ZA868516B - Method for preparing antihemophilic factor(ahf)by cold precipitation and for improving solubility of recovered ahf product - Google Patents

Method for preparing antihemophilic factor(ahf)by cold precipitation and for improving solubility of recovered ahf product

Info

Publication number: ZA868516B
Authority: ZA; South Africa
Prior art keywords: ahf; cold precipitation; fibrinogen; product; fibronectin
Prior art date: 1985-11-08

Application number

ZA868516A

Other languages

English (en)

Inventor

Maria Erlinda C Sarno

Clifford R Graf

Rodolfo A Vasquez

Original Assignee

Baxter Travenol Lab

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1985-11-08

Filing date

1986-11-10

Publication date

1987-08-26

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=25168481&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA868516(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

1986-11-10 Application filed by Baxter Travenol Lab filed Critical Baxter Travenol Lab

1987-08-26 Publication of ZA868516B publication Critical patent/ZA868516B/xx

Links

102100026735 Coagulation factor VIII Human genes 0.000 title abstract 6
101000911390 Homo sapiens Coagulation factor VIII Proteins 0.000 title abstract 6
238000000034 method Methods 0.000 title abstract 4
238000001556 precipitation Methods 0.000 title abstract 4
102000008946 Fibrinogen Human genes 0.000 abstract 3
108010049003 Fibrinogen Proteins 0.000 abstract 3
102000016359 Fibronectins Human genes 0.000 abstract 3
108010067306 Fibronectins Proteins 0.000 abstract 3
239000002202 Polyethylene glycol Substances 0.000 abstract 3
229940012952 fibrinogen Drugs 0.000 abstract 3
229920001223 polyethylene glycol Polymers 0.000 abstract 3
BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 abstract 1
229910001424 calcium ion Inorganic materials 0.000 abstract 1
239000000356 contaminant Substances 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
238000001914 filtration Methods 0.000 abstract 1
210000002381 plasma Anatomy 0.000 abstract 1
238000011084 recovery Methods 0.000 abstract 1

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers
- A61K9/1272—Non-conventional liposomes, e.g. PEGylated liposomes or liposomes coated or grafted with polymers comprising non-phosphatidyl surfactants as bilayer-forming substances, e.g. cationic lipids or non-phosphatidyl liposomes coated or grafted with polymers
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/745—Blood coagulation or fibrinolysis factors
- C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Engineering & Computer Science (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Pharmacology & Pharmacy (AREA)
Organic Chemistry (AREA)
Nanotechnology (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Bioinformatics & Cheminformatics (AREA)
Animal Behavior & Ethology (AREA)
Hematology (AREA)
Medical Informatics (AREA)
Crystallography & Structural Chemistry (AREA)
Gastroenterology & Hepatology (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Toxicology (AREA)
Epidemiology (AREA)
Dispersion Chemistry (AREA)
Biotechnology (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Diabetes (AREA)
Peptides Or Proteins (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Manufacture Of Macromolecular Shaped Articles (AREA)
Compounds Of Unknown Constitution (AREA)
Saccharide Compounds (AREA)

ZA868516A 1985-11-08 1986-11-10 Method for preparing antihemophilic factor(ahf)by cold precipitation and for improving solubility of recovered ahf product ZA868516B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US79655985A	1985-11-08	1985-11-08

Publications (1)

Publication Number	Publication Date
ZA868516B true ZA868516B (en)	1987-08-26

Family

ID=25168481

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA868516A ZA868516B (en)	1985-11-08	1986-11-10	Method for preparing antihemophilic factor(ahf)by cold precipitation and for improving solubility of recovered ahf product

Country Status (9)

