DK1235832T3 - Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser - Google Patents

Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser

Info

Publication number
DK1235832T3
DK1235832T3 DK00983224T DK00983224T DK1235832T3 DK 1235832 T3 DK1235832 T3 DK 1235832T3 DK 00983224 T DK00983224 T DK 00983224T DK 00983224 T DK00983224 T DK 00983224T DK 1235832 T3 DK1235832 T3 DK 1235832T3
Authority
DK
Denmark
Prior art keywords
intermediates
precursors
vitamin
preparation
processes
Prior art date
Application number
DK00983224T
Other languages
Danish (da)
English (en)
Inventor
Maurits Vandewalle
Clercq Pierre De
Philippe Maillos
Jean-Claude Pascal
Original Assignee
Theramex
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Theramex filed Critical Theramex
Application granted granted Critical
Publication of DK1235832T3 publication Critical patent/DK1235832T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C07F7/1872—Preparation; Treatments not provided for in C07F7/20
    • C07F7/1892—Preparation; Treatments not provided for in C07F7/20 by reactions not provided for in C07F7/1876 - C07F7/1888
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C07C29/38—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones
    • C07C29/40—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal by reaction with aldehydes or ketones with compounds containing carbon-to-metal bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/76—Esters of carboxylic acids having a carboxyl group bound to a carbon atom of a six-membered aromatic ring
    • C07C69/78—Benzoic acid esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02—Silicon compounds
    • C07F7/08—Compounds having one or more C—Si linkages
    • C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804—Compounds having Si-O-C linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14—The ring being saturated
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/18—All rings being cycloaliphatic the ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/36—Systems containing two condensed rings the rings having more than two atoms in common
    • C07C2602/40—Systems containing two condensed rings the rings having more than two atoms in common the bicyclo ring system containing six carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Catalysts (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Cephalosporin Compounds (AREA)
DK00983224T 1999-12-08 2000-12-04 Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser DK1235832T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99403065A EP1106618A1 (en) 1999-12-08 1999-12-08 Precursors of the A-ring of vitamin D, and method and intermediates for the preparation thereof
US09/456,509 US6191292B1 (en) 1999-12-08 1999-12-08 Precursors of the A-ring of vitamin D and method and intermediates for the preparation thereof
PCT/EP2000/012225 WO2001042251A1 (en) 1999-12-08 2000-12-04 Vitamin d precursors, method and intermediates

Publications (1)

Publication Number Publication Date
DK1235832T3 true DK1235832T3 (da) 2004-03-22

Family

ID=26153704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00983224T DK1235832T3 (da) 1999-12-08 2000-12-04 Precursorer for vitamin D, fremgangsmåde til fremstilling heraf og mellemforbindelser

Country Status (23)

Country Link
US (1) US6191292B1 (cs)
EP (2) EP1106618A1 (cs)
CN (1) CN1210282C (cs)
AT (1) ATE254623T1 (cs)
AU (1) AU782089B2 (cs)
BR (1) BRPI0016184B8 (cs)
CA (1) CA2393617C (cs)
CZ (1) CZ303421B6 (cs)
DE (1) DE60006714T2 (cs)
DK (1) DK1235832T3 (cs)
EE (1) EE05326B1 (cs)
ES (1) ES2210022T3 (cs)
HU (1) HU229508B1 (cs)
IL (1) IL150089A0 (cs)
MX (1) MXPA01012904A (cs)
NO (1) NO327848B1 (cs)
NZ (1) NZ519391A (cs)
PL (1) PL201691B1 (cs)
PT (1) PT1235832E (cs)
RU (1) RU2247710C2 (cs)
TW (1) TWI290928B (cs)
WO (1) WO2001042251A1 (cs)
ZA (1) ZA200204594B (cs)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK2360145T3 (da) 2010-01-26 2012-07-09 Hybrigenics Sa Hidtil ukendt fremgangsmåde til isomerisering af kondenserede bicykliske strukturer og fremstilling af D-vitaminanaloger, der omfatter disse
CN104010525B (zh) * 2011-12-21 2017-08-25 默克专利股份有限公司 环己醇衍生物作为抗菌抗微生物活性物质的用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU699200B2 (en) * 1993-07-09 1998-11-26 Roger Bouillon Novel structural analogues of vitamin D

Also Published As

Publication number Publication date
CN1210282C (zh) 2005-07-13
CN1425019A (zh) 2003-06-18
EP1106618A1 (en) 2001-06-13
TWI290928B (en) 2007-12-11
WO2001042251A1 (en) 2001-06-14
CA2393617C (en) 2010-03-23
NO20022690D0 (no) 2002-06-06
DE60006714T2 (de) 2004-12-02
HUP0204521A2 (en) 2003-05-28
PL201691B1 (pl) 2009-04-30
BR0016184A (pt) 2002-08-20
DE60006714D1 (de) 2003-12-24
ATE254623T1 (de) 2003-12-15
CZ303421B6 (cs) 2012-09-05
NZ519391A (en) 2003-08-29
HU229508B1 (en) 2014-01-28
EP1235832A1 (en) 2002-09-04
BRPI0016184B8 (pt) 2021-05-25
ZA200204594B (en) 2003-10-29
RU2247710C2 (ru) 2005-03-10
US6191292B1 (en) 2001-02-20
CA2393617A1 (en) 2001-06-14
EP1235832B1 (en) 2003-11-19
AU782089B2 (en) 2005-06-30
HUP0204521A3 (en) 2005-03-29
EE05326B1 (et) 2010-08-16
ES2210022T3 (es) 2004-07-01
CZ20021977A3 (cs) 2002-10-16
PT1235832E (pt) 2004-04-30
BRPI0016184B1 (pt) 2015-07-14
PL356389A1 (en) 2004-06-28
EE200200294A (et) 2003-08-15
NO327848B1 (no) 2009-10-05
AU2005101A (en) 2001-06-18
NO20022690L (no) 2002-06-06
MXPA01012904A (es) 2002-11-07
IL150089A0 (en) 2002-12-01

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