WO2016001450A3 - Variants de subtilase et polynucléotides codant pour ceux-ci - Google Patents

Variants de subtilase et polynucléotides codant pour ceux-ci Download PDF

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Publication number
WO2016001450A3
WO2016001450A3 PCT/EP2015/065376 EP2015065376W WO2016001450A3 WO 2016001450 A3 WO2016001450 A3 WO 2016001450A3 EP 2015065376 W EP2015065376 W EP 2015065376W WO 2016001450 A3 WO2016001450 A3 WO 2016001450A3
Authority
WO
WIPO (PCT)
Prior art keywords
variants
polynucleotides encoding
subtilase variants
encoding same
compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/EP2015/065376
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English (en)
Other versions
WO2016001450A2 (fr
Inventor
Frank Winther Rasmussen
Peter Kamp Hansen
Lars Lehmann Hylling Christensen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
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Novozymes AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=53514185&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2016001450(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to US15/323,882 priority Critical patent/US10626388B2/en
Priority to EP20173824.2A priority patent/EP3739029A1/fr
Priority to EP15734371.6A priority patent/EP3164486B1/fr
Application filed by Novozymes AS filed Critical Novozymes AS
Publication of WO2016001450A2 publication Critical patent/WO2016001450A2/fr
Publication of WO2016001450A3 publication Critical patent/WO2016001450A3/fr
Anticipated expiration legal-status Critical
Priority to US16/789,555 priority patent/US10920209B2/en
Priority to US17/143,313 priority patent/US11591586B2/en
Priority to US18/157,497 priority patent/US12065680B2/en
Priority to US18/759,529 priority patent/US20240425836A1/en
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C12N9/54—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea bacteria being Bacillus
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11D—DETERGENT COMPOSITIONS; USE OF SINGLE SUBSTANCES AS DETERGENTS; SOAP OR SOAP-MAKING; RESIN SOAPS; RECOVERY OF GLYCEROL
    • C11D3/00—Other compounding ingredients of detergent compositions covered in group C11D1/00
    • C11D3/16—Organic compounds
    • C11D3/38—Products with no well-defined composition, e.g. natural products
    • C11D3/386—Preparations containing enzymes, e.g. protease or amylase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/52—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from bacteria or Archaea
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21062—Subtilisin (3.4.21.62)

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Detergent Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

La présente invention concerne de nouveaux variants de subtilase présentant une stabilité augmentée et de préférence des performances de lavage similaires ou améliorées. Les variants de l'invention conviennent pour une utilisation, par exemple, dans des compositions de nettoyage ou détergentes, telles que des compositions détergentes pour la lessive et des compositions pour la vaisselle, comprenant des compositions pour lave-vaisselle. La présente invention porte également sur des séquences d'ADN isolées codant pour les variants, sur des vecteurs d'expression, des cellules hôtes et des procédés pour la production et l'utilisation des variants de l'invention.
PCT/EP2015/065376 2014-07-04 2015-07-06 Variants de subtilase et polynucléotides codant pour ceux-ci Ceased WO2016001450A2 (fr)

Priority Applications (7)

Application Number Priority Date Filing Date Title
US15/323,882 US10626388B2 (en) 2014-07-04 2015-07-06 Subtilase variants and polynucleotides encoding same
EP20173824.2A EP3739029A1 (fr) 2014-07-04 2015-07-06 Variants de subtilase et polynucléotides codant pour ceux-ci
EP15734371.6A EP3164486B1 (fr) 2014-07-04 2015-07-06 Variants de subtilase et polynucléotides codant pour ceux-ci
US16/789,555 US10920209B2 (en) 2014-07-04 2020-02-13 Subtilase variants having improved storage stability
US17/143,313 US11591586B2 (en) 2014-07-04 2021-01-07 Subtilase variants and polynucleotides encoding same
US18/157,497 US12065680B2 (en) 2014-07-04 2023-01-20 Subtilase variants and polynucleotides encoding same
US18/759,529 US20240425836A1 (en) 2014-07-04 2024-06-28 Subtilase variants and polynucleotides encoding same

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA201400368 2014-07-04
DKPA201400368 2014-07-04

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US15/323,882 A-371-Of-International US10626388B2 (en) 2014-07-04 2015-07-06 Subtilase variants and polynucleotides encoding same
US16/789,555 Division US10920209B2 (en) 2014-07-04 2020-02-13 Subtilase variants having improved storage stability

Publications (2)

Publication Number Publication Date
WO2016001450A2 WO2016001450A2 (fr) 2016-01-07
WO2016001450A3 true WO2016001450A3 (fr) 2016-04-14

Family

ID=53514185

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2015/065376 Ceased WO2016001450A2 (fr) 2014-07-04 2015-07-06 Variants de subtilase et polynucléotides codant pour ceux-ci

Country Status (3)

Country Link
US (5) US10626388B2 (fr)
EP (2) EP3739029A1 (fr)
WO (1) WO2016001450A2 (fr)

Families Citing this family (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106661566A (zh) * 2014-07-04 2017-05-10 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
CN107075493B (zh) * 2014-12-04 2020-09-01 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
CN108012544A (zh) * 2015-06-18 2018-05-08 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
BR112018072530A2 (pt) 2016-05-03 2019-03-26 Danisco Us Inc variantes de protease e usos das mesmas
BR112018072586A2 (pt) 2016-05-05 2019-02-19 Danisco Us Inc variantes de protease e usos das mesmas
CA3026064A1 (fr) 2016-05-31 2017-12-07 Danisco Us Inc. Variants de protease et leurs utilisations
EP3301169A1 (fr) * 2016-10-03 2018-04-04 The Procter & Gamble Company Composition de détergent pour lessive
EP4520820A3 (fr) * 2016-12-21 2025-04-16 Danisco Us Inc Variants de protéase et leurs utilisations
DK3601553T3 (da) 2017-03-31 2026-02-16 Danisco Us Inc Alfa-amylase-kombinationsvarianter
EP3668973A2 (fr) 2017-08-18 2020-06-24 Danisco US Inc. Variants d'alpha-amylases
EP3818139A1 (fr) 2018-07-02 2021-05-12 Novozymes A/S Compositions de nettoyage et leurs utilisations
US12584119B2 (en) 2018-07-31 2026-03-24 Danisco Us Inc Variant alpha-amylases having amino acid substitutions that lower the PKA of the general acid
WO2020077331A2 (fr) 2018-10-12 2020-04-16 Danisco Us Inc Alpha-amylases présentant des mutations qui améliorent la stabilité en présence de chélateurs
WO2020200198A1 (fr) * 2019-04-02 2020-10-08 Novozymes A/S Compositions de détergent liquide pour laver la vaisselle
EP4048683A2 (fr) 2019-10-24 2022-08-31 Danisco US Inc Alpha-amylases formant des variants de maltopentaose/maltohexaose
WO2023114988A2 (fr) 2021-12-16 2023-06-22 Danisco Us Inc. Alpha-amylases formant des variants de maltopentaose/maltohexaose
EP4612286A1 (fr) 2022-11-04 2025-09-10 Basf Se Polypeptides présentant une activité protéasique pour utilisation dans des compositions détergentes
EP4612285A1 (fr) 2022-11-04 2025-09-10 Basf Se Polypeptides présentant une activité protéasique pour utilisation dans des compositions détergentes
WO2024094735A1 (fr) 2022-11-04 2024-05-10 Basf Se Polypeptides présentant une activité protéasique pour utilisation dans des compositions détergentes
WO2025202370A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
WO2025202379A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
WO2025202374A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
WO2025202369A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
EP4624572A1 (fr) 2024-03-27 2025-10-01 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
WO2025202382A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions de nettoyage
WO2025202372A1 (fr) 2024-03-27 2025-10-02 Basf Se Polypeptides ayant une activité protéase destinés à être utilisés dans des compositions détergentes
WO2026024921A1 (fr) * 2024-07-25 2026-01-29 The Procter & Gamble Company Composition détergente comprenant un variant de subtilisine et procédés d'utilisation
WO2026046881A1 (fr) 2024-08-26 2026-03-05 Novozymes A/S Compositions comprenant une hexosaminidase et une protéase

Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988008033A1 (fr) * 1987-04-10 1988-10-20 Amgen Inc. Analogues de subtilisine
WO1995010591A1 (fr) * 1993-10-14 1995-04-20 The Procter & Gamble Company Compositions de nettoyage contenant une protease
WO1998020116A1 (fr) * 1996-11-04 1998-05-14 Novo Nordisk A/S Variants de subtilase et compositions
WO1999020726A1 (fr) * 1997-10-23 1999-04-29 The Procter & Gamble Company Compositions de blanchiment comprenant des variantes de protease multisubstituees
US6555355B1 (en) * 1997-08-29 2003-04-29 Novozymes, A/S Protease variants and compositions
EP1403282A1 (fr) * 2002-09-26 2004-03-31 Cellzome Ag Complexes de protéines de la voie de signalisation du facteur de nécrose tumorale-alpha (TNF-alpha)
WO2004041979A2 (fr) * 2002-11-06 2004-05-21 Novozymes A/S Variantes de subtilase
US6831053B1 (en) * 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
WO2009149200A2 (fr) * 2008-06-06 2009-12-10 Danisco Us Inc. Compositions et procédés comprenant des protéases microbiennes variantes
US20100192985A1 (en) * 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants
WO2010123754A1 (fr) * 2009-04-24 2010-10-28 Danisco Us Inc. Protéases avec des régions pro modifiées
US20130260438A1 (en) * 2010-05-06 2013-10-03 Danisco Us Inc. Compositions and methods comprising serine protease variants (as amended)

