ZA899832B - Human somatomedin carrier protein subunits and process for producing them;recombinant dna molecules,hosts,processes and human somatomedian carrier protein-like polypeptides - Google Patents
Human somatomedin carrier protein subunits and process for producing them;recombinant dna molecules,hosts,processes and human somatomedian carrier protein-like polypeptidesInfo
- Publication number
- ZA899832B ZA899832B ZA899832A ZA899832A ZA899832B ZA 899832 B ZA899832 B ZA 899832B ZA 899832 A ZA899832 A ZA 899832A ZA 899832 A ZA899832 A ZA 899832A ZA 899832 B ZA899832 B ZA 899832B
- Authority
- ZA
- South Africa
- Prior art keywords
- carrier protein
- human
- polypeptides
- dna molecules
- processes
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title abstract 8
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 8
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 8
- 238000000034 method Methods 0.000 title abstract 7
- 108090000723 Insulin-Like Growth Factor I Proteins 0.000 title abstract 6
- 102000013275 Somatomedins Human genes 0.000 title abstract 6
- 102000014914 Carrier Proteins Human genes 0.000 title abstract 5
- 108010078791 Carrier Proteins Proteins 0.000 title abstract 5
- 108020004511 Recombinant DNA Proteins 0.000 title abstract 4
- 108020004414 DNA Proteins 0.000 abstract 4
- 230000004071 biological effect Effects 0.000 abstract 1
- 238000011210 chromatographic step Methods 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 210000002966 serum Anatomy 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4743—Insulin-like growth factor binding protein
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/575—Hormones
- C07K14/62—Insulins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/06—Drugs for disorders of the endocrine system of the anterior pituitary hormones, e.g. TSH, ACTH, FSH, LH, PRL, GH
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Diabetes (AREA)
- Endocrinology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Molecular Biology (AREA)
- Rheumatology (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Obesity (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Nutrition Science (AREA)
- Ophthalmology & Optometry (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Saccharide Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US29025088A | 1988-12-22 | 1988-12-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA899832B true ZA899832B (en) | 1990-10-31 |
Family
ID=23115154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA899832A ZA899832B (en) | 1988-12-22 | 1989-12-21 | Human somatomedin carrier protein subunits and process for producing them;recombinant dna molecules,hosts,processes and human somatomedian carrier protein-like polypeptides |
Country Status (14)
| Country | Link |
|---|---|
| EP (2) | EP0375438A3 (fr) |
| JP (2) | JPH04503352A (fr) |
| KR (1) | KR910700261A (fr) |
| AT (1) | ATE155793T1 (fr) |
| AU (1) | AU4836890A (fr) |
| CA (1) | CA2006322C (fr) |
| DE (1) | DE68928203T2 (fr) |
| DK (1) | DK95291A (fr) |
| ES (1) | ES2107422T3 (fr) |
| GR (1) | GR3025094T3 (fr) |
| HK (1) | HK1000826A1 (fr) |
| IL (1) | IL92816A0 (fr) |
| WO (1) | WO1990006950A1 (fr) |
| ZA (1) | ZA899832B (fr) |
Families Citing this family (24)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5258287A (en) * | 1988-03-22 | 1993-11-02 | Genentech, Inc. | DNA encoding and methods of production of insulin-like growth factor binding protein BP53 |
| US5198340A (en) * | 1991-01-17 | 1993-03-30 | Genentech, Inc. | Assay for free igf-i, igf-ii, and gh levels in body fluids |
| US5187151A (en) * | 1991-02-12 | 1993-02-16 | Genentech, Inc. | Use of binding protein with igf-i as an anabolic growth promoting agent |
| US5643867A (en) * | 1992-08-26 | 1997-07-01 | Celtrix Pharmaceuticals, Inc. | Method for treating catabolic conditions |
| CA2195474A1 (fr) * | 1994-07-20 | 1996-02-01 | Cedo Martin Bagi | Complexe igf/igfbp pour promouvoir la formation de tissu osseux et pour reguler le remodelage osseux |
| US5565204A (en) * | 1994-08-24 | 1996-10-15 | American Cyanamid Company | Pneumococcal polysaccharide-recombinant pneumolysin conjugate vaccines for immunization against pneumococcal infections |
| US6420518B1 (en) | 1997-04-04 | 2002-07-16 | Genetech, Inc. | Insulin-like growth factor agonist molecules |
| US6121416A (en) | 1997-04-04 | 2000-09-19 | Genentech, Inc. | Insulin-like growth factor agonist molecules |
| AU762351B2 (en) | 1999-01-06 | 2003-06-26 | Genentech Inc. | Insulin-like growth factor (IGF) I mutant variants |
| JP2002535967A (ja) | 1999-01-06 | 2002-10-29 | ジェネンテック・インコーポレーテッド | インシュリン様成長因子(igf)i変異体 |
