ZA885418B - N-substituted benzamines - Google Patents
N-substituted benzaminesInfo
- Publication number
- ZA885418B ZA885418B ZA885418A ZA885418A ZA885418B ZA 885418 B ZA885418 B ZA 885418B ZA 885418 A ZA885418 A ZA 885418A ZA 885418 A ZA885418 A ZA 885418A ZA 885418 B ZA885418 B ZA 885418B
- Authority
- ZA
- South Africa
- Prior art keywords
- benzamines
- substituted
- substituted benzamines
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/08—Bridged systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/14—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing 9-azabicyclo [3.3.1] nonane ring systems, e.g. granatane, 2-aza-adamantane; Cyclic acetals thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
- C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Anesthesiology (AREA)
- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Otolaryngology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB878718345A GB8718345D0 (en) | 1987-08-03 | 1987-08-03 | N-substituted benzamides |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA885418B true ZA885418B (en) | 1989-04-26 |
Family
ID=10621740
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA885418A ZA885418B (en) | 1987-08-03 | 1988-07-25 | N-substituted benzamines |
Country Status (22)
| Country | Link |
|---|---|
| US (2) | US4877780A (de) |
| EP (1) | EP0302699A3 (de) |
| JP (1) | JPS6450883A (de) |
| KR (1) | KR890003760A (de) |
| CN (1) | CN1031701A (de) |
| AU (1) | AU629175B2 (de) |
| CS (1) | CS272794B2 (de) |
| DD (1) | DD282010A5 (de) |
| DK (1) | DK429988A (de) |
| FI (1) | FI883592A7 (de) |
| GB (1) | GB8718345D0 (de) |
| HU (1) | HU200460B (de) |
| IL (1) | IL87080A (de) |
| MX (1) | MX12478A (de) |
| NO (1) | NO168422C (de) |
| NZ (1) | NZ225657A (de) |
| PH (1) | PH25048A (de) |
| PL (1) | PL154302B1 (de) |
| PT (1) | PT88175A (de) |
| RO (1) | RO101203B (de) |
| SU (1) | SU1739849A3 (de) |
| ZA (1) | ZA885418B (de) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4820715A (en) * | 1984-06-28 | 1989-04-11 | Bristol-Myers Company | Anti-emetic quinuclidinyl benzamides |
| DE3782651T2 (de) * | 1987-06-17 | 1993-03-25 | Delagrange Lab | Anwendung von n-(2-(diaethylamino)aethyl)-2-methoxy-4((1-h-4,5-dihydro-2-imidazolyl)amino)-5-chlorobenzamid als anxiolytisches und antipsychotisches mittel. |
| FR2640139A1 (fr) * | 1988-12-14 | 1990-06-15 | Delagrange Laboratoires | Application de benzamides substitues comme gastromoteurs |
| FR2640507A1 (fr) * | 1988-12-20 | 1990-06-22 | Delagrange Laboratoires | Application de benzamides substitues comme anxiolytiques et anti-psychotiques |
| MX9102686A (es) * | 1990-12-27 | 1994-01-31 | Erba Carlo Spa | Carboxamidas de dihidrobenzofurano y proceso para su preparacion. |
| US5395832A (en) * | 1991-02-15 | 1995-03-07 | Hokuriku Seiyaku Co., Ltd. | Benzamide derivatives |
| TW243449B (de) * | 1991-02-15 | 1995-03-21 | Hokuriku Pharmaceutical | |
| PH31171A (en) * | 1992-02-04 | 1998-03-20 | Esai Co Ltd | Aminobenzonic acid derivatives useful for treatinggastrointestinal conditions. |
| US5236931A (en) * | 1992-03-26 | 1993-08-17 | A. H. Robins Company, Incorporated | 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol |
| US5864039A (en) * | 1994-03-30 | 1999-01-26 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzoic acid compounds and use thereof as medicaments |
