ZA874863B - Novel 18-phenyloestrane derivatives - Google Patents

Novel 18-phenyloestrane derivatives

Info

Publication number
ZA874863B
ZA874863B ZA874863A ZA874863A ZA874863B ZA 874863 B ZA874863 B ZA 874863B ZA 874863 A ZA874863 A ZA 874863A ZA 874863 A ZA874863 A ZA 874863A ZA 874863 B ZA874863 B ZA 874863B
Authority
ZA
South Africa
Prior art keywords
phenyloestrane
derivatives
novel
phenyloestrane derivatives
Prior art date
Application number
ZA874863A
Other languages
English (en)
Inventor
Paul De Jongh Hendrik
Johannes Van Den Heuvel Martinus
Original Assignee
Akzo N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo N.V. filed Critical Akzo N.V.
Publication of ZA874863B publication Critical patent/ZA874863B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0044—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an estrane or gonane skeleton, including 18-substituted derivatives and derivatives where position 17-beta is substituted by a carbon atom not directly bonded to another carbon atom and not being part of an amide group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Reproductive Health (AREA)
  • Endocrinology (AREA)
  • Urology & Nephrology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
ZA874863A 1986-07-23 1987-07-03 Novel 18-phenyloestrane derivatives ZA874863B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8601903 1986-07-23

Publications (1)

Publication Number Publication Date
ZA874863B true ZA874863B (en) 1988-01-13

Family

ID=19848343

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA874863A ZA874863B (en) 1986-07-23 1987-07-03 Novel 18-phenyloestrane derivatives

Country Status (15)

Country Link
US (1) US4808710A (da)
EP (1) EP0254341B1 (da)
JP (1) JPS6335595A (da)
KR (1) KR880001693A (da)
CN (1) CN87106126A (da)
AU (1) AU598836B2 (da)
CA (1) CA1284318C (da)
DE (1) DE3761308D1 (da)
DK (1) DK383887A (da)
ES (1) ES2015047B3 (da)
FI (1) FI84274C (da)
GR (1) GR3001005T3 (da)
NZ (1) NZ221019A (da)
PT (1) PT85395B (da)
ZA (1) ZA874863B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4992485A (en) * 1988-10-11 1991-02-12 The Dow Chemical Company Microporous peek membranes and the preparation thereof
DE3921059A1 (de) * 1989-06-23 1991-01-10 Schering Ag 11(beta)-aryl-4-estrene, verfahren zu ihrer herstellung sowie deren verwendung als arzneimittel
ZA929315B (en) * 1991-12-20 1993-05-24 Akzo Nv 17-spirofuran-3'-ylidene steroids.
AU710139B2 (en) * 1996-05-01 1999-09-16 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The 21-substituted progesterone derivatives as new antiprogestational agents
US6900193B1 (en) * 1996-05-01 2005-05-31 The United States Of America As Represented By The Department Of Health And Human Services Structural modification of 19-norprogesterone I: 17-α-substituted-11-β-substituted-4-aryl and 21-substituted 19-norpregnadienedione as new antiprogestational agents
AU2004217988C1 (en) * 2003-02-28 2010-06-03 Southwest Foundation For Biomedical Research Method for preparing 17 alpha-acetoxy-11beta-(4-N,N-dimethylaminophenyl)-19-norpregna-4,9-diene-3,20-dione, intermediates thereof, and methods for the preparation of such intermediates
RU2397176C2 (ru) 2004-01-07 2010-08-20 Эндорешерш, Инк. Стероидные фармацевтические продукты, направленные на спираль 12
US7709516B2 (en) 2005-06-17 2010-05-04 Endorecherche, Inc. Helix 12 directed non-steroidal antiandrogens
EP2576582B1 (en) 2010-05-26 2019-09-18 Corcept Therapeutics, Inc. Treatment of muscular dystrophy
CN107530435A (zh) 2015-03-02 2018-01-02 科赛普特治疗学股份有限公司 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤
WO2016160969A1 (en) 2015-03-30 2016-10-06 Corcept Therapeutics, Inc. Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency
ES2865334T3 (es) 2015-08-13 2021-10-15 Corcept Therapeutics Inc Método de diagnóstico diferencial de síndrome de Cushing dependiente de ACTH
CA3011728A1 (en) 2016-01-19 2017-07-27 Corcept Therapeutics, Inc. Differential diagnosis of ectopic cushing's syndrome
CA3055076C (en) 2017-03-31 2022-02-22 Corcept Therapeutics, Inc. Glucocorticoid receptor modulators to treat cervical cancer
AU2018289307B2 (en) 2017-06-20 2024-02-01 Corcept Therapeutics, Inc. Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators
AU2020239920A1 (en) 2019-03-18 2021-11-04 Arnold L. Newman Method of improving insulin sensitivity
EP4263807A2 (en) 2020-12-18 2023-10-25 Instil Bio (Uk) Limited Processing of tumor infiltrating lymphocytes

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1255345A (en) * 1916-05-20 1918-02-05 Arthur L Shaw Conveyer.
US3100204A (en) * 1960-04-20 1963-08-06 Merck & Co Inc Haloethisterone compounds
US3074978A (en) * 1961-01-11 1963-01-22 Roussel Uclaf Process for the preparation of 13beta-n-propyl-delta4-gonene-17beta-ol-3-one and the intermediates in the preparation thereof
US3177205A (en) * 1963-03-01 1965-04-06 Syntex Corp 19-lower-alkyl-10alpha-derivatives of cortical hormones
JPS4118820Y1 (da) * 1965-09-22 1966-09-02
BE697838A (da) * 1966-11-11 1967-10-02
US3725439A (en) * 1971-01-07 1973-04-03 Merck & Co Inc 13-carbocyclic-3-keto-4-gonenes
US4167517A (en) * 1976-06-14 1979-09-11 Veb Jenapharm Gona-4,9(10)-dienes and process of producing the same
ZA8231B (en) * 1981-01-09 1982-11-24 Roussel Uclaf New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained

Also Published As

Publication number Publication date
JPS6335595A (ja) 1988-02-16
ES2015047B3 (es) 1990-08-01
CN87106126A (zh) 1988-05-11
CA1284318C (en) 1991-05-21
NZ221019A (en) 1989-12-21
EP0254341A1 (en) 1988-01-27
FI84274C (fi) 1991-11-11
FI84274B (fi) 1991-07-31
AU7596987A (en) 1988-01-28
FI873193A0 (fi) 1987-07-20
PT85395B (pt) 1990-04-30
PT85395A (en) 1987-08-01
EP0254341B1 (en) 1990-01-03
DK383887A (da) 1988-01-24
GR3001005T3 (en) 1991-12-30
US4808710A (en) 1989-02-28
DK383887D0 (da) 1987-07-22
AU598836B2 (en) 1990-07-05
DE3761308D1 (de) 1990-02-08
FI873193A7 (fi) 1988-01-24
KR880001693A (ko) 1988-04-26

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