ZA200307865B - Composition improving age-related physiological deficits and increasing longevity. - Google Patents

Composition improving age-related physiological deficits and increasing longevity. Download PDF

Info

Publication number: ZA200307865B
Authority: ZA; South Africa
Prior art keywords: antioxidant; food composition; prevent; function; age
Prior art date: 2001-03-09

Application number

ZA200307865A

Other languages

English (en)

Inventor

Armand Malnoe

Sylvie Pridmore-Merten

Original Assignee

Nestle Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-03-09

Filing date

2003-10-08

Publication date

2005-01-10

2003-10-08 Application filed by Nestle Sa filed Critical Nestle Sa

2005-01-10 Publication of ZA200307865B publication Critical patent/ZA200307865B/en

Links

239000000203 mixture Substances 0.000 title claims description 56
230000006735 deficit Effects 0.000 title claims description 30
235000013305 food Nutrition 0.000 claims description 71
239000003963 antioxidant agent Substances 0.000 claims description 38
235000006708 antioxidants Nutrition 0.000 claims description 38
108090000623 proteins and genes Proteins 0.000 claims description 33
230000003078 antioxidant effect Effects 0.000 claims description 31
210000003470 mitochondria Anatomy 0.000 claims description 28
238000000034 method Methods 0.000 claims description 26
230000037149 energy metabolism Effects 0.000 claims description 25
241000124008 Mammalia Species 0.000 claims description 19
230000014509 gene expression Effects 0.000 claims description 19
235000020934 caloric restriction Nutrition 0.000 claims description 18
210000004027 cell Anatomy 0.000 claims description 18
150000001720 carbohydrates Chemical class 0.000 claims description 16
230000000694 effects Effects 0.000 claims description 16
230000032683 aging Effects 0.000 claims description 14
230000037396 body weight Effects 0.000 claims description 14
244000005700 microbiome Species 0.000 claims description 14
PHIQHXFUZVPYII-ZCFIWIBFSA-N (R)-carnitine Chemical group C[N+](C)(C)C[C@H](O)CC([O-])=O PHIQHXFUZVPYII-ZCFIWIBFSA-N 0.000 claims description 13
239000000284 extract Substances 0.000 claims description 12
RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims description 12
239000006041 probiotic Substances 0.000 claims description 12
230000000529 probiotic effect Effects 0.000 claims description 12
235000018291 probiotics Nutrition 0.000 claims description 12
235000013406 prebiotics Nutrition 0.000 claims description 11
CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 claims description 10
150000001875 compounds Chemical class 0.000 claims description 9
XOAAWQZATWQOTB-UHFFFAOYSA-N taurine Chemical compound NCCS(O)(=O)=O XOAAWQZATWQOTB-UHFFFAOYSA-N 0.000 claims description 8
ZGSPNIOCEDOHGS-UHFFFAOYSA-L disodium [3-[2,3-di(octadeca-9,12-dienoyloxy)propoxy-oxidophosphoryl]oxy-2-hydroxypropyl] 2,3-di(octadeca-9,12-dienoyloxy)propyl phosphate Chemical compound [Na+].[Na+].CCCCCC=CCC=CCCCCCCCC(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COP([O-])(=O)OCC(O)COP([O-])(=O)OCC(OC(=O)CCCCCCCC=CCC=CCCCCC)COC(=O)CCCCCCCC=CCC=CCCCCC ZGSPNIOCEDOHGS-UHFFFAOYSA-L 0.000 claims description 7
230000006870 function Effects 0.000 claims description 7
230000003278 mimic effect Effects 0.000 claims description 7
210000002027 skeletal muscle Anatomy 0.000 claims description 7
GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 6
CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 6
230000015572 biosynthetic process Effects 0.000 claims description 6
235000018417 cysteine Nutrition 0.000 claims description 6
XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims description 6
235000015872 dietary supplement Nutrition 0.000 claims description 6
235000020686 ginkgo biloba extract Nutrition 0.000 claims description 6
229960003180 glutathione Drugs 0.000 claims description 6
230000004054 inflammatory process Effects 0.000 claims description 6
108010024636 Glutathione Proteins 0.000 claims description 5
206010022489 Insulin Resistance Diseases 0.000 claims description 5
210000000988 bone and bone Anatomy 0.000 claims description 5
230000037180 bone health Effects 0.000 claims description 5
235000017471 coenzyme Q10 Nutrition 0.000 claims description 5
230000003920 cognitive function Effects 0.000 claims description 5
229960003624 creatine Drugs 0.000 claims description 5
239000006046 creatine Substances 0.000 claims description 5
235000014113 dietary fatty acids Nutrition 0.000 claims description 5
230000004438 eyesight Effects 0.000 claims description 5
239000000194 fatty acid Substances 0.000 claims description 5
229930195729 fatty acid Natural products 0.000 claims description 5
150000004665 fatty acids Chemical class 0.000 claims description 5
235000002532 grape seed extract Nutrition 0.000 claims description 5
230000036541 health Effects 0.000 claims description 5
230000036737 immune function Effects 0.000 claims description 5
230000003871 intestinal function Effects 0.000 claims description 5
230000037231 joint health Effects 0.000 claims description 5
230000004220 muscle function Effects 0.000 claims description 5
210000004165 myocardium Anatomy 0.000 claims description 5
230000001105 regulatory effect Effects 0.000 claims description 5
230000008786 sensory perception of smell Effects 0.000 claims description 5
230000013707 sensory perception of sound Effects 0.000 claims description 5
230000004218 vascular function Effects 0.000 claims description 5
244000269722 Thea sinensis Species 0.000 claims description 4
229930003427 Vitamin E Natural products 0.000 claims description 4
230000006851 antioxidant defense Effects 0.000 claims description 4
230000004064 dysfunction Effects 0.000 claims description 4
235000013599 spices Nutrition 0.000 claims description 4
229960003080 taurine Drugs 0.000 claims description 4
150000003573 thiols Chemical class 0.000 claims description 4
235000019154 vitamin C Nutrition 0.000 claims description 4
239000011718 vitamin C Substances 0.000 claims description 4
235000019165 vitamin E Nutrition 0.000 claims description 4
239000011709 vitamin E Substances 0.000 claims description 4
WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 claims description 3
RUDATBOHQWOJDD-UHFFFAOYSA-N (3beta,5beta,7alpha)-3,7-Dihydroxycholan-24-oic acid Natural products OC1CC2CC(O)CCC2(C)C2C1C1CCC(C(CCC(O)=O)C)C1(C)CC2 RUDATBOHQWOJDD-UHFFFAOYSA-N 0.000 claims description 3
ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims description 3
XUJNEKJLAYXESH-REOHCLBHSA-N L-Cysteine Chemical compound SC[C@H](N)C(O)=O XUJNEKJLAYXESH-REOHCLBHSA-N 0.000 claims description 3
FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims description 3
235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 3
235000003140 Panax quinquefolius Nutrition 0.000 claims description 3
MEFKEPWMEQBLKI-AIRLBKTGSA-N S-adenosyl-L-methioninate Chemical compound O[C@@H]1[C@H](O)[C@@H](C[S+](CC[C@H](N)C([O-])=O)C)O[C@H]1N1C2=NC=NC(N)=C2N=C1 MEFKEPWMEQBLKI-AIRLBKTGSA-N 0.000 claims description 3
102000019197 Superoxide Dismutase Human genes 0.000 claims description 3
108010012715 Superoxide dismutase Proteins 0.000 claims description 3
229930003268 Vitamin C Natural products 0.000 claims description 3
235000009754 Vitis X bourquina Nutrition 0.000 claims description 3
235000012333 Vitis X labruscana Nutrition 0.000 claims description 3
240000006365 Vitis vinifera Species 0.000 claims description 3
235000014787 Vitis vinifera Nutrition 0.000 claims description 3
229960001570 ademetionine Drugs 0.000 claims description 3
235000021466 carotenoid Nutrition 0.000 claims description 3
150000001747 carotenoids Chemical class 0.000 claims description 3
150000001765 catechin Chemical class 0.000 claims description 3
ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 claims description 3
235000005487 catechin Nutrition 0.000 claims description 3
229920002770 condensed tannin Polymers 0.000 claims description 3
229960002433 cysteine Drugs 0.000 claims description 3
229960003067 cystine Drugs 0.000 claims description 3
229930004069 diterpene Natural products 0.000 claims description 3
125000000567 diterpene group Chemical group 0.000 claims description 3
229930003935 flavonoid Natural products 0.000 claims description 3
235000017173 flavonoids Nutrition 0.000 claims description 3
150000002215 flavonoids Chemical class 0.000 claims description 3
WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 3
235000008434 ginseng Nutrition 0.000 claims description 3
238000001727 in vivo Methods 0.000 claims description 3
CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims description 3
150000002515 isoflavone derivatives Chemical class 0.000 claims description 3
235000008696 isoflavones Nutrition 0.000 claims description 3
AGBQKNBQESQNJD-UHFFFAOYSA-M lipoate Chemical compound [O-]C(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-M 0.000 claims description 3
235000019136 lipoic acid Nutrition 0.000 claims description 3
229930182817 methionine Natural products 0.000 claims description 3
229960004452 methionine Drugs 0.000 claims description 3
235000020660 omega-3 fatty acid Nutrition 0.000 claims description 3
229940012843 omega-3 fatty acid Drugs 0.000 claims description 3
239000006014 omega-3 oil Substances 0.000 claims description 3
239000003075 phytoestrogen Substances 0.000 claims description 3
150000008442 polyphenolic compounds Chemical class 0.000 claims description 3
235000013824 polyphenols Nutrition 0.000 claims description 3
235000013616 tea Nutrition 0.000 claims description 3
229960002663 thioctic acid Drugs 0.000 claims description 3
150000003669 ubiquinones Chemical class 0.000 claims description 3
RUDATBOHQWOJDD-UZVSRGJWSA-N ursodeoxycholic acid Chemical compound C([C@H]1C[C@@H]2O)[C@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@@H](CCC(O)=O)C)[C@@]2(C)CC1 RUDATBOHQWOJDD-UZVSRGJWSA-N 0.000 claims description 3
229960001661 ursodiol Drugs 0.000 claims description 3
229940096998 ursolic acid Drugs 0.000 claims description 3
PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 claims description 3
229940046009 vitamin E Drugs 0.000 claims description 3
102100035882 Catalase Human genes 0.000 claims description 2
108010053835 Catalase Proteins 0.000 claims description 2
108010070675 Glutathione transferase Proteins 0.000 claims description 2
241000411851 herbal medicine Species 0.000 claims description 2
241000208340 Araliaceae Species 0.000 claims 2
LEVWYRKDKASIDU-QWWZWVQMSA-N D-cystine Chemical compound OC(=O)[C@H](N)CSSC[C@@H](N)C(O)=O LEVWYRKDKASIDU-QWWZWVQMSA-N 0.000 claims 2
DFPAKSUCGFBDDF-UHFFFAOYSA-N Nicotinamide Chemical compound NC(=O)C1=CC=CN=C1 DFPAKSUCGFBDDF-UHFFFAOYSA-N 0.000 claims 2
102100029100 Hematopoietic prostaglandin D synthase Human genes 0.000 claims 1
229960003966 nicotinamide Drugs 0.000 claims 1
235000005152 nicotinamide Nutrition 0.000 claims 1
239000011570 nicotinamide Substances 0.000 claims 1
238000002560 therapeutic procedure Methods 0.000 claims 1
239000003925 fat Substances 0.000 description 25
235000019197 fats Nutrition 0.000 description 25
235000005911 diet Nutrition 0.000 description 22
230000037213 diet Effects 0.000 description 22
235000018102 proteins Nutrition 0.000 description 21
102000004169 proteins and genes Human genes 0.000 description 21
235000014633 carbohydrates Nutrition 0.000 description 17
235000016709 nutrition Nutrition 0.000 description 17
241001465754 Metazoa Species 0.000 description 14
235000010469 Glycine max Nutrition 0.000 description 8
241000699670 Mus sp. Species 0.000 description 8
235000021307 Triticum Nutrition 0.000 description 7
241000209140 Triticum Species 0.000 description 7
235000021196 dietary intervention Nutrition 0.000 description 7
239000003921 oil Substances 0.000 description 7
235000019198 oils Nutrition 0.000 description 7
239000000047 product Substances 0.000 description 7
239000011782 vitamin Substances 0.000 description 7
OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 6
229920002472 Starch Polymers 0.000 description 6
235000019577 caloric intake Nutrition 0.000 description 6
229960004203 carnitine Drugs 0.000 description 6
230000007423 decrease Effects 0.000 description 6
150000002632 lipids Chemical class 0.000 description 6
230000008569 process Effects 0.000 description 6
235000019698 starch Nutrition 0.000 description 6
235000013343 vitamin Nutrition 0.000 description 6
229930003231 vitamin Natural products 0.000 description 6
229940088594 vitamin Drugs 0.000 description 6
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 6
241000282472 Canis lupus familiaris Species 0.000 description 5
244000298479 Cichorium intybus Species 0.000 description 5
235000007542 Cichorium intybus Nutrition 0.000 description 5
229930006000 Sucrose Natural products 0.000 description 5
CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 5
108010046377 Whey Proteins Proteins 0.000 description 5
240000008042 Zea mays Species 0.000 description 5
235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 5
235000002017 Zea mays subsp mays Nutrition 0.000 description 5
235000005822 corn Nutrition 0.000 description 5
235000013312 flour Nutrition 0.000 description 5
229910052500 inorganic mineral Inorganic materials 0.000 description 5
229960004232 linoleic acid Drugs 0.000 description 5
238000004519 manufacturing process Methods 0.000 description 5
239000011159 matrix material Substances 0.000 description 5
239000011707 mineral Substances 0.000 description 5
235000010755 mineral Nutrition 0.000 description 5
230000004792 oxidative damage Effects 0.000 description 5
239000000843 powder Substances 0.000 description 5
150000003839 salts Chemical class 0.000 description 5
235000012424 soybean oil Nutrition 0.000 description 5
239000003549 soybean oil Substances 0.000 description 5
239000008107 starch Substances 0.000 description 5
230000000638 stimulation Effects 0.000 description 5
239000005720 sucrose Substances 0.000 description 5
108010068370 Glutens Proteins 0.000 description 4
241000186660 Lactobacillus Species 0.000 description 4
LCTONWCANYUPML-UHFFFAOYSA-M Pyruvate Chemical compound CC(=O)C([O-])=O LCTONWCANYUPML-UHFFFAOYSA-M 0.000 description 4
235000019485 Safflower oil Nutrition 0.000 description 4
108010073771 Soybean Proteins Proteins 0.000 description 4
235000019486 Sunflower oil Nutrition 0.000 description 4
239000005862 Whey Substances 0.000 description 4
102000007544 Whey Proteins Human genes 0.000 description 4
MBMBGCFOFBJSGT-KUBAVDMBSA-N all-cis-docosa-4,7,10,13,16,19-hexaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCC(O)=O MBMBGCFOFBJSGT-KUBAVDMBSA-N 0.000 description 4
239000000975 dye Substances 0.000 description 4
229940098330 gamma linoleic acid Drugs 0.000 description 4
VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 description 4
VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 description 4
235000021312 gluten Nutrition 0.000 description 4
229940039696 lactobacillus Drugs 0.000 description 4
150000004668 long chain fatty acids Chemical class 0.000 description 4
239000000463 material Substances 0.000 description 4
235000012054 meals Nutrition 0.000 description 4
235000013372 meat Nutrition 0.000 description 4
239000012528 membrane Substances 0.000 description 4
235000013336 milk Nutrition 0.000 description 4
239000008267 milk Substances 0.000 description 4
210000004080 milk Anatomy 0.000 description 4
238000007254 oxidation reaction Methods 0.000 description 4
244000144977 poultry Species 0.000 description 4
235000013594 poultry meat Nutrition 0.000 description 4
239000003642 reactive oxygen metabolite Substances 0.000 description 4
235000005713 safflower oil Nutrition 0.000 description 4
239000003813 safflower oil Substances 0.000 description 4
229940001941 soy protein Drugs 0.000 description 4
239000002600 sunflower oil Substances 0.000 description 4
235000007319 Avena orientalis Nutrition 0.000 description 3
235000007558 Avena sp Nutrition 0.000 description 3
241000222120 Candida <Saccharomycetales> Species 0.000 description 3
102000015781 Dietary Proteins Human genes 0.000 description 3
108010010256 Dietary Proteins Proteins 0.000 description 3
241000196324 Embryophyta Species 0.000 description 3
RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical class OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 3
239000009429 Ginkgo biloba extract Substances 0.000 description 3
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
229920002907 Guar gum Polymers 0.000 description 3
108010011756 Milk Proteins Proteins 0.000 description 3
102000014171 Milk Proteins Human genes 0.000 description 3
108020005196 Mitochondrial DNA Proteins 0.000 description 3
240000007594 Oryza sativa Species 0.000 description 3
235000007164 Oryza sativa Nutrition 0.000 description 3
235000019484 Rapeseed oil Nutrition 0.000 description 3
230000004075 alteration Effects 0.000 description 3
WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 3
239000001913 cellulose Substances 0.000 description 3
229920002678 cellulose Polymers 0.000 description 3
235000013325 dietary fiber Nutrition 0.000 description 3
235000021245 dietary protein Nutrition 0.000 description 3
229940068052 ginkgo biloba extract Drugs 0.000 description 3
239000008103 glucose Substances 0.000 description 3
235000010417 guar gum Nutrition 0.000 description 3
239000000665 guar gum Substances 0.000 description 3
229960002154 guar gum Drugs 0.000 description 3
235000021239 milk protein Nutrition 0.000 description 3
235000021281 monounsaturated fatty acids Nutrition 0.000 description 3
-1 nicotinamide, carbohydrate Chemical class 0.000 description 3
239000004006 olive oil Substances 0.000 description 3
235000008390 olive oil Nutrition 0.000 description 3
230000010627 oxidative phosphorylation Effects 0.000 description 3
238000002360 preparation method Methods 0.000 description 3
230000006318 protein oxidation Effects 0.000 description 3
235000009566 rice Nutrition 0.000 description 3
235000015112 vegetable and seed oil Nutrition 0.000 description 3
102000004482 ATP Translocases Mitochondrial ADP Human genes 0.000 description 2
108010017236 ATP Translocases Mitochondrial ADP Proteins 0.000 description 2
ZKHQWZAMYRWXGA-KQYNXXCUSA-N Adenosine triphosphate Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](COP(O)(=O)OP(O)(=O)OP(O)(O)=O)[C@@H](O)[C@H]1O ZKHQWZAMYRWXGA-KQYNXXCUSA-N 0.000 description 2
241000209763 Avena sativa Species 0.000 description 2
235000014698 Brassica juncea var multisecta Nutrition 0.000 description 2
235000006008 Brassica napus var napus Nutrition 0.000 description 2
235000006618 Brassica rapa subsp oleifera Nutrition 0.000 description 2
244000188595 Brassica sinapistrum Species 0.000 description 2
235000004977 Brassica sinapistrum Nutrition 0.000 description 2
QRYRORQUOLYVBU-VBKZILBWSA-N Carnosic acid Natural products CC([C@@H]1CC2)(C)CCC[C@]1(C(O)=O)C1=C2C=C(C(C)C)C(O)=C1O QRYRORQUOLYVBU-VBKZILBWSA-N 0.000 description 2
108010087806 Carnosine Proteins 0.000 description 2
102000011632 Caseins Human genes 0.000 description 2
108010076119 Caseins Proteins 0.000 description 2
ACTIUHUUMQJHFO-UHFFFAOYSA-N Coenzym Q10 Natural products COC1=C(OC)C(=O)C(CC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UHFFFAOYSA-N 0.000 description 2
108010082495 Dietary Plant Proteins Proteins 0.000 description 2
102000002322 Egg Proteins Human genes 0.000 description 2
108010000912 Egg Proteins Proteins 0.000 description 2
241000194032 Enterococcus faecalis Species 0.000 description 2
108010086800 Glucose-6-Phosphatase Proteins 0.000 description 2
102000003638 Glucose-6-Phosphatase Human genes 0.000 description 2
241000282412 Homo Species 0.000 description 2
240000005979 Hordeum vulgare Species 0.000 description 2
235000007340 Hordeum vulgare Nutrition 0.000 description 2
244000199866 Lactobacillus casei Species 0.000 description 2
235000013958 Lactobacillus casei Nutrition 0.000 description 2
229920002774 Maltodextrin Polymers 0.000 description 2
CQOVPNPJLQNMDC-UHFFFAOYSA-N N-beta-alanyl-L-histidine Natural products NCCC(=O)NC(C(O)=O)CC1=CN=CN1 CQOVPNPJLQNMDC-UHFFFAOYSA-N 0.000 description 2
