ZA895121B - Fr901228 substance and preparation thereof - Google Patents

Fr901228 substance and preparation thereof

Info

Publication number
ZA895121B
ZA895121B ZA895121A ZA895121A ZA895121B ZA 895121 B ZA895121 B ZA 895121B ZA 895121 A ZA895121 A ZA 895121A ZA 895121 A ZA895121 A ZA 895121A ZA 895121 B ZA895121 B ZA 895121B
Authority
ZA
South Africa
Prior art keywords
substance
preparation
ferm
chem
production
Prior art date
Application number
ZA895121A
Other languages
English (en)
Inventor
Masakuni Okuhara
Okuhara Masakuni
Toshio Goto
Goto Toshio
Yasuhiro Hori
Hori Yasuhiro
Takashi Fujita
Fujita Takashi
Hirotsuqu Ueda
Ueda Hirotsuqu
Nobuharu Shigematsu
Shigematsu Nobuharu
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=10641100&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ZA895121(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of ZA895121B publication Critical patent/ZA895121B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/10—Tetrapeptides
    • C07K5/1002—Tetrapeptides with the first amino acid being neutral
    • C07K5/1005—Tetrapeptides with the first amino acid being neutral and aliphatic
    • C07K5/101—Tetrapeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Reinforced Plastic Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)
ZA895121A 1988-07-26 1989-07-05 Fr901228 substance and preparation thereof ZA895121B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888817743A GB8817743D0 (en) 1988-07-26 1988-07-26 Fr901228 substance & preparation thereof

Publications (1)

Publication Number Publication Date
ZA895121B true ZA895121B (en) 1990-08-29

Family

ID=10641100

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA895121A ZA895121B (en) 1988-07-26 1989-07-05 Fr901228 substance and preparation thereof

Country Status (16)

Country Link
US (1) US4977138A (fr)
EP (1) EP0352646B1 (fr)
JP (1) JPH0764872B2 (fr)
CN (1) CN1040054A (fr)
AT (1) ATE94561T1 (fr)
AU (1) AU3829089A (fr)
CA (1) CA1335083C (fr)
DE (1) DE68909139T2 (fr)
DK (1) DK366889A (fr)
ES (1) ES2058411T3 (fr)
FI (1) FI893359L (fr)
GB (1) GB8817743D0 (fr)
HU (1) HU211514A9 (fr)
IL (1) IL90949A0 (fr)
NO (1) NO893021L (fr)
ZA (1) ZA895121B (fr)

