ZA861013B - Novel disaccharide and trisaccharide derivatives of the"lipid a"type - Google Patents

Novel disaccharide and trisaccharide derivatives of the"lipid a"type

Info

Publication number
ZA861013B
ZA861013B ZA861013A ZA861013A ZA861013B ZA 861013 B ZA861013 B ZA 861013B ZA 861013 A ZA861013 A ZA 861013A ZA 861013 A ZA861013 A ZA 861013A ZA 861013 B ZA861013 B ZA 861013B
Authority
ZA
South Africa
Prior art keywords
lipid
type
novel disaccharide
trisaccharide derivatives
trisaccharide
Prior art date
Application number
ZA861013A
Other languages
English (en)
Inventor
Constant Adriaan Anton Boeckel
Tom Beetz
Original Assignee
Akzo Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nv filed Critical Akzo Nv
Publication of ZA861013B publication Critical patent/ZA861013B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/04—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals attached to acyclic carbon atoms
    • C07H13/06—Fatty acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA861013A 1985-02-22 1986-02-11 Novel disaccharide and trisaccharide derivatives of the"lipid a"type ZA861013B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8500499 1985-02-22

Publications (1)

Publication Number Publication Date
ZA861013B true ZA861013B (en) 1986-09-24

Family

ID=19845570

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA861013A ZA861013B (en) 1985-02-22 1986-02-11 Novel disaccharide and trisaccharide derivatives of the"lipid a"type

Country Status (13)

Country Link
US (1) US4719202A (da)
EP (1) EP0192296B1 (da)
JP (1) JPS61246195A (da)
KR (1) KR860006479A (da)
AU (1) AU583093B2 (da)
CA (1) CA1259308A (da)
DE (1) DE3661538D1 (da)
DK (1) DK83386A (da)
ES (1) ES8707967A1 (da)
FI (1) FI860747A7 (da)
GR (1) GR860379B (da)
PT (1) PT82067B (da)
ZA (1) ZA861013B (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU199494B (en) * 1985-06-28 1990-02-28 Sandoz Ag Process for producing new saccharides and pharmaceutical compositions comprising same
DE3604681A1 (de) * 1986-02-14 1987-08-20 Bayer Ag Neue n-glycosylamidderivate, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
US4929604A (en) * 1986-05-28 1990-05-29 Board Of Regents, The University Of Texas System Lipopolysaccharides of reduced toxicity and the production thereof
EP0333243A3 (en) * 1988-03-10 1989-09-27 Akzo N.V. Sulphated k5 antigen and sulphated k5 antigen fragments
IT1229514B (it) * 1989-01-30 1991-09-03 Farmhispania S A A Montme Glicoconiugati anfifilici sintetici per impiego neurologico.
JPH0655749B2 (ja) * 1989-09-20 1994-07-27 日本たばこ産業株式会社 リピッドａ単糖類縁体
EP0457910A4 (en) * 1989-11-09 1992-05-13 Japan Tobacco Inc. Novel glucosamine derivative and liposome containing the same as membrane component
KR940000166B1 (ko) * 1989-11-09 1994-01-08 니혼다바고 상교오 가부시기가이샤 신규 글루코사민 유도체 및 이것을 막 구성성분으로서 함유한 리포솜
CA2059272A1 (en) * 1990-04-12 1991-10-13 Akira Hasegawa 4,6-0-hydroxyphosphoryl-glucosamine derivatives
US5158941A (en) * 1990-06-08 1992-10-27 E. I. Du Pont De Nemours And Company Lipid A analog as stimulant for production of interleukin-1 in human monocytes and tumor cell growth inhibitor
PL181241B1 (pl) * 1993-11-17 2001-06-29 Deutsche Om Arzneimittel Gmbh Disacharydy beta(1 6)glukozoaminowe, sposób wytwarzania disacharydu beta(1 6) glukozoaminowego, zawierająca je kompozycja farmaceutyczna i środek immunomodulujący i/lub przeciwnowotworowy oraz szczepionka
US5648343A (en) * 1994-02-28 1997-07-15 The University Of Georgia Research Foundation Method for treating LPS-mediated disorders
FR2751876B1 (fr) * 1996-07-31 1998-12-31 Roc Sa Utilisation d'un oligosaccharide comme immunomodulateur, composition dermato-cosmetique et methode de traitement cosmetique
EP1104767A1 (en) 1999-11-30 2001-06-06 Stichting Dienst Landbouwkundig Onderzoek Mono- and disaccharide derivatives containing both fatty acid ester and sulfate ester groups
FR2804684B1 (fr) * 2000-02-04 2002-06-28 Goemar Lab Sa Procede pour la preparation de derives fonctionnalises de beta-(1,3)-glucanes
WO2003095842A1 (de) * 2002-05-07 2003-11-20 Emu Unterwasserpumpen Gmbh Antriebsmotor, insbesondere für eine pumpe
JP5014573B2 (ja) * 2002-05-09 2012-08-29 オンコサイレオン インコーポレーテッド 脂質ａおよび他の炭水化物リガンド類似体
AU2003289493A1 (en) * 2002-12-24 2004-07-22 Mochizuki, Takashi Lipid a analogues having glucose as the right sugar
RU2396960C2 (ru) * 2004-07-23 2010-08-20 Ом Фарма Комбинированная противоопухолевая терапия и фармацевтические композиции для нее
EP2678005A4 (en) 2011-02-24 2015-06-10 Oncothyreon Inc GLUCOLOPOPEPTIDE MUC1-BASED VACCINE WITH AN ADJUVANS
US9241988B2 (en) * 2012-04-12 2016-01-26 Avanti Polar Lipids, Inc. Disaccharide synthetic lipid compounds and uses thereof

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2477551A1 (fr) * 1980-03-10 1981-09-11 Anvar Nouveaux derives de l'a, a'-trehalose et medicaments les contenant
AU561066B2 (en) * 1982-03-22 1987-04-30 Biocarb Ab Antibacterial composition containing an oligosaccharide
US4515782A (en) * 1983-08-29 1985-05-07 American Cyanamid Company Substituted phenyl-1-thio(poly-O-sulfo)-α(or β)-D-glucopyranosides

Also Published As

Publication number Publication date
FI860747A7 (fi) 1986-08-23
EP0192296B1 (en) 1988-12-28
JPS61246195A (ja) 1986-11-01
US4719202A (en) 1988-01-12
ES8707967A1 (es) 1987-09-01
CA1259308A (en) 1989-09-12
PT82067B (en) 1987-07-20
ES552297A0 (es) 1987-09-01
DK83386A (da) 1986-08-23
EP0192296A1 (en) 1986-08-27
GR860379B (en) 1986-06-11
DE3661538D1 (en) 1989-02-02
AU583093B2 (en) 1989-04-20
PT82067A (en) 1986-03-01
AU5348886A (en) 1986-08-28
DK83386D0 (da) 1986-02-21
FI860747A0 (fi) 1986-02-20
KR860006479A (ko) 1986-09-11

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