ZA855082B - Derivatives of oxaazaphosphorine,their preparation and pharmaceutical compositions containing them - Google Patents

Derivatives of oxaazaphosphorine,their preparation and pharmaceutical compositions containing them

Info

Publication number: ZA855082B
Authority: ZA; South Africa
Prior art keywords: oxaazaphosphorine; derivatives; preparation; pharmaceutical compositions; compositions containing
Prior art date: 1984-07-06

Application number

ZA855082A

Other languages

English (en)

Inventor

Gilbert Lavielle

Claude Cudennec

Original Assignee

Adir

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1984-07-06

Filing date

1985-07-05

Publication date

1986-02-26

1985-07-05 Application filed by Adir filed Critical Adir

1986-02-26 Publication of ZA855082B publication Critical patent/ZA855082B/xx

Links

239000008194 pharmaceutical composition Substances 0.000 title 1
125000003545 alkoxy group Chemical group 0.000 abstract 2
125000000217 alkyl group Chemical group 0.000 abstract 2
229910052736 halogen Inorganic materials 0.000 abstract 2
125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 2
ZZVDXRCAGGQFAK-UHFFFAOYSA-N 2h-oxazaphosphinine Chemical class N1OC=CC=P1 ZZVDXRCAGGQFAK-UHFFFAOYSA-N 0.000 abstract 1
206010028980 Neoplasm Diseases 0.000 abstract 1
230000000118 anti-neoplastic effect Effects 0.000 abstract 1
150000001875 compounds Chemical class 0.000 abstract 1
125000000753 cycloalkyl group Chemical group 0.000 abstract 1
125000005843 halogen group Chemical group 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
125000002757 morpholinyl group Chemical group 0.000 abstract 1
125000000951 phenoxy group Chemical group [H]C1=C([H])C([H])=C(O*)C([H])=C1[H] 0.000 abstract 1
125000003884 phenylalkyl group Chemical group 0.000 abstract 1
125000004193 piperazinyl group Chemical group 0.000 abstract 1
125000005936 piperidyl group Chemical group 0.000 abstract 1
125000000719 pyrrolidinyl group Chemical group 0.000 abstract 1
238000002560 therapeutic procedure Methods 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6581—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms
- C07F9/6584—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and nitrogen atoms with or without oxygen or sulfur atoms, as ring hetero atoms having one phosphorus atom as ring hetero atom
- C07F9/65842—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring
- C07F9/65846—Cyclic amide derivatives of acids of phosphorus, in which one nitrogen atom belongs to the ring the phosphorus atom being part of a six-membered ring which may be condensed with another ring system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Biochemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Compounds Of Unknown Constitution (AREA)
Plural Heterocyclic Compounds (AREA)
Cephalosporin Compounds (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

ZA855082A 1984-07-06 1985-07-05 Derivatives of oxaazaphosphorine,their preparation and pharmaceutical compositions containing them ZA855082B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
FR8410731A FR2567129B1 (fr)	1984-07-06	1984-07-06	Nouveaux derives de l'oxaazaphosphorine, leur procede de preparation et les compositions pharmaceutiques les renfermant

Publications (1)

Publication Number	Publication Date
ZA855082B true ZA855082B (en)	1986-02-26

Family

ID=9305857

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA855082A ZA855082B (en)	1984-07-06	1985-07-05	Derivatives of oxaazaphosphorine,their preparation and pharmaceutical compositions containing them

Country Status (15)

Country	Link
US (1)	US4605647A (de)
EP (1)	EP0172059B1 (de)
JP (1)	JPS6144894A (de)
AT (1)	ATE33658T1 (de)
AU (1)	AU571414B2 (de)
CA (1)	CA1249818A (de)
DE (1)	DE3562252D1 (de)
ES (1)	ES8608530A1 (de)
FR (1)	FR2567129B1 (de)
GR (1)	GR851667B (de)
IE (1)	IE58137B1 (de)
NZ (1)	NZ212663A (de)
OA (1)	OA08056A (de)
PT (1)	PT80781B (de)
ZA (1)	ZA855082B (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5254587A (en) *	1990-09-04	1993-10-19	Burzynski Stanislaw R	Methods for treating AIDS
AU2001270479B2 (en) *	2000-07-18	2005-06-30	Leo Pharma A/S	Matrix metalloproteinase inhibitors
BR0306569A (pt) *	2002-01-18	2004-11-30	Leo Pharma As	Composto, isÈmero de um composto, composição farmacêutica, método para o tratamento ou profilaxia de doenças ou condições que envolvem colapso de tecido, inflamação ou distúrbios proliferativos, e, uso de um composto

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS54157580A (en) *	1978-05-29	1979-12-12	Otsuka Pharmaceut Co Ltd	Optically active oxazaphosphorine derivative
DE3111428A1 (de) *	1981-03-24	1982-10-07	Asta-Werke Ag, Chemische Fabrik, 4800 Bielefeld	Oxazaphosphorin-4-thio-alkansulfonsaeuren und deren neutrale salze, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zubereitungen
JPS5931787A (ja) *	1982-08-13	1984-02-20	Otsuka Pharmaceut Co Ltd	１，３，２−オキサアザホスホリナン−２−オキシド誘導体
JPS5929696A (ja) *	1982-08-13	1984-02-16	Otsuka Pharmaceut Co Ltd	２−〔（ｎ−ニトロソ）−２−ハロゲノエチルアミノ〕−１，３，２−オキサアザホスホリナン−２−オキシド誘導体
FR2536075B1 (fr) *	1982-11-17	1985-07-05	Adir	Nouveaux derives de la nitrosouree, leur procede de preparation et les compositions pharmaceutiques les renfermant