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US5130414A (en) * 1989-11-30 1992-07-14 Arizona Board Of Regents, A Body Corporate Of Arizona State University Isolation and structural elucidation of the cyclic peptide hymenistatin 1
JPH06247964A (ja) * 1993-02-22 1994-09-06 Snow Brand Milk Prod Co Ltd 新規生理活性物質ｈｓ−１及びその製造方法
PT932663E (pt) * 1996-11-22 2000-12-29 Pioneer Hi Bred Int Composicoes e metodos para eliminar a toxicidade da moniliformina
ATE331730T1 (de) * 1999-01-13 2006-07-15 Astellas Pharma Inc Neue depsipeptid-verbindung
CA2393682C (fr) * 1999-12-08 2012-01-31 Xcyte Therapies, Inc. Depsipeptide et ses congeneres destines a etre utilises en tant qu'immunodepresseurs
US6828302B1 (en) 1999-12-08 2004-12-07 Xcyte Therapies, Inc. Therapeutic uses of depsipeptides and congeners thereof
ATE425177T1 (de) * 2000-07-17 2009-03-15 Astellas Pharma Inc Reduziertes fk228 und seine verwendung
JP2004508049A (ja) * 2000-09-01 2004-03-18 藤沢薬品工業株式会社 Ｆｒ９０１２２８物質の製造法
DK1426054T3 (da) * 2001-08-21 2011-12-12 Astellas Pharma Inc Medicinsk anvendelse af histon-deacetylase-inhibitor og fremgangsmåde til evaluering af antitumor virkning deraf
US20040132643A1 (en) * 2002-01-09 2004-07-08 Fojo Antonio Tito Histone deacelylase inhibitors in diagnosis and treatment of thyroid neoplasms
US8673888B2 (en) * 2002-04-05 2014-03-18 The United States Of America, Represented By The Secretary, Department Of Health And Human Services Depsipeptide for therapy of kidney cancer
EP1595952A4 (fr) * 2003-02-19 2008-05-21 Astellas Pharma Inc Procede d'evaluation de l'effet antitumoral d'un inhibiteur d'histone desacetylase
DK2238982T3 (da) * 2003-06-27 2013-01-28 Astellas Pharma Inc Terapeutisk middel til blødt væv-sarcom
CA2540108A1 (fr) 2003-09-25 2005-04-07 Astellas Pharma Inc. Agent antitumoral comprenant un inhibiteur de l'histone desacetylase et un inhibiteur de la topoisomerase ii
WO2005058298A2 (fr) * 2003-12-10 2005-06-30 Wisconsin Alumni Research Foundation Analogues de fk228 et methodes de production et d'utilisation desdits analogues
US20050187148A1 (en) * 2004-02-25 2005-08-25 Yoshinori Naoe Antitumor agent
US7951780B2 (en) * 2004-02-25 2011-05-31 Astellas Pharma Inc. Antitumor agent
WO2005115149A2 (fr) * 2004-05-20 2005-12-08 Dow Agrosciences Llc Activite insecticide d'un peptide cyclique
JP2008520682A (ja) * 2004-11-17 2008-06-19 ザ ユニヴァーシティー オヴ シカゴ ヒストンデアセチラーゼ阻害剤およびその使用方法
GB0511266D0 (en) * 2005-06-02 2005-07-13 Trust Chemical compounds
EP1965824A4 (fr) * 2005-11-18 2011-10-19 Gloucester Pharmaceuticals Inc Dérivés de métabolites de l'inhibiteur de hdac fk228
CA2649877A1 (fr) * 2006-04-24 2007-12-21 Gloucester Pharmaceuticals Therapie de combinaison de gemcitabine
WO2007146730A2 (fr) * 2006-06-08 2007-12-21 Gloucester Pharmaceuticals Thérapie à base d'inhibiteurs de désacétylase (dac)
JP2010514801A (ja) * 2006-12-29 2010-05-06 グラスター ファーマシューティカルズ， インコーポレイテッド ロミデプシンの精製
CA2674313A1 (fr) * 2006-12-29 2008-07-10 Gloucester Pharmaceuticals, Inc. Traitements du cancer a base de romidepsine
WO2008098199A2 (fr) * 2007-02-08 2008-08-14 Uwm Research Foundation, Inc. Séquences utilisables pour la biosynthèse de fk228 et procédés de synthèse de fk228 et d'analogues de fk228
US20110060021A1 (en) * 2009-08-19 2011-03-10 Yiqiang Cheng Histone deacetylase inhibitors and uses thereof
AR080234A1 (es) 2010-02-25 2012-03-21 Marrone Bio Innovations Inc Cepa bacteriana aislada del genero burkholderia y metabolitos pesticidas del mismo
MX342913B (es) 2010-07-12 2016-10-19 Celgene Corp * Formas solidas de romidepsina y sus usos.
US8859502B2 (en) 2010-09-13 2014-10-14 Celgene Corporation Therapy for MLL-rearranged leukemia
WO2013032693A2 (fr) * 2011-08-27 2013-03-07 Marrone Bio Innovations, Inc. Souche bactérienne isolée du gène burkholderia et métabolites pesticides dérivés de cette souche, formulations et utilisations
CN104114182A (zh) 2011-09-23 2014-10-22 细胞基因公司 罗米地辛和5-阿扎胞苷在治疗淋巴瘤中的应用
CN104039330A (zh) 2011-09-26 2014-09-10 细胞基因公司 化疗耐药性的癌症的联合治疗
JP6214397B2 (ja) 2011-09-30 2017-10-18 国立大学法人東北大学 新規ホスファチジルイノシトール３キナーゼ阻害剤及び医薬組成物
WO2013085902A1 (fr) 2011-12-05 2013-06-13 The University Of Texas M.D. Procédés de polythérapie pour le traitement d'un cancer du sein inflammatoire
MX2014008390A (es) 2012-01-12 2014-09-22 Celgene Corp Formulaciones de romidepsina y sus usos.
AU2013202506B2 (en) 2012-09-07 2015-06-18 Celgene Corporation Resistance biomarkers for hdac inhibitors
AU2013202507B9 (en) 2012-11-14 2015-08-13 Celgene Corporation Inhibition of drug resistant cancer cells
CN103877010B (zh) * 2012-12-21 2018-06-01 正大天晴药业集团股份有限公司 一种罗米地辛溶液的制备方法
US9006462B2 (en) 2013-02-28 2015-04-14 Dermira, Inc. Glycopyrrolate salts
US8558008B2 (en) 2013-02-28 2013-10-15 Dermira, Inc. Crystalline glycopyrrolate tosylate
ES2699257T3 (es) 2013-02-28 2019-02-08 Dermira Inc Sales de glicopirrolato
CN103173390B (zh) * 2013-03-16 2014-09-10 浙江海正药业股份有限公司 一种紫色杆菌菌株及其应用
CN104072589B (zh) * 2013-03-29 2017-09-22 浙江海正药业股份有限公司 抗肿瘤三硫化合物及其制备方法与应用
CN104447950A (zh) * 2013-09-18 2015-03-25 上海医药工业研究院 一种罗米地辛的分离纯化方法
CN104450837B (zh) * 2013-09-18 2019-01-01 上海医药工业研究院 一种用于生产罗米地辛的方法及发酵培养基
NZ630311A (en) 2013-12-27 2016-03-31 Celgene Corp Romidepsin formulations and uses thereof
US10294276B2 (en) * 2014-03-04 2019-05-21 Concord Biotech Limited Process for isolation of romidepsin from fermentation broth and preparation of crystals of romidepsin
CN104894195B (zh) * 2014-03-07 2018-11-13 上海医药工业研究院 一种提高fk228产量的发酵培养基
CN104262456B (zh) * 2014-09-11 2018-01-09 浙江海正药业股份有限公司 一种罗米地辛的新晶型及其制备方法和用途
EP3313420B1 (fr) 2015-06-25 2024-03-13 The Children's Medical Center Corporation Procédés et compositions se rapportant à l'expansion, l'enrichissement et la conservation de cellules souches hématopoïétiques
WO2017068596A1 (fr) * 2015-10-20 2017-04-27 Msn Laboratories Private Limited Procédé amélioré pour la préparation de (1s, 4s, 7z, 10s, 16e, 21r)- 7-éthylidène-4,21-bis(1-méthyléthyl)-2-oxa-12,13-dithia-5, 8, 20, 23- tétraazabicyclo[8.7.6]tricos-16-ène-3, 6, 9, 19, 22-pentone
WO2017161001A1 (fr) 2016-03-15 2017-09-21 Children's Medical Center Corporation Procédés et compositions concernant l'expansion de cellules souches hématopoïétiques
EP3893647A1 (fr) 2018-12-14 2021-10-20 Pioneer Hi-Bred International, Inc. Produits biologiques et leur utilisation chez des végétaux
EP3902908A4 (fr) * 2018-12-24 2024-01-03 Pro Farm Group, Inc. Méthode d'augmentation de production de romidepsine à partir d'un bouillon de fermentation

