ZA897587B - Substituted 9h-purines - Google Patents

Substituted 9h-purines

Info

Publication number: ZA897587B
Authority: ZA; South Africa
Prior art keywords: purines; substituted
Prior art date: 1988-10-06

Application number

ZA897587A

Other languages

English (en)

Inventor

Hans Allgeier

Allgeier Hans

Original Assignee

Ciba Geigy

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-10-06

Filing date

1989-10-05

Publication date

1990-05-30

1989-10-05 Application filed by Ciba Geigy filed Critical Ciba Geigy

1990-05-30 Publication of ZA897587B publication Critical patent/ZA897587B/xx

Links

KDCGOANMDULRCW-UHFFFAOYSA-N 7H-purine Chemical class N1=CNC2=NC=NC2=C1 KDCGOANMDULRCW-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

ZA897587A 1988-10-06 1989-10-05 Substituted 9h-purines ZA897587B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
CH373188		1988-10-06

Publications (1)

Publication Number	Publication Date
ZA897587B true ZA897587B (en)	1990-05-30

Family

ID=4262288

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA897587A ZA897587B (en)	1988-10-06	1989-10-05	Substituted 9h-purines

Country Status (17)

Country	Link
US (1)	US5110818A (fr)
EP (1)	EP0363320A3 (fr)
JP (1)	JPH02157279A (fr)
KR (1)	KR900006337A (fr)
AU (1)	AU632763B2 (fr)
CA (1)	CA2000154A1 (fr)
DD (1)	DD297820A5 (fr)
DK (1)	DK491389A (fr)
FI (1)	FI894707A7 (fr)
HU (1)	HUT52502A (fr)
IL (1)	IL91818A (fr)
MX (1)	MX17846A (fr)
NO (1)	NO172986C (fr)
NZ (1)	NZ230898A (fr)
PH (1)	PH27154A (fr)
PT (1)	PT91895B (fr)
ZA (1)	ZA897587B (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US5391739A (en) *	1989-03-29	1995-02-21	Merrell Dow Pharmaceuticals Inc.	Selective adenosine receptor agents
US5387684A (en) *	1992-03-25	1995-02-07	The Green Cross Corporation	Isoindazole compound
FR2699176B1 (fr) *	1992-12-11	1995-03-03	Adir	Nouveaux composés bicycliques de pyrimidine, leur procédé de préparation et les compositions pharmaceutiques les renfermant.
GB9312853D0 (en) *	1993-06-22	1993-08-04	Euro Celtique Sa	Chemical compounds
US5994361A (en) *	1994-06-22	1999-11-30	Biochem Pharma	Substituted purinyl derivatives with immunomodulating activity
US5591776A (en) *	1994-06-24	1997-01-07	Euro-Celtique, S.A.	Pheynl or benzyl-substituted rolipram-based compounds for and method of inhibiting phosphodiesterase IV
US5922751A (en) *	1994-06-24	1999-07-13	Euro-Celtique, S.A.	Aryl pyrazole compound for inhibiting phosphodiesterase IV and methods of using same
DE19535504A1 (de) *	1995-09-25	1997-03-27	Bayer Ag	Substituierte Xanthine
US6166041A (en) *	1995-10-11	2000-12-26	Euro-Celtique, S.A.	2-heteroaryl and 2-heterocyclic benzoxazoles as PDE IV inhibitors for the treatment of asthma
FR2741881B1 (fr) *	1995-12-01	1999-07-30	Centre Nat Rech Scient	Nouveaux derives de purine possedant notamment des prorietes anti-proliferatives et leurs applications biologiques
US6075016A (en) *	1996-04-10	2000-06-13	Euro-Celtique S.A.	6,5-fused aromatic ring systems having enhanced phosphodiesterase IV inhibitory activity
US6294541B1 (en)	1996-06-06	2001-09-25	Euro-Celtique S.A.	Purine derivatives having phosphodiesterase IV inhibition activity
US5864037A (en)	1996-06-06	1999-01-26	Euro-Celtique, S.A.	Methods for the synthesis of chemical compounds having PDE-IV inhibitory activity
CN1294590A (zh)	1997-12-12	2001-05-09	欧罗赛铁克股份有限公司	通过2－硫代黄嘌呤制备3－取代腺嘌呤的方法
US6319928B1 (en)	1998-11-30	2001-11-20	Euro-Celtique, S.A.	Purine derivatives having phosphodiesterase IV inhibition activity
CA2367143A1 (fr)	1999-04-02	2000-10-12	Euro-Celtique S.A.	Derives de purine possedant une activite d'inhibition de la phosphodiesterase iv
US7439359B2 (en) *	2000-11-02	2008-10-21	Sloan-Kettering Institute For Cancer Research	Small molecule compositions for binding to hsp90
WO2003037860A2 (fr) *	2001-10-30	2003-05-08	Conforma Therapeutics Corporation	Analogues de purine presentant une activite inhibitrice de hsp90
US20070129334A1 (en) *	2001-10-30	2007-06-07	Conforma Therapeutics Corporation	Orally Active Purine-Based Inhibitors of Heat Shock Protein 90
MXPA06002997A (es) *	2003-09-18	2007-02-08	Conforma Therapeutics Corp	Novedosos compuestos heterociclicos como inhibidores- hsp90.
AU2006230447A1 (en)	2005-03-30	2006-10-05	Conforma Therapeutics Corporation	Alkynyl pyrrolopyrimidines and related analogs as HSP90-inhibitors
WO2007035963A2 (fr) *	2005-09-23	2007-03-29	Conforma Therapeutics Corporation	Methodes antitumorales dans lesquelles sont utilises des inhibiteurs de hsp90 de synthese independants de la multiresistance aux medicaments
WO2009034386A1 (fr) *	2007-09-13	2009-03-19	Astrazeneca Ab	Dérivés de l'adénine et de la 8-aza-adénine et leurs utilisations