229910019142 PO4 Inorganic materials 0.000 description 2
241000191998 Pediococcus acidilactici Species 0.000 description 2
241000235070 Saccharomyces Species 0.000 description 2
244000062793 Sorghum vulgare Species 0.000 description 2
102000004357 Transferases Human genes 0.000 description 2
108090000992 Transferases Proteins 0.000 description 2
239000002253 acid Substances 0.000 description 2
150000007513 acids Chemical class 0.000 description 2
JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 description 2
235000021120 animal protein Nutrition 0.000 description 2
YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 description 2
230000008901 benefit Effects 0.000 description 2
230000008436 biogenesis Effects 0.000 description 2
235000021324 borage oil Nutrition 0.000 description 2
229940044199 carnosine Drugs 0.000 description 2
CQOVPNPJLQNMDC-ZETCQYMHSA-N carnosine Chemical compound [NH3+]CCC(=O)N[C@H](C([O-])=O)CC1=CNC=N1 CQOVPNPJLQNMDC-ZETCQYMHSA-N 0.000 description 2
239000005018 casein Substances 0.000 description 2
BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 description 2
235000021240 caseins Nutrition 0.000 description 2
ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 2
235000009508 confectionery Nutrition 0.000 description 2
235000020940 control diet Nutrition 0.000 description 2
238000010411 cooking Methods 0.000 description 2
JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 description 2
239000000839 emulsion Substances 0.000 description 2
235000008524 evening primrose extract Nutrition 0.000 description 2
239000010475 evening primrose oil Substances 0.000 description 2
229940089020 evening primrose oil Drugs 0.000 description 2
238000001125 extrusion Methods 0.000 description 2
229940013317 fish oils Drugs 0.000 description 2
230000004110 gluconeogenesis Effects 0.000 description 2
230000034659 glycolysis Effects 0.000 description 2
229940087603 grape seed extract Drugs 0.000 description 2
230000001771 impaired effect Effects 0.000 description 2
239000004615 ingredient Substances 0.000 description 2
239000000787 lecithin Substances 0.000 description 2
235000010445 lecithin Nutrition 0.000 description 2
235000020778 linoleic acid Nutrition 0.000 description 2
OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 2
210000004072 lung Anatomy 0.000 description 2
238000012423 maintenance Methods 0.000 description 2
230000004066 metabolic change Effects 0.000 description 2
230000004065 mitochondrial dysfunction Effects 0.000 description 2
210000003205 muscle Anatomy 0.000 description 2
235000021590 normal diet Nutrition 0.000 description 2
230000003647 oxidation Effects 0.000 description 2
NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 2
239000010452 phosphate Substances 0.000 description 2
235000020777 polyunsaturated fatty acids Nutrition 0.000 description 2
235000011962 puddings Nutrition 0.000 description 2
235000002639 sodium chloride Nutrition 0.000 description 2
235000000346 sugar Nutrition 0.000 description 2
239000013589 supplement Substances 0.000 description 2
238000003786 synthesis reaction Methods 0.000 description 2
235000020357 syrup Nutrition 0.000 description 2
239000006188 syrup Substances 0.000 description 2
239000005028 tinplate Substances 0.000 description 2
210000001519 tissue Anatomy 0.000 description 2
235000019871 vegetable fat Nutrition 0.000 description 2
239000001717 vitis vinifera seed extract Substances 0.000 description 2
WMBWREPUVVBILR-WIYYLYMNSA-N (-)-Epigallocatechin-3-o-gallate Chemical compound O([C@@H]1CC2=C(O)C=C(C=C2O[C@@H]1C=1C=C(O)C(O)=C(O)C=1)O)C(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-WIYYLYMNSA-N 0.000 description 1
DNISEZBAYYIQFB-PHDIDXHHSA-N (2r,3r)-2,3-diacetyloxybutanedioic acid Chemical class CC(=O)O[C@@H](C(O)=O)[C@H](C(O)=O)OC(C)=O DNISEZBAYYIQFB-PHDIDXHHSA-N 0.000 description 1
OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 description 1
GJJVAFUKOBZPCB-ZGRPYONQSA-N (r)-3,4-dihydro-2-methyl-2-(4,8,12-trimethyl-3,7,11-tridecatrienyl)-2h-1-benzopyran-6-ol Chemical class OC1=CC=C2OC(CC/C=C(C)/CC/C=C(C)/CCC=C(C)C)(C)CCC2=C1 GJJVAFUKOBZPCB-ZGRPYONQSA-N 0.000 description 1
IIZPXYDJLKNOIY-JXPKJXOSSA-N 1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphocholine Chemical compound CCCCCCCCCCCCCCCC(=O)OC[C@H](COP([O-])(=O)OCC[N+](C)(C)C)OC(=O)CCC\C=C/C\C=C/C\C=C/C\C=C/CCCCC IIZPXYDJLKNOIY-JXPKJXOSSA-N 0.000 description 1
WIGIZIANZCJQQY-UHFFFAOYSA-N 4-ethyl-3-methyl-N-[2-[4-[[[(4-methylcyclohexyl)amino]-oxomethyl]sulfamoyl]phenyl]ethyl]-5-oxo-2H-pyrrole-1-carboxamide Chemical compound O=C1C(CC)=C(C)CN1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCC(C)CC2)C=C1 WIGIZIANZCJQQY-UHFFFAOYSA-N 0.000 description 1
102100031126 6-phosphogluconolactonase Human genes 0.000 description 1
108010029731 6-phosphogluconolactonase Proteins 0.000 description 1
244000215068 Acacia senegal Species 0.000 description 1
241000251468 Actinopterygii Species 0.000 description 1
102100022089 Acyl-[acyl-carrier-protein] hydrolase Human genes 0.000 description 1
241000193798 Aerococcus Species 0.000 description 1
244000291564 Allium cepa Species 0.000 description 1
235000002732 Allium cepa var. cepa Nutrition 0.000 description 1
GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
102100038910 Alpha-enolase Human genes 0.000 description 1
235000019737 Animal fat Nutrition 0.000 description 1
244000003416 Asparagus officinalis Species 0.000 description 1
235000005340 Asparagus officinalis Nutrition 0.000 description 1
241000228212 Aspergillus Species 0.000 description 1
108010077173 BB Form Creatine Kinase Proteins 0.000 description 1
241000193830 Bacillus <bacterium> Species 0.000 description 1
241000193749 Bacillus coagulans Species 0.000 description 1
241000194108 Bacillus licheniformis Species 0.000 description 1
244000063299 Bacillus subtilis Species 0.000 description 1
235000014469 Bacillus subtilis Nutrition 0.000 description 1
241000894006 Bacteria Species 0.000 description 1
241000606125 Bacteroides Species 0.000 description 1
108091005658 Basic proteases Proteins 0.000 description 1
241000186000 Bifidobacterium Species 0.000 description 1
241000186016 Bifidobacterium bifidum Species 0.000 description 1
241001608472 Bifidobacterium longum Species 0.000 description 1
241000186015 Bifidobacterium longum subsp. infantis Species 0.000 description 1
101150071146 COX2 gene Proteins 0.000 description 1
101100114534 Caenorhabditis elegans ctc-2 gene Proteins 0.000 description 1
DNJVYWXIDISQRD-UHFFFAOYSA-N Cafestol Natural products C1CC2(CC3(CO)O)CC3CCC2C2(C)C1C(C=CO1)=C1CC2 DNJVYWXIDISQRD-UHFFFAOYSA-N 0.000 description 1
108010078791 Carrier Proteins Proteins 0.000 description 1
244000020518 Carthamus tinctorius Species 0.000 description 1
235000003255 Carthamus tinctorius Nutrition 0.000 description 1
102000003908 Cathepsin D Human genes 0.000 description 1
108090000258 Cathepsin D Proteins 0.000 description 1
102000004175 Cathepsin H Human genes 0.000 description 1
108090000619 Cathepsin H Proteins 0.000 description 1
101710163595 Chaperone protein DnaK Proteins 0.000 description 1
241000193403 Clostridium Species 0.000 description 1
102000004420 Creatine Kinase Human genes 0.000 description 1
108010042126 Creatine kinase Proteins 0.000 description 1
102100022785 Creatine kinase B-type Human genes 0.000 description 1
102000001493 Cyclophilins Human genes 0.000 description 1
108010068682 Cyclophilins Proteins 0.000 description 1
244000019459 Cynara cardunculus Species 0.000 description 1
235000019106 Cynara scolymus Nutrition 0.000 description 1
108050008072 Cytochrome c oxidase subunit IV Proteins 0.000 description 1
102000000634 Cytochrome c oxidase subunit IV Human genes 0.000 description 1
108020004414 DNA Proteins 0.000 description 1
239000004278 EU approved seasoning Substances 0.000 description 1
241000194033 Enterococcus Species 0.000 description 1
241000194031 Enterococcus faecium Species 0.000 description 1
108010039731 Fatty Acid Synthases Proteins 0.000 description 1
108010087894 Fatty acid desaturases Proteins 0.000 description 1
235000019733 Fish meal Nutrition 0.000 description 1
229930091371 Fructose Natural products 0.000 description 1
239000005715 Fructose Substances 0.000 description 1
OPGOLNDOMSBSCW-CLNHMMGSSA-N Fursultiamine hydrochloride Chemical compound Cl.C1CCOC1CSSC(\CCO)=C(/C)N(C=O)CC1=CN=C(C)N=C1N OPGOLNDOMSBSCW-CLNHMMGSSA-N 0.000 description 1
241000605909 Fusobacterium Species 0.000 description 1
WMBWREPUVVBILR-UHFFFAOYSA-N GCG Natural products C=1C(O)=C(O)C(O)=CC=1C1OC2=CC(O)=CC(O)=C2CC1OC(=O)C1=CC(O)=C(O)C(O)=C1 WMBWREPUVVBILR-UHFFFAOYSA-N 0.000 description 1
241000287828 Gallus gallus Species 0.000 description 1
235000011201 Ginkgo Nutrition 0.000 description 1
235000008100 Ginkgo biloba Nutrition 0.000 description 1
244000194101 Ginkgo biloba Species 0.000 description 1
108010018962 Glucosephosphate Dehydrogenase Proteins 0.000 description 1
102000005720 Glutathione transferase Human genes 0.000 description 1
239000009140 Grape Seed Proanthocyanidin Substances 0.000 description 1
229920000084 Gum arabic Polymers 0.000 description 1
101710178376 Heat shock 70 kDa protein Proteins 0.000 description 1
101710152018 Heat shock cognate 70 kDa protein Proteins 0.000 description 1
244000020551 Helianthus annuus Species 0.000 description 1
235000003222 Helianthus annuus Nutrition 0.000 description 1
101000939438 Homo sapiens Mitochondrial brown fat uncoupling protein 1 Proteins 0.000 description 1
206010061218 Inflammation Diseases 0.000 description 1
229920001202 Inulin Polymers 0.000 description 1
206010023230 Joint stiffness Diseases 0.000 description 1
241000191953 Kocuria varians Species 0.000 description 1
LEVWYRKDKASIDU-IMJSIDKUSA-N L-cystine Chemical compound [O-]C(=O)[C@@H]([NH3+])CSSC[C@H]([NH3+])C([O-])=O LEVWYRKDKASIDU-IMJSIDKUSA-N 0.000 description 1
240000001046 Lactobacillus acidophilus Species 0.000 description 1
235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
241000186715 Lactobacillus alimentarius Species 0.000 description 1
