WO2008090905A1 - 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物 - Google Patents

保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物 Download PDF

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Publication number
WO2008090905A1
WO2008090905A1 PCT/JP2008/050852 JP2008050852W WO2008090905A1 WO 2008090905 A1 WO2008090905 A1 WO 2008090905A1 JP 2008050852 W JP2008050852 W JP 2008050852W WO 2008090905 A1 WO2008090905 A1 WO 2008090905A1
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dry yeast
adenosyl
methionine
yeast
storage stability
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Ceased
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PCT/JP2008/050852
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English (en)
French (fr)
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Kentarou Takano
Shinyo Gayama
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Mitsubishi Gas Chemical Co Inc
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Mitsubishi Gas Chemical Co Inc
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Priority to CA2675970A priority Critical patent/CA2675970C/en
Priority to AU2008208325A priority patent/AU2008208325B2/en
Priority to CN2008800027844A priority patent/CN101589136B/zh
Priority to US12/524,050 priority patent/US9200250B2/en
Priority to KR1020097014889A priority patent/KR101525263B1/ko
Priority to EP08703696.8A priority patent/EP2116593B1/en
Priority to JP2008555081A priority patent/JP4479932B2/ja
Publication of WO2008090905A1 publication Critical patent/WO2008090905A1/ja
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • C12N1/18—Baker's yeast; Brewer's yeast
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C12N1/16—Yeasts; Culture media therefor
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/13—Nucleic acids or derivatives thereof
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/14—Yeasts or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/04—Preserving or maintaining viable microorganisms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/12—Methionine; Cysteine; Cystine
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Food Science & Technology (AREA)
  • Botany (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

　本発明はＳ－アデノシル－Ｌ－メチオニン生産能を有する酵母を用い、Ｓ－アデノシル－Ｌ－メチオニンを含有する乾燥酵母を製造する方法において、酵母の菌体培養液より得られる酵母菌体濃縮物にシクロデキストリン類を添加した後に乾燥することを特徴とする、Ｓ－アデノシル－Ｌ－メチオニン含有乾燥酵母の製造方法、該製造方法で得られたＳＡＭｅ含有乾燥酵母、及び該乾燥酵母を用いて成形された組成物に関するものである。本発明によって水溶性の生理活性物質として有用なＳ－アデノシル－Ｌ－メチオニンを高濃度に含む保存安定性に優れた乾燥酵母及び該乾燥を用いて成型された組成物を簡便かつ経済的に製造し、市場に提供することが可能となる。
PCT/JP2008/050852 2007-01-25 2008-01-23 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物 Ceased WO2008090905A1 (ja)

Priority Applications (7)

Application Number Priority Date Filing Date Title
CA2675970A CA2675970C (en) 2007-01-25 2008-01-23 Method for production of dry yeast containing s-adenosyl-l-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
AU2008208325A AU2008208325B2 (en) 2007-01-25 2008-01-23 Method for production of dry yeast containing S-adenosyl-L-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
CN2008800027844A CN101589136B (zh) 2007-01-25 2008-01-23 储存稳定性优良的含s-腺苷-l-甲硫氨酸的干燥酵母的制备方法及其产品以及由该产品成型而得到的组合物
US12/524,050 US9200250B2 (en) 2007-01-25 2008-01-23 Method for production of dry yeast containing S-adenosyl-L-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
KR1020097014889A KR101525263B1 (ko) 2007-01-25 2008-01-23 보존 안정성이 뛰어난 ｓ-아데노실-ｌ-메티오닌 함유 건조 효모의 제조 방법, 그 제조물 및 그 성형된 조성물
EP08703696.8A EP2116593B1 (en) 2007-01-25 2008-01-23 Method for production of dry yeast containing s-adenosyl-l-methionine and having excellent storage stability, product produced by the method, and molded composition of the dry yeast
JP2008555081A JP4479932B2 (ja) 2007-01-25 2008-01-23 保存安定性に優れたｓ−アデノシル−ｌ−メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2007-015257 2007-01-25
JP2007015257 2007-01-25

Publications (1)

Publication Number Publication Date
WO2008090905A1 true WO2008090905A1 (ja) 2008-07-31