Country	Link
US (1)	US4739039A (fr)
EP (1)	EP0221566B1 (fr)
JP (1)	JPH0822879B2 (fr)
AT (1)	ATE79266T1 (fr)
AU (1)	AU6487286A (fr)
CA (1)	CA1293941C (fr)
DE (1)	DE3686390T2 (fr)
ES (1)	ES2051686T3 (fr)
ZA (1)	ZA868516B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB8505882D0 (en) *	1985-03-07	1985-04-11	Central Blood Lab Authority	Purification of blood coagulation factor viii
DE3806562A1 (de) *	1988-03-01	1989-09-14	Alpha Therapeutic Gmbh	Zweikammerspritze mit einer fuellung aus aktivitaetsempfindlichem humanen protein als wirkstoff
DE69002033T2 (de) *	1989-05-24	1993-09-30	Miles Inc	Gelfiltration von wärmebehandeltem Faktor VIII.
DE3926034C3 (de) *	1989-08-07	1996-11-21	Behringwerke Ag	Verfahren zur Herstellung eines stabilen Faktors VIII
IT1248723B (it) *	1990-06-12	1995-01-26	Scalvo S P A	Processo per la purificazione del fattore viii e fattore viii ottenuto con tale processo
US5259971A (en) *	1992-03-02	1993-11-09	Cryolife, Inc.	Method of preparing fibrinogen
US5330974A (en) *	1993-03-01	1994-07-19	Fibratek, Inc.	Therapeutic fibrinogen compositions
US5523893A (en) *	1994-08-24	1996-06-04	Northrop Grumman Corporation	Strain free temperature-compensated optical mounts
GB9424732D0 (en) *	1994-12-08	1995-02-08	Common Services Agency	Heat treated blood plasma proteins
US5659017A (en) *	1995-11-07	1997-08-19	Alpha Therapeutic Corporation	Anion exchange process for the purification of Factor VIII
DK1820516T3 (da)	1999-02-22	2013-10-28	Univ Connecticut	Nye albuminfrie faktor VIII-præparater
MX339060B (es)	2008-11-07	2016-05-09	Baxter Int	Formulaciones del factor viii.
SG10201811186XA (en)	2013-10-18	2019-01-30	Novasep Process	Purification of proteins

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
BE713764A (fr) *	1967-05-01	1968-09-16	Baxter Travenol Lab
US3652530A (en) *	1967-08-28	1972-03-28	American Nat Red Cross	Antihemophilic factor prepared from blood plasma using polyethylene glycol
GB1507198A (en) *	1974-04-12	1978-04-12	Squibb & Sons Inc	Antihemophilic factor
US4069216A (en) *	1975-06-16	1978-01-17	Edward Shanbrom, Inc.	Simplified methods for preparation of very high purity Factor VIII concentrate
CA1054052A (fr) *	1976-08-14	1979-05-08	Edward Shanbrom	Methode simplifiee pour la preparation d'un concentre de facteur viii hautement purifie
US4104266A (en) *	1977-04-14	1978-08-01	American National Red Cross	Method for preparation of antihemophilic factor
FR2460305A2 (fr) *	1979-06-29	1981-01-23	Merieux Inst	Procede de preparation d'un concentre de facteur viii
US4289691A (en) *	1980-01-18	1981-09-15	The Canadian Red Cross Society	Method of obtaining intermediate purity factor VIII
US4386068A (en) *	1980-02-26	1983-05-31	Cutter Laboratories, Inc.	Antihemophilic factor concentrate and method for preparation
US4294826A (en) *	1980-05-07	1981-10-13	Armour Pharmaceutical Company	Process for the preparation of highly purified antihemophilic factor
AT369263B (de) *	1980-08-27	1982-12-27	Immuno Ag	Verfahren zur herstellung eines faktor viii(ahf) -hochkonzentrates
US4406886A (en) *	1983-01-14	1983-09-27	University Patents, Inc.	Purification of antihemophilia factor VIII by precipitation with zinc ions
DE3318521A1 (de) *	1983-05-20	1984-11-22	Lentia GmbH Chem. u. pharm. Erzeugnisse - Industriebedarf, 8000 München	Verfahren zur herstellung eines antihaemophiliefaktor-konzentrats
US4543210A (en) *	1984-10-04	1985-09-24	Miles Laboratories, Inc.	Process for producing a high purity antihemophilic factor concentrate

