ZA792064B - Vitamin b-12 derivative suitable for radiolabeling - Google Patents

Vitamin b-12 derivative suitable for radiolabeling

Info

Publication number
ZA792064B
ZA792064B ZA792064A ZA792064A ZA792064B ZA 792064 B ZA792064 B ZA 792064B ZA 792064 A ZA792064 A ZA 792064A ZA 792064 A ZA792064 A ZA 792064A ZA 792064 B ZA792064 B ZA 792064B
Authority
ZA
South Africa
Prior art keywords
vitamin
radiolabeling
derivative suitable
derivative
radioassays
Prior art date
Application number
ZA792064A
Other languages
English (en)
Inventor
F Weisenborn
Ravi Kannadikovilakom Varma
Kannadikovilakom Varma Ravi
B Vogt
J Bernstein
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of ZA792064B publication Critical patent/ZA792064B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H23/00—Compounds containing boron, silicon or a metal, e.g. chelates or vitamin B12
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/82—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving vitamins or their receptors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Saccharide Compounds (AREA)
ZA792064A 1978-05-30 1979-04-30 Vitamin b-12 derivative suitable for radiolabeling ZA792064B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/910,568 US4209614A (en) 1978-05-30 1978-05-30 Vitamin B12 derivative suitable for radiolabeling

Publications (1)

Publication Number Publication Date
ZA792064B true ZA792064B (en) 1980-05-28

Family

ID=25428998

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA792064A ZA792064B (en) 1978-05-30 1979-04-30 Vitamin b-12 derivative suitable for radiolabeling

Country Status (9)

Country Link
US (1) US4209614A (de)
EP (1) EP0005834B1 (de)
JP (1) JPS54157600A (de)
AT (1) ATE295T1 (de)
AU (1) AU4649179A (de)
CA (1) CA1109464A (de)
DE (1) DE2960982D1 (de)
IL (1) IL57385A0 (de)
ZA (1) ZA792064B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2437398A1 (fr) * 1978-06-20 1980-04-25 Commissariat Energie Atomique Compose iode utilisable comme traceur en radio-immunologie
US4355018A (en) * 1980-05-21 1982-10-19 Hoffmann-La Roche Inc. Assay for vitamin B12
CA1180273A (en) * 1981-06-22 1985-01-02 Technicon Instruments Corporation Assay of vitamin b in12 xx
US4465776A (en) * 1982-09-27 1984-08-14 Research Corporation Monoclonal antibodies to vitamin B6 and immunoassay method
NZ217821A (en) * 1985-10-10 1989-07-27 Biotech Australia Pty Ltd Oral delivery system; complex of active agent and vitamin b12 or analogue thereof
US5807832A (en) * 1987-06-09 1998-09-15 Biotech Australia Pty Limited Oral delivery of biologically active substances bound to vitamin B12
CA2084194C (en) * 1991-04-02 2003-05-20 Gregory John Russell-Jones Oral delivery systems for microparticles
JPH06336494A (ja) * 1993-05-27 1994-12-06 Nippon Oil Co Ltd 疎水性ビタミンｂ１２誘導体
US5739313A (en) 1995-11-13 1998-04-14 Regents Of The University Of Minnesota Radionuclide labeling of vitamin B12 and coenzymes thereof
AUPP405098A0 (en) * 1998-06-12 1998-07-02 Access Pharmaceuticals Australia Pty Limited Novel methods of preparation of vitamin b12 derivatives suitable for conjugation to pharmaceuticals
US6806363B1 (en) * 1999-04-16 2004-10-19 Mayo Foundation For Medical Education & Research Cobalamin conjugates useful as antitumor agents
US7591995B2 (en) * 1999-10-15 2009-09-22 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
JP2003512338A (ja) * 1999-10-15 2003-04-02 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 造影剤および抗腫瘍薬として有用なコバラミン結合体
WO2001028595A1 (en) 1999-10-15 2001-04-26 Mayo Foundation For Medical Education And Research Cobalamin conjugates useful as imaging and therapeutic agents
CA2427146A1 (en) * 2000-10-25 2002-07-18 Mayo Foundation For Medical Education And Research Transcobalamin binding conjugates useful for treating abnormal cellular proliferation
EP1754712A3 (de) * 2000-10-25 2009-01-14 Mayo Foundation For Medical Education And Research Transcobalamin-bindende Konjugate zur Behandlung abnormaler zellulärer Proliferation
US20030018009A1 (en) * 2001-06-20 2003-01-23 Collins Douglas A. Adenosyl-cobalamin fortified compositions
US20060074034A1 (en) * 2001-09-17 2006-04-06 Collins Douglas A Cobalamin mediated delivery of nucleic acids, analogs and derivatives thereof
JP2005508332A (ja) * 2001-09-28 2005-03-31 メイオウ・フアウンデーシヨン・フオー・メデイカル・エジユケイシヨン・アンド・リサーチ 薬剤を送達するための、輸送タンパク質とコンジュゲートコバラミンとの同時投与
KR100440725B1 (ko) * 2002-06-20 2004-07-15 주식회사 그린진 바이오텍 비생물성 스트레스에 대한 단자엽 식물의 내성을증가시키는 방법
AU2004303528B2 (en) * 2003-12-22 2009-05-28 Paul Scherrer Institut Cobalamine derivatives useful for diagnosis and treatment of abnormal cellular proliferation
US8535750B2 (en) * 2005-05-17 2013-09-17 Cargill, Incorporated Granular lecithins, granular lysolecithins, process for their production and compositions containing them

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR5372M (de) * 1966-02-10 1967-10-16
US3981863A (en) * 1975-02-25 1976-09-21 Micromedic Diagonistics, Inc. Cyanocobalamin derivatives
CA1118409A (en) * 1977-08-12 1982-02-16 Jack Bernstein Steroid derivatives and their use in radioimmunoassays

Also Published As

Publication number Publication date
ATE295T1 (de) 1981-10-15
IL57385A0 (en) 1979-09-30
US4209614A (en) 1980-06-24
AU4649179A (en) 1979-12-06
CA1109464A (en) 1981-09-22
EP0005834B1 (de) 1981-10-14
EP0005834A1 (de) 1979-12-12
JPS54157600A (en) 1979-12-12
DE2960982D1 (en) 1981-12-24

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