Family

ID=39644479

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2008/050852 Ceased WO2008090905A1 (ja) 2007-01-25 2008-01-23 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母の製造方法、その製造物及びその成型された組成物

Country Status (11)

Country Link
US (1) US9200250B2 (ja)
EP (1) EP2116593B1 (ja)
JP (1) JP4479932B2 (ja)
KR (1) KR101525263B1 (ja)
CN (1) CN101589136B (ja)
AU (1) AU2008208325B2 (ja)
CA (1) CA2675970C (ja)
PT (1) PT2116593T (ja)
TR (1) TR201802640T4 (ja)
TW (1) TWI403585B (ja)
WO (1) WO2008090905A1 (ja)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011126030A1 (ja) 2010-04-07 2011-10-13 三菱瓦斯化学株式会社 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母組成物及びその製造方法
WO2013024663A1 (ja) * 2011-08-12 2013-02-21 三菱瓦斯化学株式会社 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有組成物
JP2013047222A (ja) * 2011-07-27 2013-03-07 Lion Corp 皮膚老化予防改善剤
JPWO2014163151A1 (ja) * 2013-04-05 2017-02-16 ライオン株式会社 酵母培養物及び内服組成物
JPWO2014163150A1 (ja) * 2013-04-05 2017-02-16 ライオン株式会社 内服組成物

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102321136B (zh) * 2011-09-19 2014-10-22 北京化工大学 S-腺苷-l-甲硫氨酸对甲苯磺酸硫酸双盐的制备方法
JP5989319B2 (ja) * 2011-10-06 2016-09-07 ライオン株式会社 睡眠の質改善剤
CN103704723A (zh) * 2013-12-11 2014-04-09 北京凯因科技股份有限公司 一种富含活性氨基酸的营养配制品
CN104140996B (zh) * 2014-08-04 2016-06-01 宁波美康生物科技股份有限公司 液体稳定酶法同型半胱氨酸试剂盒
JP6159860B1 (ja) * 2016-08-31 2017-07-05 株式会社ホルス ＳＡＭｅ含有液体原料が配合されたクリーム状、ジェル状又は液状の外用剤、化粧品又は健康食品の製造方法
FR3080041B1 (fr) * 2018-04-17 2020-10-16 Roquette Freres Composition emulsifiante a usage cosmetique, pour l'obtention d'une emulsion de pickering h/e, et procede de fabrication d'une telle emulsion

Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5248691A (en) 1975-10-16 1977-04-18 Yamasa Shoyu Co Ltd Method of stabilizing s-adenosyl-l-methionine
JPS5951213A (ja) 1982-09-17 1984-03-24 Kanegafuchi Chem Ind Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物およびその製造法
JPS60181095A (ja) 1984-02-27 1985-09-14 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
JPS6191125A (ja) 1984-10-11 1986-05-09 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
JPS61227792A (ja) 1985-01-25 1986-10-09 イ−ライ・リリ−・アンド・カンパニ− 純化したメチオニンアデノシル転移酵素を使用するｓ−アデノシルメチオニンの酵素的合成法
JPH0149275B2 (ja) 1981-08-24 1989-10-24 Bioresearch Spa
JPH0149274B2 (ja) 1981-08-24 1989-10-24 Bioresearch Spa
JPH03501970A (ja) 1987-10-09 1991-05-09 ザッピア　ヴィンセンツォ Ｓ‐アデノシル‐ｌ‐メチオニン（ｓａｍ）のアシル化タウリン誘導体との親油性塩
JPH0421478B2 (ja) 1983-08-24 1992-04-10 Bioresearch Spa
JPH0630607B2 (ja) 1984-05-16 1994-04-27 バイオリサーチ・エス．ピー．エイ 非経口用に特に適した安定なスルホ‐アデノシル‐ｌ‐メチオニン塩
EP1091001A1 (en) 1999-10-05 2001-04-11 CHEMENTECNO S.r.l. Process for the purification of S-adenosyl-L-methionine and for the preparation of the pharmaceutically acceptable salts thereof
JP2001169797A (ja) 1999-10-08 2001-06-26 Yamasa Shoyu Co Ltd Ｓ―アデノシル−ｌ−メチオニンの酵素的製造法
JP2002017337A (ja) * 2000-05-02 2002-01-22 Biofuerumin Seiyaku Kk 噴霧乾燥による菌体乾燥物
US6881837B2 (en) 2001-06-07 2005-04-19 Orchid Chemicals & Pharmaceuticals Ltd. Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer
JP2005229812A (ja) 2004-02-17 2005-09-02 Kohjin Co Ltd 安定化されたｓａｍを含有する乾燥微生物又は微生物抽出物、及びその製造方法
WO2005084646A1 (en) * 2004-03-01 2005-09-15 Britannia Pharmaceuticals Limited Powdered compositions of sensitive active materials in an at least partially amorphous state