241001134659 Lactobacillus curvatus Species 0.000 description 1
241000186606 Lactobacillus gasseri Species 0.000 description 1
240000002605 Lactobacillus helveticus Species 0.000 description 1
235000013967 Lactobacillus helveticus Nutrition 0.000 description 1
241001468157 Lactobacillus johnsonii Species 0.000 description 1
241000186604 Lactobacillus reuteri Species 0.000 description 1
241000218588 Lactobacillus rhamnosus Species 0.000 description 1
241000186612 Lactobacillus sakei Species 0.000 description 1
241000194036 Lactococcus Species 0.000 description 1
GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
241000192132 Leuconostoc Species 0.000 description 1
102000015930 Lon proteases Human genes 0.000 description 1
UPYKUZBSLRQECL-UKMVMLAPSA-N Lycopene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1C(=C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=C)CCCC2(C)C UPYKUZBSLRQECL-UKMVMLAPSA-N 0.000 description 1
JEVVKJMRZMXFBT-XWDZUXABSA-N Lycophyll Natural products OC/C(=C/CC/C(=C\C=C\C(=C/C=C/C(=C\C=C\C=C(/C=C/C=C(\C=C\C=C(/CC/C=C(/CO)\C)\C)/C)\C)/C)\C)/C)/C JEVVKJMRZMXFBT-XWDZUXABSA-N 0.000 description 1
102100033468 Lysozyme C Human genes 0.000 description 1
108050000633 Lysozyme C Proteins 0.000 description 1
108010059343 MM Form Creatine Kinase Proteins 0.000 description 1
239000005913 Maltodextrin Substances 0.000 description 1
108010070551 Meat Proteins Proteins 0.000 description 1
235000019735 Meat-and-bone meal Nutrition 0.000 description 1
241001468189 Melissococcus Species 0.000 description 1
241000192041 Micrococcus Species 0.000 description 1
102000000562 Monocarboxylic Acid Transporters Human genes 0.000 description 1
108010041817 Monocarboxylic Acid Transporters Proteins 0.000 description 1
241000235395 Mucor Species 0.000 description 1
241001529936 Murinae Species 0.000 description 1
BAWFJGJZGIEFAR-NNYOXOHSSA-O NAD(+) Chemical compound NC(=O)C1=CC=C[N+]([C@H]2[C@@H]([C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]3[C@H]([C@@H](O)[C@@H](O3)N3C4=NC=NC(N)=C4N=C3)O)O2)O)=C1 BAWFJGJZGIEFAR-NNYOXOHSSA-O 0.000 description 1
206010028980 Neoplasm Diseases 0.000 description 1
208000012902 Nervous system disease Diseases 0.000 description 1
208000025966 Neurological disease Diseases 0.000 description 1
241000202223 Oenococcus Species 0.000 description 1
108091034117 Oligonucleotide Proteins 0.000 description 1
101150000187 PTGS2 gene Proteins 0.000 description 1
235000019482 Palm oil Nutrition 0.000 description 1
240000004371 Panax ginseng Species 0.000 description 1
108010084695 Pea Proteins Proteins 0.000 description 1
235000019483 Peanut oil Nutrition 0.000 description 1
241000192001 Pediococcus Species 0.000 description 1
241000191996 Pediococcus pentosaceus Species 0.000 description 1
241000228143 Penicillium Species 0.000 description 1
108091005804 Peptidases Proteins 0.000 description 1
102000035195 Peptidases Human genes 0.000 description 1
108010092528 Phosphate Transport Proteins Proteins 0.000 description 1
102000016462 Phosphate Transport Proteins Human genes 0.000 description 1
102000011755 Phosphoglycerate Kinase Human genes 0.000 description 1
102000045595 Phosphoprotein Phosphatases Human genes 0.000 description 1
108010022181 Phosphopyruvate Hydratase Proteins 0.000 description 1
241000235648 Pichia Species 0.000 description 1
235000010582 Pisum sativum Nutrition 0.000 description 1
244000134540 Polymnia sonchifolia Species 0.000 description 1
235000003406 Polymnia sonchifolia Nutrition 0.000 description 1
241000186429 Propionibacterium Species 0.000 description 1
239000004365 Protease Substances 0.000 description 1
108010023294 Protease La Proteins 0.000 description 1
102000004245 Proteasome Endopeptidase Complex Human genes 0.000 description 1
108090000708 Proteasome Endopeptidase Complex Proteins 0.000 description 1
108010009736 Protein Hydrolysates Proteins 0.000 description 1
102000013009 Pyruvate Kinase Human genes 0.000 description 1
108020005115 Pyruvate Kinase Proteins 0.000 description 1
238000002123 RNA extraction Methods 0.000 description 1
241000235527 Rhizopus Species 0.000 description 1
102000002278 Ribosomal Proteins Human genes 0.000 description 1
108010000605 Ribosomal Proteins Proteins 0.000 description 1
235000019774 Rice Bran oil Nutrition 0.000 description 1
241000283984 Rodentia Species 0.000 description 1
244000178231 Rosmarinus officinalis Species 0.000 description 1
240000004808 Saccharomyces cerevisiae Species 0.000 description 1
102100023153 Sodium- and chloride-dependent creatine transporter 1 Human genes 0.000 description 1
235000011684 Sorghum saccharatum Nutrition 0.000 description 1
241000191940 Staphylococcus Species 0.000 description 1
241000191965 Staphylococcus carnosus Species 0.000 description 1
241000191973 Staphylococcus xylosus Species 0.000 description 1
102000016553 Stearoyl-CoA Desaturase Human genes 0.000 description 1
241000194017 Streptococcus Species 0.000 description 1
244000057717 Streptococcus lactis Species 0.000 description 1
235000014897 Streptococcus lactis Nutrition 0.000 description 1
241000194020 Streptococcus thermophilus Species 0.000 description 1
241000500332 Tetragenococcus halophilus Species 0.000 description 1
101001099217 Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) Triosephosphate isomerase Proteins 0.000 description 1
101710097834 Thiol protease Proteins 0.000 description 1
235000019498 Walnut oil Nutrition 0.000 description 1
241000202221 Weissella Species 0.000 description 1
ZNOZWUKQPJXOIG-XSBHQQIPSA-L [(2r,3s,4r,5r,6s)-6-[[(1r,3s,4r,5r,8s)-3,4-dihydroxy-2,6-dioxabicyclo[3.2.1]octan-8-yl]oxy]-4-[[(1r,3r,4r,5r,8s)-8-[(2s,3r,4r,5r,6r)-3,4-dihydroxy-6-(hydroxymethyl)-5-sulfonatooxyoxan-2-yl]oxy-4-hydroxy-2,6-dioxabicyclo[3.2.1]octan-3-yl]oxy]-5-hydroxy-2-( Chemical compound O[C@@H]1[C@@H](O)[C@@H](OS([O-])(=O)=O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H]2OC[C@H]1O[C@H](O[C@H]1[C@H]([C@@H](CO)O[C@@H](O[C@@H]3[C@@H]4OC[C@H]3O[C@H](O)[C@@H]4O)[C@@H]1O)OS([O-])(=O)=O)[C@@H]2O ZNOZWUKQPJXOIG-XSBHQQIPSA-L 0.000 description 1
239000000205 acacia gum Substances 0.000 description 1
235000010489 acacia gum Nutrition 0.000 description 1
239000012190 activator Substances 0.000 description 1
239000013543 active substance Substances 0.000 description 1
125000002252 acyl group Chemical group 0.000 description 1
230000006978 adaptation Effects 0.000 description 1
JKQXZKUSFCKOGQ-LOFNIBRQSA-N all-trans-Zeaxanthin Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2=C(C)CC(O)CC2(C)C JKQXZKUSFCKOGQ-LOFNIBRQSA-N 0.000 description 1
235000001014 amino acid Nutrition 0.000 description 1
150000001413 amino acids Chemical class 0.000 description 1
238000013459 approach Methods 0.000 description 1
235000021342 arachidonic acid Nutrition 0.000 description 1
229940114079 arachidonic acid Drugs 0.000 description 1
235000016520 artichoke thistle Nutrition 0.000 description 1
229940054340 bacillus coagulans Drugs 0.000 description 1
239000011324 bead Substances 0.000 description 1
235000021336 beef liver Nutrition 0.000 description 1
230000009286 beneficial effect Effects 0.000 description 1
235000013361 beverage Nutrition 0.000 description 1
229940002008 bifidobacterium bifidum Drugs 0.000 description 1
229940004120 bifidobacterium infantis Drugs 0.000 description 1
229940009291 bifidobacterium longum Drugs 0.000 description 1
210000004556 brain Anatomy 0.000 description 1
235000015496 breakfast cereal Nutrition 0.000 description 1
DNJVYWXIDISQRD-JTSSGKSMSA-N cafestol Chemical compound C([C@H]1C[C@]2(C[C@@]1(CO)O)CC1)C[C@H]2[C@@]2(C)[C@H]1C(C=CO1)=C1CC2 DNJVYWXIDISQRD-JTSSGKSMSA-N 0.000 description 1
201000011510 cancer Diseases 0.000 description 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 description 1
230000000747 cardiac effect Effects 0.000 description 1
235000005473 carotenes Nutrition 0.000 description 1
150000001746 carotenes Chemical class 0.000 description 1
239000000969 carrier Substances 0.000 description 1
230000030833 cell death Effects 0.000 description 1
239000000919 ceramic Substances 0.000 description 1
235000013339 cereals Nutrition 0.000 description 1
230000008859 change Effects 0.000 description 1
235000013351 cheese Nutrition 0.000 description 1
239000003795 chemical substances by application Substances 0.000 description 1
230000001684 chronic effect Effects 0.000 description 1
239000003240 coconut oil Substances 0.000 description 1
235000019864 coconut oil Nutrition 0.000 description 1
230000001149 cognitive effect Effects 0.000 description 1
235000008504 concentrate Nutrition 0.000 description 1
239000012141 concentrate Substances 0.000 description 1
238000012790 confirmation Methods 0.000 description 1
235000005687 corn oil Nutrition 0.000 description 1
239000002285 corn oil Substances 0.000 description 1
108010007169 creatine transporter Proteins 0.000 description 1
235000015140 cultured milk Nutrition 0.000 description 1
230000001186 cumulative effect Effects 0.000 description 1
235000013365 dairy product Nutrition 0.000 description 1
238000013461 design Methods 0.000 description 1
238000001784 detoxification Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
230000018109 developmental process Effects 0.000 description 1
230000009274 differential gene expression Effects 0.000 description 1
210000002249 digestive system Anatomy 0.000 description 1
229940079593 drug Drugs 0.000 description 1
239000003814 drug Substances 0.000 description 1
238000001035 drying Methods 0.000 description 1
239000003995 emulsifying agent Substances 0.000 description 1
230000001804 emulsifying effect Effects 0.000 description 1
229940032049 enterococcus faecalis Drugs 0.000 description 1
229940030275 epigallocatechin gallate Drugs 0.000 description 1
235000004626 essential fatty acids Nutrition 0.000 description 1
230000004136 fatty acid synthesis Effects 0.000 description 1
238000011049 filling Methods 0.000 description 1
239000004467 fishmeal Substances 0.000 description 1
239000000796 flavoring agent Substances 0.000 description 1
