ZA200204594B - Vitamin D precursors, method and intermediates. - Google Patents

Vitamin D precursors, method and intermediates.

Info

Publication number: ZA200204594B
Authority: ZA; South Africa
Prior art keywords: intermediates; precursors; vitamin; relates; compounds
Prior art date: 1999-12-08

Application number

ZA200204594A

Other languages

English (en)

Inventor

Jean-Claude Pascal

Maurits Vandewalle

Philippe Maillos

Pierre De Clercq

Original Assignee

Theramex

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-12-08

Filing date

2002-06-07

Publication date

2003-10-29

2002-06-07 Application filed by Theramex filed Critical Theramex

2003-10-29 Publication of ZA200204594B publication Critical patent/ZA200204594B/xx

Links

229930003316 Vitamin D Natural products 0.000 title abstract 2
QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 title abstract 2
239000000543 intermediate Substances 0.000 title abstract 2
239000002243 precursor Substances 0.000 title abstract 2
235000019166 vitamin D Nutrition 0.000 title abstract 2
239000011710 vitamin D Substances 0.000 title abstract 2
150000003710 vitamin D derivatives Chemical class 0.000 title abstract 2
229940046008 vitamin d Drugs 0.000 title abstract 2
150000001875 compounds Chemical class 0.000 abstract 2
UYEMGAFJOZZIFP-UHFFFAOYSA-N 3,5-dihydroxybenzoic acid Chemical class OC(=O)C1=CC(O)=CC(O)=C1 UYEMGAFJOZZIFP-UHFFFAOYSA-N 0.000 abstract 1
230000002255 enzymatic effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C07F7/1872—Preparation; Treatments not provided for in C07F7/20
- C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
- C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
- C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
- C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
- C07C69/78—Benzoic acid esters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
- C07C2602/14—All rings being cycloaliphatic
- C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2602/00—Systems containing two condensed rings
- C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
- C07C2602/40—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing six carbon atoms

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Chemical Kinetics & Catalysis (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Catalysts (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Investigating Or Analysing Biological Materials (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Cephalosporin Compounds (AREA)

ZA200204594A 1999-12-08 2002-06-07 Vitamin D precursors, method and intermediates. ZA200204594B (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP99403065A EP1106618A1 (en)	1999-12-08	1999-12-08	Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof
US09/456,509 US6191292B1 (en)	1999-12-08	1999-12-08	Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof

Publications (1)

Publication Number	Publication Date
ZA200204594B true ZA200204594B (en)	2003-10-29

Family

ID=26153704

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200204594A ZA200204594B (en)	1999-12-08	2002-06-07	Vitamin D precursors, method and intermediates.

Country Status (23)

Country	Link
US (1)	US6191292B1 (cs)
EP (2)	EP1106618A1 (cs)
CN (1)	CN1210282C (cs)
AT (1)	ATE254623T1 (cs)
AU (1)	AU782089B2 (cs)
BR (1)	BRPI0016184B8 (cs)
CA (1)	CA2393617C (cs)
CZ (1)	CZ303421B6 (cs)
DE (1)	DE60006714T2 (cs)
DK (1)	DK1235832T3 (cs)
EE (1)	EE05326B1 (cs)
ES (1)	ES2210022T3 (cs)
HU (1)	HU229508B1 (cs)
IL (1)	IL150089A0 (cs)
MX (1)	MXPA01012904A (cs)
NO (1)	NO327848B1 (cs)
NZ (1)	NZ519391A (cs)
PL (1)	PL201691B1 (cs)
PT (1)	PT1235832E (cs)
RU (1)	RU2247710C2 (cs)
TW (1)	TWI290928B (cs)
WO (1)	WO2001042251A1 (cs)
ZA (1)	ZA200204594B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DK2360145T3 (da)	2010-01-26	2012-07-09	Hybrigenics Sa	Hidtil ukendt fremgangsmåde til isomerisering af kondenserede bicykliske strukturer og fremstilling af D-vitaminanaloger, der omfatter disse
CN104010525B (zh) *	2011-12-21	2017-08-25	默克专利股份有限公司	环己醇衍生物作为抗菌抗微生物活性物质的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
AU699200B2 (en) *	1993-07-09	1998-11-26	Roger Bouillon	Novel structural analogues of vitamin D

