ZA823873B - Process for the preparation of apovincaminic acid esters - Google Patents

Process for the preparation of apovincaminic acid esters

Info

Publication number: ZA823873B
Authority: ZA; South Africa
Prior art keywords: preparation; acid esters; apovincaminic acid; apovincaminic; esters
Prior art date: 1981-06-12

Application number

ZA823873A

Other languages

English (en)

Inventor

Csaba Szantay

Lajos Szabo

Gyoergy Kalaus

Janos Kreidl

Laszlo Czibula

Gyoergy Visky

Andras Nemes

Maria Farkas

Original Assignee

Richter Gedeon Vegyeszet

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1981-06-12

Filing date

1982-06-02

Publication date

1983-05-25

1982-06-02 Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet

1983-05-25 Publication of ZA823873B publication Critical patent/ZA823873B/xx

Links

ZFCQLDAGNBFMJQ-QUCCMNQESA-N apovincaminic acid Chemical class C1=CC=C2C(CCN3CCC4)=C5[C@@H]3[C@]4(CC)C=C(C(O)=O)N5C2=C1 ZFCQLDAGNBFMJQ-QUCCMNQESA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Hydrogenated Pyridines (AREA)

ZA823873A 1981-06-12 1982-06-02 Process for the preparation of apovincaminic acid esters ZA823873B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
HU811753A HU186891B (en)	1981-06-12	1981-06-12	Process for producing esters of apovincaminic acid

Publications (1)

Publication Number	Publication Date
ZA823873B true ZA823873B (en)	1983-05-25

Family

ID=10956018

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA823873A ZA823873B (en)	1981-06-12	1982-06-02	Process for the preparation of apovincaminic acid esters

Country Status (24)

Country	Link
US (1)	US4474960A (de)
JP (2)	JPS5843971A (de)
AT (1)	AT382619B (de)
AU (2)	AU551445B2 (de)
BE (1)	BE893492A (de)
CA (1)	CA1258071A (de)
CH (2)	CH656128A5 (de)
DE (1)	DE3222096A1 (de)
DK (1)	DK152651C (de)
ES (3)	ES8400433A1 (de)
FI (1)	FI71142C (de)
FR (2)	FR2507605B1 (de)
GB (2)	GB2102415B (de)
GE (1)	GEP19970819B (de)
GR (1)	GR76494B (de)
HU (1)	HU186891B (de)
IL (1)	IL65922A (de)
IT (1)	IT1200961B (de)
NL (1)	NL192452C (de)
NO (1)	NO821954L (de)
PT (1)	PT75042B (de)
SE (2)	SE450383B (de)
SU (2)	SU1258326A3 (de)
ZA (1)	ZA823873B (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
HU182411B (en) *	1981-11-03	1984-01-30	Richter Gedeon Vegyeszet	Process for preparing eburnamonine derivatives
HU191454B (en) *	1984-10-05	1987-02-27	Richter Gedeon Vegyeszeti Gyar Rt.,Hu	Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU198207B (en) *	1985-04-19	1989-08-28	Richter Gedeon Vegyeszet	Process for production of derivatives of eburnamenin and medical compositions containing them
JPH0438474Y2 (de) *	1986-04-30	1992-09-09
JPS63164190U (de) *	1987-02-18	1988-10-26
BE1004471A3 (fr) *	1989-06-21	1992-12-01	Richter Gedeon Vegyeszet	Nouveaux derives diester d'octahydro-indolo-[2,3-a]-tetrahydropyranyl [2,3-c] quinolizine racemiques et optiquement actifs et procede pour les preparer.
HU214600B (hu) *	1995-12-22	1998-04-28	Richter Gedeon Vegyészeti Gyár Rt.	Transz-apovinkaminsav-észter-származékok, az azokat tartalmazó gyógyszerkészítmények és eljárás ezek előállítására
EP1575916B1 (de)	2001-08-31	2013-05-22	The Rockefeller University	Phosphodiesteraseaktivität und regulation der durch phosphodiesterase-1-b vermittelten signalvermittlung im hirn
SG178279A1 (en)	2009-08-05	2012-03-29	Intra Cellular Therapies Inc	Novel regulatory proteins and inhibitors
US10918628B2 (en)	2016-10-11	2021-02-16	Deutsches Zentrum Für Neurodegenerative Erkrankungen E. V. (Dzne)	Treatment of synucleinopathies

