007A1 (fr) * 1990-04-02 1991-10-09 Fournier Industrie Et Sante Sulfonyl-phényl-beta-D-thioxylosides, leur procédé de préparation et leur utilisation en thérapeutique
US5246961A (en) * 1988-10-18 1993-09-21 Fournier Industrie Et Sante β-d-phenylthioxylosides, and their use as therapeutic agents
FR2860234A1 (fr) * 2003-09-25 2005-04-01 Fournier Lab Sa Nouveaux derives 666 du thioxylose

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0753747B2 (ja) * 1988-11-03 1995-06-07 フルニエ アンデュストリ エ サンテ β―Ｄ―フェニルチオキシロシド、その調製方法および薬剤としての使用
FR2801055B1 (fr) * 1999-11-17 2002-02-08 Fournier Ind & Sante Derives de beta-d-5-thioxylose, procede de preparation et utilisation en therapeutique
JPWO2004089966A1 (ja) * 2003-04-01 2006-07-06 大正製薬株式会社 選択的なヘテロアリール５−チオ−β−Ｄ−アルドヘキソピラノシドの製造法

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0290321A1 (fr) * 1987-05-04 1988-11-09 Fournier Industrie Et Sante Nouveaux beta-D-phényl-thioxylosides, leur procédé de préparation et leur application en thérapeutique
EP0365397A2 (fr) * 1988-10-18 1990-04-25 Fournier Industrie Et Sante Nouveaux beta-D-phényl-thioxylosides, leur procédé de préparation et leur utilisation en thérapeutique
US5246961A (en) * 1988-10-18 1993-09-21 Fournier Industrie Et Sante β-d-phenylthioxylosides, and their use as therapeutic agents
EP0367671A2 (fr) * 1988-11-03 1990-05-09 Fournier Industrie Et Sante Bêta-D-phénylthioxylosides, procédé pour leur préparation et leur utilisation comme médicaments
EP0451007A1 (fr) * 1990-04-02 1991-10-09 Fournier Industrie Et Sante Sulfonyl-phényl-beta-D-thioxylosides, leur procédé de préparation et leur utilisation en thérapeutique
FR2860234A1 (fr) * 2003-09-25 2005-04-01 Fournier Lab Sa Nouveaux derives 666 du thioxylose

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
BELLAMY F ET AL: "THIOXYLOSIDE DERIVATIVES AS ORALLY ACTIVE VENOUS ANTITHROMBOTICS", EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, EDITIONS SCIENTIFIQUE ELSEVIER, PARIS, FR, vol. 30, 1995, pages 101S - 115S, XP002042895, ISSN: 0223-5234 *

Also Published As

Publication number Publication date
IL185691A0 (en) 2008-01-06
JP5036698B2 (ja) 2012-09-26
WO2006100413A2 (fr) 2006-09-28
AU2006226251B2 (en) 2012-01-19
ZA200707947B (en) 2008-12-31
TNSN07362A1 (fr) 2008-12-31
US20080293768A1 (en) 2008-11-27
RU2007135251A (ru) 2009-04-27
CA2602698A1 (fr) 2006-09-28
FR2883561A1 (fr) 2006-09-29
MA29372B1 (fr) 2008-04-01
RU2412195C2 (ru) 2011-02-20
BRPI0609211A2 (pt) 2010-03-02
FR2883561B1 (fr) 2009-03-20
MX2007011849A (es) 2007-10-03
CN101146817B (zh) 2011-08-17
WO2006100413A9 (fr) 2007-10-18
IL185691A (en) 2012-02-29
KR20070114357A (ko) 2007-12-03
UA92908C2 (ru) 2010-12-27
AU2006226251A1 (en) 2006-09-28
KR101336547B1 (ko) 2013-12-03
NO20074609L (no) 2007-12-12
CN101146817A (zh) 2008-03-19
JP2008535813A (ja) 2008-09-04
EP1861411A2 (fr) 2007-12-05
US8148407B2 (en) 2012-04-03

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