235000013355 food flavoring agent Nutrition 0.000 description 1
235000019138 food restriction Nutrition 0.000 description 1
235000011194 food seasoning agent Nutrition 0.000 description 1
239000003349 gelling agent Substances 0.000 description 1
238000011223 gene expression profiling Methods 0.000 description 1
108010015485 glucose 1,6-diphosphate phosphatase Proteins 0.000 description 1
ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 description 1
150000004676 glycans Chemical class 0.000 description 1
125000002966 glycerophosphoglycerophosphoglycerol group Chemical group 0.000 description 1
235000009569 green tea Nutrition 0.000 description 1
238000010438 heat treatment Methods 0.000 description 1
230000013632 homeostatic process Effects 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
230000028709 inflammatory response Effects 0.000 description 1
210000000936 intestine Anatomy 0.000 description 1
230000003834 intracellular effect Effects 0.000 description 1
JYJIGFIDKWBXDU-MNNPPOADSA-N inulin Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)OC[C@]1(OC[C@]2(OC[C@]3(OC[C@]4(OC[C@]5(OC[C@]6(OC[C@]7(OC[C@]8(OC[C@]9(OC[C@]%10(OC[C@]%11(OC[C@]%12(OC[C@]%13(OC[C@]%14(OC[C@]%15(OC[C@]%16(OC[C@]%17(OC[C@]%18(OC[C@]%19(OC[C@]%20(OC[C@]%21(OC[C@]%22(OC[C@]%23(OC[C@]%24(OC[C@]%25(OC[C@]%26(OC[C@]%27(OC[C@]%28(OC[C@]%29(OC[C@]%30(OC[C@]%31(OC[C@]%32(OC[C@]%33(OC[C@]%34(OC[C@]%35(OC[C@]%36(O[C@@H]%37[C@@H]([C@@H](O)[C@H](O)[C@@H](CO)O%37)O)[C@H]([C@H](O)[C@@H](CO)O%36)O)[C@H]([C@H](O)[C@@H](CO)O%35)O)[C@H]([C@H](O)[C@@H](CO)O%34)O)[C@H]([C@H](O)[C@@H](CO)O%33)O)[C@H]([C@H](O)[C@@H](CO)O%32)O)[C@H]([C@H](O)[C@@H](CO)O%31)O)[C@H]([C@H](O)[C@@H](CO)O%30)O)[C@H]([C@H](O)[C@@H](CO)O%29)O)[C@H]([C@H](O)[C@@H](CO)O%28)O)[C@H]([C@H](O)[C@@H](CO)O%27)O)[C@H]([C@H](O)[C@@H](CO)O%26)O)[C@H]([C@H](O)[C@@H](CO)O%25)O)[C@H]([C@H](O)[C@@H](CO)O%24)O)[C@H]([C@H](O)[C@@H](CO)O%23)O)[C@H]([C@H](O)[C@@H](CO)O%22)O)[C@H]([C@H](O)[C@@H](CO)O%21)O)[C@H]([C@H](O)[C@@H](CO)O%20)O)[C@H]([C@H](O)[C@@H](CO)O%19)O)[C@H]([C@H](O)[C@@H](CO)O%18)O)[C@H]([C@H](O)[C@@H](CO)O%17)O)[C@H]([C@H](O)[C@@H](CO)O%16)O)[C@H]([C@H](O)[C@@H](CO)O%15)O)[C@H]([C@H](O)[C@@H](CO)O%14)O)[C@H]([C@H](O)[C@@H](CO)O%13)O)[C@H]([C@H](O)[C@@H](CO)O%12)O)[C@H]([C@H](O)[C@@H](CO)O%11)O)[C@H]([C@H](O)[C@@H](CO)O%10)O)[C@H]([C@H](O)[C@@H](CO)O9)O)[C@H]([C@H](O)[C@@H](CO)O8)O)[C@H]([C@H](O)[C@@H](CO)O7)O)[C@H]([C@H](O)[C@@H](CO)O6)O)[C@H]([C@H](O)[C@@H](CO)O5)O)[C@H]([C@H](O)[C@@H](CO)O4)O)[C@H]([C@H](O)[C@@H](CO)O3)O)[C@H]([C@H](O)[C@@H](CO)O2)O)[C@@H](O)[C@H](O)[C@@H](CO)O1 JYJIGFIDKWBXDU-MNNPPOADSA-N 0.000 description 1
229940029339 inulin Drugs 0.000 description 1
229940039695 lactobacillus acidophilus Drugs 0.000 description 1
229940017800 lactobacillus casei Drugs 0.000 description 1
229940054346 lactobacillus helveticus Drugs 0.000 description 1
229940001882 lactobacillus reuteri Drugs 0.000 description 1
239000008101 lactose Substances 0.000 description 1
229940067606 lecithin Drugs 0.000 description 1
239000000944 linseed oil Substances 0.000 description 1
235000021388 linseed oil Nutrition 0.000 description 1
235000014666 liquid concentrate Nutrition 0.000 description 1
210000004185 liver Anatomy 0.000 description 1
235000020978 long-chain polyunsaturated fatty acids Nutrition 0.000 description 1
230000007774 longterm Effects 0.000 description 1
235000012680 lutein Nutrition 0.000 description 1
229960005375 lutein Drugs 0.000 description 1
239000001656 lutein Substances 0.000 description 1
KBPHJBAIARWVSC-RGZFRNHPSA-N lutein Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\[C@H]1C(C)=C[C@H](O)CC1(C)C KBPHJBAIARWVSC-RGZFRNHPSA-N 0.000 description 1
ORAKUVXRZWMARG-WZLJTJAWSA-N lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C ORAKUVXRZWMARG-WZLJTJAWSA-N 0.000 description 1
235000012661 lycopene Nutrition 0.000 description 1
229960004999 lycopene Drugs 0.000 description 1
OAIJSZIZWZSQBC-GYZMGTAESA-N lycopene Chemical compound CC(C)=CCC\C(C)=C\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C=C(/C)CCC=C(C)C OAIJSZIZWZSQBC-GYZMGTAESA-N 0.000 description 1
239000001751 lycopene Substances 0.000 description 1
229940035034 maltodextrin Drugs 0.000 description 1
235000013622 meat product Nutrition 0.000 description 1
230000001404 mediated effect Effects 0.000 description 1
230000004060 metabolic process Effects 0.000 description 1
239000002207 metabolite Substances 0.000 description 1
238000002493 microarray Methods 0.000 description 1
230000000813 microbial effect Effects 0.000 description 1
235000019713 millet Nutrition 0.000 description 1
230000006677 mitochondrial metabolism Effects 0.000 description 1
230000004048 modification Effects 0.000 description 1
238000012986 modification Methods 0.000 description 1
230000004660 morphological change Effects 0.000 description 1
238000010172 mouse model Methods 0.000 description 1
230000003387 muscular Effects 0.000 description 1
208000015122 neurodegenerative disease Diseases 0.000 description 1
230000007935 neutral effect Effects 0.000 description 1
229930027945 nicotinamide-adenine dinucleotide Natural products 0.000 description 1
BOPGDPNILDQYTO-NNYOXOHSSA-N nicotinamide-adenine dinucleotide Chemical compound C1=CCC(C(=O)N)=CN1[C@H]1[C@H](O)[C@H](O)[C@@H](COP(O)(=O)OP(O)(=O)OC[C@@H]2[C@H]([C@@H](O)[C@@H](O2)N2C3=NC=NC(N)=C3N=C2)O)O1 BOPGDPNILDQYTO-NNYOXOHSSA-N 0.000 description 1
235000015097 nutrients Nutrition 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
235000006180 nutrition needs Nutrition 0.000 description 1
ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid group Chemical group C(CCCCCCC\C=C/CCCCCCCC)(=O)O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
229920001542 oligosaccharide Polymers 0.000 description 1
230000001590 oxidative effect Effects 0.000 description 1
235000019629 palatability Nutrition 0.000 description 1
239000002540 palm oil Substances 0.000 description 1
125000001312 palmitoyl group Chemical group O=C([*])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])[H] 0.000 description 1
235000019702 pea protein Nutrition 0.000 description 1
239000000312 peanut oil Substances 0.000 description 1
235000010987 pectin Nutrition 0.000 description 1
239000001814 pectin Substances 0.000 description 1
229920001277 pectin Polymers 0.000 description 1
239000008188 pellet Substances 0.000 description 1
150000003904 phospholipids Chemical class 0.000 description 1
229920001282 polysaccharide Polymers 0.000 description 1
239000005017 polysaccharide Substances 0.000 description 1
239000002243 precursor Substances 0.000 description 1
238000012545 processing Methods 0.000 description 1
239000003531 protein hydrolysate Substances 0.000 description 1
230000004844 protein turnover Effects 0.000 description 1
150000003254 radicals Chemical class 0.000 description 1
235000021580 ready-to-drink beverage Nutrition 0.000 description 1
230000003362 replicative effect Effects 0.000 description 1
230000000241 respiratory effect Effects 0.000 description 1
230000029058 respiratory gaseous exchange Effects 0.000 description 1
230000003938 response to stress Effects 0.000 description 1
210000003583 retinal pigment epithelium Anatomy 0.000 description 1
210000004708 ribosome subunit Anatomy 0.000 description 1
239000008165 rice bran oil Substances 0.000 description 1
235000015067 sauces Nutrition 0.000 description 1
235000021309 simple sugar Nutrition 0.000 description 1
239000007787 solid Substances 0.000 description 1
230000000392 somatic effect Effects 0.000 description 1
235000014347 soups Nutrition 0.000 description 1
239000007921 spray Substances 0.000 description 1
239000003381 stabilizer Substances 0.000 description 1
JIWBIWFOSCKQMA-UHFFFAOYSA-N stearidonic acid Natural products CCC=CCC=CCC=CCC=CCCCCC(O)=O JIWBIWFOSCKQMA-UHFFFAOYSA-N 0.000 description 1
230000035882 stress Effects 0.000 description 1
238000006467 substitution reaction Methods 0.000 description 1
239000000758 substrate Substances 0.000 description 1
230000004083 survival effect Effects 0.000 description 1
230000008961 swelling Effects 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
239000003760 tallow Substances 0.000 description 1
108090000721 thyroid hormone receptors Proteins 0.000 description 1
102000004217 thyroid hormone receptors Human genes 0.000 description 1
229930003799 tocopherol Natural products 0.000 description 1
239000011732 tocopherol Substances 0.000 description 1
125000002640 tocopherol group Chemical class 0.000 description 1
235000019149 tocopherols Nutrition 0.000 description 1
229930003802 tocotrienol Natural products 0.000 description 1
239000011731 tocotrienol Substances 0.000 description 1
229940068778 tocotrienols Drugs 0.000 description 1
235000019148 tocotrienols Nutrition 0.000 description 1
ZCIHMQAPACOQHT-ZGMPDRQDSA-N trans-isorenieratene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/c1c(C)ccc(C)c1C)C=CC=C(/C)C=Cc2c(C)ccc(C)c2C ZCIHMQAPACOQHT-ZGMPDRQDSA-N 0.000 description 1
KBPHJBAIARWVSC-XQIHNALSSA-N trans-lutein Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C(=CC(O)CC2(C)C)C KBPHJBAIARWVSC-XQIHNALSSA-N 0.000 description 1
230000004102 tricarboxylic acid cycle Effects 0.000 description 1
239000008158 vegetable oil Substances 0.000 description 1
239000008170 walnut oil Substances 0.000 description 1
230000004584 weight gain Effects 0.000 description 1
235000019786 weight gain Nutrition 0.000 description 1
235000021119 whey protein Nutrition 0.000 description 1
FJHBOVDFOQMZRV-XQIHNALSSA-N xanthophyll Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CC(O)CC1(C)C)C=CC=C(/C)C=CC2C=C(C)C(O)CC2(C)C FJHBOVDFOQMZRV-XQIHNALSSA-N 0.000 description 1
235000013618 yogurt Nutrition 0.000 description 1
JKQXZKUSFCKOGQ-QAYBQHTQSA-N zeaxanthin Chemical compound C([C@H](O)CC=1C)C(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)C[C@@H](O)CC1(C)C JKQXZKUSFCKOGQ-QAYBQHTQSA-N 0.000 description 1
GZIFEOYASATJEH-VHFRWLAGSA-N δ-tocopherol Chemical compound OC1=CC(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1 GZIFEOYASATJEH-VHFRWLAGSA-N 0.000 description 1

