ZA871948B - Anticholinergic compounds,pharmaceutical compositions and method of treatment - Google Patents

Anticholinergic compounds,pharmaceutical compositions and method of treatment

Info

Publication number
ZA871948B
ZA871948B ZA871948A ZA871948A ZA871948B ZA 871948 B ZA871948 B ZA 871948B ZA 871948 A ZA871948 A ZA 871948A ZA 871948 A ZA871948 A ZA 871948A ZA 871948 B ZA871948 B ZA 871948B
Authority
ZA
South Africa
Prior art keywords
opt
alkyl
substd
toxic
treatment
Prior art date
Application number
ZA871948A
Other languages
English (en)
Inventor
H. Hammer Richard
S. Bodor Nicholas
Original Assignee
University Of Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University Of Florida filed Critical University Of Florida
Publication of ZA871948B publication Critical patent/ZA871948B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
    • C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
    • C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
    • C07D451/06—Oxygen atoms
    • C07D451/10—Oxygen atoms acylated by aliphatic or araliphatic carboxylic acids, e.g. atropine, scopolamine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/02—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D225/00—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom
    • C07D225/04—Heterocyclic compounds containing rings of more than seven members having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Biomedical Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)
  • Pyridine Compounds (AREA)
ZA871948A 1986-03-17 1987-03-17 Anticholinergic compounds,pharmaceutical compositions and method of treatment ZA871948B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US83994186A 1986-03-17 1986-03-17

Publications (1)

Publication Number Publication Date
ZA871948B true ZA871948B (en) 1987-09-07

Family

ID=25281041

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA871948A ZA871948B (en) 1986-03-17 1987-03-17 Anticholinergic compounds,pharmaceutical compositions and method of treatment

Country Status (14)

Country Link
EP (1) EP0238982B1 (fr)
JP (1) JP2672311B2 (fr)
KR (1) KR900007218B1 (fr)
AT (1) ATE86622T1 (fr)
CA (1) CA1328106C (fr)
DE (1) DE3784531T2 (fr)
DK (1) DK170560B1 (fr)
ES (1) ES2044851T3 (fr)
FI (1) FI87213C (fr)
IE (1) IE60645B1 (fr)
NO (1) NO874765L (fr)
NZ (1) NZ219653A (fr)
WO (1) WO1987005603A1 (fr)
ZA (1) ZA871948B (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW200524577A (en) * 2003-11-04 2005-08-01 Glaxo Group Ltd Muscarinic acetylcholine receptor antagonists
EP1785421A1 (fr) * 2004-08-30 2007-05-16 Ono Pharmaceutical Co., Ltd. Dérivé du tropane
CN113321648B (zh) * 2021-05-21 2022-02-11 常州康普药业有限公司 一种硫酸阿托品的合成方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2814623A (en) * 1955-12-05 1957-11-26 Upjohn Co Certain esters of n-methyl scopolamine quaternary ammonium salts
DE1670048C3 (de) * 1966-01-26 1980-09-04 C.H. Boehringer Sohn, 6507 Ingelheim Neue Norscopolaminderivate
NL7002588A (fr) * 1969-03-04 1970-09-08
US3998815A (en) * 1974-06-24 1976-12-21 Interx Research Corporation 1-hydrocarbonoyloxymethyl-3-carbamoyl or 3-carboethoxy-pyridinium salts

Also Published As

Publication number Publication date
KR900007218B1 (ko) 1990-10-05
CA1328106C (fr) 1994-03-29
IE870698L (en) 1987-09-17
DK567887D0 (da) 1987-10-30
EP0238982A1 (fr) 1987-09-30
KR880701230A (ko) 1988-07-26
DK567887A (da) 1987-10-30
ES2044851T3 (es) 1994-01-16
DK170560B1 (da) 1995-10-23
AU7203187A (en) 1987-10-09
FI87213B (fi) 1992-08-31
FI87213C (fi) 1992-12-10
NO874765L (no) 1988-01-14
JPS63502898A (ja) 1988-10-27
NO874765D0 (no) 1987-11-16
NZ219653A (en) 1990-02-26
JP2672311B2 (ja) 1997-11-05
EP0238982B1 (fr) 1993-03-10
DE3784531D1 (de) 1993-04-15
FI874937A0 (fi) 1987-11-09
IE60645B1 (en) 1994-08-10
WO1987005603A1 (fr) 1987-09-24
ATE86622T1 (de) 1993-03-15
FI874937A7 (fi) 1987-11-09
AU595307B2 (en) 1990-03-29
DE3784531T2 (de) 1993-06-24

Similar Documents

Publication Publication Date Title
NO885352D0 (no) Vannloeselige camptothecin-analoger.
KR850002741A (ko) 페닐에탄올아민 유도체의 제조방법
MY131501A (en) Process for the prepration of clavulanic acid
SU1181541A3 (ru) &#34;cпocoб пoлучehия -зameщehhыx пpoизboдhыx aзиpидиh-2-kapбohoboй kиcлotы или иx coлeй&#34;
HUT41713A (en) Process for production of //arol-cyclobutyl/ alkyl/-amins and medical preparatives containing thereof
HUT49889A (en) Process for producing acyl derivatives
PT83104B (en) Novel guanidinomethylbenzoic acid derivatives
YU224790A (sh) Aminokarbonil karbamati, sorodni fizostigminu/in postopek za njihovo pripravo in njihova uporaba kot zdravila
ES2012507A6 (es) Un procedimiento para la preparacion de derivados de b-lactama.
GB1531963A (en) Pyrido(1,2alpha)pyrimidine derivatives
NO874765D0 (no) Anticholinforbindelser, farmasoeytiske blandinger og behandlingsmetode.
ZA762889B (en) New n-substituted derivatives of phenylpiperidine and their salts process for preparing these and pharmaceutical compositions
MY102310A (en) New 5-oxy deravatives of tetrahydrofuran
GB1513883A (en) 3-(4-amino-and 4-acylamino-piperazin-1-ylalkyl)indoles
PT81369A (en) Process for the preparation of a plant growth regulating and/or fungicidal compositions containing substituted azolylcyclopropyl-azolylmethyl-carbinol derivatives
NO861630L (no) Karbapenemderivater og fremgangsmaate til fremstilling derav.
BG40962A3 (en) Method for preparing n- substituted n- (dichloracetyl)- glycinamides
ES8200347A1 (es) Procedimiento de preparacion de derivados de la piridina.
GB1464431A (en) Indolobenzazepine derivatives and a process for the manufacture thereof
EP0119540A3 (en) Substituted alkylamine derivatives of 6,11-dihydro-11-oxodibenz (b,e)-oxepins, a process for the preparation and intermediates thereof and their use as medicaments
IE42666L (en) Deoxyclavulanic acid and deoxyisoclavulanic acid and¹derivatives thereof
RU94042399A (ru) Получения клавулановой кислоты из соли клавулановой кислоты и амина, соли клавулановой кислоты и амина
IE42766L (en) Pharmaceutical preparations
GB1449159A (en) Benzoisoindoline derivatives
GB1383765A (en) Esters of guanidino penicillins