ZA753722B - Process for the preparation of analogues of daunomycin - Google Patents

Process for the preparation of analogues of daunomycin

Info

Publication number: ZA753722B
Authority: ZA; South Africa
Prior art keywords: daunomycin; analogues; preparation
Prior art date: 1974-06-12

Application number

ZA00753722A

Other languages

English (en)

Inventor

L Bernardi

F Arcamone

B Patelli

Marco A Di

Original Assignee

Farmaceutici Italia

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1974-06-12

Filing date

1975-06-10

Publication date

1976-09-29

1975-06-10 Application filed by Farmaceutici Italia filed Critical Farmaceutici Italia

1976-09-29 Publication of ZA753722B publication Critical patent/ZA753722B/xx

Links

STQGQHZAVUOBTE-VGBVRHCVSA-N daunorubicin Chemical class O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(C)=O)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 STQGQHZAVUOBTE-VGBVRHCVSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/252—Naphthacene radicals, e.g. daunomycins, adriamycins

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Biochemistry (AREA)
Biotechnology (AREA)
General Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Saccharide Compounds (AREA)

ZA00753722A 1974-06-12 1975-06-10 Process for the preparation of analogues of daunomycin ZA753722B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
GB2608374A GB1467383A (en)	1974-06-12	1974-06-12	Daunomycin analogues

Publications (1)

Publication Number	Publication Date
ZA753722B true ZA753722B (en)	1976-09-29

Family

ID=10238087

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA00753722A ZA753722B (en)	1974-06-12	1975-06-10	Process for the preparation of analogues of daunomycin

Country Status (17)

Country	Link
US (1)	US4046878A (fr)
JP (1)	JPS5840557B2 (fr)
AT (1)	AT337363B (fr)
BE (1)	BE830090A (fr)
BG (1)	BG61059B2 (fr)
CH (1)	CH611317A5 (fr)
DE (2)	DE2525633A1 (fr)
DK (1)	DK147304C (fr)
ES (1)	ES438431A1 (fr)
FR (1)	FR2274629A1 (fr)
GB (1)	GB1467383A (fr)
HK (1)	HK982A (fr)
MY (1)	MY103666A (fr)
NL (1)	NL173272C (fr)
SE (1)	SE423633B (fr)
SU (1)	SU645588A3 (fr)
ZA (1)	ZA753722B (fr)