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS545092A (en) * 1977-06-14 1979-01-16 Miyarisan Pharma Production of odor free strains
JPH0657084B2 (ja) * 1984-06-19 1994-08-03 ヤンマー農機株式会社 田植機の苗植装置
IT1200589B (it) * 1985-02-14 1989-01-27 Gibipharma Spa Derivati naturali attivita farmagologica
JPH0421478A (ja) 1990-05-16 1992-01-24 Nec Corp データ印刷制御方式
JPH0630607A (ja) 1992-07-20 1994-02-08 Yanmar Agricult Equip Co Ltd い草移植機の植付爪
JP2001186862A (ja) 1999-10-19 2001-07-10 Makoto Hiuga 粉末状アウレオバシジウム培養液組成物及びその製造方法並びにその組成物を用いた粉末混合物
CN100363499C (zh) * 2006-02-27 2008-01-23 上海国佳生化工程技术研究中心有限公司 一种新的腺苷甲硫氨酸的体外酶促转化方法

Patent Citations (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5248691A (en) 1975-10-16 1977-04-18 Yamasa Shoyu Co Ltd Method of stabilizing s-adenosyl-l-methionine
JPH0149275B2 (ja) 1981-08-24 1989-10-24 Bioresearch Spa
JPH0149274B2 (ja) 1981-08-24 1989-10-24 Bioresearch Spa
JPS5951213A (ja) 1982-09-17 1984-03-24 Kanegafuchi Chem Ind Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物およびその製造法
JPH0421478B2 (ja) 1983-08-24 1992-04-10 Bioresearch Spa
JPS60181095A (ja) 1984-02-27 1985-09-14 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
JPH0630607B2 (ja) 1984-05-16 1994-04-27 バイオリサーチ・エス．ピー．エイ 非経口用に特に適した安定なスルホ‐アデノシル‐ｌ‐メチオニン塩
JPS6191125A (ja) 1984-10-11 1986-05-09 Nippon Zeon Co Ltd Ｓ−アデノシル−ｌ−メチオニン含有組成物及びその製造法
JPS61227792A (ja) 1985-01-25 1986-10-09 イ−ライ・リリ−・アンド・カンパニ− 純化したメチオニンアデノシル転移酵素を使用するｓ−アデノシルメチオニンの酵素的合成法
JPH03501970A (ja) 1987-10-09 1991-05-09 ザッピア　ヴィンセンツォ Ｓ‐アデノシル‐ｌ‐メチオニン（ｓａｍ）のアシル化タウリン誘導体との親油性塩
EP1091001A1 (en) 1999-10-05 2001-04-11 CHEMENTECNO S.r.l. Process for the purification of S-adenosyl-L-methionine and for the preparation of the pharmaceutically acceptable salts thereof
JP2001169797A (ja) 1999-10-08 2001-06-26 Yamasa Shoyu Co Ltd Ｓ―アデノシル−ｌ−メチオニンの酵素的製造法
JP2002017337A (ja) * 2000-05-02 2002-01-22 Biofuerumin Seiyaku Kk 噴霧乾燥による菌体乾燥物
US6881837B2 (en) 2001-06-07 2005-04-19 Orchid Chemicals & Pharmaceuticals Ltd. Chemical synthesis of S-adenosyl-L-methionine with enrichment of (S,S)-isomer
JP2005229812A (ja) 2004-02-17 2005-09-02 Kohjin Co Ltd 安定化されたｓａｍを含有する乾燥微生物又は微生物抽出物、及びその製造方法
WO2005084646A1 (en) * 2004-03-01 2005-09-15 Britannia Pharmaceuticals Limited Powdered compositions of sensitive active materials in an at least partially amorphous state

