ZA200210247B - Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. - Google Patents

Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. Download PDF

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Publication number
ZA200210247B
ZA200210247B ZA200210247A ZA200210247A ZA200210247B ZA 200210247 B ZA200210247 B ZA 200210247B ZA 200210247 A ZA200210247 A ZA 200210247A ZA 200210247 A ZA200210247 A ZA 200210247A ZA 200210247 B ZA200210247 B ZA 200210247B
Authority
ZA
South Africa
Prior art keywords
formula
compound
protecting group
process according
salt
Prior art date
Application number
ZA200210247A
Other languages
English (en)
Inventor
Nigel Phillip Taylor
Phillip John Hogan
Edward John Bush
Claire Ingrid Pulling
Michael Senior William
Kevin William Leslie
Francis Joseph Montgomery
Kay Alison Boardman
Alan Charles Barker
Craig Steven Harris
Original Assignee
Astrazeneca Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astrazeneca Ab filed Critical Astrazeneca Ab
Publication of ZA200210247B publication Critical patent/ZA200210247B/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/02—Linear peptides containing at least one abnormal peptide link
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70539—MHC-molecules, e.g. HLA-molecules

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Cell Biology (AREA)
  • Rehabilitation Therapy (AREA)
  • Rheumatology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pyrrole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
ZA200210247A 2000-07-22 2002-12-18 Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide. ZA200210247B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB0017979.6A GB0017979D0 (en) 2000-07-22 2000-07-22 Chemical process

Publications (1)

Publication Number Publication Date
ZA200210247B true ZA200210247B (en) 2003-10-31

Family

ID=9896124

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200210247A ZA200210247B (en) 2000-07-22 2002-12-18 Process for the preparation of 5-phenylpentanoyl-ala-argl-{2-[3-amino-2-oxopyrrolidin-1-yl]propionyl}-ala-arg-ala-4-aminophenyl acetamide.

Country Status (18)

Country Link
US (1) US20040101864A1 (cs)
EP (1) EP1320538A2 (cs)
JP (1) JP2004504405A (cs)
KR (1) KR20030033001A (cs)
CN (1) CN1617881A (cs)
AU (1) AU2001270863A1 (cs)
BR (1) BR0112652A (cs)
CA (1) CA2412787A1 (cs)
CZ (1) CZ2003165A3 (cs)
GB (1) GB0017979D0 (cs)
HU (1) HUP0400485A3 (cs)
IL (1) IL153364A0 (cs)
MX (1) MXPA03000607A (cs)
NO (1) NO20030317L (cs)
NZ (1) NZ523217A (cs)
PL (1) PL365426A1 (cs)
WO (1) WO2002008247A2 (cs)
ZA (1) ZA200210247B (cs)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0130285D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
GB0130286D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
US7923577B2 (en) 2009-04-27 2011-04-12 International Flavors & Fragrances Inc. Menthylcarboxamides and their use as cooling agents
JP6084021B2 (ja) * 2012-12-04 2017-02-22 富士通テン株式会社 表示システム、表示装置、表示方法、及び、プログラム
CN111848433B (zh) * 2020-07-14 2023-04-28 安徽中草香料股份有限公司 4-氨基苯基乙酰胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1155925A (en) * 1967-02-16 1969-06-25 Miles Lab Synthesis Of Octapeptides
US4152322A (en) * 1978-04-28 1979-05-01 Merck & Co., Inc. Process for selective reduction of nitroarginyl peptides with titanium (iii)
GB9702377D0 (en) * 1996-02-23 1997-03-26 Zeneca Ltd Peptide derivatives

Also Published As

Publication number Publication date
BR0112652A (pt) 2003-07-01
MXPA03000607A (es) 2003-05-14
WO2002008247A2 (en) 2002-01-31
AU2001270863A1 (en) 2002-02-05
EP1320538A2 (en) 2003-06-25
JP2004504405A (ja) 2004-02-12
IL153364A0 (en) 2003-07-06
CZ2003165A3 (cs) 2003-04-16
US20040101864A1 (en) 2004-05-27
GB0017979D0 (en) 2000-09-13
NO20030317L (no) 2003-03-14
PL365426A1 (en) 2005-01-10
CN1617881A (zh) 2005-05-18
CA2412787A1 (en) 2002-01-31
WO2002008247A3 (en) 2002-10-17
KR20030033001A (ko) 2003-04-26
HUP0400485A3 (en) 2005-02-28
HUP0400485A2 (hu) 2004-06-28
NZ523217A (en) 2004-07-30
NO20030317D0 (no) 2003-01-21

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