ZA869588B - 5,6-dialkoxy-4-imino-2(1h)quinazolinone derivatives - Google Patents

5,6-dialkoxy-4-imino-2(1h)quinazolinone derivatives

Info

Publication number
ZA869588B
ZA869588B ZA869588A ZA869588A ZA869588B ZA 869588 B ZA869588 B ZA 869588B ZA 869588 A ZA869588 A ZA 869588A ZA 869588 A ZA869588 A ZA 869588A ZA 869588 B ZA869588 B ZA 869588B
Authority
ZA
South Africa
Prior art keywords
dialkoxy
imino
quinazolinone derivatives
quinazolinone
derivatives
Prior art date
Application number
ZA869588A
Other languages
English (en)
Inventor
Victor T Bandurco
Stanley C Bell
Robert Falotico
Charles F Schwender
Alfonso J Tobia
Original Assignee
Ortho Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ortho Pharma Corp filed Critical Ortho Pharma Corp
Publication of ZA869588B publication Critical patent/ZA869588B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/95—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in positions 2 and 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA869588A 1985-12-20 1986-12-19 5,6-dialkoxy-4-imino-2(1h)quinazolinone derivatives ZA869588B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/811,238 US4668787A (en) 1985-12-20 1985-12-20 5,6-dialkoxy-4-imino-2(1H)quinazolinone derivatives

Publications (1)

Publication Number Publication Date
ZA869588B true ZA869588B (en) 1988-07-27

Family

ID=25205981

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA869588A ZA869588B (en) 1985-12-20 1986-12-19 5,6-dialkoxy-4-imino-2(1h)quinazolinone derivatives

Country Status (6)

Country Link
US (1) US4668787A (da)
EP (1) EP0227451A3 (da)
JP (1) JPS62187461A (da)
AU (1) AU6675386A (da)
DK (1) DK615086A (da)
ZA (1) ZA869588B (da)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2077252C (en) * 1992-08-31 2001-04-10 Khashayar Karimian Methods of making ureas and guanidines, and intermediates therefor
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
EP2671508B1 (en) 2005-04-28 2020-09-16 Proteus Digital Health, Inc. Pharma-informatics system
JP2010503710A (ja) 2006-09-18 2010-02-04 ラプトール ファーマシューティカル インコーポレイテッド 受容体関連タンパク質（ｒａｐ）結合体の投与による肝障害の処置
ES2919563T3 (es) 2009-02-20 2022-07-27 Enhanx Biopharm Inc Sistema de administración de medicamentos a base de glutatión
KR20180114970A (ko) 2009-05-06 2018-10-19 라보라토리 스킨 케어, 인크. 활성제-칼슘 포스페이트 입자 복합체를 포함하는 피부 전달 조성물 및 이들을 이용하는 방법
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
WO2018107201A1 (en) * 2016-12-13 2018-06-21 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof
MX2019006863A (es) 2016-12-13 2019-09-13 Beta Therapeutics Pty Ltd Inhibidores de heparanasa y uso de los mismos.
US11787783B2 (en) 2016-12-13 2023-10-17 Beta Therapeutics Pty Ltd Heparanase inhibitors and use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3516816A (en) * 1967-05-19 1970-06-23 United States Borax Chem Herbicidal compositions and methods utilizing alkyleneiminourea compounds
CH507917A (de) * 1969-03-12 1971-05-31 Agripat Sa Verfahren zur Herstellung neuer 2-Ureido-benzamide und deren Verwendung zur Unkrautbekämpfung
US4146717A (en) * 1972-04-07 1979-03-27 Sumitomo Chemical Company, Limited Nitroquinazolinone compounds having antiviral properties
US4287341A (en) * 1979-11-01 1981-09-01 Pfizer Inc. Alkoxy-substituted-6-chloro-quinazoline-2,4-diones
US4634769A (en) * 1984-09-25 1987-01-06 Ortho Pharmaceutical Corporation Process for the preparation of 8-halo-5,6-dialkoxyquinazoline-2,4-diones and their salts

Also Published As

Publication number Publication date
EP0227451A3 (en) 1988-01-13
AU6675386A (en) 1987-06-25
EP0227451A2 (en) 1987-07-01
JPS62187461A (ja) 1987-08-15
US4668787A (en) 1987-05-26
DK615086D0 (da) 1986-12-18
DK615086A (da) 1987-06-21

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