ZA200701856B - Novel carbonyl reductase, gene therefor and method of using the same - Google Patents

Novel carbonyl reductase, gene therefor and method of using the same Download PDF

Info

Publication number: ZA200701856B
Authority: ZA; South Africa
Prior art keywords: polypeptide; phenyl; tert; chloro; butoxycarbonylamino
Prior art date: 2004-08-06

Application number

ZA200701856A

Other languages

English (en)

Inventor

Kizaki Noriyuki

Yano Miho

Funaki Masahiro

Takesue Teruaki

Yasohara Yoshihiko

Morikawa Souichi

Nakai Takahisa

Michihiko Kataoka

Shimuzu Sakayu

Original Assignee

Kaneka Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2004-08-06

Filing date

2005-08-01

Publication date

2008-07-30

2005-08-01 Application filed by Kaneka Corp filed Critical Kaneka Corp

2008-07-30 Publication of ZA200701856B publication Critical patent/ZA200701856B/en

Links

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Classifications

- C—CHEMISTRY; METALLURGY
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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ZA200701856A 2004-08-06 2005-08-01 Novel carbonyl reductase, gene therefor and method of using the same ZA200701856B (en)

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JP2004231226		2004-08-06

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ZA200701856A ZA200701856B (en)	2004-08-06	2005-08-01	Novel carbonyl reductase, gene therefor and method of using the same

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US (2)	US7794993B2 (de)
EP (1)	EP1792986B1 (de)
JP (1)	JP4746548B2 (de)
KR (1)	KR20070050461A (de)
CN (1)	CN1993464B (de)
AT (1)	ATE419340T1 (de)
DE (1)	DE602005012127D1 (de)
ES (1)	ES2317277T3 (de)
WO (1)	WO2006013801A1 (de)
ZA (1)	ZA200701856B (de)

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AT501928B1 (de) *	2004-10-27	2010-09-15	Iep Gmbh	Verfahren zur herstellung von chiralen alkoholen
EP1995314B1 (de)	2006-03-31	2011-10-19	Kaneka Corporation	Verfahren zur produktion von erythro- oder threo-2-amino-3-hydroxypropionsäureester, neuartige carbonylreduktase, gen für die reduktase, vektor, transformante und verfahren zur produktion von optisch aktivem alkohol unter verwendung dieser
GB0619240D0 (en) *	2006-09-29	2006-11-08	Almac Sciences Ltd	Reduction of alpha-halo ketones
ES2424960T3 (es) *	2007-12-27	2013-10-10	Otsuka Pharmaceutical Co., Ltd.	Enzima asociado a la síntesis de ecuol
DK2446025T3 (en)	2009-06-22	2018-10-22	Codexis Inc	: KETOREDUCTASE-MEDIATED STEREOSELECTIVE ROAD TO ALFA CHLORAL ALCOHOLS
US9080192B2 (en)	2010-02-10	2015-07-14	Codexis, Inc.	Processes using amino acid dehydrogenases and ketoreductase-based cofactor regenerating system
JP5941410B2 (ja)	2010-11-09	2016-06-29	株式会社カネカ	ハロゲン化インデノン類及びそれを用いた光学活性インダノン類又は光学活性インダノール類の製造方法
CN102732579A (zh) *	2011-04-01	2012-10-17	浙江九洲药业股份有限公司	一种微生物转化制备(3s)-3-(叔丁氧羰基)氨基-1-氯-4-苯基-(2r)-丁醇的方法
CN103695443B (zh) *	2014-01-12	2015-12-09	中国科学院成都生物研究所	一种新型羰基还原酶、其基因及应用
CN103740668B (zh) *	2014-01-17	2016-02-10	江苏八巨药业有限公司	一种提高葡萄糖脱氢酶释放量的方法
CN105821013B (zh) *	2016-04-05	2019-05-03	华东理工大学	羰基还原酶及其在制备手性n-保护-羟基氮杂环中的应用
CN110387361A (zh) *	2019-08-12	2019-10-29	天津迪沙医药技术开发有限公司	一种醛酮还原酶及其应用
CN114729374B (zh) *	2019-11-22	2024-12-17	株式会社Api	羰基还原酶、编码该酶的核酸、以及利用它们的光学活性化合物的制造方法
CN111635893A (zh) *	2020-07-07	2020-09-08	南京朗恩生物科技有限公司	一种酮还原酶及其在达芦那韦中间体生产中的应用
CN111662889B (zh) *	2020-07-07	2022-03-04	南京朗恩生物科技有限公司	一种用于生产达芦那韦中间体的酮还原酶突变体
CN111690696B (zh) *	2020-07-07	2021-12-31	南京朗恩生物科技有限公司	一种生物催化制备达芦那韦中间体的方法
CN113249348B (zh) *	2021-05-19	2023-06-23	华东理工大学	羰基还原酶、其基因、含有该基因的重组表达转化体及其应用

