WO2020061499A8 - Plaque de puits fonctionnalisée, procédés de préparation et d'utilisation de celle-ci - Google Patents

Plaque de puits fonctionnalisée, procédés de préparation et d'utilisation de celle-ci Download PDF

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Publication number
WO2020061499A8
WO2020061499A8 PCT/US2019/052228 US2019052228W WO2020061499A8 WO 2020061499 A8 WO2020061499 A8 WO 2020061499A8 US 2019052228 W US2019052228 W US 2019052228W WO 2020061499 A8 WO2020061499 A8 WO 2020061499A8
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
methods
well plate
lymphocytes
functionalized well
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2019/052228
Other languages
English (en)
Other versions
WO2020061499A1 (fr
Inventor
Peter J. BEEMILLER
Alexander J. MASTROIANNI
Randall D. LOWE, Jr.
Yelena BRONEVETSKY
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bruker Cellular Analysis Inc
Original Assignee
Berkeley Lights Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to EP19861403.4A priority Critical patent/EP3853352A4/fr
Priority to JP2021515077A priority patent/JP2022502017A/ja
Priority to KR1020217011117A priority patent/KR20210063362A/ko
Priority to SG11202102489XA priority patent/SG11202102489XA/en
Priority to CA3112813A priority patent/CA3112813A1/fr
Priority to AU2019343994A priority patent/AU2019343994A1/en
Application filed by Berkeley Lights Inc filed Critical Berkeley Lights Inc
Priority to CN201980074146.1A priority patent/CN112996905A/zh
Publication of WO2020061499A1 publication Critical patent/WO2020061499A1/fr
Publication of WO2020061499A8 publication Critical patent/WO2020061499A8/fr
Priority to IL281640A priority patent/IL281640A/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/06—Plates; Walls; Drawers; Multilayer plates
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2806—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2818—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against CD28 or CD152
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K17/00—Carrier-bound or immobilised peptides; Preparation thereof
    • C07K17/02—Peptides being immobilised on, or in, an organic carrier
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/02—Form or structure of the vessel
    • C12M23/12—Well or multiwell plates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/20—Material Coatings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C12N5/0636—T lymphocytes
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5008—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics
    • G01N33/5044—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics involving specific cell types
    • G01N33/5047—Cells of the immune system
    • G01N33/505—Cells of the immune system involving T-cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Sustainable Development (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Medicinal Chemistry (AREA)
  • Hematology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Analytical Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)

Abstract

Dans les sciences biologiques et les domaines associés, il peut être utile de modifier des surfaces d'appareils, de dispositifs et de matériaux qui entrent en contact avec des biomatériaux tels que des biomolécules et des micro-objets biologiques. L'invention concerne des réactifs de modification de surface et de fonctionnalisation de surface, leur préparation, et des procédés pour modifier des surfaces de puits à l'intérieur d'une plaque de puits pour activer des lymphocytes, comprenant, mais sans s'y limiter des lymphocytes T, de manière contrôlable et reproductible.
PCT/US2019/052228 2018-09-21 2019-09-20 Plaque de puits fonctionnalisée, procédés de préparation et d'utilisation de celle-ci Ceased WO2020061499A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP2021515077A JP2022502017A (ja) 2018-09-21 2019-09-20 官能基化ウェルプレート、その作製及び使用方法
KR1020217011117A KR20210063362A (ko) 2018-09-21 2019-09-20 작용화된 웰 플레이트, 이의 제조 및 사용 방법
SG11202102489XA SG11202102489XA (en) 2018-09-21 2019-09-20 Functionalized well plate, methods of preparation and use thereof
CA3112813A CA3112813A1 (fr) 2018-09-21 2019-09-20 Plaque de puits fonctionnalisee, procedes de preparation et d'utilisation de celle-ci
AU2019343994A AU2019343994A1 (en) 2018-09-21 2019-09-20 Functionalized well plate, methods of preparation and use thereof
EP19861403.4A EP3853352A4 (fr) 2018-09-21 2019-09-20 Plaque de puits fonctionnalisée, procédés de préparation et d'utilisation de celle-ci
CN201980074146.1A CN112996905A (zh) 2018-09-21 2019-09-20 功能化的孔板、其制备和使用方法
IL281640A IL281640A (en) 2018-09-21 2021-03-18 Transformed multi-well plates, methods of their production and their uses

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201862734924P 2018-09-21 2018-09-21
US62/734,924 2018-09-21
US201962893712P 2019-08-29 2019-08-29
US62/893,712 2019-08-29

Publications (2)

Publication Number Publication Date
WO2020061499A1 WO2020061499A1 (fr) 2020-03-26
WO2020061499A8 true WO2020061499A8 (fr) 2020-05-07

Family

ID=69888950

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2019/052228 Ceased WO2020061499A1 (fr) 2018-09-21 2019-09-20 Plaque de puits fonctionnalisée, procédés de préparation et d'utilisation de celle-ci

Country Status (11)

Country Link
US (2) US11993766B2 (fr)
EP (1) EP3853352A4 (fr)
JP (1) JP2022502017A (fr)
KR (1) KR20210063362A (fr)
CN (1) CN112996905A (fr)
AU (1) AU2019343994A1 (fr)
CA (1) CA3112813A1 (fr)
IL (1) IL281640A (fr)
SG (1) SG11202102489XA (fr)
TW (1) TW202027761A (fr)
WO (1) WO2020061499A1 (fr)

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WO2025170547A1 (fr) * 2024-02-06 2025-08-14 Mahidol University Récepteur antigénique chimérique spécifique de cd19 comprenant un domaine co-stimulateur cd28/cd40

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KR20210063362A (ko) 2021-06-01
CA3112813A1 (fr) 2020-03-26
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US20200123491A1 (en) 2020-04-23
WO2020061499A1 (fr) 2020-03-26
US20250027019A1 (en) 2025-01-23
JP2022502017A (ja) 2022-01-11
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US11993766B2 (en) 2024-05-28

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