Families Citing this family (44)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1506200A (en) *	1975-04-30	1978-04-05	Farmaceutici Italia	Glycosides
GB1509875A (en) *	1976-06-14	1978-05-04	Farmaceutici Italia	Optically active anthracyclinones and anthracycline glycosides
US4161480A (en) *	1978-06-05	1979-07-17	G. D. Searle & Co.	Intermediates for the synthesis of 4-demethoxydaunorubicin
US4201773A (en) *	1978-07-26	1980-05-06	The United States Of America As Represented By The Department Of Health, Education And Welfare	7-O-(2,6-Dideoxy-α-L-lyxo-hexopyranosyl)-daunomycinone, desmethoxy daunomycinone, adriamycinone, and carminomycinone
IL55431A (en) *	1978-08-24	1982-07-30	Yeda Res & Dev	Anthracycline type antibiotics,their preparation and pharmaceutical compositions comprising them
NL8001417A (nl) *	1979-03-17	1980-09-19	Erba Farmitalia	Antitumorglycosiden.
BE884828A (fr) *	1979-08-20	1981-02-19	Hoffmann La Roche	Derives de naphtacene
CA1154013A (fr) *	1979-09-01	1983-09-20	Alberto Bargiotti	Glycosides antitumoraux, leur preparation leur utilisation et les compositions les renfermant
DE3100968A1 (de) *	1980-01-16	1982-01-14	Farmitalia Carlo Erba S.p.A., 20159 Milano	Anthracyclinderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
US4348388A (en) *	1980-04-02	1982-09-07	G.D. Searle & Co.	11-Amino-11-deoxydaunorubicin and analogs
ZA814722B (en) *	1980-07-18	1982-07-28	Hoffmann La Roche	Novel anthracycline glycosides
IT1210476B (it) *	1981-05-28	1989-09-14	Erba Farmitalia	Antracicline.
GB8317037D0 (en) *	1983-06-23	1983-07-27	Erba Farmitalia	6-deoxyanthracyclines
US5138042A (en) *	1981-05-28	1992-08-11	Farmitalia Carlo Erba S.P.A.	6-deoxyanthracyclines
US4563444A (en) *	1982-05-26	1986-01-07	Farmitalia Carlo Erba S.P.A.	Anthracycline glycosides, use and compositions containing same
US4604381A (en) *	1982-07-16	1986-08-05	Farmitalia Carlo Erba S.P.A.	4-demethoxy-13-dihydrodaunorubicin and use thereof
US4562177A (en) *	1982-08-17	1985-12-31	The Ohio State University Research Foundation	3'-Amino-2' halo-anthracycline antibiotics
US4564674A (en) *	1983-10-31	1986-01-14	Sagami Chemical Research Center	Process for an anthracycline derivative, and an anthracyclinone derivative useful for the process
US4496485A (en) *	1983-11-25	1985-01-29	G. D. Searle & Co.	Asymmetric 7-O-(substituted acetyl)-4-demethoxydaunomycinones
US4537882A (en) *	1984-05-10	1985-08-27	Ohio State University	4-Demethoxy-3'-desamino-2'-halo-anthracycline and pharmaceutical composition containing same
US4697005A (en) *	1985-03-20	1987-09-29	Ohio State University Research Foundation	1-fluoro, 4-fluoro, and 1,4-difluoro anthracycline anticancer antibiotics
US5124317A (en) *	1985-08-02	1992-06-23	Farmitalia Carlo Erba S.P.A.	Injectable ready-to-use solutions containing an antitumor anthracycline glycoside
NZ224252A (en) *	1987-04-21	1991-09-25	Erba Carlo Spa	An anthracycline glycoside and its preparation
JPS63191263U (fr) *	1987-05-29	1988-12-09
GB2212154B (en) *	1987-11-10	1991-03-27	Erba Carlo Spa	New 4-demethoxy anthracycline derivatives
GB8803301D0 (en) *	1988-02-12	1988-03-09	Erba Carlo Spa	Process for preparation of 4-demethoxy-daunomycinone aglycone of 4-demethoxy-daunorubicin
GB8808475D0 (en) *	1988-04-11	1988-05-11	Erba Carlo Spa	Process for preparing 4-demethoxydauno-mycinone
GB8818167D0 (en) *	1988-07-29	1988-09-01	Erba Carlo Spa	Novel 4-substituted anthracyclinones & process for their preparation
JP2563080B2 (ja) *	1992-03-02	1996-12-11	フアイザー・インコーポレイテツド	マクロライドの糖誘導体
AU2003299378A1 (en) *	2002-10-11	2004-05-04	Board Of Regents, The University Of Texas System	Method and compounds for inhibiting hec1 activity for the treatment of proliferative diseases
EP1845974A1 (fr)	2005-01-21	2007-10-24	Astex Therapeutics Limited	Composes pharmaceutiques
US8916552B2 (en)	2006-10-12	2014-12-23	Astex Therapeutics Limited	Pharmaceutical combinations
US8883790B2 (en)	2006-10-12	2014-11-11	Astex Therapeutics Limited	Pharmaceutical combinations
US8173621B2 (en)	2008-06-11	2012-05-08	Gilead Pharmasset Llc	Nucleoside cyclicphosphates
CL2009002206A1 (es)	2008-12-23	2011-08-26	Gilead Pharmasset Llc	Compuestos derivados de pirrolo -(2-3-d]-pirimidin-7(6h)-tetrahidrofuran-2-il fosfonamidato, composicion farmaceutica; y su uso en el tratamiento de enfermedades virales.
AR074897A1 (es) *	2008-12-23	2011-02-23	Pharmasset Inc	Fosforamidatos de nucleosidos
MX2011006890A (es) *	2008-12-23	2011-07-20	Pharmasset Inc	Analogos de nucleosidos.
KR101806323B1 (ko)	2009-11-13	2017-12-07	다이이치 산쿄 유럽 게엠베하	Ｈｅｒ-３ 관련 질병을 치료하거나 예방하기 위한 물질 및 방법
AP2012006535A0 (en)	2010-03-31	2012-10-31	Gilead Pharmasset Llc	Stereoselective synthesis of phosphorous containing actives
AU2011286407A1 (en)	2010-08-06	2013-02-21	Amgen	Use of HER3 binding agents in prostate treatment
DE102011113652A1 (de) *	2011-09-19	2013-03-21	Heraeus Precious Metals Gmbh & Co. Kg	Kristallisierung von Idarubicinhydrochlorid
DK2750683T4 (da)	2011-10-03	2021-04-12	Croda Int Plc	Nanopartikler, fremgangsmåde til fremstilling og anvendelse deraf som bærer for amfipatiske eller hydrofobe molekyler inden for medicin, herunder cancerbehandling, og i fødevarerelaterede forbindelser
WO2014163558A1 (fr)	2013-04-01	2014-10-09	Moreinx Ab	Nanoparticules, constituées de stérol et de saponine de quillaja saponaria molina, leur procédé de préparation et leur utilisation comme support pour des molécules amphipathiques ou hydrophobes dans le domaine médical, notamment pour le traitement du cancer, et composés alimentaires
EP3669890A1 (fr)	2018-12-18	2020-06-24	Croda International PLC	Nanoparticules filamenteuses ayant un effet d'adjuvant de vaccin

