WO2009146151A3 - Dispositifs de greffe de la cornée et procédés - Google Patents

Dispositifs de greffe de la cornée et procédés Download PDF

Info

Publication number
WO2009146151A3
WO2009146151A3 PCT/US2009/039675 US2009039675W WO2009146151A3 WO 2009146151 A3 WO2009146151 A3 WO 2009146151A3 US 2009039675 W US2009039675 W US 2009039675W WO 2009146151 A3 WO2009146151 A3 WO 2009146151A3
Authority
WO
WIPO (PCT)
Prior art keywords
onlay
cornea
adhere
layer
methods
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2009/039675
Other languages
English (en)
Other versions
WO2009146151A2 (fr
Inventor
Eugene De Juan
Cary J. Reich
Stephen Boyd
David Sierra
Jose D. Alejandro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
ForSight Labs LLC
Original Assignee
ForSight Labs LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ForSight Labs LLC filed Critical ForSight Labs LLC
Priority to EP09755513A priority Critical patent/EP2296580A2/fr
Publication of WO2009146151A2 publication Critical patent/WO2009146151A2/fr
Publication of WO2009146151A3 publication Critical patent/WO2009146151A3/fr
Priority to US12/897,131 priority patent/US9125735B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/007—Methods or devices for eye surgery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/142—Cornea, e.g. artificial corneae, keratoprostheses or corneal implants for repair of defective corneal tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
    • A61F2/1451—Inlays or onlays
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses or corneal implants; Artificial eyes
    • A61F2/145—Corneal inlays, onlays, or lenses for refractive correction
    • A61F2/1453—Corneal lenses connected to distinct attachment means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
    • A61F2250/0019—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in hardness, e.g. Vickers, Shore, Brinell
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00—Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017—Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Ophthalmology & Optometry (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cardiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Surgery (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Selon l’invention, une greffe de cornée est configurée pour adhérer à la cornée de manière à inhiber la croissance épithéliale sous la greffe. Des structures peuvent être fournies sur la greffe pour faire adhérer la greffe à l’œil. Au moins l’une parmi une couche épithéliale ou la couche anti-eau peut être disposée sur ou au-dessus de la greffe, par exemple une couche épithéliale naturelle ou une couche anti-eau qui inhibe, par exemple minimise, la pénétration d’eau dans la greffe, de manière à faire adhérer la greffe à l’œil avec pompage de l’endothélium. La couche anti-eau peut comprendre un revêtement thérapeutique positionné sur la greffe pour inhiber le gonflement de la cornée. La surface postérieure de la greffe peut être formée de manière à s’adapter à la surface exposée antérieure de la cornée.
PCT/US2009/039675 2008-04-04 2009-04-06 Dispositifs de greffe de la cornée et procédés Ceased WO2009146151A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP09755513A EP2296580A2 (fr) 2008-04-04 2009-04-06 Dispositifs de greffe de la cornée et procédés
US12/897,131 US9125735B2 (en) 2008-04-04 2010-10-04 Method of correcting vision using corneal onlays

Applications Claiming Priority (14)

Application Number Priority Date Filing Date Title
US4258908P 2008-04-04 2008-04-04
US4259408P 2008-04-04 2008-04-04
US61/042,594 2008-04-04
US61/042,589 2008-04-04
US5014708P 2008-05-02 2008-05-02
US5010608P 2008-05-02 2008-05-02
US61/050,147 2008-05-02
US61/050,106 2008-05-02
US19191508P 2008-09-11 2008-09-11
US61/191,915 2008-09-11
US11971208P 2008-12-03 2008-12-03
US61/119,712 2008-12-03
US21181509P 2009-04-03 2009-04-03
US61/211,815 2009-04-03

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US12/897,131 Continuation US9125735B2 (en) 2008-04-04 2010-10-04 Method of correcting vision using corneal onlays

Publications (2)

Publication Number Publication Date
WO2009146151A2 WO2009146151A2 (fr) 2009-12-03
WO2009146151A3 true WO2009146151A3 (fr) 2010-01-14

Family

ID=41258210

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2009/039675 Ceased WO2009146151A2 (fr) 2008-04-04 2009-04-06 Dispositifs de greffe de la cornée et procédés

Country Status (2)