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006065A1 (fr) * 1985-04-18 1986-10-23 Pfizer Inc. Produit de transformation de thiosporamicine
DE3782199T2 (de) * 1986-07-08 1993-02-25 Takeda Chemical Industries Ltd Biologisch aktive peptide tan-866.
US4777160A (en) * 1986-09-18 1988-10-11 Bristol-Myers BU-2867T peptide antibiotics

Also Published As

Publication number Publication date
ES2058411T3 (es) 1994-11-01
EP0352646A2 (fr) 1990-01-31
CN1040054A (zh) 1990-02-28
DE68909139T2 (de) 1994-02-10
FI893359A7 (fi) 1990-01-27
US4977138A (en) 1990-12-11
AU3829089A (en) 1990-02-01
NO893021L (no) 1990-01-29
DE68909139D1 (de) 1993-10-21
GB8817743D0 (en) 1988-09-01
DK366889A (da) 1990-01-27
JPH0764872B2 (ja) 1995-07-12
IL90949A0 (en) 1990-02-09
EP0352646A3 (en) 1990-10-31
FI893359L (fi) 1990-01-27
EP0352646B1 (fr) 1993-09-15
DK366889D0 (da) 1989-07-25
HU211514A9 (en) 1995-11-28
ATE94561T1 (de) 1993-10-15
NO893021D0 (no) 1989-07-25
FI893359A0 (fi) 1989-07-11
CA1335083C (fr) 1995-04-04
JPH0285296A (ja) 1990-03-26

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