1999
- 1999-12-08 EP EP99403065A patent/EP1106618A1/en not_active Withdrawn
- 1999-12-08 US US09/456,509 patent/US6191292B1/en not_active Expired - Lifetime
2000
- 2000-10-30 TW TW089122845A patent/TWI290928B/zh not_active IP Right Cessation
- 2000-12-04 DE DE60006714T patent/DE60006714T2/de not_active Expired - Lifetime
- 2000-12-04 PT PT00983224T patent/PT1235832E/pt unknown
- 2000-12-04 IL IL15008900A patent/IL150089A0/xx active IP Right Grant
- 2000-12-04 HU HU0204521A patent/HU229508B1/hu unknown
- 2000-12-04 PL PL356389A patent/PL201691B1/pl unknown
- 2000-12-04 EP EP00983224A patent/EP1235832B1/en not_active Expired - Lifetime
- 2000-12-04 CA CA2393617A patent/CA2393617C/en not_active Expired - Lifetime
- 2000-12-04 CN CNB008184984A patent/CN1210282C/zh not_active Expired - Lifetime
- 2000-12-04 EE EEP200200294A patent/EE05326B1/xx unknown
- 2000-12-04 ES ES00983224T patent/ES2210022T3/es not_active Expired - Lifetime
- 2000-12-04 RU RU2002118103/04A patent/RU2247710C2/ru active
- 2000-12-04 AT AT00983224T patent/ATE254623T1/de active
- 2000-12-04 WO PCT/EP2000/012225 patent/WO2001042251A1/en not_active Ceased
- 2000-12-04 BR BRPI0016184A patent/BRPI0016184B8/pt not_active IP Right Cessation
- 2000-12-04 AU AU20051/01A patent/AU782089B2/en not_active Expired
- 2000-12-04 CZ CZ20021977A patent/CZ303421B6/cs not_active IP Right Cessation
- 2000-12-04 NZ NZ519391A patent/NZ519391A/en not_active IP Right Cessation
- 2000-12-04 MX MXPA01012904A patent/MXPA01012904A/es active IP Right Grant
- 2000-12-04 DK DK00983224T patent/DK1235832T3/da active
2002
- 2002-06-06 NO NO20022690A patent/NO327848B1/no not_active IP Right Cessation
- 2002-06-07 ZA ZA200204594A patent/ZA200204594B/xx unknown

Also Published As

Publication number	Publication date
CN1210282C (zh)	2005-07-13
CN1425019A (zh)	2003-06-18
EP1106618A1 (en)	2001-06-13
TWI290928B (en)	2007-12-11
WO2001042251A1 (en)	2001-06-14
CA2393617C (en)	2010-03-23
NO20022690D0 (no)	2002-06-06
DE60006714T2 (de)	2004-12-02
HUP0204521A2 (en)	2003-05-28
PL201691B1 (pl)	2009-04-30
BR0016184A (pt)	2002-08-20
DE60006714D1 (de)	2003-12-24
ATE254623T1 (de)	2003-12-15
CZ303421B6 (cs)	2012-09-05
NZ519391A (en)	2003-08-29
HU229508B1 (en)	2014-01-28
EP1235832A1 (en)	2002-09-04
BRPI0016184B8 (pt)	2021-05-25
RU2247710C2 (ru)	2005-03-10
US6191292B1 (en)	2001-02-20
CA2393617A1 (en)	2001-06-14
EP1235832B1 (en)	2003-11-19
AU782089B2 (en)	2005-06-30
HUP0204521A3 (en)	2005-03-29
EE05326B1 (et)	2010-08-16
ES2210022T3 (es)	2004-07-01
CZ20021977A3 (cs)	2002-10-16
PT1235832E (pt)	2004-04-30
BRPI0016184B1 (pt)	2015-07-14
PL356389A1 (en)	2004-06-28
EE200200294A (et)	2003-08-15
NO327848B1 (no)	2009-10-05
AU2005101A (en)	2001-06-18
NO20022690L (no)	2002-06-06
MXPA01012904A (es)	2002-11-07
DK1235832T3 (da)	2004-03-22
IL150089A0 (en)	2002-12-01

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