ZA882282B - Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furan derivatives the processes for preparing them and the pharmaceutical compositions which contain them - Google Patents
Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furan derivatives the processes for preparing them and the pharmaceutical compositions which contain themInfo
- Publication number
- ZA882282B ZA882282B ZA882282A ZA882282A ZA882282B ZA 882282 B ZA882282 B ZA 882282B ZA 882282 A ZA882282 A ZA 882282A ZA 882282 A ZA882282 A ZA 882282A ZA 882282 B ZA882282 B ZA 882282B
- Authority
- ZA
- South Africa
- Prior art keywords
- radical
- carbon atoms
- linear
- amino
- denotes
- Prior art date
Links
- VQXDQAATJUJGME-UHFFFAOYSA-N 5,6,7,8-tetrahydrobenzo[f][1]benzofuran-2-amine Chemical class C1CCCC2=C1C=C1C=C(N)OC1=C2 VQXDQAATJUJGME-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- -1 alkyl radical Chemical class 0.000 abstract 11
- 125000004432 carbon atom Chemical group C* 0.000 abstract 7
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- MDFFNEOEWAXZRQ-UHFFFAOYSA-N aminyl Chemical compound [NH2] MDFFNEOEWAXZRQ-UHFFFAOYSA-N 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- SLRMQYXOBQWXCR-UHFFFAOYSA-N 2154-56-5 Chemical compound [CH2]C1=CC=CC=C1 SLRMQYXOBQWXCR-UHFFFAOYSA-N 0.000 abstract 1
- 230000001430 anti-depressive effect Effects 0.000 abstract 1
- 239000000935 antidepressant agent Substances 0.000 abstract 1
- 229940005513 antidepressants Drugs 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- ORTFAQDWJHRMNX-UHFFFAOYSA-N hydroxidooxidocarbon(.) Chemical compound O[C]=O ORTFAQDWJHRMNX-UHFFFAOYSA-N 0.000 abstract 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N nitrogen Substances N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- QJGQUHMNIGDVPM-UHFFFAOYSA-N nitrogen group Chemical group [N] QJGQUHMNIGDVPM-UHFFFAOYSA-N 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/92—Naphthofurans; Hydrogenated naphthofurans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8704551A FR2613365B1 (fr) | 1987-04-01 | 1987-04-01 | Nouveaux derives de l'amino tetrahydro-5, 6, 7, 8 naphto (2, 3b) furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA882282B true ZA882282B (en) | 1988-09-22 |
Family
ID=9349665
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA882282A ZA882282B (en) | 1987-04-01 | 1988-03-30 | Amino-5,6,7,8-tetrahydronaphtho(2,3-b)furan derivatives the processes for preparing them and the pharmaceutical compositions which contain them |
Country Status (16)
| Country | Link |
|---|---|
| US (2) | US4863951A (de) |
| EP (1) | EP0286516B1 (de) |
| JP (1) | JPH068286B2 (de) |
| AT (1) | ATE73790T1 (de) |
| AU (1) | AU602565B2 (de) |
| CA (1) | CA1314050C (de) |
| DE (1) | DE3869173D1 (de) |
| DK (1) | DK166496B1 (de) |
| ES (1) | ES2006623A6 (de) |
| FR (1) | FR2613365B1 (de) |
| GR (1) | GR1000155B (de) |
| IE (1) | IE61007B1 (de) |
| NZ (1) | NZ224099A (de) |
| OA (1) | OA08825A (de) |
| PT (1) | PT87147B (de) |
| ZA (1) | ZA882282B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2613364B1 (fr) * | 1987-04-01 | 1989-06-09 | Adir | Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| US5071875A (en) * | 1989-09-25 | 1991-12-10 | Northwestern University | Substituted 2-amidotetralins as melatonin agonists and antagonists |
| FR2689509B1 (fr) * | 1992-04-01 | 1994-06-03 | Adir | Nouveaux derives spiraniques du 3-amino chromane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent. |
| AU679053B2 (en) * | 1993-03-25 | 1997-06-19 | Pharmacia & Upjohn Company | Indoletetralins having dopaminergic activity |
| CN1191243C (zh) * | 1994-07-27 | 2005-03-02 | 范德比尔特大学 | 用作抗炎剂的二氢苯并呋喃和相关化合物 |
| US5674891A (en) * | 1994-07-27 | 1997-10-07 | The Procter & Gamble Company | Dihydrobenzothiophene compounds useful as anti-inflammatory agents |
| US6071946A (en) * | 1994-10-21 | 2000-06-06 | Adir Et Compagnie | Tricyclic urea compounds |
| FR2725985B1 (fr) * | 1994-10-21 | 1996-11-15 | Adir | Nouveaux composes tricycliques, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5998461A (en) * | 1994-10-21 | 1999-12-07 | Adir Et Compagnie | Tricyclic amide compounds |
