ZA902709B - Dichloro-substituted imidazole derivatives as antifungal agents - Google Patents

Dichloro-substituted imidazole derivatives as antifungal agents

Info

Publication number: ZA902709B
Authority: ZA; South Africa
Prior art keywords: dichloro; products; formula; antifungal agents; imidazole derivatives
Prior art date: 1989-04-10

Application number

ZA902709A

Other languages

English (en)

Inventor

Romeo Andreoli Rovatti

Andreoli Rovatti Romeo

Ricardo Cepero Mestres

Cepero Mestres Ricardo

Original Assignee

Espanola Farma Therapeut

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-04-10

Filing date

1990-04-09

Publication date

1991-01-30

1990-04-09 Application filed by Espanola Farma Therapeut filed Critical Espanola Farma Therapeut

1991-01-30 Publication of ZA902709B publication Critical patent/ZA902709B/xx

Links

-1 Dichloro-substituted imidazole Chemical class 0.000 title abstract 2
229940121375 antifungal agent Drugs 0.000 title 1
239000003429 antifungal agent Substances 0.000 title 1
229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 abstract 3
RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 abstract 3
OCAPBUJLXMYKEJ-UHFFFAOYSA-N 1-[biphenyl-4-yl(phenyl)methyl]imidazole Chemical compound C1=NC=CN1C(C=1C=CC(=CC=1)C=1C=CC=CC=1)C1=CC=CC=C1 OCAPBUJLXMYKEJ-UHFFFAOYSA-N 0.000 abstract 1
GRYLNZFGIOXLOG-UHFFFAOYSA-N Nitric acid Chemical compound O[N+]([O-])=O GRYLNZFGIOXLOG-UHFFFAOYSA-N 0.000 abstract 1
230000000843 anti-fungal effect Effects 0.000 abstract 1
230000001857 anti-mycotic effect Effects 0.000 abstract 1
239000002543 antimycotic Substances 0.000 abstract 1
229960002206 bifonazole Drugs 0.000 abstract 1
229960004022 clotrimazole Drugs 0.000 abstract 1
VNFPBHJOKIVQEB-UHFFFAOYSA-N clotrimazole Chemical compound ClC1=CC=CC=C1C(N1C=NC=C1)(C=1C=CC=CC=1)C1=CC=CC=C1 VNFPBHJOKIVQEB-UHFFFAOYSA-N 0.000 abstract 1
229910052736 halogen Inorganic materials 0.000 abstract 1
150000002367 halogens Chemical class 0.000 abstract 1
229910017604 nitric acid Inorganic materials 0.000 abstract 1
150000003839 salts Chemical class 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
- C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
- C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
- C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Agricultural Chemicals And Associated Chemicals (AREA)

ZA902709A 1989-04-10 1990-04-09 Dichloro-substituted imidazole derivatives as antifungal agents ZA902709B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
ES8901237A ES2012297A6 (es)	1989-04-10	1989-04-10	Procedimiento para la obtencion de nuevos derivados imidazolicos diclorados con actividad antifungica.

Publications (1)

Publication Number	Publication Date
ZA902709B true ZA902709B (en)	1991-01-30

Family

ID=8261371

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
ZA902709A ZA902709B (en)	1989-04-10	1990-04-09	Dichloro-substituted imidazole derivatives as antifungal agents

Country Status (14)

Country	Link
EP (1)	EP0392326B1 (pt)
JP (1)	JP2798094B2 (pt)
KR (1)	KR960007164B1 (pt)
AT (1)	ATE108778T1 (pt)
AU (1)	AU627010B2 (pt)
CA (1)	CA2014202C (pt)
DE (1)	DE69010729T2 (pt)
DK (1)	DK0392326T3 (pt)
ES (2)	ES2012297A6 (pt)
HK (1)	HK1007429A1 (pt)
LV (1)	LV11461B (pt)
NZ (1)	NZ233269A (pt)
PT (1)	PT93707B (pt)
ZA (1)	ZA902709B (pt)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2092957B1 (es) *	1994-11-28	1997-08-01	S A L V A T Lab Sa	Procedimiento de preparacion de intermedios para la sintesis de derivados dicloro-substituidos con actividad antifungica.
CA2572223C (en)	2004-06-25	2014-08-12	The Johns Hopkins University	Angiogenesis inhibitors