1984
- 1984-07-06 FR FR8410731A patent/FR2567129B1/fr not_active Expired
1985
- 1985-05-31 CA CA000482990A patent/CA1249818A/fr not_active Expired
- 1985-07-04 DE DE8585401359T patent/DE3562252D1/de not_active Expired
- 1985-07-04 AT AT85401359T patent/ATE33658T1/de not_active IP Right Cessation
- 1985-07-04 EP EP85401359A patent/EP0172059B1/de not_active Expired
- 1985-07-05 ZA ZA855082A patent/ZA855082B/xx unknown
- 1985-07-05 JP JP60148144A patent/JPS6144894A/ja active Granted
- 1985-07-05 AU AU44641/85A patent/AU571414B2/en not_active Ceased
- 1985-07-05 US US06/752,365 patent/US4605647A/en not_active Expired - Fee Related
- 1985-07-05 NZ NZ212663A patent/NZ212663A/xx unknown
- 1985-07-05 OA OA58631A patent/OA08056A/xx unknown
- 1985-07-05 ES ES544927A patent/ES8608530A1/es not_active Expired
- 1985-07-05 PT PT80781A patent/PT80781B/pt not_active IP Right Cessation
- 1985-07-05 GR GR851667A patent/GR851667B/el unknown
- 1985-07-05 IE IE169885A patent/IE58137B1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
ES8608530A1 (es)	1986-07-16
FR2567129A1 (fr)	1986-01-10
EP0172059B1 (de)	1988-04-20
ES544927A0 (es)	1986-07-16
ATE33658T1 (de)	1988-05-15
EP0172059A1 (de)	1986-02-19
PT80781B (pt)	1987-10-20
OA08056A (fr)	1987-03-31
IE58137B1 (en)	1994-07-14
CA1249818A (fr)	1989-02-07
AU4464185A (en)	1986-01-09
DE3562252D1 (en)	1988-05-26
IE851698L (en)	1986-01-06
FR2567129B1 (fr)	1986-12-05
JPH0250120B2 (de)	1990-11-01
AU571414B2 (en)	1988-04-14
US4605647A (en)	1986-08-12
NZ212663A (en)	1988-06-30
GR851667B (de)	1985-11-26
JPS6144894A (ja)	1986-03-04
PT80781A (fr)	1985-08-01

Similar Documents

Publication	Publication Date	Title
DE3366141D1 (en)	1986-10-16	1-phenylisoquinoline derivatives, process for their preparation, pharmaceutical compositions containing these compounds and their use
EG15121A (en)	1986-09-30	Process for preparing of cephalosporin derivatives
PH16119A (en)	1983-06-30	New hydroxypropyl-triazole compound,their composition and medicinal use
AU580822B2 (en)	1989-02-02	New pyrrolobenzimidazoles, processes for the preparation thereof and pharmaceutical compositions containing them
AU584235B2 (en)	1989-05-18	New tricyclic compounds, processes for the preparation thereof and pharmaceutical compositions containing them
DE3562252D1 (en)	1988-05-26	Derivatives of oxaazaphosphorine, process for their preparation and pharmaceutical compositions containing them
IL61989A0 (en)	1981-02-27	Phenyl piperazine derivatives of 1,3,4-oxadiazolylphenols,their preparation and pharmaceutical compositions containing them
DE3371515D1 (en)	1987-06-19	Cycloalkyl derivatives of benzisoselenazolones, process for their preparation and pharmaceutical compositions containing them
DE3365900D1 (en)	1986-10-09	Nitrosourea derivatives, process for their preparation and pharmaceutical compositions containing them
IL60323A0 (en)	1980-09-16	Pseudotrisaccharide compounds,their preparation and their medicinal use
ES8604118A1 (es)	1986-01-16	Procedimiento de preparacion de nuevos derivados a-etilben- zol con un grupo n-carbamiloxi sustituido
IL65493A0 (en)	1982-07-30	Phenethanolamine derivatives,their preparation and pharmaceutical compositions containing them
ZA796789B (en)	1980-12-31	Novel 3,4-diaza-bicyclo (4.1.0) hept-2-en-5-ones, their preparation, and therapeutic agents containing these compounds
SE7909514L (sv)	1981-05-17	Nya halofenyl-pyridyl-allylaminderivat
EP0112511A3 (en)	1985-11-13	New compounds, pharmaceutical preparations containing same and process for their preparation
ZA874470B (en)	1989-02-22	New tetrahydrobenzothiazoles,and the preparation and use thereof
IL65756A (en)	1985-04-30	N-substituted 2-methylnaphthylamides,their preparation and their use as fungicides
ES438537A1 (es)	1977-01-16	Procedimiento para la preparacion de nuevos compuestos de 1-(2', 4', 6',-trihidroxifenil)-propandiona-(1, 2) sustitui-dos en la posicion 3.