ZA201408064B - Prodrugs of anti-platelet agents - Google Patents

Prodrugs of anti-platelet agents

Info

Publication number
ZA201408064B
ZA201408064B ZA2014/08064A ZA201408064A ZA201408064B ZA 201408064 B ZA201408064 B ZA 201408064B ZA 2014/08064 A ZA2014/08064 A ZA 2014/08064A ZA 201408064 A ZA201408064 A ZA 201408064A ZA 201408064 B ZA201408064 B ZA 201408064B
Authority
ZA
South Africa
Prior art keywords
prodrugs
platelet agents
platelet
agents
Prior art date
Application number
ZA2014/08064A
Other languages
English (en)
Inventor
Mahesh Kandula
Original Assignee
Cellix Bio Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Cellix Bio Private Ltd filed Critical Cellix Bio Private Ltd
Publication of ZA201408064B publication Critical patent/ZA201408064B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/72Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA2014/08064A 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents ZA201408064B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IN1781CH2012 2012-05-07
PCT/IB2013/052328 WO2013168024A1 (fr) 2012-05-07 2013-03-24 Promédicaments d'agents antiplaquettaires

Publications (1)

Publication Number Publication Date
ZA201408064B true ZA201408064B (en) 2016-04-28

Family

ID=54193687

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA2014/08064A ZA201408064B (en) 2012-05-07 2014-11-04 Prodrugs of anti-platelet agents

Country Status (8)

Country Link
EP (1) EP2847197A4 (fr)
JP (1) JP2015519334A (fr)
CN (1) CN104379589A (fr)
AU (1) AU2013257745A1 (fr)
CA (1) CA2873094A1 (fr)
SG (1) SG11201407307YA (fr)
WO (1) WO2013168024A1 (fr)
ZA (1) ZA201408064B (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2873018A1 (fr) * 2012-07-03 2014-01-09 Cellixbio Private Limited Compositions et methodes de traitement de la douleur moderee a aigue
JP2023535815A (ja) * 2020-07-29 2023-08-21 シャンハイ キュアジーン ファーマシューティカル カンパニー,リミテッド 抗血小板薬およびその使用
CN114507157B (zh) * 2020-11-17 2023-03-24 沧州维智达美制药有限公司 一种利用氯乙腈制备溴乙腈的方法
CN119019320B (zh) * 2024-10-29 2025-03-11 上海柯君医药科技有限公司 一种具有抗血小板活性的哌啶类化合物的制备方法

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6858734B2 (en) * 2003-04-23 2005-02-22 Rhodia Pharma Solutions Inc. Preparation of (S)-Clopidogrel and related compounds
CA2534342C (fr) * 2003-07-29 2016-05-10 V. Ravi Chandran Prodrogues a base d'acides amines
BRPI0610311A2 (pt) * 2005-05-27 2010-06-15 Daiichi Sankyo Co Ltd derivado de amina cìclica tendo grupo alquila substituìdo
KR100990949B1 (ko) * 2008-06-09 2010-10-29 엔자이텍 주식회사 클로피도그렐 및 그의 유도체의 제조방법
CN102002053A (zh) * 2009-09-02 2011-04-06 陕西合成药业有限公司 用于治疗的四氢噻吩并吡啶衍生物
CN102336767A (zh) * 2011-07-11 2012-02-01 华东理工大学 制备高纯度手性α-取代-6,7-二氢噻吩并[3,2-c]吡啶衍生物的方法
WO2013024376A1 (fr) * 2011-08-16 2013-02-21 Mahesh Kandula Compositions et procédés pour le traitement de l'athérotrombose
US9525998B2 (en) * 2012-01-06 2016-12-20 Qualcomm Incorporated Wireless display with multiscreen service
KR102524731B1 (ko) * 2012-01-27 2023-04-21 인터디지탈 패튼 홀딩스, 인크 다중 캐리어 기반형 및/또는 의사 조합형 네트워크에서 epdcch를 제공하는 시스템 및/또는 방법
SG11201407300VA (en) * 2012-05-07 2014-12-30 Cellix Bio Private Ltd Compositions and methods for the treatment of neurological disorders
JP2015526385A (ja) * 2012-05-08 2015-09-10 セリックスビオ プライヴェート リミテッド てんかんの治療のための組成物及び方法
AU2013257710B2 (en) * 2012-05-08 2016-10-20 Cellixbio Private Limited Compositions and methods for the treatment of neurological disorders
CN104364241A (zh) * 2012-05-08 2015-02-18 塞利克斯比奥私人有限公司 抑制碳酸酐酶活性的组合物和方法
CA2873084A1 (fr) * 2012-05-08 2013-11-14 Cellixbio Private Limited Compositions et methodes de traitement du diabete
CA2873018A1 (fr) * 2012-07-03 2014-01-09 Cellixbio Private Limited Compositions et methodes de traitement de la douleur moderee a aigue

Also Published As

Publication number Publication date
WO2013168024A1 (fr) 2013-11-14
JP2015519334A (ja) 2015-07-09
AU2013257745A1 (en) 2014-11-27
SG11201407307YA (en) 2014-12-30
CA2873094A1 (fr) 2013-11-14
EP2847197A4 (fr) 2015-11-04
CN104379589A (zh) 2015-02-25
EP2847197A1 (fr) 2015-03-18

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