ZA200210247B - Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. - Google Patents

Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. Download PDF

Info

Publication number
ZA200210247B
ZA200210247B ZA200210247A ZA200210247A ZA200210247B ZA 200210247 B ZA200210247 B ZA 200210247B ZA 200210247 A ZA200210247 A ZA 200210247A ZA 200210247 A ZA200210247 A ZA 200210247A ZA 200210247 B ZA200210247 B ZA 200210247B
Authority
ZA
South Africa
Prior art keywords
formula
compound
protecting group
process according
salt
Prior art date
Application number
ZA200210247A
Other languages
English (en)
Inventor
Nigel Phillip Taylor
Phillip John Hogan
Edward John Bush
Claire Ingrid Pulling
Michael Senior William
Kevin William Leslie
Francis Joseph Montgomery
Kay Alison Boardman
Alan Charles Barker
Craig Steven Harris
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200210247B publication Critical patent/ZA200210247B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Cell Biology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ZA200210247A 2000-07-22 2002-12-18 Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. ZA200210247B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0017979.6A GB0017979D0 (en) 2000-07-22 2000-07-22 Chemical process

Publications (1)

Publication Number Publication Date
ZA200210247B true ZA200210247B (en) 2003-10-31

Family

ID=9896124

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200210247A ZA200210247B (en) 2000-07-22 2002-12-18 Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide.

Country Status (18)

Country Link
US (1) US20040101864A1 (cs)
EP (1) EP1320538A2 (cs)
JP (1) JP2004504405A (cs)
KR (1) KR20030033001A (cs)
CN (1) CN1617881A (cs)
AU (1) AU2001270863A1 (cs)
BR (1) BR0112652A (cs)
CA (1) CA2412787A1 (cs)
CZ (1) CZ2003165A3 (cs)
GB (1) GB0017979D0 (cs)
HU (1) HUP0400485A3 (cs)
IL (1) IL153364A0 (cs)
MX (1) MXPA03000607A (cs)
NO (1) NO20030317L (cs)
NZ (1) NZ523217A (cs)
PL (1) PL365426A1 (cs)
WO (1) WO2002008247A2 (cs)
ZA (1) ZA200210247B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130286D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
GB0130285D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
US7923577B2 (en) 2009-04-27 2011-04-12 International Flavors & Fragrances Inc. Menthylcarboxamides and their use as cooling agents
JP6084021B2 (ja) * 2012-12-04 2017-02-22 富士通テン株式会社 表示システム、表示装置、表示方法、及び、プログラム
CN111848433B (zh) * 2020-07-14 2023-04-28 安徽中草香料股份有限公司 4-氨基苯基乙酰胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1155925A (en) * 1967-02-16 1969-06-25 Miles Lab Synthesis Of Octapeptides
US4152322A (en) * 1978-04-28 1979-05-01 Merck & Co., Inc. Process for selective reduction of nitroarginyl peptides with titanium (iii)
GB9702377D0 (en) * 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
BR0112652A (pt) 2003-07-01
US20040101864A1 (en) 2004-05-27
WO2002008247A3 (en) 2002-10-17
JP2004504405A (ja) 2004-02-12
CN1617881A (zh) 2005-05-18
CZ2003165A3 (cs) 2003-04-16
NZ523217A (en) 2004-07-30
CA2412787A1 (en) 2002-01-31
MXPA03000607A (es) 2003-05-14
NO20030317L (no) 2003-03-14
HUP0400485A3 (en) 2005-02-28
GB0017979D0 (en) 2000-09-13
IL153364A0 (en) 2003-07-06
EP1320538A2 (en) 2003-06-25
KR20030033001A (ko) 2003-04-26
AU2001270863A1 (en) 2002-02-05
WO2002008247A2 (en) 2002-01-31
PL365426A1 (en) 2005-01-10
HUP0400485A2 (hu) 2004-06-28
NO20030317D0 (no) 2003-01-21

Similar Documents

Publication Publication Date Title
US8754225B2 (en) Process for preparing a biphenyl-2-ylcarbamic acid
EP1995254B1 (en) Method of producing peptides
CA2383184A1 (en) A process for the preparation of h-tyr-d-ala-phe(f)-phe-nh2
US6211333B1 (en) Method for producing peptides and their salts which have an agonist activity of luteinizing hormone releasing hormones secreted from the hypothalamus
NO166532B (no) Fremgangsmaate for fremstilling av peptidet h-arg-x-z-y-tyr-r.
US3645996A (en) Resins useful in peptide synthesis
EP0755374B1 (en) Process for peptide segment condensation
US20040101864A1 (en) Chemical process
JPS63258459A (ja) 結晶性キナプリルおよびその製法
EP0665229A1 (en) Process for the production of nucleic acid base derivatives
JP2002506880A (ja) テトラペプチドの製法
WO2012117410A1 (en) A process for the preparation of n-[2-[(acetylthio) methyl]-1-oxo-3-phenylpropyl] glycine phenyl methyl ester and intermediates thereof
JP2013528214A (ja) 結晶性エザチオスタット塩酸塩非溶媒和物ｄ型の調製
WO2003051909A2 (en) Process for the manufacture of pharmaceutically acceptable salts of a compound
AU725683B2 (en) Process for the preparation of NMDA antagonists
Gal et al. A new and simple method of resolution. Preparation of 3-fluoro-D-alanine-2-d
CN109053771B (zh) 一种托法替布的有关物质及其制备方法和应用
WO2007085933A2 (en) Process for the preparation of n-[1-(s)-ethoxycarbonyl-1-butyl]-(s)-alanine-dmt complex and its use in the preparation of perindopril
HK40114205A (en) Deprotection method and resin removal method in solid-phase reaction for peptide compound or amide compound, and method for producing peptide compound
US4600532A (en) Process and composition for amino-terminal, α-aspartyl and α-glutamyl dipeptides and dipeptide esters
CA2369267A1 (en) Method for producing amidines
CN111943894A (zh) 一种4,7-二氮杂螺[2.5]辛烷类化合物的合成方法
WO2003051918A1 (en) Solution-phase process for the manufacture of decapeptide
BG97839A (bg) Метод за получаване на клиндамицин палмитат хидрохлорид
JPH06107628A (ja) Ｎ−（アミノスクシニル）フェニルアラニンアルキルエステルの製造方法