ZA200902183B - Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof - Google Patents

Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof

Info

Publication number
ZA200902183B
ZA200902183B ZA200902183A ZA200902183A ZA200902183B ZA 200902183 B ZA200902183 B ZA 200902183B ZA 200902183 A ZA200902183 A ZA 200902183A ZA 200902183 A ZA200902183 A ZA 200902183A ZA 200902183 B ZA200902183 B ZA 200902183B
Authority
ZA
South Africa
Prior art keywords
salts
bis
preparation
piperidylmethyl
trifluoroethoxy
Prior art date
Application number
ZA200902183A
Other languages
English (en)
Inventor
Reine Inese
Zandersons Armands
Original Assignee
Grindeks
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Grindeks filed Critical Grindeks
Publication of ZA200902183B publication Critical patent/ZA200902183B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/225—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing halogen
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/09—Preparation of ethers by dehydration of compounds containing hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/205—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring
    • C07C43/2055—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring the aromatic ring being a non-condensed ring containing more than one ether bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Catalysts (AREA)
ZA200902183A 2006-11-06 2009-04-16 Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof ZA200902183B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP06123547A EP1918280A1 (de) 2006-11-06 2006-11-06 Verfahren zur Herstellung von 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamid und dessen Salze

Publications (1)

Publication Number Publication Date
ZA200902183B true ZA200902183B (en) 2010-07-28

Family

ID=37965028

Family Applications (2)

Application Number Title Priority Date Filing Date
ZA200902183A ZA200902183B (en) 2006-11-06 2009-04-16 Process for the preparation of 2,5-bis-(2,2,2-trifluoroethoxy)-N-(2-piperidylmethyl)-benzamide and salts thereof
ZA200902184A ZA200902184B (en) 2006-11-06 2009-04-16 Process for the preparation of trifluoroethoxytoluenes

Family Applications After (1)

Application Number Title Priority Date Filing Date
ZA200902184A ZA200902184B (en) 2006-11-06 2009-04-16 Process for the preparation of trifluoroethoxytoluenes

Country Status (14)

Country Link
US (2) US20100063292A1 (de)
EP (3) EP1918280A1 (de)
JP (2) JP2010508331A (de)
KR (2) KR20090064456A (de)
CN (2) CN101516817A (de)
AT (1) ATE514670T1 (de)
AU (2) AU2007316690A1 (de)
BR (2) BRPI0714991A2 (de)
CA (2) CA2660364A1 (de)
EA (2) EA200900356A1 (de)
MX (2) MX2009004648A (de)
PL (1) PL2079674T3 (de)
WO (2) WO2008055849A1 (de)
ZA (2) ZA200902183B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102977003A (zh) * 2012-11-28 2013-03-20 郑州大明药物科技有限公司 醋酸氟卡胺的制备方法
CN111018694A (zh) * 2019-12-12 2020-04-17 贵州省欣紫鸿药用辅料有限公司 一种氟卡尼的生产方法
CN115368786B (zh) * 2022-08-15 2023-05-09 江阴市华昌不锈钢管有限公司 一种超级奥氏体耐高温、耐腐蚀不锈钢焊管的制备工艺
CN116120146B (zh) * 2022-08-18 2024-01-16 浙江省化工研究院有限公司 一种六氟丁二烯的生产方法和系统
CN117385378B (zh) * 2023-10-13 2024-09-24 厦门大学 一种缺电子芳香缩醛的电氧化制备方法和应用

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3900481A (en) * 1974-04-01 1975-08-19 Riker Laboratories Inc Derivatives of pyrrolidine and piperidine
US4617396A (en) * 1979-03-19 1986-10-14 Riker Laboratories, Inc. Process for the preparation of derivatives of piperidine
IL120715A (en) * 1997-04-21 2000-07-16 Finetech Ltd Process for the preparation of (2,2,2,-trifluoroethoxy)benzoic acids
DE10025700A1 (de) * 2000-05-26 2001-11-29 Merck Patent Gmbh Verfahren zur Herstellung von trifluorethoxysubstituierten Benzoesäuren
US6458957B1 (en) * 2000-07-12 2002-10-01 Geneva Pharmaceuticals, Inc. α,α-dibromo-α-chloro-acetophenones as synthons
ITMI20011772A1 (it) * 2001-08-10 2003-02-10 A M S A Anonima Materie Sint E Processo per la preparazione della 2,5-bis-(2,2,2-trifluoroetossi)-n-(2-piperidilmetil)-benzamide(flecainide)
US7196197B2 (en) * 2003-09-17 2007-03-27 Apotex Pharmachem Inc. Process for the preparation of Flecainide, its pharmaceutically acceptable salts and important intermediates thereof

Also Published As

Publication number Publication date
US20100063292A1 (en) 2010-03-11
EP2079674A1 (de) 2009-07-22
WO2008055849A1 (en) 2008-05-15
JP2010508331A (ja) 2010-03-18
MX2009004647A (es) 2009-05-20
BRPI0714991A2 (pt) 2013-07-30
AU2007316692A1 (en) 2008-05-15
CN101516817A (zh) 2009-08-26
EP2079692A1 (de) 2009-07-22
EP1918280A1 (de) 2008-05-07
WO2008055851A8 (en) 2009-04-09
US20100056794A1 (en) 2010-03-04
KR20090055638A (ko) 2009-06-02
PL2079674T3 (pl) 2011-11-30
CA2660364A1 (en) 2008-05-15
WO2008055851A1 (en) 2008-05-15
EA200900357A1 (ru) 2009-10-30
BRPI0714989A2 (pt) 2013-07-30
MX2009004648A (es) 2009-05-21
KR20090064456A (ko) 2009-06-18
CA2660358A1 (en) 2008-05-15
JP2010508330A (ja) 2010-03-18
ATE514670T1 (de) 2011-07-15
ZA200902184B (en) 2010-03-31
EA200900356A1 (ru) 2009-10-30
EP2079674B1 (de) 2011-06-29
AU2007316690A1 (en) 2008-05-15
CN101516845A (zh) 2009-08-26

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