WO2010100212A1 - Mélangeur multifonction pour des applications de laboratoire - Google Patents

Mélangeur multifonction pour des applications de laboratoire Download PDF

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Publication number
WO2010100212A1
WO2010100212A1 PCT/EP2010/052725 EP2010052725W WO2010100212A1 WO 2010100212 A1 WO2010100212 A1 WO 2010100212A1 EP 2010052725 W EP2010052725 W EP 2010052725W WO 2010100212 A1 WO2010100212 A1 WO 2010100212A1
Authority
WO
WIPO (PCT)
Prior art keywords
magnets
magnetic
coupling
elements
gear
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2010/052725
Other languages
German (de)
English (en)
Other versions
WO2010100212A9 (fr
Inventor
Heyo Mennenga
Armin Winkler
Jan Michael Heinrich
Christoph Mohr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rational Technische Losungen GmbH
Original Assignee
Rational Technische Losungen GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rational Technische Losungen GmbH filed Critical Rational Technische Losungen GmbH
Publication of WO2010100212A1 publication Critical patent/WO2010100212A1/fr
Publication of WO2010100212A9 publication Critical patent/WO2010100212A9/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/60—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers
    • B01F29/62—Mixers with rotating receptacles rotating about a horizontal or inclined axis, e.g. drum mixers without bars, i.e. without mixing elements; characterised by the shape or cross section of the receptacle, e.g. of Y-, Z-, S- or X- shape; with cylindrical receptacles rotating about an axis at an angle to their longitudinal axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F29/00—Mixers with rotating receptacles
    • B01F29/20—Mixers with rotating receptacles with receptacles rotating about an axis at an angle to their longitudinal axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/23—Mixing the contents of independent containers, e.g. test tubes by pivoting the containers about an axis
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F31/00—Mixers with shaking, oscillating, or vibrating mechanisms
    • B01F31/20—Mixing the contents of independent containers, e.g. test tubes
    • B01F31/265—Mixing the contents of independent containers, e.g. test tubes the vibrations being caused by an unbalanced rotating member
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/2201—Control or regulation characterised by the type of control technique used
    • B01F35/2205—Controlling the mixing process from a remote server, e.g. by sending commands using radio, telephone, internet, local network, GPS or other means
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/20—Measuring; Control or regulation
    • B01F35/22—Control or regulation
    • B01F35/2201—Control or regulation characterised by the type of control technique used
    • B01F35/2209—Controlling the mixing process as a whole, i.e. involving a complete monitoring and controlling of the mixing process during the whole mixing cycle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/31—Couplings
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/321—Disposition of the drive
    • B01F35/3211—Disposition of the drive independent from the receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F35/00—Accessories for mixers; Auxiliary operations or auxiliary devices; Parts or details of general application
    • B01F35/30—Driving arrangements; Transmissions; Couplings; Brakes
    • B01F35/32—Driving arrangements
    • B01F35/322—Construction of driving shafts
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01F—MIXING, e.g. DISSOLVING, EMULSIFYING OR DISPERSING
    • B01F2101/00—Mixing characterised by the nature of the mixed materials or by the application field
    • B01F2101/23—Mixing of laboratory samples e.g. in preparation of analysing or testing properties of materials

