ZA836330B - 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation - Google Patents

1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation

Info

Publication number
ZA836330B
ZA836330B ZA836330A ZA836330A ZA836330B ZA 836330 B ZA836330 B ZA 836330B ZA 836330 A ZA836330 A ZA 836330A ZA 836330 A ZA836330 A ZA 836330A ZA 836330 B ZA836330 B ZA 836330B
Authority
ZA
South Africa
Prior art keywords
aminomethyl
tetrahydro
preparation
methods
phenyl
Prior art date
Application number
ZA836330A
Other languages
English (en)
Inventor
Ronald C Griffith
Original Assignee
Pennwalt Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pennwalt Corp filed Critical Pennwalt Corp
Publication of ZA836330B publication Critical patent/ZA836330B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA836330A 1982-09-27 1983-08-26 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation ZA836330B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/423,958 US4518779A (en) 1982-09-27 1982-09-27 1,2,3,4-Tetrahydro-1-aminomethyl-4-phenyl isoquinolines

Publications (1)

Publication Number Publication Date
ZA836330B true ZA836330B (en) 1984-07-25

Family

ID=23680888

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA836330A ZA836330B (en) 1982-09-27 1983-08-26 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation

Country Status (17)

Country Link
US (1) US4518779A (da)
EP (1) EP0104604B1 (da)
JP (1) JPS5978164A (da)
KR (1) KR840006209A (da)
AT (1) ATE34386T1 (da)
AU (1) AU564040B2 (da)
BR (1) BR8305272A (da)
CA (1) CA1228360A (da)
DE (1) DE3376650D1 (da)
DK (1) DK438883A (da)
FI (1) FI833443L (da)
IE (1) IE55970B1 (da)
IL (1) IL69624A (da)
NO (1) NO833465L (da)
NZ (1) NZ205422A (da)
PH (1) PH19712A (da)
ZA (1) ZA836330B (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE97893T1 (de) * 1988-02-19 1993-12-15 Smithkline Beecham Farma 1,2,3,4-tetrahydroisoquinoline, verfharen zu ihrer herstellung und ihre verwendung als kappa- rezeptor agonisten.
GB8827479D0 (en) * 1988-11-24 1988-12-29 Zambeletti Spa L Novel compounds
SG10202100724UA (en) * 2016-07-29 2021-03-30 Sunovion Pharmaceuticals Inc Compounds and compositions and uses thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3420818A (en) * 1964-08-07 1969-01-07 Sandoz Ag Tetrahydroisoquinolines
US3435038A (en) * 1965-06-01 1969-03-25 Sandoz Ag 5,6,7,9,10,14b-hexahydroisoquinolo (2,1-d) benzo (1,4) diazepines
US3666763A (en) * 1970-01-06 1972-05-30 Hoffmann La Roche 4-phenyl isoquinolines and process for preparing same
DK496275A (da) * 1974-11-06 1976-05-07 Fujisawa Pharmaceutical Co Fremgangsmade til fremstilling af 1,2,3,4-tetrahydroisoquinoliner
DE2811361A1 (de) * 1978-03-16 1979-09-27 Hoechst Ag Neue isochinolinaldehyde und verfahren zu ihrer herstellung
JPS5587771A (en) * 1978-12-27 1980-07-02 Teikoku Hormone Mfg Co Ltd 1-phenylisoquinoline derivative
DE3011156A1 (de) * 1980-03-22 1981-10-01 Merck Patent Gmbh, 6100 Darmstadt Verfahren zur herstellung von isochinolinderivaten
US4340600A (en) * 1980-05-22 1982-07-20 Smithkline Corporation Renal dilating methods and compositions using 4-(3,4-dihydroxyphenyl)-1,2,3,4-tetrahydroisoquinolines

Also Published As

Publication number Publication date
IE832205L (en) 1984-03-27
IL69624A0 (en) 1983-12-30
DK438883D0 (da) 1983-09-26
CA1228360A (en) 1987-10-20
US4518779A (en) 1985-05-21
NZ205422A (en) 1986-07-11
AU564040B2 (en) 1987-07-30
IL69624A (en) 1987-01-30
FI833443A7 (fi) 1984-03-28
KR840006209A (ko) 1984-11-22
DE3376650D1 (en) 1988-06-23
BR8305272A (pt) 1984-05-02
ATE34386T1 (de) 1988-06-15
EP0104604B1 (en) 1988-05-18
PH19712A (en) 1986-06-17
NO833465L (no) 1984-03-28
DK438883A (da) 1984-03-28
IE55970B1 (en) 1991-03-13
AU1911283A (en) 1984-04-05
JPS5978164A (ja) 1984-05-04
EP0104604A1 (en) 1984-04-04
FI833443A0 (fi) 1983-09-26
FI833443L (fi) 1984-03-28

Similar Documents

Publication Publication Date Title
ZA868119B (en) Process for the preparation of(2,2)-paracyclophane
GR3005053T3 (da)
JPS557287A (en) Aryloxypropanol amine
DE3569375D1 (en) Process for the preparation of 1,2-benzisothiazolones
DE3269600D1 (en) Substituted phenoxypropionates, process for their preparation and their use as herbicides
DE3160009D1 (en) 3,3-dimethyl-1-phenoxy-2-butanols, process for their preparation and their use as intermediates
DE3161047D1 (en) Process for the preparation of hexafluoraceton, and the use of the solution obtained by this process
DE3376650D1 (en) 1,2,3,4-tetrahydro-1-aminomethyl-4-phenyl isoquinolines and methods of preparation
RO87709A (ro) Procedeu pentru prepararea unor 1,1-alcandioli-carboxilati
EP0113880A3 (en) Derivatives from 2-azabicyclo(2.2.1)heptane, process for their preparation, agents containing them and their use, and 2-azabicyclo(2.2.1)heptane derivatives as intermediates, and process for their preparation
IL77661A (en) Process for the preparation of 4,4-azetidinones,and novel intermediates thereof
FI865220A7 (fi) Menetelmä sulfinyyli- ja sulfonyylisubstituoitujen 3-bentsatsepiinien valmistamiseksi.
DE3378823D1 (en) Process for the preparation of 2,4,5,6-tetrachloropyrimidine
PT83799A (en) Process for the preparation of novel 2,2:-bi-1h-imidazoles
EP0226558A3 (en) Chemical intermediates and methods for their preparation
IL76243A0 (en) Process and intermediates for the preparation of aromatic-1,4-oxazepinones and-thiones
PT85023A (en) Process for the preparation of substituted 2-phenylacetil-1,3,5-cyclohexanetriones and of intermediates
GR861895B (en) Process for the preparation of 3,7-disubstituted-3-cephem compounds
DE3163774D1 (en) Process for the preparation of 5-amino-2,4 dimethylacetanilide
PT83196A (en) Process for the preparation of thiadiazolyloxyacetamides used as herbicides
EP0198795A3 (en) Process for the preparation of 1,4-diaminoanthraquinones
EP0195738A3 (en) Process for the preparation of n,n -diisopropyl-2-benzothiazyl-sulfenamide
DE3364377D1 (en) Dialkoxymethyl-butyrolactone, process and intermediates for their preparation and their use
PT83637A (en) Process for the preparation of antidepressant 5-heterocyclic-2,4-dialkyl-3h-1,2,4-triazole-3-thiones
ZA813601B (en) Process for the preparation of 1-carbamoyl-3-(3,5-dichlororphenyl)-hydantoins and an intermediate therefor