Non-Patent Citations (12)

* Cited by examiner, † Cited by third party
Title
JEONGHO PARK ET AL., BIOORGANIC & MEDICAL CHEMISTRY, vol. 4, no. 12, 1996, pages 2179 - 2185
JOSE R. MATOR; FRANK M. RAUSHEL; HI-HUEY WONG., BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY, vol. 9, 1987, pages 39 - 52
KUSAKABE H.; KUNINAKA A.; YOSHINO H., AGRIC. BIOL. CHEM., vol. 38, 1974, pages 1669 - 1672
MARKHAM DJ.; DEPARISIS J., J. BIOL. CHEM., vol. 259, 1984, pages 14505 - 14507
MARKHAM G.D. ET AL., J. BIOL. CHEM., vol. 255, 1980, pages 9082 - 9092
MUDD SH.; CANTONI GL. ET AL., J. BIOL. CHEM., vol. 231, 1958, pages 481 - 492
SCHLENK F.; DEPALMA R.E., J. BIOL. CHEM., vol. 229, 1957, pages 1037 - 1050
SHIOZAKI S. ET AL., AGRIC. BIOL. CHEM., vol. 48, 1984, pages 2293 - 2300
SHIOZAKI S. ET AL., AGRIC. BIOL. CHEM., vol. 53, 1989, pages 3269 - 3274
SHIOZAKI S. ET AL., J. BIOTECHNOLOGY, vol. 4, 1986, pages 345 - 354
THOMAS D.; CHEREST H. ET AL., MOL. CELL. BIOL., vol. 8, 1988, pages 5132 - 5139
THOMAS D.; SURDIN-KERJANY., J. BIOL. CHEM., vol. 262, 1987, pages 16704 - 16709

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011126030A1 (ja) 2010-04-07 2011-10-13 三菱瓦斯化学株式会社 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有乾燥酵母組成物及びその製造方法
JPWO2011126030A1 (ja) * 2010-04-07 2013-07-11 三菱瓦斯化学株式会社 保存安定性に優れたｓ−アデノシル−ｌ−メチオニン含有乾燥酵母組成物及びその製造方法
RU2579972C2 (ru) * 2010-04-07 2016-04-10 Мицубиси Гэс Кемикал Компани, Инк. Стабильная при хранении содержащая s-аденозил-l-метионин композиция высушенных дрожжей и способ ее производства
US9404076B2 (en) 2010-04-07 2016-08-02 Mitsubishi Gas Chemical Company, Inc. S-adenosyl-L-methionine-containing dry yeast composition with excellent storage stability and process for producing same
EP3214167A1 (en) 2010-04-07 2017-09-06 Mitsubishi Gas Chemical Company, Inc. S-adenosyl-l-methionine-containing dry yeast composition with excellent storage stability and process for producing same
JP2013047222A (ja) * 2011-07-27 2013-03-07 Lion Corp 皮膚老化予防改善剤
WO2013024663A1 (ja) * 2011-08-12 2013-02-21 三菱瓦斯化学株式会社 保存安定性に優れたｓ－アデノシル－ｌ－メチオニン含有組成物
JPWO2013024663A1 (ja) * 2011-08-12 2015-03-05 三菱瓦斯化学株式会社 保存安定性に優れたｓ−アデノシル−ｌ−メチオニン含有組成物
US9700629B2 (en) 2011-08-12 2017-07-11 Mitsubishi Gas Chemical Company, Inc. Composition containing S-adenosyl-L-methionine with excellent storage stability
JPWO2014163151A1 (ja) * 2013-04-05 2017-02-16 ライオン株式会社 酵母培養物及び内服組成物
JPWO2014163150A1 (ja) * 2013-04-05 2017-02-16 ライオン株式会社 内服組成物

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