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3770724A (en) *	1970-03-31	1973-11-06	Roussel Uclaf	Process for preparing pentacyclic alkaloids
HU163143B (de) *	1971-05-07	1973-06-28
US4033969A (en) *	1972-06-19	1977-07-05	Agence Nationale De Valorisation De La Recherche (Anvar)	Vincamine derivatives
US4033960A (en) *	1973-07-31	1977-07-05	Bayer Aktiengesellschaft	2-Mercaptoquinoxaline-di-N-oxide products and a method for their preparation
AU499923B2 (en) *	1975-06-27	1979-05-03	Richter Gedeon Vegyeszeti Gyar N	Indoloquinolizine derivatives & their production
FR2389625B1 (de) *	1977-05-06	1980-04-18	Roussel Uclaf
FR2459799A1 (fr) *	1979-06-22	1981-01-16	Synthelabo	Synthese de la ()-vincamine
JPS55100383A (en) *	1979-01-25	1980-07-31	Sumitomo Chem Co Ltd	Preparation of novel nitrogen-containing polycyclic compound
AU532001B2 (en) *	1978-11-20	1983-09-15	Sumitomo Chemical Company, Limited	Polycyclic indole derivatives
HU181495B (en) *	1979-05-31	1983-07-28	Richter Gedeon Vegyeszet	Process for producing hydroxy-imino-eburnane derivatives
HU180927B (en) *	1979-07-13	1983-05-30	Richter Gedeon Vegyeszet	Process for producing 1k-hydroximino-e-homoe-eburane de rivatives
FR2468605A1 (fr) *	1979-10-30	1981-05-08	Richter Gedeon Vegyeszet	Procede de preparation d'ester de l'acide apovincaminique
HU182380B (en) *	1981-09-30	1983-12-28	Richter Gedeon Vegyeszet	Process for producing esters of vincaminic acid

1981
- 1981-06-12 HU HU811753A patent/HU186891B/hu not_active IP Right Cessation
1982
- 1982-05-31 IL IL65922A patent/IL65922A/xx not_active IP Right Cessation
- 1982-06-02 FI FI821963A patent/FI71142C/fi not_active IP Right Cessation
- 1982-06-02 ZA ZA823873A patent/ZA823873B/xx unknown
- 1982-06-08 GR GR68366A patent/GR76494B/el unknown
- 1982-06-09 SE SE8203580A patent/SE450383B/sv not_active IP Right Cessation
- 1982-06-09 PT PT75042A patent/PT75042B/pt not_active IP Right Cessation
- 1982-06-10 FR FR8210103A patent/FR2507605B1/fr not_active Expired
- 1982-06-10 CH CH3597/82A patent/CH656128A5/de not_active IP Right Cessation
- 1982-06-10 CH CH5868/84A patent/CH659474A5/de not_active IP Right Cessation
- 1982-06-11 DK DK262982A patent/DK152651C/da not_active IP Right Cessation
- 1982-06-11 IT IT67752/82A patent/IT1200961B/it active
- 1982-06-11 BE BE0/208331A patent/BE893492A/fr not_active IP Right Cessation
- 1982-06-11 AU AU84798/82A patent/AU551445B2/en not_active Ceased
- 1982-06-11 DE DE19823222096 patent/DE3222096A1/de not_active Withdrawn
- 1982-06-11 SU SU3452054A patent/SU1258326A3/ru active
- 1982-06-11 NO NO821954A patent/NO821954L/no unknown
- 1982-06-11 US US06/387,676 patent/US4474960A/en not_active Expired - Lifetime
- 1982-06-11 NL NL8202396A patent/NL192452C/nl not_active IP Right Cessation
- 1982-06-11 ES ES513016A patent/ES8400433A1/es not_active Expired
- 1982-06-11 GB GB08217030A patent/GB2102415B/en not_active Expired
- 1982-06-11 AT AT0227182A patent/AT382619B/de not_active IP Right Cessation
- 1982-06-12 JP JP57099997A patent/JPS5843971A/ja active Pending
- 1982-12-14 FR FR8220957A patent/FR2515653B1/fr not_active Expired
1983
- 1983-02-22 SU SU833557652A patent/SU1376947A3/ru active
- 1983-06-11 CA CA000405030A patent/CA1258071A/en not_active Expired
- 1983-06-16 ES ES523345A patent/ES8504192A1/es not_active Expired
1984
- 1984-11-30 ES ES538125A patent/ES8604581A1/es not_active Expired
1985
- 1985-01-07 GB GB08500325A patent/GB2151629B/en not_active Expired
1986
- 1986-03-13 AU AU54712/86A patent/AU568790B2/en not_active Ceased
1987
- 1987-01-02 SE SE8700015A patent/SE461654B/sv not_active IP Right Cessation
1991
- 1991-09-26 JP JP3317577A patent/JPH0714932B2/ja not_active Expired - Lifetime
1993
- 1993-07-07 GE GEAP1993974A patent/GEP19970819B/en unknown