Family Cites Families (259)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1296839A (fr) 1969-05-29 1972-11-22
GB1483591A (en) 1973-07-23 1977-08-24 Novo Industri As Process for coating water soluble or water dispersible particles by means of the fluid bed technique
GB1590432A (en) 1976-07-07 1981-06-03 Novo Industri As Process for the production of an enzyme granulate and the enzyme granuate thus produced
DK187280A (da) 1980-04-30 1981-10-31 Novo Industri As Ruhedsreducerende middel til et fuldvaskemiddel fuldvaskemiddel og fuldvaskemetode
US5185258A (en) 1984-05-29 1993-02-09 Genencor International, Inc. Subtilisin mutants
DK263584D0 (da) 1984-05-29 1984-05-29 Novo Industri As Enzymholdige granulater anvendt som detergentadditiver
JPH0697997B2 (ja) 1985-08-09 1994-12-07 ギスト ブロカデス ナ−ムロ−ゼ フエンノ−トチヤツプ 新規の酵素的洗浄剤添加物
EG18543A (en) 1986-02-20 1993-07-30 Albright & Wilson Protected enzyme systems
ATE110768T1 (de) 1986-08-29 1994-09-15 Novo Nordisk As Enzymhaltiger reinigungsmittelzusatz.
US5389536A (en) 1986-11-19 1995-02-14 Genencor, Inc. Lipase from Pseudomonas mendocina having cutinase activity
DE3854249T2 (de) 1987-08-28 1996-02-29 Novonordisk As Rekombinante Humicola-Lipase und Verfahren zur Herstellung von rekombinanten Humicola-Lipasen.
DK6488D0 (da) 1988-01-07 1988-01-07 Novo Industri As Enzymer
EP0471265B1 (fr) 1988-01-07 1995-10-25 Novo Nordisk A/S Protéase spécifique
JP3079276B2 (ja) 1988-02-28 2000-08-21 天野製薬株式会社 組換え体ｄｎａ、それを含むシュードモナス属菌及びそれを用いたリパーゼの製造法
WO1989009259A1 (fr) 1988-03-24 1989-10-05 Novo-Nordisk A/S Preparation de cellulase
US5776757A (en) 1988-03-24 1998-07-07 Novo Nordisk A/S Fungal cellulase composition containing alkaline CMC-endoglucanase and essentially no cellobiohydrolase and method of making thereof
US5223409A (en) 1988-09-02 1993-06-29 Protein Engineering Corp. Directed evolution of novel binding proteins
DK316989D0 (da) * 1989-06-26 1989-06-26 Novo Nordisk As Enzymer
GB8915658D0 (en) 1989-07-07 1989-08-23 Unilever Plc Enzymes,their production and use
JP3220137B2 (ja) 1989-08-25 2001-10-22 ヘンケル・リサーチ・コーポレイション アルカリ性タンパク質分解酵素およびその製造方法
CA2082279C (fr) 1990-05-09 2007-09-04 Grethe Rasmussen Preparation de cellulase renfermant une endoglucanase
DK115890D0 (da) 1990-05-09 1990-05-09 Novo Nordisk As Enzym
DE69129988T2 (de) 1990-09-13 1999-03-18 Novo Nordisk A/S, Bagsvaerd Lipase-varianten
IL99552A0 (en) 1990-09-28 1992-08-18 Ixsys Inc Compositions containing procaryotic cells,a kit for the preparation of vectors useful for the coexpression of two or more dna sequences and methods for the use thereof
DE69133035T2 (de) 1991-01-16 2003-02-13 The Procter & Gamble Company, Cincinnati Kompakte Waschmittelzusammensetzungen mit hochaktiven Cellulasen
US5292796A (en) 1991-04-02 1994-03-08 Minnesota Mining And Manufacturing Company Urea-aldehyde condensates and melamine derivatives comprising fluorochemical oligomers
EP0511456A1 (fr) 1991-04-30 1992-11-04 The Procter & Gamble Company Détergents liquides contenant un ester aromatique de l'acide borique pour inhibition d'enzyme protéolitique
DK0583420T3 (da) 1991-04-30 1996-07-29 Procter & Gamble Builderholdige flydende detergenter med borsyre-polyol-kompleks til inhibering af proteolytisk enzym
KR100258460B1 (ko) 1991-05-01 2000-06-01 한센 핀 베네드 안정화 효소 및 세제 조성물
US5340735A (en) 1991-05-29 1994-08-23 Cognis, Inc. Bacillus lentus alkaline protease variants with increased stability
CA2124787C (fr) 1991-12-13 1998-10-27 Frederick E. Hardy Citrates acyles, esters precurseurs de peracides
DK28792D0 (da) 1992-03-04 1992-03-04 Novo Nordisk As Nyt enzym
DK72992D0 (da) 1992-06-01 1992-06-01 Novo Nordisk As Enzym
DK88892D0 (da) 1992-07-06 1992-07-06 Novo Nordisk As Forbindelse
EP0651794B1 (fr) 1992-07-23 2009-09-30 Novozymes A/S Alpha-amylase mutante, detergent et agent de lavage de vaisselle
EP1431389A3 (fr) 1992-10-06 2004-06-30 Novozymes A/S Variants de cellulases
CZ293163B6 (cs) 1993-02-11 2004-02-18 Genencor International, Inc. Mutanta alfa-amylázy, její použití, kódová DNA pro tuto mutantu, vektor pro expresi, hostitelské buňky, čisticí prostředek a prostředek pro zkapalnění škrobu
ATE287946T1 (de) 1993-04-27 2005-02-15 Genencor Int Neuartige lipasevarianten zur verwendung in reinigungsmitteln
DK52393D0 (fr) 1993-05-05 1993-05-05 Novo Nordisk As
FR2704860B1 (fr) 1993-05-05 1995-07-13 Pasteur Institut Sequences de nucleotides du locus cryiiia pour le controle de l'expression de sequences d'adn dans un hote cellulaire.
JP2859520B2 (ja) 1993-08-30 1999-02-17 ノボ ノルディスク アクティーゼルスカブ リパーゼ及びそれを生産する微生物及びリパーゼ製造方法及びリパーゼ含有洗剤組成物
CN1189558C (zh) 1993-10-08 2005-02-16 诺沃奇梅兹有限公司 淀粉酶变体
EP0724631A1 (fr) 1993-10-13 1996-08-07 Novo Nordisk A/S Variants de peroxydase stables par rapport a h 2?o 2?
MA23346A1 (fr) * 1993-10-14 1995-04-01 Genencor Int Variantes de la subtilisine
JPH07143883A (ja) 1993-11-24 1995-06-06 Showa Denko Kk リパーゼ遺伝子及び変異体リパーゼ
DE4343591A1 (de) 1993-12-21 1995-06-22 Evotec Biosystems Gmbh Verfahren zum evolutiven Design und Synthese funktionaler Polymere auf der Basis von Formenelementen und Formencodes
US5605793A (en) 1994-02-17 1997-02-25 Affymax Technologies N.V. Methods for in vitro recombination
EP0746618B1 (fr) 1994-02-22 2002-08-21 Novozymes A/S Procede pour preparer un variant d'une enzyme lipolytique
WO1995023221A1 (fr) 1994-02-24 1995-08-31 Cognis, Inc. Enzymes ameliorees et detergents les contenant
WO1995024471A1 (fr) 1994-03-08 1995-09-14 Novo Nordisk A/S Nouvelles cellulases alcalines
JP3851656B2 (ja) 1994-05-04 2006-11-29 ジェネンコア インターナショナル インコーポレーテッド 改善された界面活性剤耐性を有するリパーゼ
WO1995033836A1 (fr) 1994-06-03 1995-12-14 Novo Nordisk Biotech, Inc. Phosphonyldipeptides efficaces dans le traitement de maladies cardiovasculaires
WO1995035381A1 (fr) 1994-06-20 1995-12-28 Unilever N.V. Lipases modifiees provenant de pseudomonas et leur utilisation
WO1996000292A1 (fr) 1994-06-23 1996-01-04 Unilever N.V. Pseudomonas lipases modifiees et leur utilisation
DE69535733T2 (de) 1994-10-06 2009-04-23 Novozymes A/S Ein enzympräparat mit endoglucanase aktivität
BE1008998A3 (fr) 1994-10-14 1996-10-01 Solvay Lipase, microorganisme la produisant, procede de preparation de cette lipase et utilisations de celle-ci.
BR9509525A (pt) 1994-10-26 1995-10-26 Novo Nordisk As Construção de dna vetor de expressão recombinante célula processo para produzir a enzima que exibe atividade lipolítica enzima que exibe atividade lipolítica preparação de enzima aditivo de detergente e composição de detergente
AR000862A1 (es) 1995-02-03 1997-08-06 Novozymes As Variantes de una ó-amilasa madre, un metodo para producir la misma, una estructura de adn y un vector de expresion, una celula transformada por dichaestructura de adn y vector, un aditivo para detergente, composicion detergente, una composicion para lavado de ropa y una composicion para la eliminacion del
JPH08228778A (ja) 1995-02-27 1996-09-10 Showa Denko Kk 新規なリパーゼ遺伝子及びそれを用いたリパーゼの製造方法
EP0815209B2 (fr) 1995-03-17 2015-02-25 Novozymes A/S Nouvelles endoglucanases
ATE429490T1 (de) 1995-05-05 2009-05-15 Novozymes As Protease-varianten und verbindungen
AU6414196A (en) 1995-07-14 1997-02-18 Novo Nordisk A/S A modified enzyme with lipolytic activity
WO1997007202A1 (fr) 1995-08-11 1997-02-27 Novo Nordisk A/S Nouvelles enzymes lipolytiques
AU6513096A (en) 1995-07-19 1997-02-18 Novo Nordisk A/S Treatment of fabrics
DE19528059A1 (de) 1995-07-31 1997-02-06 Bayer Ag Wasch- und Reinigungsmittel mit Iminodisuccinaten
