WO2014147578A4 - Composés antibactériens contre des bactéries résistantes aux médicaments - Google Patents

Composés antibactériens contre des bactéries résistantes aux médicaments Download PDF

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Publication number
WO2014147578A4
WO2014147578A4 PCT/IB2014/059989 IB2014059989W WO2014147578A4 WO 2014147578 A4 WO2014147578 A4 WO 2014147578A4 IB 2014059989 W IB2014059989 W IB 2014059989W WO 2014147578 A4 WO2014147578 A4 WO 2014147578A4
Authority
WO
WIPO (PCT)
Prior art keywords
antibacterial compounds
antibacterial
caused
salts
disease
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/IB2014/059989
Other languages
English (en)
Other versions
WO2014147578A2 (fr
WO2014147578A3 (fr
Inventor
Rup LAL
Taifo Mahmud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Delhi
Department of Biotechnology of Ministry of Science and Technology India
Oregon State University
State of Oregon
Original Assignee
University of Delhi
Department of Biotechnology of Ministry of Science and Technology India
Oregon State University
State of Oregon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Delhi, Department of Biotechnology of Ministry of Science and Technology India, Oregon State University, State of Oregon filed Critical University of Delhi
Priority to CN201480029144.8A priority Critical patent/CN105228617A/zh
Priority to RU2015144539A priority patent/RU2672064C2/ru
Publication of WO2014147578A2 publication Critical patent/WO2014147578A2/fr
Publication of WO2014147578A3 publication Critical patent/WO2014147578A3/fr
Publication of WO2014147578A4 publication Critical patent/WO2014147578A4/fr
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A61K31/4162—1,2-Diazoles condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne la production d'analogues de rifamycine contre des bactéries résistantes aux médicaments. L'invention concerne également des composés antibactériens contre des mycobactéries résistantes aux médicaments. L'invention concerne également une composition pharmaceutique comprenant un composé antibactérien contre des bactéries résistantes aux médicaments, notamment des mycobactéries. L'invention concerne également l'utilisation de composés antibactériens pour le traitement d'une maladie causée par des bactéries, et notamment des mycobactéries.
PCT/IB2014/059989 2013-03-20 2014-03-20 Composés antibactériens contre des bactéries résistantes aux médicaments Ceased WO2014147578A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201480029144.8A CN105228617A (zh) 2013-03-20 2014-03-20 抗耐药性细菌的抗菌化合物
RU2015144539A RU2672064C2 (ru) 2013-03-20 2014-03-20 Антибактериальные соединения против лекарственно-устойчивых бактерий

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN690DE2013 2013-03-20
IN690/DEL/2013 2013-03-20

Publications (3)

Publication Number Publication Date
WO2014147578A2 WO2014147578A2 (fr) 2014-09-25
WO2014147578A3 WO2014147578A3 (fr) 2015-03-05
WO2014147578A4 true WO2014147578A4 (fr) 2015-04-16

Family

ID=50680079

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2014/059989 Ceased WO2014147578A2 (fr) 2013-03-20 2014-03-20 Composés antibactériens contre des bactéries résistantes aux médicaments

Country Status (3)

Country Link
CN (1) CN105228617A (fr)
RU (1) RU2672064C2 (fr)
WO (1) WO2014147578A2 (fr)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119736186A (zh) * 2024-11-27 2025-04-01 云南大学 一株拟无枝酸菌yinm00005及其在制备安莎霉素类化合物中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5985560A (en) 1997-05-08 1999-11-16 Lal; Rup Cloning vector and a process for the preparation thereof
KR100620404B1 (ko) * 2000-08-09 2006-09-13 파나세아 바이오테크 리미티드 항결핵 약물의 신규 약제학적 조성물 및 그의 제조방법
CN101395259A (zh) * 2005-12-14 2009-03-25 活跃生物药物学有限公司 利福霉素类似物及其应用
CN102357249A (zh) * 2011-10-26 2012-02-22 广州赫尔氏药物开发有限公司 能够抑制耐药性结核杆菌的药物

Also Published As

Publication number Publication date
WO2014147578A2 (fr) 2014-09-25
RU2015144539A (ru) 2017-04-20
RU2672064C2 (ru) 2018-11-09
WO2014147578A3 (fr) 2015-03-05
CN105228617A (zh) 2016-01-06

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