Also Published As

Publication number	Publication date
FR2515653A1 (fr)	1983-05-06
IL65922A (en)	1985-07-31
DK152651B (da)	1988-04-05
PT75042B (en)	1984-10-09
GB2151629A (en)	1985-07-24
CA1258071A (en)	1989-08-01
GB2151629B (en)	1986-01-02
FR2515653B1 (fr)	1985-12-06
FI71142B (fi)	1986-08-14
FR2507605A1 (fr)	1982-12-17
NL192452C (nl)	1997-08-04
JPH0714932B2 (ja)	1995-02-22
IL65922A0 (en)	1982-08-31
PT75042A (en)	1982-07-01
BE893492A (fr)	1982-12-13
AT382619B (de)	1987-03-25
SE8700015L (sv)	1987-01-02
AU568790B2 (en)	1988-01-07
SE450383B (sv)	1987-06-22
AU5471286A (en)	1986-07-31
AU551445B2 (en)	1986-05-01
ES523345A0 (es)	1985-04-01
DE3222096A1 (de)	1983-01-05
NL8202396A (nl)	1983-01-03
AU8479882A (en)	1982-12-16
SE8700015D0 (sv)	1987-01-02
GB8500325D0 (en)	1985-02-13
HU186891B (en)	1985-10-28
JPH0517474A (ja)	1993-01-26
GEP19970819B (en)	1997-01-30
GB2102415A (en)	1983-02-02
NO821954L (no)	1982-12-13
ES8504192A1 (es)	1985-04-01
GB2102415B (en)	1986-01-02
DK262982A (da)	1982-12-13
ES513016A0 (es)	1983-10-16
FI821963A0 (fi)	1982-06-02
IT1200961B (it)	1989-01-27
ES8604581A1 (es)	1986-02-01
US4474960A (en)	1984-10-02
ES538125A0 (es)	1986-02-01
SE461654B (sv)	1990-03-12
ATA227182A (de)	1986-08-15
JPS5843971A (ja)	1983-03-14
CH659474A5 (de)	1987-01-30
DK152651C (da)	1988-08-22
SU1376947A3 (ru)	1988-02-23
GR76494B (de)	1984-08-10
ES8400433A1 (es)	1983-10-16
SU1258326A3 (ru)	1986-09-15
FR2507605B1 (fr)	1985-12-13
CH656128A5 (de)	1986-06-13
NL192452B (nl)	1997-04-01
SE8203580L (sv)	1982-12-13
IT8267752A0 (it)	1982-06-11
FI71142C (fi)	1986-11-24

Publication	Publication Date	Title
DE3261722D1 (en)	1985-02-14	Process for the production of glycollic acid esters
DE3060921D1 (en)	1982-11-11	Process for the preparation of formyl-valeric acid esters
DE3277839D1 (en)	1988-01-28	Process for the preparation of (2s)-tetrahydro-2alpha-methyl-6-oxo-4beta-amino-2h-pyran-3alpha-carboxylic acid esters
ZA823873B (en)	1983-05-25	Process for the preparation of apovincaminic acid esters
YU125184A (en)	1985-04-30	Process for obtaining 3-methyl-flavone8-carboxylic acid esters
EG15908A (en)	1990-08-30	Improved process for the preparation of penicillanic acid esters
DE3060926D1 (en)	1982-11-18	Process for the preparation of alcanediol-bis-aminobenzoic acid esters
ZA813537B (en)	1982-06-30	Process for the preparation of diacetone-ketogulonic acid
IL66891A0 (en)	1982-12-31	Process for the preparation of vincaminic acid esters
DE3261033D1 (en)	1984-11-29	Process for the preparation of dialkyl esters of maleic acid
DE3264312D1 (en)	1985-07-25	Process for the preparation of n-formyl-alpha-amino-acid esters
GB2105718B (en)	1986-04-03	Process for the preparation of alkoxyvincaminic acid esters and alkoxyapovincaminic acid esters
DE3563960D1 (en)	1988-09-01	Process for the preparation of esters of hydroxymethylene-alcoxyacetic acid
ZA825511B (en)	1983-07-27	Process for the preparation of-hydroxy-phosphonic acid esters
ZA821903B (en)	1983-01-26	Process for the preparation of penicillanic acid esters
GB2086886B (en)	1984-06-13	Process for the preparation of apovincaminic acid esters
DE3265083D1 (en)	1985-09-05	Process for the preparation of 2,2-dichlorophenylacetic acid esters
GB2092135B (en)	1985-02-06	Process for the preparation of an ester of formic acid
DE3362715D1 (en)	1986-04-30	Process for the preparation of 2-hydroxy-carbazole-1-carboxylic acid
DE3260245D1 (en)	1984-07-19	Process for the preparation of 5-oxohexanoic acid
ZA813397B (en)	1982-06-30	Process for the preparation of diacetoneketogulonic acid
DE3160531D1 (en)	1983-08-04	Process for the preparation of 1-aminoanthraquinone-2-carboxylic acid
DE2961623D1 (en)	1982-02-18	Process for the preparation of esters of butanedicarboxylic acid
GB2121795B (en)	1985-12-24	Process for the preparation of acetic acid
DE3261459D1 (en)	1985-01-17	Process for the preparation of permethrinic-acid menthyl ester