| US5723103A (en) * | 1994-12-09 | 1998-03-03 | Vanderbilt University | Substituted benzamides and radioligand analogs and methods of use |
| US6083991A (en) | 1997-06-04 | 2000-07-04 | University Of Florida Research Foundation, Inc. | Anti-arrhythmic composition and methods of treatment |
| AR022338A1 (es) | 1999-02-04 | 2002-09-04 | Hokuriku Pharmaceutical | Un compuesto de benzamida, medicamento que lo contiene, y uso para la manufactura de un medicamento para el tratamiento o prevencion de una enfermedad digestiva o para mejorar la movilidad del tracto gastrointestinal. |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| EP1381603A2 (de) | 2000-08-18 | 2004-01-21 | PHARMACIA & UPJOHN COMPANY | Mit aryl gruppen substituierte chinuklidine zur behandlung von krankheiten ( nikotin acetylcholin rezeptor liganden ) |
| US6486172B2 (en) | 2000-08-18 | 2002-11-26 | Pharmacia & Upjohn Company | Quinuclidine-substituted aryl compounds for treatment of disease |
| KR100381886B1 (ko) * | 2001-03-21 | 2003-04-26 | 유니모씨엔티 주식회사 | 무선통신용 중계기의 씨디엠에이 신호 검출장치 |
| PE20021019A1 (es) | 2001-04-19 | 2002-11-13 | Upjohn Co | Grupos azabiciclicos sustituidos |
| BR0212123A (pt) * | 2001-08-24 | 2004-07-20 | Upjohn Co | 7-aza[2.2.1]biciclo-heptanos substituìdos com arila para o tratamento de doenças |
| WO2003028650A2 (en) * | 2001-10-02 | 2003-04-10 | Acadia Pharmaceuticals, Inc. | Benzimidazolidinone derivatives as muscarinic agents |
| JP2005522456A (ja) | 2002-02-15 | 2005-07-28 | ファルマシア・アンド・アップジョン・カンパニー・エルエルシー | Ｃｎｓ関連障害治療のためのアザビシクロ置換ベンゾイルアミドおよびチオアミド |
| WO2003072578A1 (en) * | 2002-02-20 | 2003-09-04 | Pharmacia & Upjohn Company | Azabicyclic compounds with alfa7 nicotinic acetylcholine receptor activity |
| EP2100599A1 (de) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalationszusammensetzung enthaltend Aclidinium zur Behandlung von Asthma sowie chronisch-obstruktiver Lungenerkrankung |
| ES2664599T3 (es) | 2009-05-20 | 2018-04-20 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antagonistas del receptor 5-HT3 de serotonina para uso en el tratamiento de trastornos vestibulares lesionales |
| EP2253316B1 (de) | 2009-05-20 | 2013-08-14 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Serotonin-5-HT3-Rezeptorantagonisten zur Verwendung bei der Behandlung oder Prävention einer Innenohr-Pathologie mit Vestibularisdefiziten |
| EP2510928A1 (de) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium zur Verbesserung der Schlafqualität bei atemwegserkrankten Patienten |
| US9692588B2 (en) | 2015-07-07 | 2017-06-27 | Samsung Electronics Co., Ltd. | System and method for performing synchronization and interference rejection in super regenerative receiver (SRR) |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0068700A1 (de) * | 1981-06-29 | 1983-01-05 | Beecham Group Plc | Azabicycloalkylbenzamide, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zusammensetzungen |
| FR2529548A1 (fr) * | 1982-07-02 | 1984-01-06 | Delalande Sa | Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique |
| EP0099194A3 (de) * | 1982-07-03 | 1984-04-11 | Beecham Group Plc | Benzamide |
| EP0102195A3 (de) * | 1982-08-03 | 1984-04-11 | Beecham Group Plc | Substituierte Azabicycloalkyl-Derivate mit dopaminantagonistischer Wirkung |
| US4808624A (en) * | 1984-06-28 | 1989-02-28 | Bristol-Myers Company | Pharmacologically active substituted benzamides |
