ZA886586B - 2-alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides - Google Patents

2-alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides

Info

Publication number
ZA886586B
ZA886586B ZA886586A ZA886586A ZA886586B ZA 886586 B ZA886586 B ZA 886586B ZA 886586 A ZA886586 A ZA 886586A ZA 886586 A ZA886586 A ZA 886586A ZA 886586 B ZA886586 B ZA 886586B
Authority
ZA
South Africa
Prior art keywords
alkoxy
thiobenzamides
benzamides
azabicyclo
oct
Prior art date
Application number
ZA886586A
Other languages
English (en)
Inventor
Robert John Naylor
John Naylor Robert
Brenda Naylor
Naylor Brenda
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of ZA886586B publication Critical patent/ZA886586B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA886586A 1987-09-04 1988-09-05 2-alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides ZA886586B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878720805A GB8720805D0 (en) 1987-09-04 1987-09-04 2-alkoxy-n-(1-azabicyclo(2 2 2)oct-3-yl)benzamides & thiobenzamides

Publications (1)

Publication Number Publication Date
ZA886586B true ZA886586B (en) 1990-05-30

Family

ID=10623261

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA886586A ZA886586B (en) 1987-09-04 1988-09-05 2-alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamides and thiobenzamides

Country Status (12)

Country Link
US (1) US4877794A (fr)
EP (1) EP0306345B1 (fr)
JP (1) JPH0269417A (fr)
AT (1) ATE88091T1 (fr)
AU (1) AU614768B2 (fr)
CA (1) CA1318595C (fr)
DE (1) DE3880240T2 (fr)
DK (1) DK492688A (fr)
GB (1) GB8720805D0 (fr)
IL (1) IL87662A0 (fr)
PH (1) PH25429A (fr)
ZA (1) ZA886586B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE85217T1 (de) * 1988-08-04 1993-02-15 Synthelabo Antischizophren-wirksame s-n-(1-azabicyclo (2.2.2.>oct-3-yl)benzamide und thiobenzamide.
JPH0669963B2 (ja) * 1989-04-21 1994-09-07 サンド・アクチエンゲゼルシャフト ５ｈｔ▲下３▼受容体拮抗薬の治療的用途
US5236931A (en) * 1992-03-26 1993-08-17 A. H. Robins Company, Incorporated 2-substituted benzamide and benzoate derivatives of 3-aminoquinuclidine and 3-quinuclidinol
US6486172B2 (en) 2000-08-18 2002-11-26 Pharmacia & Upjohn Company Quinuclidine-substituted aryl compounds for treatment of disease
AU2001282874A1 (en) 2000-08-18 2002-03-04 Pharmacia And Upjohn Company Quinuclidine-substituted aryl moieties for treatment of disease (nicotinic acetylcholine receptor ligands)
MXPA04000779A (es) * 2001-08-24 2004-04-20 Pharmacia & Up John Company 7-aza[2.2.1]bicicloheptanos sustituidos con arilo para el tratamiento de enfermedades.
US6852716B2 (en) 2002-02-15 2005-02-08 Pfizer Inc Substituted-aryl compounds for treatment of disease
MXPA04007083A (es) * 2002-02-20 2004-10-29 Upjohn Co Compuestos azabiciclicos para el tratamiento de enfermedades.
FR2861076B1 (fr) * 2003-10-17 2006-01-06 Sanofi Synthelabo Derives de n-heterocyclymethylbenzamide, leur preparation et leur application en therapeutique
WO2010042799A2 (fr) 2008-10-09 2010-04-15 Howard Hughes Medical Institute Canaux ioniques chimériques inédits activés par la fixation d'un ligand et leurs procédés d'utilisation

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7611713A (nl) * 1975-11-03 1977-05-05 Thomae Gmbh Dr K Werkwijze voor de bereiding van verbindingen en preparaten met waardevolle farmacologische eigen- schappen.
FR2531083B1 (fr) * 1982-06-29 1986-11-28 Sandoz Sa Nouveaux derives de la piperidine, leur preparation et leur utilisation comme medicaments
FR2529548A1 (fr) * 1982-07-02 1984-01-06 Delalande Sa Nouveaux derives de l'amino-3 quinuclidine, leur procede et leur application en therapeutique
US4593034A (en) * 1984-04-06 1986-06-03 A. H. Robins Company, Inc. 2-alkoxy-N-(1-azabicyclo[2.2.2]oct-3-yl)benzamides and thiobenzamides
US4605652A (en) * 1985-02-04 1986-08-12 A. H. Robins Company, Inc. Method of enhancing memory or correcting memory deficiency with arylamido (and arylthioamido)-azabicycloalkanes
EP0385517B1 (fr) * 1985-03-14 1993-04-14 BEECHAM GROUP plc Médicaments pour le traitement du vomissement
GB8511988D0 (en) * 1985-05-11 1985-06-19 Beecham Group Plc Compounds
ES2051753T3 (es) * 1986-12-16 1994-07-01 Robins Co Inc A H N-(1-azabiciclo(2.2.2)octo-3-il) benzamidas y tiobenzamidas ansioliticas.

Also Published As

Publication number Publication date
AU2183488A (en) 1989-03-09
GB8720805D0 (en) 1987-10-14
US4877794A (en) 1989-10-31
CA1318595C (fr) 1993-06-01
EP0306345A3 (en) 1989-06-14
DK492688A (da) 1989-03-05
IL87662A0 (en) 1989-02-28
DK492688D0 (da) 1988-09-05
DE3880240D1 (de) 1993-05-19
JPH0269417A (ja) 1990-03-08
ATE88091T1 (de) 1993-04-15
EP0306345B1 (fr) 1993-04-14
DE3880240T2 (de) 1993-10-28
AU614768B2 (en) 1991-09-12
EP0306345A2 (fr) 1989-03-08
PH25429A (en) 1991-07-01

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