Definitions

  • the invention relates to a multi-function mixing device for samples in small, sealed or not closed, then open-top containers in the laboratory.
  • the cyclical flooding of solid areas in the vessels as they represent, for example cell cultures, which causes a constant refreshment of directly related to the cell culture liquid layer as well as a constant change of contact, for example, the cell culture with liquid and the gas contained in the vessel. It differs depending on the movement of the mixing devices
  • Containers Containers, rotary mixers, rolling mixers, rotary-roll mixers, tilting mixers, vibrating mixers. Ping-pong mixer, tumble mixer. In some devices, the described forms of motion can be combined. Mixers are sometimes referred to as a shaker or blender.
  • the magnetic rotating field is generated by motor-driven, rotating about a vertical axis magnets or switched by the magnetic field electric coils. These coils are fixedly arranged in a circle and are switched electronically alternately so that results in a magnetic rotating field.
  • the rotating field acts through the magnetic stirrer setting plate and, in normal use, on the stirrer or stir bar (e.g., DE 102006024300 B4).
  • EP 676234 A1 discloses a mixing device for laboratory use, which is intended for use with a drive of a magnetic stirrer.
  • the device comprises a base element and an outer element, wherein the outer element is arranged obliquely but at a fixed angle relative to the base element, and Sample tubes are inserted into a clamping device.
  • Another embodiment shows the arrangement of the outer element to the base of 90 degrees and includes a plurality of rollers which are rotatably mounted and can be placed on soft sample tubes.
  • US 3980227 A and US 5266273 A show devices with their own drive element for moving vials or cuvettes in only two selectable directions of movement, once in an inclined position for mixing the samples and on the other with a mild centrifugal force.
  • the known mixing devices are on the one hand consuming and therefore expensive, and they are not sufficiently universal. Multiple mixers, as required to achieve a variety of mixing operations required in the laboratories, are associated with not inconsiderable costs and take away much of the laborious space in laboratories. The range of adjustable mixing parameters is low.
  • the multi-function mixing device for laboratory operation is provided for samples in small, sealed or not closed, open-topped containers. It can be used in conjunction with a drive device for a magnetic stirrer or with its own drive, wherein the rotational movement of the vertical axis is converted into one or two horizontal axial rotational movements.
  • the multi-function mixer is characterized in that on the horizontal axis on one or both sides via coupling elements various auxiliary devices are arranged to perform various mixing tasks, such as turning, tilting, rocking or roll-tilting, or are coupled to further drive elements.
  • the coupling elements are constructed as detachable, in particular magnetic, angularly adjustable joints. The joints are adjustable at an angle of 0 ° to 90 °.
  • the angle-adjustable joints in the form of a bent coupling is designed, which consists of two magnets, wherein one of the magnets recessed in a bore is arranged and the other magnet protrudes from the coupling element, wherein in the coupled state of the other Magnet in the first hole holds and both magnets tighten.
  • a rocker located above the housing which is rotatably mounted about a guide axis and at the opposite end supported by a spring, consists of ferromagnetic material or has one or more magnets.
  • the horizontal axis carries in one embodiment an eccentric, which is connected via an arm and a pivot bearing in operative connection with a support plate which is rotatably supported on one side via a shaft.
  • the rotational movement of the horizontal axis is transmitted by means of a magnetic coupling to elements outside of a hermetically sealed housing, in the way that Magnets or ferromagnetic elements are connected to the gear inside the hermetically sealed housing and outside the housing a fixed, non-rotating bearing pin, which lies in the alignment of the horizontal axis, a coupling part receives, which also contains magnets or ferromagnetic elements, which upon rotation of the Gear are taken by the magnetic force effects.
  • Non-powered device without electrical connection which requires no approval and no cyclical monitoring
  • FIG. 1 shows an embodiment with screw and gear without own active drive, which takes place via the rotating magnetic field of an external magnetic stirrer
  • FIG. 2a, b two embodiments of a kinkable coupling
  • Figure 3 shows a first embodiment of a tilting or rocking mixer
  • Figure 4 shows an embodiment in which instead of the pairing worm shaft a friction gear application is used
  • Figure 5 is a clutch in the force path, the hermetically sealed housing allows
  • FIG. 6 shows a mixing device with combination drive and with a further embodiment of the tilting or tilting mixer
  • FIG. 7 shows a mixing device alone with motor drive and mounted tilting or tilting mixer
  • FIG. 8 shows a side view of the mixing device according to FIG. 7
  • FIG. 9 shows a mixing device with rocker with adhesive coating
  • FIG. 10 shows a hermetically sealed mixer (closed housing) with motor drive.
  • the multi-function mixing device can be used in connection with a drive device for a magnetic stirrer or with its own drive.
  • a vertical rotational movement is converted into one or two horizontal axial rotational movements.
  • Known means for this implementation are, for example, a worm gear and a gear, a pair of bevel gears, a friction gear or a traction mechanism.
  • FIG. 1 shows a first exemplary embodiment.
  • the housing that encloses the shafts, the worm and the gear and fix their bearing elements is not shown here.
  • the magnetic rotating field of a magnetic stirrer is generated by motor-driven, rotating about a vertical axis magnets or switched by the magnetic field electric coils. These coils are fixedly arranged in a circle and are switched electronically alternately so that results in a magnetic rotating field.