Classifications

- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/40—Feeding-stuffs specially adapted for particular animals for carnivorous animals, e.g. cats or dogs
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Polymers & Plastics (AREA)
Food Science & Technology (AREA)
Nutrition Science (AREA)
Mycology (AREA)
Diabetes (AREA)
Animal Husbandry (AREA)
Birds (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Immunology (AREA)
Rheumatology (AREA)
Zoology (AREA)
Physical Education & Sports Medicine (AREA)
Urology & Nephrology (AREA)
Emergency Medicine (AREA)
Dermatology (AREA)
Cardiology (AREA)
Hematology (AREA)
Ophthalmology & Optometry (AREA)
Pain & Pain Management (AREA)
Endocrinology (AREA)
Obesity (AREA)
Orthopedic Medicine & Surgery (AREA)
Heart & Thoracic Surgery (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)

ZA200307865A 2001-03-09 2003-10-08 Composition improving age-related physiological deficits and increasing longevity. ZA200307865B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
EP01200871		2001-03-09

Publications (1)

Publication Number	Publication Date
ZA200307865B true ZA200307865B (en)	2005-01-10

Family

ID=8179979

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA200307865A ZA200307865B (en)	2001-03-09	2003-10-08	Composition improving age-related physiological deficits and increasing longevity.

Country Status (17)

Country	Link
US (2)	US20040047896A1 (de)
EP (1)	EP1372412A2 (de)
JP (1)	JP2004519241A (de)
KR (1)	KR20030088453A (de)
CN (1)	CN1638650A (de)
AR (1)	AR032974A1 (de)
AU (1)	AU2008201296A1 (de)
BR (1)	BR0207948A (de)
CA (1)	CA2439078C (de)
EA (1)	EA006429B1 (de)
IL (2)	IL157367A0 (de)
MX (1)	MXPA03007802A (de)
NO (1)	NO20033941D0 (de)
PE (1)	PE20020987A1 (de)
PL (1)	PL363426A1 (de)
WO (1)	WO2002071874A2 (de)
ZA (1)	ZA200307865B (de)