US5763385A (en) 1996-05-14 1998-06-09 Genencor International, Inc. Modified α-amylases having altered calcium binding properties
AU3938997A (en) 1996-08-26 1998-03-19 Novo Nordisk A/S A novel endoglucanase
BR9711479B1 (pt) 1996-09-17 2009-08-11 variante de celulase tendo uma resistência aumentada a tensìdeo de ánion.
DE69717133T2 (de) 1996-09-24 2003-07-10 The Procter & Gamble Company, Cincinnati Flüssige reinigungsmittel, die proteolytisches enzyme, peptidaldehyd und kalziumionen enthalten
CA2265734A1 (fr) 1996-10-08 1998-04-16 Novo Nordisk A/S Derives de l'acide diaminobenzoique en tant que precurseurs de matieres tinctoriales
BR9712360A (pt) 1996-10-18 2001-06-19 Procter & Gamble Composições detergentes
BR9712473B1 (pt) 1996-11-04 2009-08-11 variantes de subtilase e composições.
AR017331A1 (es) 1997-10-13 2001-09-05 Novozymes As Polipeptidos mutantes de alfa-amilasas, aditivo para detergentes y composiciones detergentes que los comprenden.
US5955310A (en) 1998-02-26 1999-09-21 Novo Nordisk Biotech, Inc. Methods for producing a polypeptide in a bacillus cell
US6838269B1 (en) 1998-04-15 2005-01-04 Genencor International, Inc. Proteins producing an altered immunogenic response and methods of making and using the same
US6472364B1 (en) 1998-10-13 2002-10-29 The Procter & Gamble Company Detergent compositions or components
JP4615723B2 (ja) 1998-12-04 2011-01-19 ノボザイムス アクティーゼルスカブ クチナーゼ変異体
US6939702B1 (en) 1999-03-31 2005-09-06 Novozymes A/S Lipase variant
EP2206786A1 (fr) 1999-08-31 2010-07-14 Novozymes A/S Nouvelles protéases et variantes associées
CA2394971C (fr) 1999-12-15 2016-01-19 Novozymes A/S Variants de subtilase a performance de nettoyage amelioree sur des taches d'oeuf
AU2001240473A1 (en) 2000-03-08 2001-09-17 Novozymes A/S Variants with altered properties
JP4988124B2 (ja) 2000-06-02 2012-08-01 ノボザイムス アクティーゼルスカブ クチナーゼ変異体
EP1370648A2 (fr) 2000-08-01 2003-12-17 Novozymes A/S Mutants d'alpha-amylase a proprietes modifiees
CN1337553A (zh) 2000-08-05 2002-02-27 李海泉 地下观光游乐园
WO2002016547A2 (fr) 2000-08-21 2002-02-28 Novozymes A/S Enzymes subtilases
AU2302002A (en) 2000-11-27 2002-06-03 Novozymes As Automated mechanical stress assay for screening cleaning ingredients
AU2002311012A1 (en) 2001-06-06 2002-12-16 Novozymes A/S Endo-beta-1,4-glucanase from bacillus
DK200101090A (da) 2001-07-12 2001-08-16 Novozymes As Subtilase variants
EP1421187B1 (fr) 2001-07-27 2007-10-10 THE GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES Systemes utilisant des oligonucleotides pour une mutagenese dirigee in vivo
DE10153792A1 (de) 2001-10-31 2003-05-22 Henkel Kgaa Neue Alkalische Protease-Varianten und Wasch- und Reinigungsmittel enthaltend diese neuen Alkalischen Protease-Varianten
GB0127036D0 (en) 2001-11-09 2002-01-02 Unilever Plc Polymers for laundry applications
DE10162728A1 (de) 2001-12-20 2003-07-10 Henkel Kgaa Neue Alkalische Protease aus Bacillus gibsonii (DSM 14393) und Wasch-und Reinigungsmittel enthaltend diese neue Alkalische Protease
EP1382668B1 (fr) 2002-06-11 2009-08-12 Unilever N.V. Tablettes détergentes
WO2004003186A2 (fr) 2002-06-26 2004-01-08 Novozymes A/S Subtilases et variants de la subtilase presentant une immunogenicite modifiee
CN1751116A (zh) 2003-02-18 2006-03-22 诺和酶股份有限公司 洗涤剂组合物
GB0314211D0 (en) 2003-06-18 2003-07-23 Unilever Plc Laundry treatment compositions
WO2005003275A1 (fr) 2003-06-18 2005-01-13 Unilever Plc Compositions de traitement pour blanchisserie
GB0314210D0 (en) 2003-06-18 2003-07-23 Unilever Plc Laundry treatment compositions
WO2005040372A1 (fr) 2003-10-23 2005-05-06 Novozymes A/S Protease a stabilite amelioree dans les detergents
WO2005052146A2 (fr) 2003-11-19 2005-06-09 Genencor International, Inc. Serine proteases, acides nucleiques codants pour les enzymes a serine et vecteurs et cellules hotes les contenant
EP2292743B1 (fr) 2003-12-03 2013-08-21 Danisco US Inc. Perhydrolase
WO2005105826A1 (fr) 2004-04-28 2005-11-10 Zaidan Hojin Biseibutsu Kagaku Kenkyu Kai Tyropeptin analogue a
MX2007007494A (es) 2004-12-23 2007-08-15 Novozymes As Variantes de alfa-amilasa.
ES2313539T3 (es) 2005-03-23 2009-03-01 Unilever N.V. Composiciones de detergente en forma de pastillas.
DE502006008083D1 (de) 2005-04-15 2010-11-25 Basf Se Amphiphile wasserlösliche alkoxylierte polyalkylenimine mit einem inneren polyethylenoxidblock und einem äusseren polypropylenoxidblock
ES2353719T3 (es) 2005-04-15 2011-03-04 The Procter And Gamble Company Composición detergente líquida para lavado de ropa con polímeros de polietilenimina modificados y enzima lipasa.
CA2605451A1 (fr) 2005-05-31 2006-12-07 The Procter & Gamble Company Compositions detergentes renfermant un polymere et leur utilisation
ES2397718T3 (es) 2005-06-17 2013-03-11 The Procter & Gamble Company Catalizador orgánico con mayor compatibilidad enzimática
JP2009500023A (ja) * 2005-07-08 2009-01-08 ノボザイムス アクティーゼルスカブ サブチラーゼ変異体
KR20080066921A (ko) 2005-10-12 2008-07-17 제넨코 인터내셔날 인코포레이티드 저장-안정성 중성 메탈로프로테아제의 용도 및 제조
US8518675B2 (en) 2005-12-13 2013-08-27 E. I. Du Pont De Nemours And Company Production of peracids using an enzyme having perhydrolysis activity
US8022027B2 (en) 2006-01-23 2011-09-20 The Procter & Gamble Company Composition comprising a lipase and a bleach catalyst
EP2248882A1 (fr) 2006-01-23 2010-11-10 The Procter and Gamble Company Composition de lavage contenant une enzyme et un agent de nuançage
RU2479627C2 (ru) 2006-01-23 2013-04-20 Дзе Проктер Энд Гэмбл Компани Композиции моющих средств
US20070191247A1 (en) 2006-01-23 2007-08-16 The Procter & Gamble Company Detergent compositions
US8187854B2 (en) 2006-01-23 2012-05-29 Novozymes A/S Lipase variants
CA2635947A1 (fr) 2006-01-23 2007-08-02 The Procter & Gamble Company Compositions contenant une enzyme et un agent de photoblanchiment
AR059154A1 (es) 2006-01-23 2008-03-12 Procter & Gamble Una composicion que comprende una lipasa y un catalizador de blanqueador
BRPI0712159B1 (pt) 2006-05-31 2018-04-24 Basf Se Polímero de enxerto anfifílico, e, processo para preparar polímeros de enxerto
DE202006009003U1 (de) 2006-06-06 2007-10-25 BROSE SCHLIEßSYSTEME GMBH & CO. KG Kraftfahrzeugschloß
EP1876226B1 (fr) 2006-07-07 2011-03-23 The Procter & Gamble Company Compositions de lavage
EP2155869A2 (fr) 2007-05-30 2010-02-24 Danisco US, INC., Genencor Division Variants d'une alpha-amylase avec des taux de production améliorés dans les processus de fermentation
TR201810838T4 (tr) 2007-06-22 2018-08-27 Unilever Nv Granüllü enzimatik deterjan bileşimleri.
PL2014756T3 (pl) 2007-07-02 2011-09-30 Procter & Gamble Kompozycja piorąca woreczka wieloprzegródkowego
GB0712988D0 (en) 2007-07-05 2007-08-15 Reckitt Benckiser Nv Improvements in or relating to compositions
GB0712991D0 (en) 2007-07-05 2007-08-15 Reckitt Benckiser Nv Improvement in or relating to compositions
EP2167624B1 (fr) 2007-07-16 2010-12-01 Unilever PLC Composition détergente solide
DE102007036392A1 (de) 2007-07-31 2009-02-05 Henkel Ag & Co. Kgaa Zusammensetzungen enthaltend Perhydrolasen und Alkylenglykoldiacetate
DE102007038029A1 (de) 2007-08-10 2009-02-12 Henkel Ag & Co. Kgaa Wasch- oder Reinigungsmittel mit polyesterbasiertem Soil-Release-Polymer
DE102007038031A1 (de) 2007-08-10 2009-06-04 Henkel Ag & Co. Kgaa Mittel enthaltend Proteasen
BRPI0815363A2 (pt) 2007-08-14 2015-02-10 Unilever Nv Detergente em tablete não-compactado de múltiplas regiões, processos de produção do mesmo, e método para limpar tecidos
GB0716228D0 (en) 2007-08-20 2007-09-26 Reckitt Benckiser Nv Detergent composition