  • the rotating field acts through the adjusting plate of the magnetic stirrer, in the normal application to the Rhakfischchen.
  • a small bar 1 the magnetic carrier, has magnets 14 distributed symmetrically with respect to the central axis in a horizontal plane.
  • This beam is located close to the pitch of the magnetic stirrer and thereby approximately in the middle of the rotating magnetic field and is symmetrically connected to a vertical axis 5.
  • This vertical axis 5 has a worm, a worm gear 6, which is rotated by the rotating magnetic field.
  • This gear screw 6 is arranged such that it acts on at least one gear 7 with a horizontal axis 8 and thus rotates in its rotation, this axis 8 with high reduction and associated torque increase.
  • the horizontal axis 8 of the gear 7 may have one or more further rotation of the clutches.
  • the axis 8 may have on one or both sides coupling elements or couplings for the attachment of different brackets of the container to be mixed or further drive elements.
  • brackets can be performed very differently in a known manner, as a look in catalogs for known mixer shows.
  • Magnets can have distances, also several magnets can be mounted on different radii on the beam or the beam takes the form of a cross with two or more arms, wherein on the ends of the arms of different lengths are fixed magnets.
  • the beam consists of ferromagnetic material and only the magnets of the magnetic agitator generate the entraining forces.
  • the axle 8 has on at least one side outside its bearings 10 in itself or in a connecting element, e.g. a coupling to a kink 11, which is preferably designed as an adjustable joint, which is adjustable at an angle of 0 ° to 90 °.
  • the containers 9 (laboratory tubes, sample tubes, tubes, reaction tubes with screw cap, vials, tubes, covered multi-well plates) with the content to be mixed are connected to the part of the axis 8, for example by means of clip holders, viewed from the gear 7 from behind the kink 11 lies.
  • the kink can be designed as a detachable and lockable mechanical joint in a variety of ways.
  • a particularly favorable embodiment of the joint, which is to be referred to as articulated coupling, show the figures 2a and 2b.
  • an axis 34 around which the magnetic ring farther away from the gear can rotate. This axis can also be very short, stubby or a spherical cap.
  • the alternative embodiment (FIG. 2b) is also proposed.
  • a first magnet is recessed in a first bore and the second magnet is out of a second bore.
  • the second magnet grips into the first bore and both magnets attract, creating the clutch force.
  • the coupling effect can be supplemented by other elements such as pins and locking elements, in which this pin engages.
  • the rotation of the two coupling sides against each other allows a stepless adjustment of the bending angle in the range of 0 ° to 2 ⁇ .
  • This coupling is easily solvable by hand, for which the magnets are tilted and released in this way, so that the containers with the contents to be mixed together with their holder are removable.
  • the removal can offer advantages when loading the holders with the containers as well as when changing brackets and / or containers.
  • the magnetic rings or magnetic cylinders or elements connected to them may have on their circumference a scale, e.g. engraved or lasered, have, with the help of a desired angle is reproducibly adjustable. Magnets used here do not have to be designed as a ring. It is also proposed to actively magnetize only one side and to make the other side of a ferromagnetic material. -
  • Fig. 2b illustrates a coupling with adjustable bending angle, in which a magnet 31 itself represents the axis of rotation. Of the two round magnets 30 and 31 is one, 30, further inserted, the other, 32, something protrudes and the latter engages in the opening above the further embedded magnet.
  • the two-sided statements such as waves or mounting are connected to the coupling parts 32 and 33.
  • a catch 15 supports the transmission of torque.
  • one side of the axle can have a connected magnetic ring whose axis of symmetry lies in the direction of the straight axis 8 and thus shows a vertical surface with a bore.
  • This magnet allows the fixed coupling and release of the carrier of the container to be mixed by magnetic forces.
  • a holder can be clicked with several containers that are normally vertical and are now mixed tilting at the mixer according to the invention by the rotation of the axis 8.
  • the turn-tilt mixer according to the invention in addition to the tilting mixer.
  • a second gear which cooperates with the screw, which also has a housing mounted in the preferably horizontal axis, which preferably protrudes on the other side of the housing than the axis of the first gear. This can move more mixer tanks. On both sides of the mixer mixing vessels are then coupled.
  • FIG. 3 A possible embodiment is shown in FIG 3. Above the housing of the mixer according to the invention is a kind of rocker 20, rotatably mounted and supported at the opposite end with a spring 24.
  • This rocker 20 has approximately over the gear 7 and outside of the housing 12, a ferromagnetic material 23 or one or more magnets whose effect passes through the housing of the mixer to the outside, such that in the radial direction results in a magnetic alternating force and in the axial Direction a circumferential attractive force. If the magnet 22 connected to the toothed wheel 7 rotates, a force action between the two magnet areas which differs in intensity and with a corresponding arrangement also in the direction causes the spring to be compressed or relaxed.
  • the rocker 20 moves thereby about its guide axis 21 lying on the rocker 20 largely transversely to the guide axis containers such Tube 25, for example, in a holder 26, learn this so that an alternating tilting movement whereby their content is mixed. This gives the function of a pure tilting mixer.
  • FIG. 4 shows a friction gear.
  • the beam (magnetic carrier) 1 transmits its rotation to the vertical axis 5 and this on the small friction wheel 16.
  • the small friction wheel 16 in turn rotates the large wheel 17, which corresponds functionally to the gear 7, and by this, the horizontal axis 8 in rotation added.