Country Link
EP (1) EP2296580A2 (fr)
WO (1) WO2009146151A2 (fr)

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US9020580B2 (en) 2011-06-02 2015-04-28 Avedro, Inc. Systems and methods for monitoring time based photo active agent delivery or photo active marker presence
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498642B2 (en) 2009-10-21 2016-11-22 Avedro, Inc. Eye therapy system
US9498122B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US10285857B2 (en) 2010-09-30 2019-05-14 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use

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US8401212B2 (en) 2007-10-12 2013-03-19 Earlens Corporation Multifunction system and method for integrated hearing and communication with noise cancellation and feedback management
US7668325B2 (en) 2005-05-03 2010-02-23 Earlens Corporation Hearing system having an open chamber for housing components and reducing the occlusion effect
US8545487B2 (en) 2007-12-05 2013-10-01 Avedro Inc. Eye therapy system
US9943401B2 (en) 2008-04-04 2018-04-17 Eugene de Juan, Jr. Therapeutic device for pain management and vision
WO2009155358A1 (fr) 2008-06-17 2009-12-23 Earlens Corporation Dispositifs d’audition électromécaniques optiques dotés de composants d’alimentation et de signal séparés
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US8506473B2 (en) 2008-12-16 2013-08-13 SoundBeam LLC Hearing-aid transducer having an engineered surface
US8109997B2 (en) * 2009-01-18 2012-02-07 Eyeon Medical Ltd. Hydrophobic pseudo-endothelial implants for treating corneal edema
EP2490620A4 (fr) 2009-10-23 2017-03-22 Forsight Labs, Llc Écran thérapeutique adaptable pour la vision et la douleur
US20130066283A1 (en) 2009-10-23 2013-03-14 Nexisvision, Inc. Corneal Denervation for Treatment of Ocular Pain
US20110237999A1 (en) 2010-03-19 2011-09-29 Avedro Inc. Systems and methods for applying and monitoring eye therapy
EP3758394A1 (fr) 2010-12-20 2020-12-30 Earlens Corporation Appareil auditif intra-auriculaire anatomiquement personnalisé
US12044905B2 (en) 2011-04-28 2024-07-23 Journey1 Inc Contact lenses for refractive correction
US9044308B2 (en) 2011-05-24 2015-06-02 Avedro, Inc. Systems and methods for reshaping an eye feature
US9555111B2 (en) 2012-03-29 2017-01-31 Cxl Ophthalmics, Llc Ocular cross-linking system and method for sealing corneal wounds
WO2013149075A1 (fr) 2012-03-29 2013-10-03 Cxl Ophthalmics, Llc Compositions et procédés de traitement ou de prévention de maladies associées au stress oxydatif
EP4420725A3 (fr) 2012-03-29 2025-04-16 Epion Therapeutics, Inc. Solutions de traitement oculaire, dispositifs d'administration et procédés améliorant l'administration
WO2013059837A2 (fr) 2012-07-16 2013-04-25 Avedro, Inc. Systèmes et procédés pour une réticulation cornéenne avec une lumière pulsée
US10092393B2 (en) 2013-03-14 2018-10-09 Allotex, Inc. Corneal implant systems and methods
CN103272268B (zh) * 2013-05-16 2015-04-22 华南理工大学 一种抗菌角膜修复材料及其制备方法
JP6310072B2 (ja) 2013-06-26 2018-04-11 ネクシスビジョン， インコーポレイテッド 屈折矯正のためのコンタクトレンズ
US10034103B2 (en) 2014-03-18 2018-07-24 Earlens Corporation High fidelity and reduced feedback contact hearing apparatus and methods
DK3169396T3 (da) 2014-07-14 2021-06-28 Earlens Corp Glidende forspænding og peak-begrænsning for optiske høreapparater
KR102416876B1 (ko) 2014-10-27 2022-07-05 아베드로 인코퍼레이티드 눈의 교차-결합 처리를 위한 시스템 및 방법
US10114205B2 (en) 2014-11-13 2018-10-30 Avedro, Inc. Multipass virtually imaged phased array etalon
US9924276B2 (en) 2014-11-26 2018-03-20 Earlens Corporation Adjustable venting for hearing instruments
EP3285704B1 (fr) 2015-04-24 2020-11-18 Avedro Inc. Systèmes pour photoactiver un photosensibilisant appliqué à un oeil
US10028657B2 (en) 2015-05-22 2018-07-24 Avedro, Inc. Systems and methods for monitoring cross-linking activity for corneal treatments