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US3846426A (en) *	1971-03-03	1974-11-05	Int Minerals & Chem Corp	6-amino-9-(substituted benzyl) purines and their n{11 oxides
GB1534163A (en) *	1976-07-28	1978-11-29	Merck & Co Inc	Adenine derivatives
USRE31429E (en) *	1977-02-14	1983-10-25	Merck & Co., Inc.	Process for preparation of 9-(dihalobenzyl)adenines
GB1547214A (en) *	1977-08-09	1979-06-06	Merck & Co Inc	Purine derivatives
US4189485A (en) *	1977-08-23	1980-02-19	Takeda Chemical Industries, Ltd.	Purine derivatives
US4361699A (en) *	1981-09-28	1982-11-30	Merck & Co., Inc.	Novel process for the preparation of N6 -alkyl-arprinocid
EP0108285B1 (fr) *	1982-10-14	1988-04-20	The Wellcome Foundation Limited	Dérivés de purine antiviraux
US4748177A (en) *	1984-03-26	1988-05-31	Warner-Lambert Company	Guanine derivatives
GB8408615D0 (en) *	1984-04-04	1984-05-16	Wellcome Found	Heterocyclic compounds
KR910700253A (ko) *	1989-01-31	1991-03-14	로버트 제이, 바란	N_6-치환-9-메틸아데닌: 신규한 부류의 아데노신 수용체 길항질