DE102007041754A1 (de) 2007-09-04 2009-03-05 Henkel Ag & Co. Kgaa Polycyclische Verbindungen als Enzymstabilisatoren
GB0718777D0 (en) 2007-09-26 2007-11-07 Reckitt Benckiser Nv Composition
GB0718944D0 (en) 2007-09-28 2007-11-07 Reckitt Benckiser Nv Detergent composition
ES2598487T3 (es) 2007-10-12 2017-01-27 Unilever N.V. Ingredientes de rendimiento en partículas de película
EP2195409B1 (fr) 2007-10-12 2011-11-02 Unilever PLC Signes visuels améliorés destinés à des détergents pour lessive parfumés
ATE531787T1 (de) 2007-10-12 2011-11-15 Unilever Nv Waschmittel mit vorbehandlungsadditiv und seine verwendung
WO2009047127A1 (fr) 2007-10-12 2009-04-16 Unilever Plc Compositions détergentes granulaires comportant des repères visuels lamellaires contrastés
WO2009050026A2 (fr) 2007-10-17 2009-04-23 Unilever Nv Compositions de blanchisserie
KR20100088675A (ko) 2007-11-05 2010-08-10 다니스코 유에스 인크. 변경된 특성을 지닌 바실러스 종 ｔｓ-23 알파-아밀라아제의 변이체
WO2009063355A1 (fr) 2007-11-13 2009-05-22 The Procter & Gamble Company Procédé pour créer un produit en dose unitaire au moyen d'un matériau imprimé soluble dans l'eau
DE102007056166A1 (de) 2007-11-21 2009-05-28 Henkel Ag & Co. Kgaa Granulat eines sensitiven Wasch- oder Reinigungsmittelinhaltsstoffs
DE102007057583A1 (de) 2007-11-28 2009-06-04 Henkel Ag & Co. Kgaa Waschmittel mit stabilisierten Enzymen
EP2067847B1 (fr) 2007-12-05 2012-03-21 The Procter & Gamble Company Emballage comportant un détergent
DE102007059677A1 (de) 2007-12-10 2009-06-25 Henkel Ag & Co. Kgaa Reinigungsmittel
DE102007059970A1 (de) 2007-12-11 2009-09-10 Henkel Ag & Co. Kgaa Reinigungsmittel
JP5524077B2 (ja) 2008-01-04 2014-06-18 ザ プロクター アンド ギャンブル カンパニー グリコシル加水分解酵素を含む洗濯洗剤組成物
CN101910396B (zh) 2008-01-10 2012-10-17 荷兰联合利华有限公司 颗粒
PT2245129E (pt) 2008-01-24 2012-07-30 Unilever Nv Composições de detergente para máquinas de lavar loiça
WO2009095645A1 (fr) 2008-01-28 2009-08-06 Reckitt Benckiser N.V. Composition
US20090209447A1 (en) 2008-02-15 2009-08-20 Michelle Meek Cleaning compositions
AR070490A1 (es) 2008-02-29 2010-04-07 Novozymes As Polipeptidos de thermomyces lanuginosus con actividad de lipasa y polinucleotidos que los codifican
WO2009112296A1 (fr) 2008-03-14 2009-09-17 Unilever Plc Compositions de traitement du linge
CN101970632B (zh) 2008-03-14 2012-11-07 荷兰联合利华有限公司 包括聚合润滑剂的洗衣处理组合物
EP2103676A1 (fr) 2008-03-18 2009-09-23 The Procter and Gamble Company Composition détergente pour le lavage du linge comprenant un sel de magnésium d'acide diamine-n'n' disuccinique d'éthylène
DE102008014759A1 (de) 2008-03-18 2009-09-24 Henkel Ag & Co. Kgaa Verwendung von Imidazolium-Salzen in Wasch- und Reinigungsmitteln
EP2103675A1 (fr) 2008-03-18 2009-09-23 The Procter and Gamble Company Composition détergente comprenant un polymère cellulosique
EP2103678A1 (fr) 2008-03-18 2009-09-23 The Procter and Gamble Company Composition détergente comprenant un co-polyester d'acides dicarboxyliques et de diols
DE102008014760A1 (de) 2008-03-18 2009-09-24 Henkel Ag & Co. Kgaa Imidazolium-Salze als Enzymstabilisatoren
EP2271660B1 (fr) 2008-03-26 2020-05-06 Novozymes A/S Compositions enzymatique liquides stabilisées
PT3061744T (pt) 2008-04-01 2018-06-19 Unilever Nv Preparação de grânulos de fluxo livre de ácido metilglicina diacético
GB0805908D0 (en) 2008-04-01 2008-05-07 Reckitt Benckiser Inc Laundry treatment compositions
DE102008017103A1 (de) 2008-04-02 2009-10-08 Henkel Ag & Co. Kgaa Wasch- und Reinigungsmittel enthaltend Proteasen aus Xanthomonas
EP2107106A1 (fr) 2008-04-02 2009-10-07 The Procter and Gamble Company Kit de pièces comportant une composition de détergent solide pour lessive et dispositif de dosage
ES2647500T3 (es) 2008-04-02 2017-12-21 The Procter & Gamble Company Composición detergente que comprende tensioactivo detersivo no iónico y tinte reactivo
EP2107105B1 (fr) 2008-04-02 2013-08-07 The Procter and Gamble Company Composition de détergent comportant un colorant réactif
US20090253602A1 (en) 2008-04-04 2009-10-08 Conopco, Inc. D/B/A Unilever Novel personal wash bar
ES2400204T5 (es) 2008-05-02 2015-11-26 Unilever N.V. Gránulos con manchado reducido
WO2010000636A1 (fr) 2008-07-03 2010-01-07 Henkel Ag & Co. Kgaa Composition solide contenant un polysaccharide et destinée à l'entretien des textiles
BRPI0914211A2 (pt) 2008-07-09 2015-11-03 Unilever Nv processo de produção do grânulo de alginato, grânulo de alginato obtido, uso do mesmo e, composição detergente para a lavagem de tecidos
ES2400781T3 (es) 2008-07-11 2013-04-12 Unilever N.V. Copolímeros y composiciones de detergente
EP2154235A1 (fr) 2008-07-28 2010-02-17 The Procter and Gamble Company Procédé pour préparer une composition détergente
EP2154233B1 (fr) 2008-08-14 2010-09-22 Unilever N.V. Composition d'adjuvant
EP2163606A1 (fr) 2008-08-27 2010-03-17 The Procter and Gamble Company Composition de détergent comportant de l'oxydase de gluco-oligosaccharide
CA2734880A1 (fr) 2008-09-01 2010-03-04 The Procter & Gamble Company Detergent a lessive ou composition nettoyante comprenant un groupe polymere hydrophobe et son procede de production
CN102439126A (zh) 2008-09-01 2012-05-02 宝洁公司 聚合物组合物及其制备方法
WO2010024470A1 (fr) 2008-09-01 2010-03-04 The Procter & Gamble Company Composition comprenant une composition polymère à base de polyoxyalkylène
EP2163608A1 (fr) 2008-09-12 2010-03-17 The Procter & Gamble Company Particule pour composition de lavage comprenant un colorant azurant et du savon
EP2166077A1 (fr) 2008-09-12 2010-03-24 The Procter and Gamble Company Particules contenant un azurant optique
EP2166078B1 (fr) 2008-09-12 2018-11-21 The Procter & Gamble Company Particule pour composition de lavage comprenant un colorant azurant
DE102008047941A1 (de) 2008-09-18 2010-03-25 Henkel Ag & Co. Kgaa Bleichmittel-haltiges Reinigungsmittel
WO2010033747A1 (fr) 2008-09-19 2010-03-25 The Procter & Gamble Company Biopolymère à double nature utile dans les produits de nettoyage
EP2324106A1 (fr) 2008-09-19 2011-05-25 The Procter & Gamble Company Composition détergente comprenant un biopolymère modifié de stabilisation et de renforcement d eau savonneuse
BRPI0919349A2 (pt) 2008-09-22 2015-12-29 Procter & Gamble aldeídos ramificados específicos alcoóis, tensoativos e produtos á base dos mesmos destinados ao consumidor.
PL2350249T3 (pl) 2008-10-31 2014-09-30 Henkel Ag & Co Kgaa Środek do maszynowego zmywania naczyń
MX2011004803A (es) 2008-11-11 2011-06-16 Danisco Inc Composiciones y metodos que comprenden una variante de subtilisina.
WO2010054986A1 (fr) 2008-11-12 2010-05-20 Unilever Plc Système de mesure de la blancheur d’un tissu
WO2010057784A1 (fr) 2008-11-20 2010-05-27 Unilever Plc Système de mesure de la blancheur d’un tissu
DE102008059447A1 (de) 2008-11-27 2010-06-02 Henkel Ag & Co. Kgaa Wasch- und Reinigungsmittel enthaltend Proteasen aus Bacillus pumilus
US20110281324A1 (en) 2008-12-01 2011-11-17 Danisco Us Inc. Enzymes With Lipase Activity
DE102008060469A1 (de) 2008-12-05 2010-06-10 Henkel Ag & Co. Kgaa Maschinelle Geschirrspülmitteltablette
DE102008060886A1 (de) 2008-12-09 2010-06-10 Henkel Ag & Co. Kgaa Photolabile Duftspeicherstoffe
WO2010066631A1 (fr) 2008-12-12 2010-06-17 Henkel Ag & Co. Kgaa Article de blanchissage comportant des propriétés de nettoyage et de traitement
WO2010066632A1 (fr) 2008-12-12 2010-06-17 Henkel Ag & Co. Kgaa Article de blanchissage comportant des propriétés de nettoyage et de traitement