  • the shaft bearings and the frame or housing have been omitted.
  • a traction mechanism is applicable, wherein the belt, preferably a round belt, a groove wheel on the vertical axis and a groove wheel on the horizontal axis comprises semicircular and two other wheels or rollers belt movement from the vertical to the horizontal and vice versa redirect familiar way.
  • the housing 12 of the mixer without any open passage, closed, also on the ground by the bottom plate 47, and the movement of the not here through the housing leading horizontal axis 8a is by means of a Magnetic coupling transmitted through the permeable to magnetic fields housing on external elements.
  • the inner, located in the housing part of the magnetic coupling is preferably through Magnets 40 or ferromagnetic elements secured to the gear 7 formed.
  • a fixed, non-rotating bearing pin 42 (in alignment with the horizontal axis 8a) receives a coupling part 43 which contains magnets or ferromagnetic elements 41, which are entrained upon rotation of the gear 7 by the magnetic force effects, whereby the outer part 43 rotates like the inner gear 7.
  • the coupling part 43 can directly carry the holder 44 of the tubes, but this can also be secured by a further non-rotating magnetic holder with a possible ferromagnetic part 45 and holding magnets 46 and the force path to the tube can also have a bent coupling 11, for example, as stated above with Figure 2, so as to make the mixer for tilting mixer. If the holder of the tubes to be changed with or without tubes, the coupling 43 is withdrawn from the pin 42 or the separation is - if so executed - also possible by lifting the magnet 46.
  • the advantage of the closed design is the good cleanability up to the possibility of sterilization. The application can thus also be carried out in safety laboratories.
  • the asymmetric structure of the mixer leads to the other
  • Proposal to use the free area of the foot, e.g. there to mount brackets, are inserted into the tubes upright.
  • a further advantageous embodiment of the rocker results from the following proposal in Fig. 6.
  • a base plate 61 of the rocker engages positively over a portion of the mixer housing.
  • An additional frictional connection is advantageously carried out by means of magnetic forces.
  • the housing and the base plate 61 magnetic and / or one-sided ferromagnetic elements 67, which are largely opposite and act on each attracting.
  • Other types of connections such as snap or clamp connections are also among the proposed connections.
  • the base plate 61 of the rocker carries receptacles for a shaft 62. About the shaft 62 is above the base plate 61 the Support plate 60 also connected to shaft receptacles with the base plate 61.
  • the support plate 60 has an arm 63 which carries at its end a pivot bearing 64, preferably a small ball bearing. This bearing sits on the Excenterrad 65.
  • the eccentric 65 is held by the horizontal shaft, the gear shaft, and driven by this. Arm and shaft have a distance that determines the movement.
  • the eccentric 65 is placed on the coupling of the horizontal shaft.
  • the plane of rotation of the Excenterrades 65 is horizontal. Due to the eccentric bearing the rotary bearing 64 undergoes a vertical movement, which transmits via the arm 63 to the support plate 60.
  • the support plate 60 On the arm 63, the support plate 60 carries out the almost vertical movement and it pivots about the axis 62, so thus performs a tilting movement about the axis 62.
  • Tubes 69 which are located in a holder 68 and lie transverse to the shaft on the support plate 60, undergo a tilting movement.
  • An eccentric wheel is preferably coupled to the clutch with magnetic forces.
  • the mixing device can, as shown in the example of Figure 6, also be carried out without being bound to a magnetic stirrer.
  • a motor 50 is inserted.
  • the motor 50 preferably a small stepping motor, advantageously has a continuous axis 53.
  • the one end of the motor shaft is inserted and fixed in the lower, for this purpose bored end of the vertical axis (the worm shaft) 5, preferably by gluing.
  • the cables of the motor 50 through which it is supplied with energy.
  • Magnetic carrier attached.
  • the magnets mounted on the beam are carried along by the rotating field and the mixer rotates. If no magnetic stirrer is available, alternatively the motor 50 can be activated.
  • the Power is supplied via a plug-in power supply whose output voltage is fed to the electronic module 51.
  • the drive can be done either by placing on an active magnetic stirrer or by a motor.
  • a further embodiment is proposed derived in which the drive takes place solely via the motor 50, FIG. 7.
  • a mixer with motor has in addition to the motor 50 a
  • the electronic module has integrated circuits, preferably a microcontroller.
  • this electronic module has further elements for inputting and / or outputting signals, eg a potentiometer for setting the speed, buttons, microphones, loudspeakers or sounders, display elements such as LEDs, IR diodes, text displays, etc.
  • a potentiometer for setting the speed
  • display elements such as LEDs, IR diodes, text displays, etc.
  • the microcontroller has a bus system such as 1-wire bus, infrared or I 2 C or RS485, via the other modular components can be coupled.
  • a programming, program selection, parameter input and output as well as the start of actions can be done via a remote control, similar to that of a television but also via a voice input.
  • FIG. 8 shows a side view of the embodiment according to FIG. 7. The explanation of FIG. 7 also applies here.
  • FIG. 9 shows an embodiment in which the support of the tube 69 consists of an adhesive film 70 (so-called magic harid).
  • the tubes, placed on this slide, are sufficiently strong here. Also conceivable is the use for sealed or covered microtiter plates.
  • FIG. 10 shows a hermetically sealed mixing device (closed
  • Base plate which closes the housing 12 of the mixer according to the invention below over the plate 4 of the magnetic stirrer
  • Motor preferably a stepper motor
  • Electronics assembly e.g. for the control of a stepper motor
  • Cable for the supply of electrical energy preferably from a power adapter