1986
- 1986-11-06 CA CA000522350A patent/CA1293941C/fr not_active Expired - Lifetime
- 1986-11-06 AU AU64872/86A patent/AU6487286A/en not_active Abandoned
- 1986-11-07 JP JP61266504A patent/JPH0822879B2/ja not_active Expired - Lifetime
- 1986-11-07 AT AT86115463T patent/ATE79266T1/de not_active IP Right Cessation
- 1986-11-07 DE DE8686115463T patent/DE3686390T2/de not_active Expired - Lifetime
- 1986-11-07 EP EP86115463A patent/EP0221566B1/fr not_active Expired - Lifetime
- 1986-11-07 ES ES86115463T patent/ES2051686T3/es not_active Expired - Lifetime
- 1986-11-10 ZA ZA868516A patent/ZA868516B/xx unknown
1987
- 1987-07-15 US US07/073,380 patent/US4739039A/en not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU6487286A (en)	1987-05-14
EP0221566B1 (fr)	1992-08-12
EP0221566A2 (fr)	1987-05-13
JPS62181220A (ja)	1987-08-08
EP0221566A3 (en)	1987-10-07
CA1293941C (fr)	1992-01-07
US4739039A (en)	1988-04-19
DE3686390D1 (de)	1992-09-17
ES2051686T3 (es)	1994-07-01
DE3686390T2 (de)	1993-03-04
ATE79266T1 (de)	1992-08-15
JPH0822879B2 (ja)	1996-03-06

Publication	Publication Date	Title
EP0221566A3 (en)	1987-10-07	Method for preparing antihemophilic factor (ahf) by cold precipitation and for improving solubility of recovered ahf product
IL122665A (en)	2001-08-26	Method and apparatus for inactivating contaminants in blood products
ATE305011T1 (de)	2005-10-15	Verfahren zur herstellung von virusfreien thrombin zur bereitung von fibrinkleber aus menschlichem plasma-pool
ATE91896T1 (de)	1993-08-15	Verfahren zur herstellung eines konzentrats des faktor viii-von willebrand-faktor-komplexes der blutgerinnung aus vollplasma.
EP0125520A3 (fr)	1987-06-16	Procédé et installation pour la récupération d'un ou de plusieurs constituants d'un mélange gazeux
ES477942A1 (es)	1980-04-01	Procedimiento para el tratamiento de soluciones acuosas impuras de oxido de etileno.
EP0022052A3 (fr)	1981-11-11	Procédé pour la séparation et l'isolement de la fraction AHF (facteur antihémophilique), la fraction fibronectine et la fraction Von Willebrand's ristocétine cofacteur à partir du plasma sanguin
GR3026053T3 (en)	1998-05-29	Recovery of citric acid from impure process streams by addition of strong acids and salts thereof.
US4404131A (en)	1983-09-13	Method of producing a factor-VIII(AHF)-high-concentrate
EP0399573A3 (fr)	1990-12-19	Procédé pour la récupération d'amino acides de mélanges aqueux
DE69311337D1 (de)	1997-07-10	Verfahren zur Reinigung von Proteinen
KR880000465A (ko)	1988-03-26	순수한 알부민의 제조방법
ES2054751T3 (es)	1994-08-16	Metodo de purificacion de agarosa usando un glicol.
DE69012579D1 (de)	1994-10-20	Verfahren zur rückgewinnung rekombinanter proteine unter verwendung von flockungsmitteln.
FR2632302B1 (fr)	1991-02-22	Procede de recuperation d'acide citrique a partir d'une liqueur en contenant
HUT61053A (en)	1992-11-30	Process for obtaining recombinant proteins
GR3007446T3 (fr)	1993-07-30
EP0237981A3 (fr)	1989-07-26	Procédé de production d'une préparation stérile contenant le facteur VIII de coagulation du sang
ATE44750T1 (de)	1989-08-15	Verfahren zur herstellung eines antihaemophiliefaktor-konzentrats.
ATE35533T1 (de)	1988-07-15	Verfahren zur rueckgewinnung von reiner benzoesaeure.
ATE138046T1 (de)	1996-06-15	Verfahren zur entfernung von abgelagerten verunreinigungen in einem organischen strom zur erzeugung reiner phosphorsäure
DE69525948D1 (de)	2002-04-25	Verfahren zur wiedergewinnung von zitronensäure
TW254947B (en)	1995-08-21	An improved process for hemoglobin purification
MX9701265A (es)	1997-05-31	Procedimiento para tratar una corriente acuosa de desechos de fluoruro de potasio y para convertir este fluoruro de potasio en fluoruro de hidrogeno e hidroxido de potasio.