DE102008061859A1 (de) 2008-12-15 2010-06-17 Henkel Ag & Co. Kgaa Maschinelles Geschirrspülmittel
DE102008061858A1 (de) 2008-12-15 2010-06-17 Henkel Ag & Co. Kgaa Maschinelles Geschirrspülmittel
CN102257113B (zh) 2008-12-16 2013-05-08 荷兰联合利华有限公司 固体助洗剂组合物
ES2731593T3 (es) 2008-12-17 2019-11-18 Unilever Nv Composición de detergente para lavado de ropa
WO2010069742A1 (fr) 2008-12-18 2010-06-24 Unilever Nv Composition de détergent de lessive
DE102008063801A1 (de) 2008-12-19 2010-06-24 Henkel Ag & Co. Kgaa Maschinelles Geschirrspülmittel
DE102008063070A1 (de) 2008-12-23 2010-07-01 Henkel Ag & Co. Kgaa Verwendung sternförmiger Polymere mit peripheren negativ geladenen Gruppen und/oder peripheren Silyl-Gruppen zur Ausrüstung von Oberflächen
BRPI0923795B1 (pt) 2008-12-29 2017-02-21 Unilever Nv composição detergente aquosa estruturada e processo de produção da mesma
DE102009004524A1 (de) 2009-01-09 2010-07-15 Henkel Ag & Co. Kgaa Farbschützendes maschinelles Geschirrspülmittel
DE102009000409A1 (de) 2009-01-26 2010-07-29 Henkel Ag & Co. Kgaa Waschzusatzartikel
ES2413054T3 (es) 2009-01-26 2013-07-15 Unilever Nv Incorporación de colorante en composición granular de lavandería
EP2216393B1 (fr) 2009-02-09 2024-04-24 The Procter & Gamble Company Composition de détergent
WO2010094356A1 (fr) 2009-02-18 2010-08-26 Henkel Ag & Co. Kgaa Composés copolymères pro-parfum
EP2403931B1 (fr) 2009-03-05 2014-03-19 Unilever PLC Initiateurs radicalaires de colorant
MX2011008656A (es) 2009-03-06 2011-09-06 Huntsman Adv Mat Switzerland Metodos de decoloracion-blanqueo enzimatico de textiles.
BRPI1009263A2 (pt) 2009-03-10 2015-10-06 Danisco Us Inc alfa-amilases relacionadas com cepa de bacillus megaterium dsm90 e métodos de uso das mesmas.
EP2406327B1 (fr) 2009-03-12 2013-08-14 Unilever PLC Formules de polymères colorants
US20100229312A1 (en) 2009-03-16 2010-09-16 De Buzzaccarini Francesco Cleaning method
US8153574B2 (en) 2009-03-18 2012-04-10 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene polyol acetal derivatives and detersive enzymes
US8293697B2 (en) 2009-03-18 2012-10-23 The Procter & Gamble Company Structured fluid detergent compositions comprising dibenzylidene sorbitol acetal derivatives
US20120028318A1 (en) 2009-03-18 2012-02-02 Danisco Us Inc. Fungal cutinase from magnaporthe grisea
DE102009001691A1 (de) 2009-03-20 2010-09-23 Henkel Ag & Co. Kgaa Wasch- oder Reinigungsmittel mit gegebenenfalls in situ erzeugtem bleichverstärkendem Übergangsmetallkomplex
DE102009001693A1 (de) 2009-03-20 2010-09-23 Henkel Ag & Co. Kgaa 4-Aminopyridin-Derivate als Katalysatoren für die Spaltung organischer Ester
DE102009001692A1 (de) 2009-03-20 2010-09-23 Henkel Ag & Co. Kgaa Wasch- oder Reinigungsmittel mit gegebenenfalls in situ erzeugtem bleichverstärkendem Übergangsmetallkomplex
EP2411510A2 (fr) 2009-03-23 2012-02-01 Danisco US Inc. Acyltransférases associées à cal a et leurs procédés d'utilisation
EP2233557A1 (fr) 2009-03-26 2010-09-29 The Procter & Gamble Company Parfum encapsulé, composition détergente pour le lavage du linge comprenant du parfum encapsulé et procédé pour la préparation de parfum encapsulé
DE102009002262A1 (de) 2009-04-07 2010-10-14 Henkel Ag & Co. Kgaa Präbiotische Handgeschirrspülmittel
DE102009002384A1 (de) 2009-04-15 2010-10-21 Henkel Ag & Co. Kgaa Granulares Wasch-, Reinigungs- oder Behandlungsmitteladditiv
US8263543B2 (en) 2009-04-17 2012-09-11 The Procter & Gamble Company Fabric care compositions comprising organosiloxane polymers
WO2010122051A1 (fr) 2009-04-24 2010-10-28 Unilever Plc Particules de détergent hautement actives
ES2642318T3 (es) 2009-05-19 2017-11-16 The Procter & Gamble Company Un método para imprimir película soluble en agua
DE102009026810A1 (de) 2009-06-08 2010-12-09 Henkel Ag & Co. Kgaa Nanopartikuläres Mangandioxid
BRPI1012179B1 (pt) 2009-06-12 2019-05-07 Unilever N.V. Composição detergente e método doméstico de tratamento de tecidos
ES2436446T3 (es) 2009-06-15 2014-01-02 Unilever Nv Composición de detergente que comprende polímero colorante aniónico
WO2011005630A1 (fr) 2009-07-09 2011-01-13 The Procter & Gamble Company Procédé de lessive d'un tissu utilisant une composition détergente de lessive compactée
US20110009307A1 (en) 2009-07-09 2011-01-13 Alan Thomas Brooker Laundry Detergent Composition Comprising Low Level of Sulphate
EP2451925A1 (fr) 2009-07-09 2012-05-16 The Procter & Gamble Company Procédé de lessive d'un tissu utilisant une composition détergente de lessive compactée
CA2767110A1 (fr) 2009-07-09 2011-01-13 The Procter & Gamble Company Procede continu de fabrication d'une composition de detergent pour le linge
EP2451920A1 (fr) 2009-07-09 2012-05-16 The Procter & Gamble Company Procédé pour laver des textiles à l'aide d'une composition détergente de lavage sous forme de tablettes
US20110005001A1 (en) 2009-07-09 2011-01-13 Eric San Jose Robles Detergent Composition
US20110005002A1 (en) 2009-07-09 2011-01-13 Hiroshi Oh Method of Laundering Fabric
WO2011005844A1 (fr) 2009-07-09 2011-01-13 The Procter & Gamble Company Procédé de lessive d'un tissu utilisant une composition détergente de lessive compactée
WO2011005623A1 (fr) 2009-07-09 2011-01-13 The Procter & Gamble Company Composition détergente pour lessive comprenant de faibles taux d'agent de blanchiment
CN102471729A (zh) 2009-07-09 2012-05-23 宝洁公司 包含较低含量水溶性电解质的催化性衣物洗涤剂组合物
BR112012000492A2 (pt) 2009-07-09 2019-09-24 Procter & Gamble composição detergente moderadamente alcalina, com baixos teores de coadjuvantes que compreende ácido fitalimido peroxicaproico para tratamento de tecido sólido
WO2011016958A2 (fr) 2009-07-27 2011-02-10 The Procter & Gamble Company Composition détergente
ES2581916T5 (es) 2009-08-13 2022-11-07 Procter & Gamble Método para lavado de tejidos a baja temperatura
DE102009028891A1 (de) 2009-08-26 2011-03-03 Henkel Ag & Co. Kgaa Verbesserte Waschleistung durch Radikalfänger
WO2011036263A1 (fr) 2009-09-25 2011-03-31 Novozymes A/S Variants de subtilase
CN102648277B (zh) 2009-09-25 2015-05-20 诺维信公司 蛋白酶变体的用途
WO2011084417A1 (fr) 2009-12-21 2011-07-14 Danisco Us Inc. Compositions détergentes contenant une lipase issue de geobacillus stearothermophilus et leurs procédés d'utilisation
BR112012017056A2 (pt) 2009-12-21 2016-11-22 Danisco Us Inc "composições detergentes contendo lipase de bacillus subtilis e métodos para uso das mesmas"
CN102712879A (zh) 2009-12-21 2012-10-03 丹尼斯科美国公司 含有褐色喜热裂孢菌脂肪酶的洗涤剂组合物及其使用方法
US9896673B2 (en) 2010-02-10 2018-02-20 Novozymes A/S Compositions of high stability alpha amylase variants
WO2011130222A2 (fr) 2010-04-15 2011-10-20 Danisco Us Inc. Compositions et procédés comprenant des protéases variantes
AR081423A1 (es) 2010-05-28 2012-08-29 Danisco Us Inc Composiciones detergentes con contenido de lipasa de streptomyces griseus y metodos para utilizarlas
AU2012241055A1 (en) 2011-04-08 2013-08-15 Danisco Us, Inc. Compositions
CN103764823B (zh) 2011-05-05 2018-05-11 丹尼斯科美国公司 包含丝氨酸蛋白酶变体的组合物和方法
WO2013001087A2 (fr) 2011-06-30 2013-01-03 Novozymes A/S Procédé de criblage d'alpha-amylases
ES2834102T3 (es) 2011-06-30 2021-06-16 Novozymes As Variantes de alfa-amilasa
DE102012201522A1 (de) 2012-02-02 2013-08-08 Basf Se Lagerstabiles flüssiges Geschirrspülmittel enthaltend Protease und Amylase
CN104379737B (zh) 2012-06-08 2018-10-23 丹尼斯科美国公司 对淀粉聚合物具有增强的活性的变体α淀粉酶
CN107075493B (zh) 2014-12-04 2020-09-01 诺维信公司 枯草杆菌酶变体以及编码它们的多核苷酸
EP3887515A1 (fr) 2018-11-28 2021-10-06 Danisco US Inc. Variants de subtilisine à stabilité améliorée

