ZA832410B - Olefinic benzimidazoles - Google Patents

Olefinic benzimidazoles

Info

Publication number
ZA832410B
ZA832410B ZA832410A ZA832410A ZA832410B ZA 832410 B ZA832410 B ZA 832410B ZA 832410 A ZA832410 A ZA 832410A ZA 832410 A ZA832410 A ZA 832410A ZA 832410 B ZA832410 B ZA 832410B
Authority
ZA
South Africa
Prior art keywords
benzimidazoles
olefinic
olefinic benzimidazoles
Prior art date
Application number
ZA832410A
Other languages
English (en)
Inventor
Tina Marie Morwick
Charles Johnson Paget Jr
James Howard Wikel
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of ZA832410B publication Critical patent/ZA832410B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D235/30—Nitrogen atoms not forming part of a nitro radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA832410A 1982-04-08 1983-04-05 Olefinic benzimidazoles ZA832410B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/366,760 US4420479A (en) 1982-04-08 1982-04-08 Olefinic benzimidazoles, formulations, and antiviral methods

Publications (1)

Publication Number Publication Date
ZA832410B true ZA832410B (en) 1984-11-28

Family

ID=23444387

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA832410A ZA832410B (en) 1982-04-08 1983-04-05 Olefinic benzimidazoles

Country Status (18)

Country Link
US (1) US4420479A (fr)
EP (1) EP0091795A1 (fr)
KR (1) KR840004409A (fr)
AU (1) AU1322483A (fr)
CA (1) CA1197245A (fr)
DD (1) DD209624A5 (fr)
DK (1) DK152883A (fr)
ES (2) ES521318A0 (fr)
FI (1) FI831191A7 (fr)
GB (1) GB2119789B (fr)
GR (1) GR78168B (fr)
IL (1) IL68299A0 (fr)
NZ (1) NZ203798A (fr)
PH (1) PH18108A (fr)
PL (3) PL247909A1 (fr)
PT (1) PT76499B (fr)
RO (1) RO86319B (fr)
ZA (1) ZA832410B (fr)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69214467T3 (de) * 1991-01-10 2000-09-28 Transcend Therapeutics, Inc. Verwendung von L-2-oxo Thiazolidin-4-carboxylat zur Behandlung von Atemnotsyndrom
US5747459A (en) * 1991-02-04 1998-05-05 Nestec, Ltd. Method for insuring adequate intracellular glutathione in tissue
US5430045A (en) * 1992-04-23 1995-07-04 Free Radical Sciences, Inc. Method of reducing or preventing bone marrow hypoplasia
JP2787539B2 (ja) * 1993-02-26 1998-08-20 松森　　昭 ウイルス性疾患の予防または治療剤
US5447712A (en) * 1993-12-09 1995-09-05 Free Radical Sciences Method of reducing cyclophosphamide induced hemorrhagic cystitis
US5475109A (en) * 1994-10-17 1995-12-12 Merck & Co., Inc. Dioxobutanoic acid derivatives as inhibitors of influenza endonuclease
US5693661A (en) * 1995-06-07 1997-12-02 Eli Lilly And Company Anti-viral compounds
US5545653A (en) * 1995-06-07 1996-08-13 Eli Lilly And Company Anti-viral compounds
US5891874A (en) * 1996-06-05 1999-04-06 Eli Lilly And Company Anti-viral compound
JP2000511899A (ja) * 1996-06-05 2000-09-12 イーライ・リリー・アンド・カンパニー 抗―ウイルス性化合物群
US5821242A (en) * 1996-06-06 1998-10-13 Eli Lilly And Company Anti-viral compounds
JP4214537B2 (ja) 1996-08-12 2009-01-28 セルジーン コーポレーション 新規な免疫治療薬とこの薬物を使用してサイトカインレベルを抵減する方法
AU6031898A (en) * 1997-01-22 1998-08-07 Eli Lilly And Company Anti-viral compounds
AU7715198A (en) * 1997-06-04 1998-12-21 Eli Lilly And Company Anti-viral compounds
US7470723B2 (en) 2003-03-05 2008-12-30 Celgene Corporation Diphenylethylene compounds and uses thereof
BRPI0408005A (pt) 2003-03-05 2006-02-14 Celgene Corp composto, composição farmacêutica, métodos para inibir angiogênese, atividade de pde4 em uma célula e proliferação de célula de cáncer, para inibir ou reduzir polimerização de tubulina ou estabilidade de tubulina em uma célula, para tratar ou melhorar um distúrbio inflamatório, um cáncer e um distúrbio do sistema nervoso central e para visar, bloquear ou destruir a função de vasculatura de tumor e o endotélio de vasos de tumor
EP1794139A2 (fr) 2004-09-03 2007-06-13 Celgene Corporation Composes heterocycliques substitues et leurs utilisations
CN108997158B (zh) * 2018-07-16 2020-12-15 青岛科技大学 一种实现二取代酰胺与二苯基甲酮偶联的方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4018790A (en) * 1975-05-08 1977-04-19 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles
PT65486B (en) * 1975-08-28 1978-03-24 Lilly Co Eli Process for the preparation of carbonil-substituted 1-sulfonylbenzimidazoles
US4174454A (en) * 1975-08-28 1979-11-13 Eli Lilly And Company Alkylidenylmethyl-substituted 1-sulfonylbenzimidazoles
CA1076582A (fr) * 1975-10-28 1980-04-29 Charles J. Paget Thiazolinyle ou thiazinyle cetobenzimidazoles antiviraux
US4008243A (en) * 1975-11-19 1977-02-15 Eli Lilly And Company Antiviral thiazolinyl or thiazinyl benzimidazole esters
US4118573A (en) * 1975-11-24 1978-10-03 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles
GR66420B (fr) * 1976-12-15 1981-03-20 Lilly Co Eli
US4230868A (en) * 1979-04-17 1980-10-28 Eli Lilly And Company α-Alkyl-α-hydroxybenzyl-substituted 1-sulfonylbenzimidazoles
US4316021A (en) * 1979-08-13 1982-02-16 Eli Lilly And Company Substituted 1-sulfonylbenzimidazoles

Also Published As

Publication number Publication date
FI831191L (fi) 1983-10-09
DD209624A5 (de) 1984-05-16
RO86319A (fr) 1985-03-15
FI831191A0 (fi) 1983-04-08
RO86319B (ro) 1985-03-31
PL241385A1 (en) 1984-09-24
EP0091795A1 (fr) 1983-10-19
GB2119789B (en) 1985-08-29
ES8505966A1 (es) 1985-06-01
DK152883A (da) 1983-10-09
US4420479A (en) 1983-12-13
PL247909A1 (en) 1984-12-17
DK152883D0 (da) 1983-04-06
CA1197245A (fr) 1985-11-26
ES8502097A1 (es) 1984-12-16
PT76499A (en) 1983-05-01
KR840004409A (ko) 1984-10-15
GB2119789A (en) 1983-11-23
PL247908A1 (en) 1985-01-16
AU1322483A (en) 1983-10-13
ES534218A0 (es) 1985-06-01
ES521318A0 (es) 1984-12-16
IL68299A0 (en) 1983-07-31
FI831191A7 (fi) 1983-10-09
GR78168B (fr) 1984-09-26
NZ203798A (en) 1985-07-12
PT76499B (en) 1986-03-18
PH18108A (en) 1985-03-22

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