| FR2739379B1 (fr) * | 1995-09-29 | 1997-10-24 | Adir | Nouveaux composes amines de 5,6,7,8-tetrahydronaphto(2,3-b) furane et d'indano(5,6-b)furane, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
| FR2739855B1 (fr) * | 1995-10-13 | 1997-11-14 | Adir | Nouvelles amines heterocycliques tertiaires, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
| US5672620A (en) * | 1996-02-01 | 1997-09-30 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| US5684031A (en) * | 1996-02-01 | 1997-11-04 | The Procter & Gamble Company | Dihydrobenzofuran and related compounds useful as anti-inflammatory agents |
| DE10041478A1 (de) | 2000-08-24 | 2002-03-14 | Sanol Arznei Schwarz Gmbh | Neue pharmazeutische Zusammensetzung |
| DE10334187A1 (de) * | 2003-07-26 | 2005-03-03 | Schwarz Pharma Ag | Substituierte 2-Aminotetraline zur Behandlung von Depressionen |
| DE10334188B4 (de) * | 2003-07-26 | 2007-07-05 | Schwarz Pharma Ag | Verwendung von Rotigotin zur Behandlung von Depressionen |
| PT2123265E (pt) * | 2008-05-23 | 2012-08-06 | Novaera S R L | Formulações de endipaleno no tratamento da psoríase |
| JP5701213B2 (ja) | 2008-10-10 | 2015-04-15 | インスティチュート オブ ファーマコロジー アンド トキシコロジー アカデミー オブ ミリタリー メディカル サイエンシズ ピー．エル．エー．チャイナ | 新規なドーパミンｄ３受容体リガンド、その調製及び使用 |
| US9227944B2 (en) | 2008-10-10 | 2016-01-05 | Institute Of Pharmacology And Toxicology Academy Of Military Science P.L.A. China | Dopamine D3 receptor ligands and preparation and medical uses of the same |
| TW202220965A (zh) * | 2020-08-06 | 2022-06-01 | 美商塔朵根公司 | 用於心理疾患或心理增強之２－胺基茚滿化合物 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1084440A (en) * | 1963-12-31 | 1967-09-20 | Upjohn Co | Improvements in or relating to (2-aminocycloalkyl) hydroquinones and the manufacturethereof |
| US4470990A (en) * | 1983-03-14 | 1984-09-11 | Ayerst, Mckenna & Harrison Inc. | 6,7,8,9-Tetrahydronaphtho(1,2-B)furan-8-amine derivatives and their use as dopamine receptor stimulants |
| FR2613364B1 (fr) * | 1987-04-01 | 1989-06-09 | Adir | Nouvelles amines tricycliques derivees du tetrahydro-5, 6, 7, 8 naphto (2, 3b) dihydro-2, 3 furanne, et du tetrahydro-6, 7, 8, 9 5h-benzocyclohepta (2, 3b) dihydro-2, 3 furanne, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent |
-
1987
- 1987-04-01 FR FR8704551A patent/FR2613365B1/fr not_active Expired
-
1988
- 1988-03-22 CA CA000562140A patent/CA1314050C/fr not_active Expired - Fee Related
- 1988-03-25 US US07/173,285 patent/US4863951A/en not_active Expired - Fee Related
- 1988-03-30 ZA ZA882282A patent/ZA882282B/xx unknown
- 1988-03-30 ES ES8801011A patent/ES2006623A6/es not_active Expired
- 1988-03-30 DK DK178488A patent/DK166496B1/da not_active IP Right Cessation
- 1988-03-31 JP JP63080188A patent/JPH068286B2/ja not_active Expired - Lifetime
- 1988-03-31 NZ NZ224099A patent/NZ224099A/xx unknown
- 1988-03-31 GR GR880100208A patent/GR1000155B/el unknown
- 1988-03-31 IE IE97188A patent/IE61007B1/en not_active IP Right Cessation
- 1988-03-31 EP EP88400780A patent/EP0286516B1/de not_active Expired - Lifetime
- 1988-03-31 AT AT88400780T patent/ATE73790T1/de active
- 1988-03-31 DE DE8888400780T patent/DE3869173D1/de not_active Expired - Lifetime
- 1988-03-31 OA OA59315A patent/OA08825A/xx unknown
- 1988-03-31 AU AU14049/88A patent/AU602565B2/en not_active Ceased
- 1988-03-31 PT PT87147A patent/PT87147B/pt not_active IP Right Cessation
-
1989
- 1989-01-27 US US07/303,545 patent/US4885373A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2613365A1 (fr) | 1988-10-07 |
| GR1000155B (el) | 1991-09-27 |
| ES2006623A6 (es) | 1989-05-01 |
| DK178488A (da) | 1988-10-02 |
| JPS63258870A (ja) | 1988-10-26 |
| PT87147B (pt) | 1992-07-31 |
| IE880971L (en) | 1988-10-01 |
| PT87147A (pt) | 1988-04-01 |
| US4863951A (en) | 1989-09-05 |
| DK178488D0 (da) | 1988-03-30 |
| IE61007B1 (en) | 1994-09-07 |
| GR880100208A (en) | 1989-01-31 |
| DK166496B1 (da) | 1993-06-01 |
| NZ224099A (en) | 1990-05-28 |
| US4885373A (en) | 1989-12-05 |
| EP0286516B1 (de) | 1992-03-18 |
| FR2613365B1 (fr) | 1989-07-28 |
| EP0286516A1 (de) | 1988-10-12 |
| AU602565B2 (en) | 1990-10-18 |
| CA1314050C (fr) | 1993-03-02 |
| JPH068286B2 (ja) | 1994-02-02 |
| DE3869173D1 (de) | 1992-04-23 |
| OA08825A (fr) | 1989-03-31 |
| ATE73790T1 (de) | 1992-04-15 |
| AU1404988A (en) | 1988-10-06 |
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