Patent Citations (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1988008033A1 (fr) * 1987-04-10 1988-10-20 Amgen Inc. Analogues de subtilisine
WO1995010591A1 (fr) * 1993-10-14 1995-04-20 The Procter & Gamble Company Compositions de nettoyage contenant une protease
WO1998020116A1 (fr) * 1996-11-04 1998-05-14 Novo Nordisk A/S Variants de subtilase et compositions
US6555355B1 (en) * 1997-08-29 2003-04-29 Novozymes, A/S Protease variants and compositions
WO1999020726A1 (fr) * 1997-10-23 1999-04-29 The Procter & Gamble Company Compositions de blanchiment comprenant des variantes de protease multisubstituees
US6831053B1 (en) * 1998-10-23 2004-12-14 The Procter & Gamble Company Bleaching compositions comprising multiply-substituted protease variants
EP1403282A1 (fr) * 2002-09-26 2004-03-31 Cellzome Ag Complexes de protéines de la voie de signalisation du facteur de nécrose tumorale-alpha (TNF-alpha)
WO2004041979A2 (fr) * 2002-11-06 2004-05-21 Novozymes A/S Variantes de subtilase
US20090060933A1 (en) * 2004-06-14 2009-03-05 Estell David A Proteases producing an altered immunogenic response and methods of making and using the same
WO2009149200A2 (fr) * 2008-06-06 2009-12-10 Danisco Us Inc. Compositions et procédés comprenant des protéases microbiennes variantes
US20100192985A1 (en) * 2008-11-11 2010-08-05 Wolfgang Aehle Compositions and methods comprising serine protease variants
WO2010123754A1 (fr) * 2009-04-24 2010-10-28 Danisco Us Inc. Protéases avec des régions pro modifiées
US20130260438A1 (en) * 2010-05-06 2013-10-03 Danisco Us Inc. Compositions and methods comprising serine protease variants (as amended)