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3427300A (en) *	1965-11-12	1969-02-11	Merck & Co Inc	Anti-inflammatory steroid 2'-acetamido-2'-deoxy-glucoside compounds
US3803124A (en) *	1968-04-12	1974-04-09	Farmaceutici It Soc	Process for the preparation of adriamycin and adriamycinone and adriamycin derivatives
US3686163A (en) *	1968-05-14	1972-08-22	Farmaceutici Italia	Dihydrodaunomycin antibiotic and derivatives thereof

1974
- 1974-06-12 GB GB2608374A patent/GB1467383A/en not_active Expired
1975
- 1975-05-22 US US05/579,901 patent/US4046878A/en not_active Expired - Lifetime
- 1975-06-06 NL NLAANVRAGE7506745,A patent/NL173272C/xx not_active IP Right Cessation
- 1975-06-09 DK DK256875A patent/DK147304C/da not_active IP Right Cessation
- 1975-06-09 FR FR7517881A patent/FR2274629A1/fr active Granted
- 1975-06-09 AT AT437375A patent/AT337363B/de not_active IP Right Cessation
- 1975-06-09 DE DE19752525633 patent/DE2525633A1/de active Granted
- 1975-06-09 DE DE1993175027 patent/DE19375027I2/de active Active
- 1975-06-09 SE SE7506589A patent/SE423633B/xx not_active IP Right Cessation
- 1975-06-10 ZA ZA00753722A patent/ZA753722B/xx unknown
- 1975-06-10 JP JP50069250A patent/JPS5840557B2/ja not_active Expired
- 1975-06-10 SU SU752141338A patent/SU645588A3/ru active
- 1975-06-11 BE BE157205A patent/BE830090A/fr not_active IP Right Cessation
- 1975-06-11 CH CH756375A patent/CH611317A5/xx not_active IP Right Cessation
- 1975-06-11 ES ES438431A patent/ES438431A1/es not_active Expired
1982
- 1982-01-14 HK HK9/82A patent/HK982A/xx unknown
1988
- 1988-12-22 MY MYPI88001506A patent/MY103666A/en unknown
1993
- 1993-11-11 BG BG098211A patent/BG61059B2/bg unknown

