ZA89639B - Triazolo(1,5-c)pyrimido(1,4)azines as bronchodilators - Google Patents

Triazolo(1,5-c)pyrimido(1,4)azines as bronchodilators

Info

Publication number: ZA89639B
Authority: ZA; South Africa
Prior art keywords: alkyl; azines; pyrimido; triazolo; compounds
Prior art date: 1988-02-05

Application number

ZA89639A

Other languages

English (en)

Inventor

James Joseph Wade

Joseph Wade James

Original Assignee

Riker Laboratories Inc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-02-05

Filing date

1989-01-26

Publication date

1990-09-26

1989-01-26 Application filed by Riker Laboratories Inc filed Critical Riker Laboratories Inc

1990-09-26 Publication of ZA89639B publication Critical patent/ZA89639B/xx

Links

229940124630 bronchodilator Drugs 0.000 title abstract 2
239000000168 bronchodilator agent Substances 0.000 title 1
125000000217 alkyl group Chemical group 0.000 abstract 5
150000001875 compounds Chemical class 0.000 abstract 3
125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 2
229910052739 hydrogen Inorganic materials 0.000 abstract 2
239000001257 hydrogen Substances 0.000 abstract 2
125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
125000002777 acetyl group Chemical group [H]C([H])([H])C(*)=O 0.000 abstract 1
230000007883 bronchodilation Effects 0.000 abstract 1
125000002915 carbonyl group Chemical group [*:2]C([*:1])=O 0.000 abstract 1
230000000694 effects Effects 0.000 abstract 1
230000001939 inductive effect Effects 0.000 abstract 1
239000000543 intermediate Substances 0.000 abstract 1
-1 methylene, carbonyl Chemical group 0.000 abstract 1
125000000325 methylidene group Chemical group [H]C([H])=* 0.000 abstract 1
239000008194 pharmaceutical composition Substances 0.000 abstract 1
230000000144 pharmacologic effect Effects 0.000 abstract 1
230000003389 potentiating effect Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains three hetero rings
- C07D513/14—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Pulmonology (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

ZA89639A 1988-02-05 1989-01-26 Triazolo(1,5-c)pyrimido(1,4)azines as bronchodilators ZA89639B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US15244388A	1988-02-05	1988-02-05

Publications (1)

Publication Number	Publication Date
ZA89639B true ZA89639B (en)	1990-09-26

Family

ID=22542946

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA89639A ZA89639B (en)	1988-02-05	1989-01-26	Triazolo(1,5-c)pyrimido(1,4)azines as bronchodilators

Country Status (11)

Country	Link
EP (1)	EP0327284B1 (de)
JP (1)	JP2694990B2 (de)
KR (1)	KR890013026A (de)
AT (1)	ATE110079T1 (de)
AU (1)	AU596764B2 (de)
CA (1)	CA1331178C (de)
DE (1)	DE68917491T2 (de)
DK (1)	DK47489A (de)
IE (1)	IE64917B1 (de)
NZ (1)	NZ227720A (de)
ZA (1)	ZA89639B (de)

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
JPS50116498A (de) *	1974-02-27	1975-09-11
DK135184A (da) *	1983-03-03	1984-10-10	Riker Laboratories Inc	Triazol(4,3-c)- og triazol(1,5-c)pyrimidiner
US4572910A (en) *	1983-03-03	1986-02-25	Riker Laboratories, Inc.	Triazolo[1,5-c]pyrimidines substituted by nitrogen-containing heterocyclic rings
EP0181282A1 (de) *	1984-10-01	1986-05-14	Ciba-Geigy Ag	Triazolochinazolinverbindungen
DE3677445D1 (de) *	1985-09-30	1991-03-14	Ciba Geigy Ag	2-substituierte-e-kondensierte(1,5-c)-pyrimidine, pharmazeutische zubereitungen und ihre verwendung.
US4639445A (en) *	1985-10-25	1987-01-27	Riker Laboratories	Metabolites of triazolo[1,5-c]pyrimidines
HU195822B (en) *	1985-12-30	1988-07-28	Gyogyszerkutato Intezet	Process for producing new pyrimido/5,4-b//1,h/oxazine derivatives
DE3781080T2 (de) *	1986-09-30	1992-12-24	Ciba Geigy Ag	2-substituierte-e-kondensierte(1,2,4)triazolo-(1,5-c)pyrimidine, pharmazeutische zubereitungen und ihre verwendung.
US4734413A (en) *	1987-03-02	1988-03-29	Riker Laboratories, Inc.	Substituted 1,2,4-triazolo[1,5-A]triazines as bronchodilators

1989
- 1989-01-24 IE IE21089A patent/IE64917B1/en not_active IP Right Cessation
- 1989-01-24 CA CA000589003A patent/CA1331178C/en not_active Expired - Fee Related
- 1989-01-25 NZ NZ227720A patent/NZ227720A/xx unknown
- 1989-01-26 ZA ZA89639A patent/ZA89639B/xx unknown
- 1989-01-30 EP EP89300876A patent/EP0327284B1/de not_active Expired - Lifetime
- 1989-01-30 DE DE68917491T patent/DE68917491T2/de not_active Expired - Fee Related
- 1989-01-30 AT AT89300876T patent/ATE110079T1/de active
- 1989-02-02 DK DK047489A patent/DK47489A/da not_active Application Discontinuation
- 1989-02-03 AU AU29598/89A patent/AU596764B2/en not_active Ceased
- 1989-02-04 KR KR1019890001335A patent/KR890013026A/ko not_active Abandoned
- 1989-02-06 JP JP1027333A patent/JP2694990B2/ja not_active Expired - Lifetime

Also Published As

Publication number	Publication date
AU596764B2 (en)	1990-05-10
CA1331178C (en)	1994-08-02
NZ227720A (en)	1992-10-28
DK47489A (da)	1989-09-21
DE68917491T2 (de)	1995-02-16
IE64917B1 (en)	1995-09-20
IE890210L (en)	1989-08-05
EP0327284A3 (de)	1991-05-02
JP2694990B2 (ja)	1997-12-24
KR890013026A (ko)	1989-09-20
DK47489D0 (da)	1989-02-02
EP0327284B1 (de)	1994-08-17
DE68917491D1 (de)	1994-09-22
EP0327284A2 (de)	1989-08-09
JPH02149584A (ja)	1990-06-08
ATE110079T1 (de)	1994-09-15
AU2959889A (en)	1989-08-10

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