Non-Patent Citations (20)

* Cited by examiner, † Cited by third party
Title
BRYAN P N: "Protein engineering of subtilisin", BIOCHIMICA ET BIOPHYSICA ACTA. PROTEIN STRUCTURE AND MOLECULAR ENZYMOLOGY, ELSEVIER, AMSTERDAM; NL, vol. 1543, no. 2, 29 December 2000 (2000-12-29), pages 203 - 222, XP004279106, ISSN: 0167-4838, DOI: 10.1016/S0167-4838(00)00235-1 *
DATABASE EPO Proteins [online] 16 April 2004 (2004-04-16), "Sequence 42 from Patent EP1403282.", XP002745455, retrieved from EBI accession no. EPOP:CQ793824 Database accession no. CQ793824 *
DATABASE EPO Proteins [online] 23 January 2007 (2007-01-23), "Sequence 24 from Patent WO2006122655.", XP002745456, retrieved from EBI accession no. EPOP:CS463976 Database accession no. CS463976 *
DATABASE EPO Proteins [online] 24 November 2009 (2009-11-24), "Sequence 17 from Patent WO2009131740.", XP002745457, retrieved from EBI accession no. EPOP:HC069929 Database accession no. HC069929 *
DATABASE UniProt [online] 16 April 2014 (2014-04-16), "SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAF20430.1};", XP002745462, retrieved from EBI accession no. UNIPROT:W7ZAM3 Database accession no. W7ZAM3 *
DATABASE UniProt [online] 16 April 2014 (2014-04-16), "SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:GAF20430.1};", XP002753553, retrieved from EBI accession no. UNIPROT:W7ZAM3 Database accession no. W7ZAM3 *
DATABASE UniProt [online] 16 June 2009 (2009-06-16), "SubName: Full=Alkaline serine protease, subtilase {ECO:0000313|EMBL:EEL84605.1};", XP002745459, retrieved from EBI accession no. UNIPROT:C2ZHC0 Database accession no. C2ZHC0 *
DATABASE UniProt [online] 20 May 2008 (2008-05-20), "SubName: Full=Peptidase S8 and S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:ACB85709.1};", XP002753557, retrieved from EBI accession no. UNIPROT:B2A7K0 Database accession no. B2A7K0 *
DATABASE UniProt [online] 22 January 2014 (2014-01-22), "SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:AGX06526.1};", XP002745460, retrieved from EBI accession no. UNIPROT:U5LIK6 Database accession no. U5LIK6 *
DATABASE UniProt [online] 23 September 2008 (2008-09-23), "SubName: Full=Subtilisin Carlsberg {ECO:0000313|EMBL:EDW21217.1}; EC=3.4.21.62 {ECO:0000313|EMBL:EDW21217.1};", XP002753558, retrieved from EBI accession no. UNIPROT:B4ALD7 Database accession no. B4ALD7 *
DATABASE UniProt [online] 24 July 2013 (2013-07-24), "SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:EOQ58624.1};", XP002753554, retrieved from EBI accession no. UNIPROT:R8XNW4 Database accession no. R8XNW4 *
DATABASE UniProt [online] 28 November 2012 (2012-11-28), "SubName: Full=Intracellular serine protease {ECO:0000313|EMBL:EKF34975.1};", XP002745463, retrieved from EBI accession no. UNIPROT:K2N665 Database accession no. K2N665 *
DATABASE UniProt [online] 3 April 2013 (2013-04-03), "SubName: Full=Intracellular serine protease {ECO:0000313|EMBL:BAM51954.1};", XP002753556, retrieved from EBI accession no. UNIPROT:L8AIU5 Database accession no. L8AIU5 *
DATABASE UniProt [online] 3 October 2012 (2012-10-03), "SubName: Full=Subtilisin-like serine protease {ECO:0000313|EMBL:EJL27420.1}; Flags: Precursor;", XP002745464, retrieved from EBI accession no. UNIPROT:J2GC38 Database accession no. J2GC38 *
DATABASE UniProt [online] 3 October 2012 (2012-10-03), "SubName: Full=Subtilisin-like serine protease {ECO:0000313|EMBL:EJL39014.1}; Flags: Fragment;", XP002753555, retrieved from EBI accession no. UNIPROT:J3AWX1 Database accession no. J3AWX1 *
DATABASE UniProt [online] 5 April 2011 (2011-04-05), "SubName: Full=Peptidase S8/S53 subtilisin kexin sedolisin {ECO:0000313|EMBL:EFW90366.1};", XP002745461, retrieved from EBI accession no. UNIPROT:E7QYV0 Database accession no. E7QYV0 *
DATABASE USPTO Proteins [online] 14 December 2007 (2007-12-14), "Sequence 11 from patent US 7303907.", XP002745458, retrieved from EBI accession no. USPOP:ABY09838 Database accession no. ABY09838 *
PANTOLIANO M W ET AL: "LARGE INCREASES IN GENERAL STABILITY FOR SUBTILISIN BPN' THROUGH INCREMENTAL CHANGES IN THE FREE ENERGY OF UNFOLDING", BIOCHEMISTRY, AMERICAN CHEMICAL SOCIETY, US, vol. 28, no. 18, 5 September 1989 (1989-09-05), pages 7205 - 7213, XP000577069, ISSN: 0006-2960, DOI: 10.1021/BI00444A012 *
VON DER OSTEN C ET AL: "Protein engineering of subtilisins to improve stability in detergent formulations", JOURNAL OF BIOTECHNOLOGY, ELSEVIER SCIENCE PUBLISHERS, AMSTERDAM, NL, vol. 28, no. 1, 1 March 1993 (1993-03-01), pages 55 - 68, XP023944106, ISSN: 0168-1656, [retrieved on 19930301], DOI: 10.1016/0168-1656(93)90125-7 *
WONG C-H ET AL: "ENZYMES IN ORGANIC SYNTHESIS: USE OF SUBTILISIN AND A HIGHLY STABLE MUTANT DERIVED FROM MULTIPLE SITE-SPECIFIC MUTATIONS", JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, AMERICAN CHEMICAL SOCIETY, US, vol. 112, 1 January 1990 (1990-01-01), pages 945 - 953, XP000872434, ISSN: 0002-7863, DOI: 10.1021/JA00159A006 *

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