1989
- 1989-09-26 EP EP19890810731 patent/EP0363320A3/fr not_active Withdrawn
- 1989-09-28 IL IL9181889A patent/IL91818A/en not_active IP Right Cessation
- 1989-10-04 DD DD89333303A patent/DD297820A5/de not_active IP Right Cessation
- 1989-10-04 PT PT91895A patent/PT91895B/pt not_active IP Right Cessation
- 1989-10-04 PH PH39332A patent/PH27154A/en unknown
- 1989-10-04 NZ NZ230898A patent/NZ230898A/xx unknown
- 1989-10-04 CA CA002000154A patent/CA2000154A1/fr not_active Abandoned
- 1989-10-04 FI FI894707A patent/FI894707A7/fi not_active IP Right Cessation
- 1989-10-05 ZA ZA897587A patent/ZA897587B/xx unknown
- 1989-10-05 DK DK491389A patent/DK491389A/da not_active Application Discontinuation
- 1989-10-05 MX MX17846A patent/MX17846A/es unknown
- 1989-10-05 AU AU42612/89A patent/AU632763B2/en not_active Ceased
- 1989-10-05 JP JP1258944A patent/JPH02157279A/ja active Pending
- 1989-10-05 HU HU895224A patent/HUT52502A/hu unknown
- 1989-10-05 NO NO893965A patent/NO172986C/no unknown
- 1989-10-06 KR KR1019890014356A patent/KR900006337A/ko not_active Withdrawn
1990
- 1990-12-19 US US07/630,401 patent/US5110818A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
IL91818A0 (en)	1990-06-10
CA2000154A1 (fr)	1990-04-06
EP0363320A3 (fr)	1991-11-21
JPH02157279A (ja)	1990-06-18
IL91818A (en)	1994-08-26
PT91895A (pt)	1990-04-30
DK491389D0 (da)	1989-10-05
FI894707A0 (fi)	1989-10-04
DK491389A (da)	1990-04-07
PT91895B (pt)	1995-05-31
NO893965D0 (no)	1989-10-05
NO893965L (no)	1990-04-09
AU632763B2 (en)	1993-01-14
KR900006337A (ko)	1990-05-07
FI894707A7 (fi)	1990-04-07
NZ230898A (en)	1992-12-23
PH27154A (en)	1993-04-02
MX17846A (es)	1994-03-31
NO172986B (no)	1993-06-28
US5110818A (en)	1992-05-05
AU4261289A (en)	1990-04-12
DD297820A5 (de)	1992-01-23
HUT52502A (en)	1990-07-28
NO172986C (no)	1993-10-06
EP0363320A2 (fr)	1990-04-11

Publication	Publication Date	Title
DE3991334D2 (en)	1991-04-04	Elastische kniegelenkbandage
IL91818A0 (en)	1990-06-10	Substituted 9h-purines
AU105058S (en)	1989-09-14	Sunlounger
DE3990051D2 (en)	1991-01-10	Gaslaser
ZA898779B (en)	1990-07-25	Substituted oxadiaminobutanes
BG47752A1 (en)	1990-09-14	Reductor- evaporator
ZA893738B (en)	1990-01-31	Substituted dibenzothiaphenes
BG49585A1 (en)	1991-12-16	Anemorumbometer
DE3990052D2 (de)	1991-10-10	Fenster- oder tuereinheit
ZA892857B (en)	1989-12-27	Substituted triazolylmethylcarbinols
DE3990355D2 (en)	1990-04-05	Lichtleiterkoppler
ZA893170B (en)	1989-12-27	3-cyano-4-phenyl-pyrroles
CS275265B2 (en)	1992-02-19	Arthroendoprosthesis
CA60525S (en)	1988-03-22	Cheeseboard
CA60669S (en)	1988-04-19	Chevalet
DE3990058D2 (en)	1990-11-22	Langlaufskibindungsanordnung
DE3990624D2 (en)	1990-07-19	Systemwerkzeug
CA60421S (en)	1988-03-08	Wax-applicator
DE3990515D2 (en)	1990-08-30	2-komponenten-bindemittel
IE880784L (en)	1988-09-17	Substituted 9-amino-tetrahydroacridines
SU1592288A2 (ru)	1990-09-15	Metahtehk
BG46508A1 (en)	1990-01-15	Deltaplane
CS836388A1 (en)	1989-09-12	6-maleateimido-2-n-propylthiobenzothiazole
CS2888A1 (en)	1989-06-13	Biocontactor
GB8813470D0 (en)	1988-07-13	Combath