ZA894544B - Renin inhibiting isosteric peptide derivatives and of pharmaceutical compositions containing the same - Google Patents

Renin inhibiting isosteric peptide derivatives and of pharmaceutical compositions containing the same

Info

Publication number
ZA894544B
ZA894544B ZA894544A ZA894544A ZA894544B ZA 894544 B ZA894544 B ZA 894544B ZA 894544 A ZA894544 A ZA 894544A ZA 894544 A ZA894544 A ZA 894544A ZA 894544 B ZA894544 B ZA 894544B
Authority
ZA
South Africa
Prior art keywords
isosteric
same
pharmaceutical compositions
compositions containing
peptide derivatives
Prior art date
Application number
ZA894544A
Other languages
English (en)
Inventor
Jan Olle Karlsson
Olle Karlsson Jan
Erik Morgan Herman Sohtell
Morgan Herman Sohtell Erik
Rolf Christer Westerlund
Christer Westerlund Rolf
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Publication of ZA894544B publication Critical patent/ZA894544B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/14—Angiotensins: Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/28—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to acyclic carbon atoms of the carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Vascular Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
ZA894544A 1988-06-28 1989-06-14 Renin inhibiting isosteric peptide derivatives and of pharmaceutical compositions containing the same ZA894544B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8802428A SE8802428D0 (sv) 1988-06-28 1988-06-28 New compounds

Publications (1)

Publication Number Publication Date
ZA894544B true ZA894544B (en) 1990-07-25

Family

ID=20372758

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894544A ZA894544B (en) 1988-06-28 1989-06-14 Renin inhibiting isosteric peptide derivatives and of pharmaceutical compositions containing the same

Country Status (14)

Country Link
EP (1) EP0353211A1 (pt)
JP (1) JPH0285245A (pt)
KR (1) KR900000383A (pt)
CN (1) CN1039028A (pt)
AU (1) AU3671189A (pt)
DD (1) DD284027A5 (pt)
DK (1) DK300989A (pt)
FI (1) FI893118A7 (pt)
HU (1) HUT51291A (pt)
NO (1) NO892564L (pt)
PT (1) PT90992A (pt)
SE (1) SE8802428D0 (pt)
YU (1) YU132789A (pt)
ZA (1) ZA894544B (pt)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7032391A (en) * 1989-12-22 1991-07-24 Astra Aktiebolag New amides
US5314920A (en) * 1992-07-20 1994-05-24 G. D. Searle & Co. Ethynyl-alanine aryl/alkylsulfonyl-terminated amino-diol compounds for treatment of hypertension
US5317039A (en) * 1992-07-20 1994-05-31 G. D. Searle & Co. Cyclopropyl-alanine aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
US8168616B1 (en) 2000-11-17 2012-05-01 Novartis Ag Combination comprising a renin inhibitor and an angiotensin receptor inhibitor for hypertension
KR20010088472A (ko) * 2001-07-19 2001-09-28 이강섭 석재, 철, 콘크리트, 목재, 플라스틱 등 기존의 모든물건의 바탕에 자연적으로 대리석 무늬를 형성하는 공법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4645759A (en) * 1984-06-22 1987-02-24 Abbott Laboratories Renin inhibiting compounds
JPS63503380A (ja) * 1986-01-16 1988-12-08 アボット・ラボラトリーズ ペプチド類似体
WO1988002374A2 (en) * 1986-09-30 1988-04-07 The Upjohn Company Renin inhibitory peptides having novel c-terminal moieties
SE8605573D0 (sv) * 1986-12-29 1986-12-29 Haessle Ab Novel compounds

Also Published As

Publication number Publication date
DD284027A5 (de) 1990-10-31
DK300989A (da) 1989-12-29
KR900000383A (ko) 1990-01-30
JPH0285245A (ja) 1990-03-26
PT90992A (pt) 1989-12-29
HUT51291A (en) 1990-04-28
FI893118A7 (fi) 1989-12-29
SE8802428D0 (sv) 1988-06-28
EP0353211A1 (en) 1990-01-31
YU132789A (sh) 1992-09-07
AU3671189A (en) 1990-01-04
NO892564D0 (no) 1989-06-21
FI893118A0 (fi) 1989-06-27
CN1039028A (zh) 1990-01-24
NO892564L (no) 1989-12-29
DK300989D0 (da) 1989-06-19

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