Families Citing this family (132)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US8563522B2 (en) *	1997-07-08	2013-10-22	The Iams Company	Method of maintaining and/or attenuating a decline in quality of life
US20020076470A1 (en)	2000-10-31	2002-06-20	Colgate-Palmolive Company	Composition and method
US8669282B2 (en)	2000-10-31	2014-03-11	Hill's Pet Nutrition, Inc.	Companion animal compositions including lipoic acid and methods of use thereof
EP1243273A1 (de) †	2001-03-22	2002-09-25	Societe Des Produits Nestle S.A.	Zubereitung enthaltend einen praebiotischen Stoff für die Behandlung von Entzündungen und abnormale Aktivierung von nicht-spezifischen immunologischen Parametern
US7666459B2 (en) *	2001-09-12	2010-02-23	The Procter & Gamble Company	Pet food compositions
CO5400144A1 (es)	2002-03-11	2004-05-31	Novartis Ag	Compuestos organicos
DE60238663D1 (de) *	2002-04-05	2011-02-03	Nestle Sa	Zusammensetzungen und Verfahren zur Verbesserung von Lipidassimilation in Haustieren
CA2498199C (en) *	2002-09-09	2012-01-17	Nestec S.A.	Orally administrable composition for improving hair and coat quality
FI20022175A0 (fi) *	2002-12-10	2002-12-10	Labmax Oy	Elintarvikeöljyvalmiste ja sen käyttö
US20040191775A1 (en) *	2003-03-12	2004-09-30	Spindler Stephen R.	Methods of analyzing genes affected by caloric restriction or caloric restriction mimetics
US7332178B2 (en) *	2003-04-25	2008-02-19	Abbott Laboratories	Stable nutritional powder containing ascorbyl palmitate
US8192733B2 (en) *	2003-08-29	2012-06-05	Cobb & Associates	Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US7759105B2 (en) *	2003-08-29	2010-07-20	Cobb & Company, Llp	Probiotic composition useful for dietary augmentation and/or combating disease states and adverse physiological conditions
US7749509B2 (en) *	2003-08-29	2010-07-06	Cobb And Company, Llp	Treatment of autism using probiotic composition
US7731976B2 (en) *	2003-08-29	2010-06-08	Cobb And Company, Llp	Treatment of irritable bowel syndrome using probiotic composition
US20050090551A1 (en) *	2003-10-27	2005-04-28	Board Of Trustees Of Southern Illinois University	Therapeutic use of methionine for the treatment or prevention of mucositis
CA2546968A1 (en) *	2003-11-21	2005-06-16	Nestec S.A.	Food composition comprising glucosamine
US20050158294A1 (en)	2003-12-19	2005-07-21	The Procter & Gamble Company	Canine probiotic Bifidobacteria pseudolongum
US8877178B2 (en)	2003-12-19	2014-11-04	The Iams Company	Methods of use of probiotic bifidobacteria for companion animals
ES2809302T3 (es)	2004-01-22	2021-03-03	Univ Miami	Formulaciones de coenzima Q10 para tratar tumores sólidos mediante administración intravenosa
JP2007519678A (ja) *	2004-01-28	2007-07-19	ネステクソシエテアノニム	皮膚状態を改良しそして皮膚病を予防するための栄養組成物
US20090252834A1 (en) *	2004-05-10	2009-10-08	Michael Griffin Hayek	Compositions comprising glucose anti-metabolites
JP2007289001A (ja) *	2004-05-10	2007-11-08	Toyo Shinyaku:Kk	ポリフェノールを含有する食品
US20050266051A1 (en) *	2004-05-27	2005-12-01	The Procter & Gamble Company	Pet food compositions and methods
AU2012211482B2 (en) *	2004-05-27	2014-08-21	Mars, Incorporated	Pet food compositions and methods
DE102004026706A1 (de) *	2004-05-28	2005-12-15	Merck Patent Gmbh	Orale Darreichungsform enthaltend probiotische Bakterien
JP2006014730A (ja) *	2004-05-31	2006-01-19	Toyo Shinyaku:Kk	食品
JPWO2005123058A1 (ja) *	2004-06-15	2008-04-10	大阪府	老化防止剤
ES2458308T5 (es) *	2004-09-21	2020-08-18	Société des Produits Nestlé SA	Control de peso mejorado en animales de compañía de avanzada edad
EP1645276A1 (de) *	2004-10-08	2006-04-12	Wageningen Centre for Food Sciences	Behandlung von neurodegenerativen Erkrankungen
CN102784396B (zh) *	2004-11-09	2015-07-29	希尔氏宠物营养品公司	抗氧化剂用于基因调节的用途
WO2006058278A2 (en) *	2004-11-24	2006-06-01	Hill's Pet Nutrition, Inc.	Methods for improving liver clearance of xenobiotic substances in an animal
US20090176864A1 (en) *	2004-11-24	2009-07-09	Hill's Pet Nutrition, Inc.	Methods For Improving Hepatic and Immune Function In An Animal
CN101068480A (zh) *	2004-12-03	2007-11-07	爱科来株式会社	水溶性干燥食品
JP2008524123A (ja) *	2004-12-21	2008-07-10	クリティカルケアコネクションズインク	治療用栄養組成物又は組合せ、及びそれらの使用方法
DK1830883T3 (da) *	2004-12-29	2013-11-25	Hills Pet Nutrition Inc	Fremgangsmåde til at hæmme en nedgang i indlæring og/eller hukommelse hos dyr
US8647660B2 (en)	2004-12-29	2014-02-11	Hill's Pet Nutrition, Inc.	Combination of limited nutrients and enhanced dietary antioxidants to impart improved kidney health
US8252742B2 (en) *	2004-12-30	2012-08-28	Hill's Pet Nutrition, Inc.	Methods for enhancing the quality of life of a senior animal
US8148325B2 (en) *	2004-12-30	2012-04-03	Hill's Pet Nutrition, Inc.	Methods for enhancing the quality of life of a senior animal
US20070118295A1 (en) *	2005-03-02	2007-05-24	Al-Murrani Samer Waleed Khedhe	Methods and Systems for Designing Animal Food Compositions
US7198834B2 (en) *	2005-03-22	2007-04-03	Hewlett-Packard Development Company, L.P.	Imaging media including interference layer for generating human-readable marking on optical media
BRPI0610731A2 (pt) *	2005-04-19	2012-10-30	Hills Pet Nutrition Inc	composição, método para evitar ou tratar doença do rim, conjunto para a administração de uma composição de prevenção ou tratamento de doenças do rim ao paciente, método para a promoção da saúde do rim, meios para a comunicação de informação a respeito ou instruções para a mistura e a administração de uma ou mais das composições, componentes da composição, composições alimentìcias, ingredientes alimentìcios, e drogas renais, e para a utilização de dispositivos de diagnósticos renal da presente invenção, e, uso de uma composição
ATE512211T1 (de)	2005-05-31	2011-06-15	Iams Company	Feline probiotische lactobacilli
AU2006253007B2 (en)	2005-05-31	2012-12-20	Alimentary Health Ltd	Feline probiotic Bifidobacteria
US20090209647A1 (en) *	2005-06-14	2009-08-20	Nestec S.A.	Nutritional method
EP1906912B1 (de)	2005-07-14	2012-08-15	Hill's Pet Nutrition, Inc.	Verfahren zur verlängerung des lebens von tieren
US8492432B2 (en) *	2005-08-17	2013-07-23	Hill's Pet Nutrition, Inc.	Methods for the treatment of kidney disease
JP5220415B2 (ja) *	2005-09-06	2013-06-26	株式会社明治	老人性貧血を防止又は治療するためのアミノ酸組成物
US20090148426A1 (en)	2005-09-22	2009-06-11	Kaneka Corporation	Composition for life extension and method of extending the life
US8246946B2 (en) *	2005-09-27	2012-08-21	Cobb & Associates	Treatment of bipolar disorder utilizing anti-fungal compositions
US20070092577A1 (en) *	2005-10-03	2007-04-26	University Of Tennessee Research Foundation	Dietary calcium for reducing the production of reactive oxygen species
WO2007088046A2 (en) *	2006-02-01	2007-08-09	Nestec S.A.	Nutritional system and methods for increasing longevity
CA2642431A1 (en) *	2006-02-15	2007-08-23	Nestec S.A.	Use of bifidobacterium longum for the prevention and treatment of inflammation
US7960605B2 (en)	2006-03-17	2011-06-14	BioMaker Pharmaceuticals, Inc.	Methods for testing for caloric restriction (CR) mimetics
JP5264702B2 (ja) *	2006-03-29	2013-08-14	ネステクソシエテアノニム	プロバイオティクスを含有する栄養補助食品
WO2008007245A2 (en) *	2006-06-07	2008-01-17	The Iams Company	Natural preservatives for preservation of perishable products
ES2751020T3 (es) *	2006-06-08	2020-03-30	Iams Europe B V	Composición para mejorar la salud ocular
JP5281234B2 (ja) *	2006-06-27	2013-09-04	ポーラ化成工業株式会社	毛様体過緊張による疲れ目の改善・予防のための経口投与組成物
EP2036552B1 (de)	2006-07-05	2018-08-08	Kao Corporation	Seneszenz-inhibitor
JP2008013473A (ja) *	2006-07-05	2008-01-24	Kao Corp	筋機能低下抑制剤
EP2124966B1 (de)	2007-02-01	2015-09-09	IAMS Europe B.V.	Verfahren zur verringerung von entzündung und oxidativem stress bei einem säugetier mit glucose-antimetaboliten, avocado oder avocado-extrakten
US20090038024A1 (en) *	2007-06-19	2009-02-05	The Regents Of The University Of California	Cap/sorbs1 and diabetes
DE102007030495A1 (de) *	2007-06-30	2009-01-15	Alzchem Trostberg Gmbh	Verwendung einer eine Kreatin-Komponente enthaltende Zusammensetzung zur Verbesserung der Gedächtnisleistung, der Merkfähigkeit, des Langzeitgedächtnisses und zur Vorbeugung geistiger Ermüdungszustände
EP2022502A1 (de) *	2007-08-10	2009-02-11	Nestec S.A.	Lactobacillus rhamnosus und Gewichtssteuerung
US20100129467A9 (en)	2007-08-31	2010-05-27	Albritton Iv Ford D	Nutritional supplement
ES2716474T3 (es)	2007-10-26	2019-06-12	Avivagen Inc	Composiciones y métodos para mejorar la respuesta inmunitaria
JPWO2009066562A1 (ja) *	2007-11-20	2011-04-07	明治乳業株式会社	赤血球系幹細胞の分化促進剤及び／又は増殖促進剤、並びに老人性貧血を防止又は治療するためのメチオニンの使用及びメチオニンを含む組成物
AU2009210728B2 (en) *	2008-02-07	2014-06-19	Société des Produits Nestlé S.A.	Compositions and methods for influencing recovery from strenuous physical activity
AU2009233785B2 (en)	2008-04-11	2015-08-20	Berg Llc	Methods and use of inducing apoptosis in cancer cells
EP2123171A1 (de) *	2008-05-20	2009-11-25	Otto Thannesberger	Futtermischung
US9771199B2 (en) *	2008-07-07	2017-09-26	Mars, Incorporated	Probiotic supplement, process for making, and packaging
US9232813B2 (en) *	2008-07-07	2016-01-12	The Iams Company	Probiotic supplement, process for making, and packaging
CN102170792A (zh) *	2008-07-18	2011-08-31	希尔氏宠物营养品公司	提高老龄动物生活质量的方法
AU2009282482B2 (en) *	2008-08-15	2015-11-26	Société des Produits Nestlé S.A.	Methods for enhancing energy metabolism
US20100112136A1 (en) *	2008-10-30	2010-05-06	Susan Ruth Ward	Pet food composition comprising an antioxidant component
US20100112181A1 (en) *	2008-10-30	2010-05-06	Matthew Joel Taylor	Recovery of Antioxidants from Decaffeination Process
EP2216034A1 (de) *	2009-02-10	2010-08-11	Nestec S.A.	Lactobacillus-helveticus-CNCM I-4095 und Gewichtskontrolle
EP2216035A1 (de) *	2009-02-10	2010-08-11	Nestec S.A.	Lactobacillus-rhamnosus-CNCM I-4096 und Gewichtskontrolle
WO2010124391A1 (en) *	2009-04-30	2010-11-04	Chemaphor Inc.	Methods and compositions for improving the health of animals
AU2010247800A1 (en)	2009-05-11	2011-12-15	Berg Llc	Methods for the diagnosis of metabolic disorders using epimetabolic shifters, multidimensional intracellular molecules, or environmental influencers
US8691303B2 (en) *	2009-07-31	2014-04-08	The Iams Company	Dusted animal food
US10104903B2 (en)	2009-07-31	2018-10-23	Mars, Incorporated	Animal food and its appearance
US9210945B2 (en) *	2009-07-31	2015-12-15	The Iams Company	Animal food having low water activity
US20110027417A1 (en) *	2009-07-31	2011-02-03	Patrick Joseph Corrigan	Process for Dusting Animal Food
US9173423B2 (en) *	2009-07-31	2015-11-03	The Iams Company	Animal food kibble with electrostatically adhered dusting
CN102695428A (zh) *	2010-01-06	2012-09-26	雀巢产品技术援助有限公司	用于模拟热量限制的膳食方案
EP2444083A1 (de) *	2010-10-21	2012-04-25	Nestec S.A.	Cystein- und Nahrungsmittelaufnahme
CN103209596A (zh) *	2010-11-11	2013-07-17	雀巢产品技术援助有限公司	含有益生微生物的冷冻糖食
EP2452576A1 (de) *	2010-11-11	2012-05-16	Nestec S.A.	Extrudierte nicht-replizierende probiotische Mikroorganismen und ihre positiven Auswirkungen auf die Gesundheit
ES2708924T3 (es) *	2010-12-31	2019-04-12	Abbott Lab	Procedimientos de uso de oligosacáridos de la leche humana para mejorar la salud respiratoria de las vías respiratorias
CA2832324C (en)	2011-04-04	2022-03-15	Berg Llc	Methods of treating central nervous system tumors
EP2532355A1 (de) *	2011-06-06	2012-12-12	Nestec S.A.	Chicorée zur Vorbeugung und Behandlung von Neurodegeneration
CN107217051A (zh) *	2011-06-15	2017-09-29	Nse产品公司	识别热量限制标记物和热量限制模拟物
US8623924B2 (en)	2011-07-15	2014-01-07	Nusirt Sciences, Inc.	Compositions and methods for modulating metabolic pathways
SI2753311T1 (sl) *	2011-09-09	2020-12-31	Kemin Industries, Inc.	Formulacije antioksidanta
FR2982460B1 (fr) *	2011-11-14	2016-08-05	Virbac Sa	Produits pour administration orale comprenant des extraits de grenade punica granatum, destines a un animal de compagnie, et ses applications
US9198454B2 (en)	2012-03-08	2015-12-01	Nusirt Sciences, Inc.	Compositions, methods, and kits for regulating energy metabolism
WO2014027864A1 (ko) *	2012-08-16	2014-02-20	경희대학교 산학협력단	노화 및 치매의 예방 및/또는 치료 활성을 갖는 유산균
CN102783568B (zh) *	2012-08-29	2014-05-14	山东中医药大学	一种饲料添加剂
MX2015006023A (es)	2012-11-13	2016-03-31	Nusirt Sciences Inc	Composiciones y metodos para incrementar el metabolismo energetico.
AU2014225786B2 (en)	2013-03-08	2017-10-12	Axiom Foods, Inc.	Rice protein supplements
US9820504B2 (en)	2013-03-08	2017-11-21	Axiom Foods, Inc.	Rice protein supplement and methods of use thereof
CN105228627B (zh)	2013-03-15	2018-07-13	纽斯尔特科学公司	亮氨酸和烟酸降低脂质水平
WO2014149280A1 (en) *	2013-03-15	2014-09-25	Nusirt Sciences, Inc.	Treatment of pets with sirtuin activators
SG10201903112WA (en)	2013-04-08	2019-05-30	Berg Llc	Treatment of cancer using coenzyme q10 combination therapies
KR102370843B1 (ko)	2013-09-04	2022-03-04	버그 엘엘씨	코엔자임 q10의 연속주입에 의한 암치료 방법
CN103461674B (zh) *	2013-09-23	2014-12-31	大连圣弘医药有限公司	一种能够有效活化宠物关节的宠物功能食品配方及其制备方法
US20150164833A1 (en) *	2013-12-17	2015-06-18	Mead Johnson Nutrition Company	Nutritional composition containing a neurologic component of ursolic acid and uses thereof
EP3110507B1 (de)	2014-02-27	2020-11-18	NuSirt Sciences, Inc.	Zusammensetzungen und verfahren zur verringerung oder vorbeugung von lebersteatose
US20150335688A1 (en) *	2014-05-21	2015-11-26	Medlab Ip Pty Ltd	Probiotic combinations and uses thereof
CA2975219C (en)	2015-02-16	2022-02-22	Mars, Incorporated	Interlocking kibble
CN107529789A (zh)	2015-04-28	2018-01-02	马斯公司	制备灭菌湿宠物食品的方法
WO2017087576A1 (en)	2015-11-16	2017-05-26	Berg Llc	Methods of treatment of temozolomide-resistant glioma using coenzyme q10
EP3434783A4 (de)	2016-03-26	2019-11-06	Kawasaki Gakuen Educational Foundation	Mitochondrialer biomarker zur alterungsanzeige
USD805728S1 (en)	2016-09-06	2017-12-26	Mars, Incorporated	Food product
USD806351S1 (en)	2016-09-06	2018-01-02	Mars, Incorporated	Food product
IT201600111275A1 (it) *	2016-11-04	2018-05-04	Centro Dermatologico S R L	Metodo di trattamento cosmetico
GB201701417D0 (en)	2017-01-27	2017-03-15	Mars Inc	Pet food
US11284640B2 (en) *	2017-02-14	2022-03-29	University Of Southern California	Fasting mimicking diet
WO2018209131A1 (en)	2017-05-12	2018-11-15	Axiom Foods, Inc.	Rice products and systems and methods for making thereof
IT201800000890A1 (it) *	2018-01-15	2019-07-15	Sirt500 Sagl	Composizione nutraceutica per l’attivazione delle sirtuine con effetto anti-aging/reverse-aging
CN109045059A (zh) *	2018-08-01	2018-12-21	泓博元生命科技（深圳）有限公司	一种抗衰老、提高男性精力的组合物、制剂及其制备方法与应用
US12083152B2 (en)	2018-09-26	2024-09-10	Meiji Co., Ltd.	Agent for improving mitochondrial function
CN112955115B (zh)	2018-11-02	2023-06-30	联合利华知识产权控股有限公司	生物能烟酸甘油酯、组合物和使用其的方法
CA3119100C (en) *	2018-11-09	2024-06-04	Valter D. Longo	Nutrition bar for intermittent fasting-mimicking
EP3996668B1 (de) *	2019-07-12	2024-10-16	Unilever Global IP Limited	Topische zusammensetzungen und verfahren zur verwendung davon gegen mitochondriale fragmentierung
CN112079911B (zh) *	2020-09-04	2022-04-08	扬州大学	一种促进银杏类黄酮合成的关键基因GbMYB6及其表达的蛋白、载体和应用
CN112080507B (zh) *	2020-09-04	2022-04-08	扬州大学	一种调控银杏类黄酮合成的关键基因GbMYB4及其表达的蛋白、载体和应用
WO2022190120A1 (en) *	2021-03-12	2022-09-15	Thinking Forks Consulting Private Limited	Nutritional supplement composition for geriatric population and a method of producing the composition
US12557829B2 (en) *	2021-03-17	2026-02-24	Hyo Gyoung Yu	Liquid-phase, supplementary feed composition containing coenzyme Q10
CN116262121A (zh) *	2021-12-15	2023-06-16	南湖实验室	牛磺熊去氧胆酸及其钠盐在抗衰老和/或延长寿命中的应用
KR102779455B1 (ko) *	2024-09-03	2025-03-13	이대훈	반려동물의 눈 기능과 눈물자국 개선용 조성물 및 이를 포함하는 반려동물용 영양제