Also Published As

Publication number	Publication date
SE7506589L (sv)	1975-12-15
NL173272B (nl)	1983-08-01
DE2525633A1 (de)	1976-01-02
NL7506745A (nl)	1975-12-16
DE2525633B2 (fr)	1979-03-01
MY103666A (en)	1993-08-28
BE830090A (fr)	1975-12-11
FR2274629A1 (fr)	1976-01-09
DE19375027I2 (de)	2002-06-13
JPS5840557B2 (ja)	1983-09-06
DK147304B (da)	1984-06-12
ATA437375A (de)	1976-10-15
SE423633B (sv)	1982-05-17
NL173272C (nl)	1984-01-02
AT337363B (de)	1977-06-27
AU8197975A (en)	1976-12-16
BG61059B2 (bg)	1996-09-30
FR2274629B1 (fr)	1980-01-11
SU645588A3 (ru)	1979-01-30
DK147304C (da)	1984-12-17
JPS518260A (fr)	1976-01-23
GB1467383A (en)	1977-03-16
ES438431A1 (es)	1977-02-01
US4046878A (en)	1977-09-06
HK982A (en)	1982-01-22
DE2525633C3 (fr)	1979-10-18
CH611317A5 (fr)	1979-05-31
DK256875A (da)	1975-12-13

Publication	Publication Date	Title
ZA752880B (en)	1976-04-28	Process for the preparation of teralkyl ethers
HK982A (en)	1982-01-22	Daunomycin analogues
GB1536407A (en)	1978-12-20	Process for the preparation of bis-indolic compounds
ZA756932B (en)	1976-10-27	Method for the preparation of ethers
ZA75893B (en)	1976-01-28	Process for the preparation of carbodiimide-isocyanurate foams
ZA757118B (en)	1976-10-27	Process for the preparation of addition agents
IL47728A (en)	1979-01-31	Process for the preparation of moenomycin
IL48062A0 (en)	1975-11-25	Process for the preparation of metasubstituted halogenophenols
CH613683A5 (en)	1979-10-15	Process for the preparation of secoprostaglandins
CH614194A5 (en)	1979-11-15	Process for the preparation of 5-aroyl- and 5-thenoyl-pyrrole compounds
GB1523797A (en)	1978-09-06	Process for the preparation for the preparation of methanol
CH612908A5 (en)	1979-08-31	Process for the preparation of novel basic ethers
GB1519826A (en)	1978-08-02	Process for the preparation of 11 - hydroxy - 18 - alkylestrane compounds
IL47849A0 (en)	1975-10-15	Process for the preparation of poly-(-n-alkyliminoalanes)
CH612932A5 (en)	1979-08-31	Process for the preparation of alkylsulphonylphenoxy-propanolamines
ZA75976B (en)	1976-01-28	Process for the preparation of cis-vincamine
CH611273A5 (en)	1979-05-31	Process for the preparation of novel 3-oxocyclohex-1-en-1-yl- ureas
AU490640B2 (en)	1976-05-13	Process for the preparation of poly-n-alkyliminoalanes
EG11656A (en)	1977-11-30	Process for the preparation of propanolamin derivatives
ZA753469B (en)	1976-05-26	Process for the preparation of alpha-diol-alpha-dioxo compounds
CH613206A5 (en)	1979-09-14	Process for the preparation of 1-aminomethyl-6-phenyltriazolobenzodiazepine compounds
CH611302A5 (en)	1979-05-31	Process for the preparation of 7-amino-delta3-cephem derivatives
IL47243A0 (en)	1975-07-28	Process for the preparation of 4-hydroxypyrimidines
IL48633A0 (en)	1976-02-29	Process for the preparation of trichlorothiazole
CH613693A5 (en)	1979-10-15	Process for the preparation of trisaminopyridines