ZA897020B - Derivatives of human/bovine basic fibroblast growth factor - Google Patents

Derivatives of human/bovine basic fibroblast growth factor

Info

Publication number
ZA897020B
ZA897020B ZA897020A ZA897020A ZA897020B ZA 897020 B ZA897020 B ZA 897020B ZA 897020 A ZA897020 A ZA 897020A ZA 897020 A ZA897020 A ZA 897020A ZA 897020 B ZA897020 B ZA 897020B
Authority
ZA
South Africa
Prior art keywords
derivatives
human
bfgf
growth factor
fibroblast growth
Prior art date
Application number
ZA897020A
Other languages
English (en)
Inventor
Laura Bergonzoni
Bergonzoni Laura
Antonella Isacchi
Isacchi Antonella
Paolo Sarmientos
Sarmientos Paolo
Gilles Gauet
Gauet Gilles
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of ZA897020B publication Critical patent/ZA897020B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/50—Fibroblast growth factor [FGF]
    • C07K14/503—Fibroblast growth factor [FGF] basic FGF [bFGF]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Dermatology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Eye Examination Apparatus (AREA)
ZA897020A 1988-09-16 1989-09-14 Derivatives of human/bovine basic fibroblast growth factor ZA897020B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB888821795A GB8821795D0 (en) 1988-09-16 1988-09-16 New derivatives of human/bovine basic fibroplast growth factor

Publications (1)

Publication Number Publication Date
ZA897020B true ZA897020B (en) 1990-08-29

Family

ID=10643728

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA897020A ZA897020B (en) 1988-09-16 1989-09-14 Derivatives of human/bovine basic fibroblast growth factor

Country Status (21)

Country Link
EP (2) EP0363675B1 (fr)
JP (1) JP2888575B2 (fr)
KR (1) KR900702027A (fr)
CN (1) CN1041181A (fr)
AT (1) ATE98693T1 (fr)
AU (1) AU620925B2 (fr)
CA (1) CA1340834C (fr)
DE (1) DE68911461T2 (fr)
DK (1) DK120290A (fr)
ES (1) ES2061855T3 (fr)
FI (1) FI902391A7 (fr)
GB (1) GB8821795D0 (fr)
HU (1) HUT53937A (fr)
IL (1) IL91615A0 (fr)
MY (1) MY104910A (fr)
NO (1) NO902176L (fr)
NZ (1) NZ230621A (fr)
PT (1) PT91719B (fr)
WO (1) WO1990002800A1 (fr)
YU (1) YU179489A (fr)
ZA (1) ZA897020B (fr)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5143829A (en) * 1990-03-29 1992-09-01 California Biotechnology Inc. High level expression of basic fibroblast growth factor having a homogeneous n-terminus
US5478804A (en) * 1990-09-19 1995-12-26 The Salk Institute For Biological Studies Treatment of tumorigenic pathophysiological conditions with FGF-cytoxic conjugates
JP3135138B2 (ja) * 1990-12-19 2001-02-13 科研製薬株式会社 骨疾患治療剤
US6833354B1 (en) 1990-12-19 2004-12-21 Kaken Pharmaceutical Co., Ltd. Agent for the treatment of bone diseases
EP0505108B1 (fr) * 1991-03-21 1995-10-18 The Procter & Gamble Company Compositions régulatrices des rides de la peau contenant des peptides comportant la séquence arg-ser-arg-lys
JP3303211B2 (ja) * 1991-04-26 2002-07-15 武田薬品工業株式会社 ｂＦＧＦムテインおよびその製造法
TW275068B (fr) * 1993-09-24 1996-05-01 American Cyanamid Co
AUPO247496A0 (en) 1996-09-23 1996-10-17 Resmed Limited Assisted ventilation to match patient respiratory need
US6214795B1 (en) * 1996-11-12 2001-04-10 Praecis Pharmaceuticals, Inc. Peptide compounds useful for modulating FGF receptor activity
US6274712B1 (en) 1997-12-23 2001-08-14 3-Dimensional Pharmaceuticals, Inc. Analogs of human basic fibroblast growth factor mutated at one or more of the positions glutamute 89, aspartate 101 or leucine 137
FR2780416B1 (fr) * 1998-06-10 2002-12-20 Rhone Poulenc Nutrition Animal Procede industriel de production de proteines heterologues chez e. coli et souches utiles pour le procede
AU6634400A (en) 1999-08-13 2001-03-13 Chiron Corporation Dose of an angiogenic factor and method of administering to improve myocardial blood flow
WO2001046416A1 (fr) * 1999-12-22 2001-06-28 3-Dimensional Pharmaceuticals, Inc. Analogues du facteur de croissance fibroblastique basique humain
ES2305138T3 (es) 2000-11-27 2008-11-01 Dnavec Research Inc. Vector de paramixovirus que codifica factor 2 de crecimiento de fibroblastos (fgf2) y uso del mismo.
US8772460B2 (en) * 2011-12-16 2014-07-08 Wisconsin Alumni Research Foundation Thermostable FGF-2 mutant having enhanced stability
CN106957359B (zh) * 2016-08-31 2020-04-24 黄志锋 Fgf1突变体及其医药应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989000198A1 (fr) * 1987-07-07 1989-01-12 Biotechnology Research Associates, J.V. Facteurs de croissance de fibroblastes recombinants
DK122687A (da) * 1986-03-14 1987-09-15 Takeda Chemical Industries Ltd Polypeptid, dna og anvendelse deraf
JPH01501840A (ja) * 1987-01-16 1989-06-29 アムジエン・インコーポレーテツド 繊維芽細胞成長因子の産生
JP2526965B2 (ja) * 1987-02-24 1996-08-21 武田薬品工業株式会社 ムテイン，ｄｎａおよびその用途
EP0326907A1 (fr) * 1988-01-26 1989-08-09 Takeda Chemical Industries, Ltd. Polypeptide, DNA et leur utilisation

Also Published As

Publication number Publication date
MY104910A (en) 1994-06-30
PT91719B (pt) 1995-05-31
EP0363675B1 (fr) 1993-12-15
AU620925B2 (en) 1992-02-27
JP2888575B2 (ja) 1999-05-10
YU179489A (en) 1991-10-31
CA1340834C (fr) 1999-11-30
PT91719A (pt) 1990-03-30
GB8821795D0 (en) 1988-10-19
JPH03501855A (ja) 1991-04-25
DK120290A (da) 1990-07-16
NO902176D0 (no) 1990-05-15
EP0363675A1 (fr) 1990-04-18
HU895573D0 (en) 1990-11-28
FI902391A0 (fi) 1990-05-14
NO902176L (no) 1990-07-13
CN1041181A (zh) 1990-04-11
DE68911461D1 (de) 1994-01-27
AU4317189A (en) 1990-04-02
EP0396664A1 (fr) 1990-11-14
ATE98693T1 (de) 1994-01-15
DE68911461T2 (de) 1994-05-19
ES2061855T3 (es) 1994-12-16
WO1990002800A1 (fr) 1990-03-22
NZ230621A (en) 1992-06-25
FI902391A7 (fi) 1990-05-14
DK120290D0 (da) 1990-05-15
IL91615A0 (en) 1990-04-29
HUT53937A (en) 1990-12-28
KR900702027A (ko) 1990-12-05

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