Family Cites Families (27)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
IT1156769B (it) *	1978-05-25	1987-02-04	Sigma Tau Ind Farmaceuti	Applicazione terapeutica della carnitina e di altri acil derivati della carnitina
US4330557A (en) *	1979-05-21	1982-05-18	Claudio Cavazza	Acyl-carnitine and use thereof in parenteral administration of triglycerides
US4921877A (en) *	1986-10-27	1990-05-01	Abbott Laboratories	Liquid nutritional formula for glucose intolerance
US4883672A (en) *	1988-04-29	1989-11-28	Shug Austin L	Method for preventing diet induced carnitine deficiency in domesticated dogs and cats
US5626849A (en) *	1995-06-07	1997-05-06	Reliv International, Inc.	Weight loss composition for burning and reducing synthesis of fats
FI104465B (fi) *	1995-06-14	2000-02-15	Valio Oy	Proteiinihydrolysaatteja allergioiden hoitamiseksi tai estämiseksi, niiden valmistus ja käyttö
US6022867A (en) *	1996-11-27	2000-02-08	Showa Denko Kabushiki Kaisha	Method of administering vitamin E to animals and compositions containing tocopheryl phosphates and salts thereof for animals
DK0969744T3 (da) *	1997-03-27	2003-06-23	Khursheed N Jeejeebhoy	Kosttilskud til forbedringer af celleenergetik
US6080788A (en) *	1997-03-27	2000-06-27	Sole; Michael J.	Composition for improvement of cellular nutrition and mitochondrial energetics
US5973004A (en) *	1997-04-04	1999-10-26	Howard; James R.	L-carnitine, acetyl-L-carnitine, and pantothenic acid or ubiquinone, combined for prevention and treatment of syndromes related to ineffective energy metabolism
FR2761887B1 (fr) *	1997-04-11	1999-06-18	Roland Asmar	Medicament visant a la prevention multifactorielle des maladies cardiovasculaires
US5916912A (en) *	1997-06-16	1999-06-29	The Regents Of The University Of California	Dietary composition for enhancing metabolism and alleviating oxidative stress
US5922766A (en) *	1997-07-02	1999-07-13	Acosta; Phyllis J. B.	Palatable elemental medical food
DE19806890A1 (de) *	1998-02-19	1999-08-26	Beiersdorf Ag	Kosmetische und dermatologische Wirkstoffkombinationen aus mindestens einer Substanz gewählt aus der Gruppe, bestehend aus Carnitin und den Acylcarnitinen, und mindestens einem Antioxidans sowie Zubereitungen mit einem Gehalt an solchen Wirkstoffkombinationen
US5926849A (en) *	1998-03-31	1999-07-27	Boyle; Kevin J.	Baseball cap with a channeled, laminated inside head band
US5932258A (en) *	1998-04-06	1999-08-03	The Iams Company	Composition and process for improving glucose metabolism in companion animals
IT1299191B1 (it) *	1998-06-23	2000-02-29	Sigma Tau Healthscience Spa	Composizione atta a prevenire e trattare l'osteoporosi e le alterazioni legate alla menopausa
IT1302307B1 (it) *	1998-09-01	2000-09-05	Sigma Tau Healthscience Spa	Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil
IT1304406B1 (it) *	1998-10-21	2001-03-19	Danital Italia S R L	Preparazione per la veicolazione di principi attivi basata su acidigrassi polinsaturi del gruppo omega 3.
US6562869B1 (en) *	1999-09-23	2003-05-13	Juvenon, Inc.	Nutritional supplement for increased energy and stamina
IT1306722B1 (it) *	1999-10-08	2001-10-02	Sigma Tau Healthscience Spa	Composizione per la prevenzione e/o il trattamento di disfunzionicircolatorie, comprendente derivati della l-carnitina ed estratti di
CA2389623A1 (en) *	1999-11-03	2001-05-10	Juvenon, Inc.	Method of treating benign forgetfulness
US20020146400A1 (en) *	2000-01-07	2002-10-10	Cincotta Anthony H.	Composition for reducing plasma triglycerides, platelet aggregation, and oxidative capacity
JP2003529347A (ja) *	2000-01-25	2003-10-07	ジュヴェノンインコーポレイテッド	高齢ペット用の栄養補給食品
US6277842B1 (en) *	2000-10-17	2001-08-21	James Alexander Carthron	Dietary supplemental method for fat and weight reduction
CA2498199C (en) *	2002-09-09	2012-01-17	Nestec S.A.	Orally administrable composition for improving hair and coat quality
JP2007519678A (ja) *	2004-01-28	2007-07-19	ネステクソシエテアノニム	皮膚状態を改良しそして皮膚病を予防するための栄養組成物

2002
- 2002-03-07 PL PL02363426A patent/PL363426A1/xx not_active Application Discontinuation
- 2002-03-07 KR KR10-2003-7011809A patent/KR20030088453A/ko not_active Ceased
- 2002-03-07 IL IL15736702A patent/IL157367A0/xx active IP Right Grant
- 2002-03-07 EA EA200300994A patent/EA006429B1/ru not_active IP Right Cessation
- 2002-03-07 MX MXPA03007802A patent/MXPA03007802A/es not_active Application Discontinuation
- 2002-03-07 WO PCT/EP2002/002862 patent/WO2002071874A2/en not_active Ceased
- 2002-03-07 CA CA002439078A patent/CA2439078C/en not_active Expired - Fee Related
- 2002-03-07 BR BR0207948-8A patent/BR0207948A/pt not_active IP Right Cessation
- 2002-03-07 JP JP2002570843A patent/JP2004519241A/ja active Pending
- 2002-03-07 CN CNA028062175A patent/CN1638650A/zh active Pending
- 2002-03-07 EP EP02750544A patent/EP1372412A2/de not_active Ceased
- 2002-03-08 PE PE2002000185A patent/PE20020987A1/es not_active Application Discontinuation
- 2002-03-08 AR ARP020100850A patent/AR032974A1/es unknown
2003
- 2003-08-12 IL IL157367A patent/IL157367A/en not_active IP Right Cessation
- 2003-09-05 NO NO20033941A patent/NO20033941D0/no not_active Application Discontinuation
- 2003-09-05 US US10/656,955 patent/US20040047896A1/en not_active Abandoned
- 2003-10-08 ZA ZA200307865A patent/ZA200307865B/en unknown
2004
- 2004-12-13 US US11/011,223 patent/US20050100617A1/en not_active Abandoned
2008
- 2008-03-20 AU AU2008201296A patent/AU2008201296A1/en not_active Abandoned

Also Published As

Publication number	Publication date
BR0207948A (pt)	2004-07-27
US20040047896A1 (en)	2004-03-11
WO2002071874A3 (en)	2003-01-09
EA200300994A1 (ru)	2004-02-26
NO20033941L (no)	2003-09-05
US20050100617A1 (en)	2005-05-12
EA006429B1 (ru)	2005-12-29
NO20033941D0 (no)	2003-09-05
AU2008201296A1 (en)	2008-04-17
IL157367A (en)	2006-07-05
IL157367A0 (en)	2004-02-19
CA2439078C (en)	2009-08-25
KR20030088453A (ko)	2003-11-19
CN1638650A (zh)	2005-07-13
JP2004519241A (ja)	2004-07-02
CA2439078A1 (en)	2002-09-19
WO2002071874A2 (en)	2002-09-19
MXPA03007802A (es)	2003-12-08
EP1372412A2 (de)	2004-01-02
PL363426A1 (en)	2004-11-15
AR032974A1 (es)	2003-12-03
PE20020987A1 (es)	2002-12-17

Publication	Publication Date	Title
CA2439078C (en)	2009-08-25	Composition improving age-related physiological deficits and increasing longevity
CN1917779B (zh)	2010-06-16	用于改善皮肤状况和防止皮肤病的营养组合物
EP1213970B1 (de)	2008-06-11	Verfahren zur verbesserung der haut und des pelzes von haustieren
EP1492415B2 (de)	2019-11-13	Verfahren zum verbessern der absorption von vitamin e bei tieren
NO330469B1 (no)	2011-04-18	Naeringssammensetning og anvendelse av denne.
EP1637041B1 (de)	2008-04-30	Verbesserung der Lebensdauer alter Katzen
EP3537889B1 (de)	2021-09-29	Tiernahrungszusammensetzungen
AU2002308162A1 (en)	2002-09-24	Composition improving age-related physiological deficits and increasing longevity
HK1080688A (en)	2006-05-04	Composition improving age-related physiological deficits and increasing longevity
MXPA06008544A (en)	2007-04-10	Nutritional composiition for improving skin condition and preventing skin diseases
HK1098017A (en)	2007-07-13	Nutritional composition for improving skin condition and preventing skin diseases