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1593417A (en) *	1976-12-22	1981-07-15	Squibb & Sons Inc	Carbocyclic-fused pyrazolopyridine derivatives
US4826853A (en) *	1986-10-31	1989-05-02	Schering Corporation	6,11-Dihydro-11-(N-substituted-4-piperidylidene)-5H-benzo(5,6)cyclohepta(1,2-B)pyridines and compositions and methods of use

1989
- 1989-04-10 ES ES8901237A patent/ES2012297A6/es not_active Expired - Fee Related
1990
- 1990-04-04 AT AT90106404T patent/ATE108778T1/de not_active IP Right Cessation
- 1990-04-04 DE DE69010729T patent/DE69010729T2/de not_active Expired - Lifetime
- 1990-04-04 DK DK90106404.8T patent/DK0392326T3/da active
- 1990-04-04 AU AU52554/90A patent/AU627010B2/en not_active Expired
- 1990-04-04 EP EP90106404A patent/EP0392326B1/en not_active Expired - Lifetime
- 1990-04-04 ES ES90106404T patent/ES2057235T3/es not_active Expired - Lifetime
- 1990-04-09 ZA ZA902709A patent/ZA902709B/xx unknown
- 1990-04-09 PT PT93707A patent/PT93707B/pt not_active IP Right Cessation
- 1990-04-09 CA CA002014202A patent/CA2014202C/en not_active Expired - Lifetime
- 1990-04-10 NZ NZ233269A patent/NZ233269A/xx unknown
- 1990-04-10 JP JP2093248A patent/JP2798094B2/ja not_active Expired - Lifetime
- 1990-04-10 KR KR1019900004874A patent/KR960007164B1/ko not_active Expired - Lifetime
1995
- 1995-07-14 LV LVP-95-214A patent/LV11461B/en unknown
1998
- 1998-06-25 HK HK98106627A patent/HK1007429A1/en not_active IP Right Cessation

Also Published As

Publication number	Publication date
KR960007164B1 (ko)	1996-05-29
ATE108778T1 (de)	1994-08-15
AU627010B2 (en)	1992-08-13
CA2014202A1 (en)	1990-10-10
DK0392326T3 (da)	1994-08-22
PT93707B (pt)	1996-08-30
ES2012297A6 (es)	1990-03-01
JP2798094B2 (ja)	1998-09-17
DE69010729T2 (de)	1994-11-24
PT93707A (pt)	1990-11-20
LV11461A (lv)	1996-08-20
AU5255490A (en)	1990-10-11
JPH0372462A (ja)	1991-03-27
DE69010729D1 (de)	1994-08-25
NZ233269A (en)	1991-08-27
LV11461B (en)	1997-02-20
CA2014202C (en)	1997-02-04
EP0392326B1 (en)	1994-07-20
KR900016143A (ko)	1990-11-12
ES2057235T3 (es)	1994-10-16
HK1007429A1 (en)	1999-04-09
EP0392326A1 (en)	1990-10-17

Publication	Publication Date	Title
NO174508C (pt)	1994-05-18
AU3812689A (en)	1990-01-18	Derivatives of n-phenylpyrazoles
NO964871L (no)	1996-11-15	Nye agonistforbindelser
PL309355A1 (en)	1995-10-02	Substituted pyrazoles as crf antagonists
AU6464290A (en)	1991-04-26	Use of substituted imidazoles
IT1255802B (it)	1995-11-16	Derivati imidazolici ad attivita' a ii antagonista
FI942499A0 (fi)	1994-05-27	Indolijohdannainen, menetelmä sen valmistamiseksi ja sen lääkekäyttö
AU627010B2 (en)	1992-08-13	Dichloro-substituted imidazole derivatives as antifungal agents
IL112364A0 (en)	1995-03-30	Pharmaceutical compositions containing 3-phenylsulphonyl-3,7-diazabicyclo (3.3.1) nonane for the treatment of cardiac arrhythmias
AU561097B2 (en)	1987-04-30	Imidazole derivatives
ES2092957A1 (es)	1996-12-01	Procedimiento de preparacion de intermedios para la sintesis de derivados dicloro-substituidos con actividad antifungica.
HU903953D0 (en)	1990-11-28	Process for producing imidazole derivatives
ATE84034T1 (de)	1993-01-15	Imidazol-derivate, verfahren zu deren herstellung und deren anwendung als alpha-2-adrenoceptor- antagonisten.