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Radar, Positioning & Navigation (AREA)
  • Mixers With Rotating Receptacles And Mixers With Vibration Mechanisms (AREA)

Abstract

L'invention concerne un mélangeur multifonction pour des applications de laboratoire, destiné à des échantillons contenus dans de petits récipients ouverts vers le haut, fermés ou non fermés. Il s'utilise conjointement avec un dispositif d'entraînement pour un agitateur magnétique ou avec un entraînement propre, la rotation de l'axe vertical (5) étant transformée en une ou deux rotations axiales horizontales. Le mélangeur multifonction est caractérisé en ce que différents dispositifs supplémentaires sont disposés sur l'axe horizontal (8), d'un côté ou des deux côtés, par l'intermédiaire d'éléments de couplage pour remplir différentes fonctions de mélange, comme tourner, basculer, battre ou rouler-basculer, ou bien en ce que des éléments d'entraînement de prolongation sont couplés. Les éléments de couplage sont de conception amovible, notamment des articulations magnétiques, d'angle réglable. Les articulations sont réglables dans un angle de 0° à 90°.
PCT/EP2010/052725 2009-03-05 2010-03-03 Mélangeur multifonction pour des applications de laboratoire Ceased WO2010100212A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102009011987A DE102009011987A1 (de) 2009-03-05 2009-03-05 Mischgerät für den Laborbetrieb
DE102009011987.6 2009-03-05

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Publication Number Publication Date
WO2010100212A1 true WO2010100212A1 (fr) 2010-09-10
WO2010100212A9 WO2010100212A9 (fr) 2011-03-31

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WO (1) WO2010100212A1 (fr)

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WO2013170691A1 (fr) * 2012-05-15 2013-11-21 深圳市飞世尔实业有限公司 Machine agitatrice magnétique à rotation et révolution dans un cercle pour la production d'une bille d'or conductrice
CN106732156A (zh) * 2016-12-13 2017-05-31 成都聚智工业设计有限公司 一种应用到变距搅拌设备的电源线供给装置
CN108905788A (zh) * 2018-06-29 2018-11-30 镇江玄润电气设备有限公司 一种腻子粉搅拌装置
WO2019018002A1 (fr) * 2017-07-18 2019-01-24 The Gid Group, Inc. Système de digestion de tissu adipeux et procédé de traitement de tissu
CN111289343A (zh) * 2020-04-04 2020-06-16 太原理工大学 一种用于离线油样的自动摇匀装置
CN113521797A (zh) * 2021-06-29 2021-10-22 百色学院 鱼腥草浸出物超声波提取工艺及提取设备及方法
DE102021113728A1 (de) 2021-05-27 2022-12-01 Ika-Werke Gmbh & Co. Kg Funktionsadapter für Magnetrührer und Magnetrühreranordnung mit einem Magnetrührer und einem Funktionsadapter
US11666605B2 (en) 2010-07-09 2023-06-06 Gid Bio, Inc. Method for preparing a product comprising stromal vascular fraction cells
US11898138B2 (en) 2013-09-05 2024-02-13 The Gid Group, Inc. Tissue processing apparatus and method for processing adipose tissue

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