US11207410B2 (en) 2015-07-21 2021-12-28 Avedro, Inc. Systems and methods for treatments of an eye with a photosensitizer
US10449090B2 (en) 2015-07-31 2019-10-22 Allotex, Inc. Corneal implant systems and methods
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US11350226B2 (en) 2015-12-30 2022-05-31 Earlens Corporation Charging protocol for rechargeable hearing systems
WO2017116791A1 (fr) 2015-12-30 2017-07-06 Earlens Corporation Systèmes, appareil et procédés auditifs reposant sur la lumière
US10492010B2 (en) 2015-12-30 2019-11-26 Earlens Corporations Damping in contact hearing systems
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US20190201710A1 (en) * 2016-09-27 2019-07-04 KeraMed, Inc. System, device, and method for cross-linking corneal tissue
WO2018093733A1 (fr) 2016-11-15 2018-05-24 Earlens Corporation Procédure d'impression améliorée
US10966863B2 (en) 2018-01-08 2021-04-06 EyeYon Medical Ltd. Treatment to improve adhesive properties of corneal implant
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WO2022192237A1 (fr) 2021-03-08 2022-09-15 Avedro, Inc. Systèmes et méthodes de génération de schémas de traitement de cross linking du collagène cornéen spécifiques au patient
US11737919B2 (en) 2021-06-17 2023-08-29 EyeYon Medical Ltd. Endothelial ocular implant
WO2022272082A1 (fr) * 2021-06-24 2022-12-29 Rvo 2.0, Inc, D/B/A Optics Medical Dispositif médical d'onlay cornéen
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US4810082A (en) * 1987-07-01 1989-03-07 Abel Robert Jr Corneal onlay lens
EP0434205A2 (fr) * 1989-11-22 1991-06-26 Allergan, Inc Lentille cornéenne et sa méthode de fixation
WO1995013764A1 (fr) * 1993-11-19 1995-05-26 Ciba-Geigy Ag Implants de cornee
WO2000009042A1 (fr) * 1998-08-12 2000-02-24 Novartis Ag Onlay corneen
WO2002068008A1 (fr) * 2001-02-28 2002-09-06 Novartis Pharma Gmbh Dispositifs medicaux pourvus d'un revetement
WO2003097759A1 (fr) * 2002-05-21 2003-11-27 Commonwealth Scientific And Industrial Research Organisation Adhesif biomedical
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US20050259221A1 (en) * 2004-05-20 2005-11-24 Coopervision, Inc Corneal onlays and wavefront aberration correction to enhance vision
CA2174967C (fr) * 1993-11-19 2006-03-14 John Gerard Steele Implants de cornee
US20060083773A1 (en) * 2004-10-05 2006-04-20 David Myung Artificial corneal implant
US20060241751A1 (en) * 2002-09-13 2006-10-26 Marmo J C Corneal onlays and methods of producing same

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US20050259221A1 (en) * 2004-05-20 2005-11-24 Coopervision, Inc Corneal onlays and wavefront aberration correction to enhance vision
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Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9498642B2 (en) 2009-10-21 2016-11-22 Avedro, Inc. Eye therapy system
US10285857B2 (en) 2010-09-30 2019-05-14 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US11033429B2 (en) 2010-09-30 2021-06-15 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US11135090B2 (en) 2010-09-30 2021-10-05 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US12156834B2 (en) 2010-09-30 2024-12-03 Cxl Ophthalmics, Llc Ophthalmic treatment device, system, and method of use
US9020580B2 (en) 2011-06-02 2015-04-28 Avedro, Inc. Systems and methods for monitoring time based photo active agent delivery or photo active marker presence
US9498114B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment
US9498122B2 (en) 2013-06-18 2016-11-22 Avedro, Inc. Systems and methods for determining biomechanical properties of the eye for applying treatment

Also Published As

Publication number Publication date
WO2009146151A2 (fr) 2009-12-03
EP2296580A2 (fr) 2011-03-23

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