| US4820715A (en) * | 1984-06-28 | 1989-04-11 | Bristol-Myers Company | Anti-emetic quinuclidinyl benzamides |
| US4870181A (en) * | 1985-02-04 | 1989-09-26 | A. H. Robins Company, Incorporated | Process for the preparation of 2-alkoxy-N-(1-azabicyclo[2.2.2])octan-3-yl)aminobenzamides |
| EP0220011A3 (de) * | 1985-10-12 | 1990-01-03 | Beecham Group Plc | Verwendung von Azabicycloalkylbenzamiden zur Behandlung von Magen-Darmbewegungskrankheiten, Migräne, Emesis, Migränekopfschmerzen, Trigeminusneuralgie und Arhythmie |
| US4717563A (en) * | 1986-03-05 | 1988-01-05 | A. H. Robins Company, Inc. | 2-alkoxy-N-(1-azabicyclo(2.2.2)oct-3-yl) benzamides and thiobenzamides in a method for alleviating emesis caused by non-platinum anticancer drugs |
-
1987
- 1987-08-03 GB GB878718345A patent/GB8718345D0/en active Pending
-
1988
- 1988-07-12 US US07/217,646 patent/US4877780A/en not_active Expired - Fee Related
- 1988-07-12 IL IL87080A patent/IL87080A/xx unknown
- 1988-07-25 ZA ZA885418A patent/ZA885418B/xx unknown
- 1988-07-27 KR KR1019880009476A patent/KR890003760A/ko not_active Ceased
- 1988-07-29 MX MX1247888A patent/MX12478A/es unknown
- 1988-08-01 PL PL1988274010A patent/PL154302B1/pl unknown
- 1988-08-01 RO RO134752A patent/RO101203B/ro unknown
- 1988-08-01 FI FI883592A patent/FI883592A7/fi not_active Application Discontinuation
- 1988-08-01 CS CS539788A patent/CS272794B2/cs unknown
- 1988-08-02 EP EP88307121A patent/EP0302699A3/de not_active Withdrawn
- 1988-08-02 DK DK429988A patent/DK429988A/da not_active Application Discontinuation
- 1988-08-02 HU HU884067A patent/HU200460B/hu not_active IP Right Cessation
- 1988-08-02 SU SU884356273A patent/SU1739849A3/ru active
- 1988-08-02 PH PH37329A patent/PH25048A/en unknown
- 1988-08-02 JP JP63193323A patent/JPS6450883A/ja active Pending
- 1988-08-02 DD DD88318585A patent/DD282010A5/de not_active IP Right Cessation
- 1988-08-02 AU AU20293/88A patent/AU629175B2/en not_active Ceased
- 1988-08-02 NO NO883428A patent/NO168422C/no unknown
- 1988-08-02 PT PT88175A patent/PT88175A/pt unknown
- 1988-08-02 NZ NZ225657A patent/NZ225657A/en unknown
- 1988-08-03 CN CN88104907A patent/CN1031701A/zh active Pending
-
1989
- 1989-12-04 US US07/445,487 patent/US4937236A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HUT48246A (en) | 1989-05-29 |
| US4877780A (en) | 1989-10-31 |
| AU2029388A (en) | 1989-02-09 |
| JPS6450883A (en) | 1989-02-27 |
| US4937236A (en) | 1990-06-26 |
| PH25048A (en) | 1991-01-28 |
| FI883592A0 (fi) | 1988-08-01 |
| KR890003760A (ko) | 1989-04-17 |
| NO168422B (no) | 1991-11-11 |
| MX12478A (es) | 1993-12-01 |
| NO883428D0 (no) | 1988-08-02 |
| CS539788A2 (en) | 1990-06-13 |
| DK429988D0 (da) | 1988-08-02 |
| NO883428L (no) | 1989-02-06 |
| PL154302B1 (en) | 1991-07-31 |
| NO168422C (no) | 1992-02-19 |
| PT88175A (pt) | 1989-06-30 |
| CN1031701A (zh) | 1989-03-15 |
| DK429988A (da) | 1989-04-05 |
| PL274010A1 (en) | 1989-10-16 |
| NZ225657A (en) | 1991-07-26 |
| AU629175B2 (en) | 1992-10-01 |
| GB8718345D0 (en) | 1987-09-09 |
| FI883592A7 (fi) | 1989-02-04 |
| SU1739849A3 (ru) | 1992-06-07 |
| IL87080A0 (en) | 1988-12-30 |
| EP0302699A2 (de) | 1989-02-08 |
| HU200460B (en) | 1990-06-28 |
| CS272794B2 (en) | 1991-02-12 |
| RO101203B (ro) | 1992-01-10 |
| DD282010A5 (de) | 1990-08-29 |
| EP0302699A3 (de) | 1990-07-11 |
| IL87080A (en) | 1992-09-06 |
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