| ATE389416T1 (de) | 2000-05-16 | 2008-04-15 | Genentech Inc | Behandlung von knorpelerkrankungen |
| WO2002072780A2 (fr) | 2001-03-14 | 2002-09-19 | Genentech, Inc. | Peptides antagonistes d'igf |
| CA2524305C (fr) | 2003-05-01 | 2015-12-08 | Imclone Systems Incorporated | Anticorps entierement humains diriges contre le recepteur du facteur de croissance 1 de type insuline |
| EP2274978B1 (fr) | 2003-09-12 | 2015-05-20 | Tercica, Inc. | Méthodes de traitement de la déficience du facteur de croissance de type insuline 1 (IGF-1) |
| US7192738B2 (en) | 2003-10-03 | 2007-03-20 | Genentech, Inc. | IGF binding proteins |
| CA2612449A1 (fr) | 2005-06-17 | 2006-12-28 | Imclone Systems Incorporated | Antagonistes de recepteur pour le traitement de cancer osseux metastatique |
| AP2008004569A0 (en) | 2006-02-03 | 2008-08-31 | Imclone Systems Inc | IGR-IR antagonists as adjuvants for treatment of prostrate cancer |
| CA3075482A1 (fr) | 2017-09-11 | 2019-03-14 | Shire Human Genetic Therapies, Inc. | Procedes et compositions pour traiter des maladies pulmonaires chroniques |
| MX2023004426A (es) | 2020-10-19 | 2023-08-04 | Oak Hill Bio Ltd | Composiciones adecuadas para su uso en neonatos. |
| AU2023210427A1 (en) | 2022-01-19 | 2024-08-22 | Oak Hill Bio Limited | Compositions and methods for reducing oxidation of igf‐1/igfbp |
| WO2023242439A1 (fr) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Stabilisation vasculaire (nourrissons prématurés) |
| WO2023242442A1 (fr) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Procédé de maturation/différenciation de neurones et/ou de modulation du nerf vague |
| WO2023242440A1 (fr) | 2022-06-17 | 2023-12-21 | Oak Hill Bio Limited | Traitement des poumons chez les nourrissons |
| CN120882420A (zh) | 2023-02-14 | 2025-10-31 | 奥克希尔生物有限公司 | Gi组织中愈合失调的治疗 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL68218A (en) * | 1983-03-23 | 1985-12-31 | Univ Ramot | Compositions for cartilage repair comprising embryonal chondrocytes |
| US4738921A (en) * | 1984-09-27 | 1988-04-19 | Eli Lilly And Company | Derivative of the tryptophan operon for expression of fused gene products |
| US4861757A (en) * | 1986-11-14 | 1989-08-29 | Institute Of Molecular Biology | Wound healing and bone regeneration using PDGF and IGF-I |
| US4885163A (en) * | 1987-02-24 | 1989-12-05 | Eli Lilly And Company | Topical use of IGF-II for wound healing |
| IL89661A (en) * | 1988-03-17 | 1999-05-09 | Novo Nordisk As | Heparin binding proteins |
| US5258287A (en) * | 1988-03-22 | 1993-11-02 | Genentech, Inc. | DNA encoding and methods of production of insulin-like growth factor binding protein BP53 |
| ATE132164T1 (de) * | 1988-04-12 | 1996-01-15 | Amgen Boulder Inc | Verfahren zur steigerung und zur hemmung der wirkung eines insulinähnlichen wachstumfaktors |
-
1989
- 1989-12-20 IL IL92816A patent/IL92816A0/xx unknown
- 1989-12-21 JP JP2501912A patent/JPH04503352A/ja active Pending
- 1989-12-21 DE DE68928203T patent/DE68928203T2/de not_active Revoked
- 1989-12-21 AT AT90901407T patent/ATE155793T1/de not_active IP Right Cessation
- 1989-12-21 KR KR1019900701824A patent/KR910700261A/ko not_active Withdrawn
- 1989-12-21 ZA ZA899832A patent/ZA899832B/xx unknown
- 1989-12-21 EP EP19890313463 patent/EP0375438A3/fr active Pending
- 1989-12-21 AU AU48368/90A patent/AU4836890A/en not_active Abandoned
- 1989-12-21 CA CA002006322A patent/CA2006322C/fr not_active Expired - Fee Related
- 1989-12-21 WO PCT/US1989/005791 patent/WO1990006950A1/fr not_active Ceased
- 1989-12-21 EP EP90901407A patent/EP0451194B1/fr not_active Revoked
- 1989-12-21 ES ES90901407T patent/ES2107422T3/es not_active Expired - Lifetime
- 1989-12-21 HK HK97102385A patent/HK1000826A1/en not_active IP Right Cessation
-
1991
- 1991-05-21 DK DK095291A patent/DK95291A/da unknown
-
1997
- 1997-10-20 GR GR970402735T patent/GR3025094T3/el unknown
-
1998
- 1998-10-23 JP JP10303047A patent/JPH11236400A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA2006322A1 (fr) | 1990-06-22 |
| JPH04503352A (ja) | 1992-06-18 |
| ATE155793T1 (de) | 1997-08-15 |
| GR3025094T3 (en) | 1998-01-30 |
| DK95291A (da) | 1991-08-16 |
| IL92816A0 (en) | 1990-09-17 |
| HK1000826A1 (en) | 1998-05-01 |
| EP0375438A3 (fr) | 1992-03-25 |
| AU4836890A (en) | 1990-07-10 |
| EP0451194A1 (fr) | 1991-10-16 |
| DE68928203D1 (de) | 1997-09-04 |
| WO1990006950A1 (fr) | 1990-06-28 |
| DK95291D0 (da) | 1991-05-21 |
| KR910700261A (ko) | 1991-03-14 |
| EP0451194A4 (en) | 1992-09-02 |
| JPH11236400A (ja) | 1999-08-31 |
| ES2107422T3 (es) | 1997-12-01 |
| EP0451194B1 (fr) | 1997-07-23 |
| CA2006322C (fr) | 2000-08-01 |
| DE68928203T2 (de) | 1998-01-15 |
| EP0375438A2 (fr) | 1990-06-27 |
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