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SE519261C2 (sv)	2001-07-17	2003-02-04	Sca Hygiene Prod Ab	Absorberande alster
WO2003078634A1 (en)	2002-03-19	2003-09-25	Mitsubishi Chemical Corporation	Novel carbonyl reductase, gene encoding it and process for producing optically active alcohols using the same
JP4270918B2 (ja)	2002-03-19	2009-06-03	三菱化学株式会社	新規カルボニル還元酵素及びこれをコードする遺伝子、ならびにこれらを利用した光学活性アルコールの製造方法
JP2004254554A (ja)	2003-02-25	2004-09-16	Mitsubishi Chemicals Corp	光学活性２−メトキシ−１−（４−トリフルオロメチル−フェニル）エタノールの製造方法

2005
- 2005-08-01 US US11/659,481 patent/US7794993B2/en not_active Expired - Fee Related
- 2005-08-01 KR KR1020077005277A patent/KR20070050461A/ko not_active Withdrawn
- 2005-08-01 ES ES05767288T patent/ES2317277T3/es not_active Expired - Lifetime
- 2005-08-01 ZA ZA200701856A patent/ZA200701856B/en unknown
- 2005-08-01 DE DE602005012127T patent/DE602005012127D1/de not_active Expired - Lifetime
- 2005-08-01 EP EP05767288A patent/EP1792986B1/de not_active Expired - Lifetime
- 2005-08-01 CN CN2005800266432A patent/CN1993464B/zh not_active Expired - Fee Related
- 2005-08-01 JP JP2006531447A patent/JP4746548B2/ja not_active Expired - Fee Related
- 2005-08-01 WO PCT/JP2005/014006 patent/WO2006013801A1/ja not_active Ceased
- 2005-08-01 AT AT05767288T patent/ATE419340T1/de active
2010
- 2010-07-20 US US12/840,026 patent/US7915022B2/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
ES2317277T3 (es)	2009-04-16
JPWO2006013801A1 (ja)	2008-05-01
ATE419340T1 (de)	2009-01-15
US20100317075A1 (en)	2010-12-16
CN1993464B (zh)	2011-12-28
EP1792986A4 (de)	2007-09-12
DE602005012127D1 (de)	2009-02-12
US20080261281A1 (en)	2008-10-23
US7794993B2 (en)	2010-09-14
US7915022B2 (en)	2011-03-29
WO2006013801A1 (ja)	2006-02-09
JP4746548B2 (ja)	2011-08-10
EP1792986A1 (de)	2007-06-06
KR20070050461A (ko)	2007-05-15
EP1792986B1 (de)	2008-12-31
CN1993464A (zh)	2007-07-04

Publication	Publication Date	Title
US7915022B2 (en)	2011-03-29	Carbonyl reductase, gene thereof and method of using the same
JP4510351B2 (ja)	2010-07-21	新規カルボニル還元酵素、その遺伝子、およびその利用法
US20130149769A1 (en)	2013-06-13	Novel carbonyl reductase, gene therefor and use thereof
JPWO2007094178A1 (ja)	2009-07-02	新規な（ｓ，ｓ）−ブタンジオール脱水素酵素、その遺伝子、及びその利用法
WO2007114217A1 (ja)	2007-10-11	エリスロ又はスレオ－２－アミノ－３－ヒドロキシプロピオン酸エステルの製造方法、新規カルボニル還元酵素、その遺伝子、ベクター、形質転換体、およびそれらを利用した光学活性アルコールの製造方法
JP4414337B2 (ja)	2010-02-10	新規カルボニル還元酵素、その遺伝子、およびその利用法
JP5308163B2 (ja)	2013-10-09	新規アルコール脱水素酵素、その遺伝子、ベクター、形質転換体、およびそれらを利用した光学活性アルコールの製造方法
JP4426437B2 (ja)	2010-03-03	新規カルボニル還元酵素、その遺伝子、およびその利用法
JP5761641B2 (ja)	2015-08-12	（ｒ）−３−キヌクリジノールの製造方法
JP5005672B2 (ja)	2012-08-22	新規カルボニル還元酵素、その遺伝子、およびそれらを利用した光学活性アルコールの製造方法
US9783796B2 (en)	2017-10-10	Amidase, gene for the same, vector, transformant, and method for production of optically active carboxylic acid amide and optically active carboxylic acid by using any one of those items
JP4880859B2 (ja)	2012-02-22	新規カルボニル還元酵素、その遺伝子、およびその利用法
JPWO2002010399A1 (ja)	2003-09-09	新規カルボニル還元酵素、その遺伝子、およびその利用法
US20080305534A1 (en)	2008-12-11	Novel Glycerol Dehydrogenase, Gene Therefor, and Method of Utilizing the Same
JP4796323B2 (ja)	2011-10-19	新規カルボニル還元酵素、その遺伝子、およびその利用法
JP2005102511A (ja)	2005-04-21	新規アルコール脱水素酵素、その遺伝子
JP2003061668A (ja)	2003-03-04	新規グリセロール脱水素酵素およびその利用法
JP2010279272A (ja)	2010-12-16	新規カルボニル還元酵素、その遺伝子、ベクター、形質転換体、およびそれらを利用した光学活性アルコールの製造方法
WO2010123067A1 (ja)	2010-10-28	(ｓ)-１-置換プロパン-１-オール誘導体の製造方法
WO2008047819A1 (fr)	2008-04-24	Nouvelle ester hydrolase, gène codant pour ladite enzyme et utilisation