ZA200607042B - Phospholipid analogs for diagnosis and treatment of cancer - Google Patents

Phospholipid analogs for diagnosis and treatment of cancer Download PDF

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Publication number
ZA200607042B
ZA200607042B ZA200607042A ZA200607042A ZA200607042B ZA 200607042 B ZA200607042 B ZA 200607042B ZA 200607042 A ZA200607042 A ZA 200607042A ZA 200607042 A ZA200607042 A ZA 200607042A ZA 200607042 B ZA200607042 B ZA 200607042B
Authority
ZA
South Africa
Prior art keywords
cancer
tumor
para
group
iodine
Prior art date
Application number
ZA200607042A
Other languages
English (en)
Inventor
Weichert Jamey
Longino Marc
Pinchuk Anatoly
Original Assignee
Cellectar Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellectar Llc filed Critical Cellectar Llc
Publication of ZA200607042B publication Critical patent/ZA200607042B/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0489—Phosphates or phosphonates, e.g. bone-seeking phosphonates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0404—Lipids, e.g. triglycerides; Polycationic carriers
    • A61K51/0408—Phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/575—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/5758—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites
    • G01N33/5759—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumours, cancers or neoplasias, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides or metabolites involving compounds localised on the membrane of tumour or cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/001—Preparation for luminescence or biological staining
    • A61K49/0013—Luminescence
    • A61K49/0017—Fluorescence in vivo
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Epidemiology (AREA)
  • Optics & Photonics (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Food Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA200607042A 2004-03-02 2006-08-23 Phospholipid analogs for diagnosis and treatment of cancer ZA200607042B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52116604P 2004-03-02 2004-03-02

Publications (1)

Publication Number Publication Date
ZA200607042B true ZA200607042B (en) 2007-12-27

Family

ID=34919310

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200607042A ZA200607042B (en) 2004-03-02 2006-08-23 Phospholipid analogs for diagnosis and treatment of cancer

Country Status (16)

Country Link
US (3) US8535641B2 (de)
EP (3) EP2044961B1 (de)
JP (7) JP2007528374A (de)
KR (1) KR20070015518A (de)
CN (1) CN1929869B (de)
AT (1) ATE437657T1 (de)
AU (1) AU2005219412A1 (de)
BR (1) BRPI0508425A (de)
CA (1) CA2557698A1 (de)
DE (1) DE602005015687D1 (de)
DK (1) DK1729824T3 (de)
ES (3) ES2430065T3 (de)
IL (1) IL177645A0 (de)
MX (1) MXPA06009681A (de)
WO (1) WO2005084716A2 (de)
ZA (1) ZA200607042B (de)

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US11311576B2 (en) 2018-01-22 2022-04-26 Seattle Children's Hospital Methods of use for CAR T cells
US12312416B2 (en) 2018-02-06 2025-05-27 Seattle Children's Hospital Fluorescein-specific cars exhibiting optimal t cell function against FL-PLE labelled tumors
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CA3095515A1 (en) 2018-04-10 2019-10-17 Cellectar Biosciences, Inc. Phospholipid-flavagline conjugates and methods of using the same for targeted cancer therapy
BR112022006739B1 (pt) 2019-10-10 2024-01-23 Cellectar Biosciences, Inc Conjugados fosfolipídio-flavagina e métodos de uso do mesmo para terapia direcionada a câncer
US20240131204A1 (en) * 2019-10-10 2024-04-25 Cellectar Biosciences, Inc. Fractionated Dosing of a Phospholipid Ether Analog for the Treatment of Cancer
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US8022235B2 (en) * 2007-06-01 2011-09-20 Cellectar, Inc. Compositions of phospholipid ether boronic acids and esters and methods for their synthesis and use
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Also Published As

Publication number Publication date
US8877159B2 (en) 2014-11-04
IL177645A0 (en) 2006-12-31
DK1729824T3 (da) 2009-11-02
US8535641B2 (en) 2013-09-17
HK1130186A1 (en) 2009-12-24
JP2013040201A (ja) 2013-02-28
EP2044960A3 (de) 2009-11-04
EP2044961A3 (de) 2009-08-12
JP6228080B2 (ja) 2017-11-08
EP1729824B1 (de) 2009-07-29
US9550002B2 (en) 2017-01-24
JP2015071642A (ja) 2015-04-16
CN1929869B (zh) 2010-11-24
US20150093330A1 (en) 2015-04-02
ES2430065T3 (es) 2013-11-18
JP2014210803A (ja) 2014-11-13
JP2017002060A (ja) 2017-01-05
ATE437657T1 (de) 2009-08-15
EP2044961A2 (de) 2009-04-08
EP2044961B1 (de) 2013-07-17
CA2557698A1 (en) 2005-09-15
KR20070015518A (ko) 2007-02-05
US20140023587A1 (en) 2014-01-23
JP6342818B2 (ja) 2018-06-13
DE602005015687D1 (de) 2009-09-10
US20050196339A1 (en) 2005-09-08
JP6453818B2 (ja) 2019-01-16
EP2044960A2 (de) 2009-04-08
AU2005219412A1 (en) 2005-09-15
JP2012097113A (ja) 2012-05-24
EP1729824A2 (de) 2006-12-13
BRPI0508425A (pt) 2007-07-24
JP2007528374A (ja) 2007-10-11
EP2044960B1 (de) 2013-11-20
CN1929869A (zh) 2007-03-14
JP2017173339A (ja) 2017-09-28
WO2005084716A2 (en) 2005-09-15
WO2005084716A3 (en) 2006-06-01
ES2440257T3 (es) 2014-01-28
MXPA06009681A (es) 2007-03-15
ES2330951T3 (es) 2009-12-17

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